
潘岳松,流行病与卫生统计学博士,首都医科大学附属北京天坛医院介入神经病学科副主任,国家神经系统疾病临床医学研究中心研究员、副教授、博士生导师。任中国卒中学会脑健康分会常务委员兼秘书长、中华医学会临床流行病学和循证医学分会方法学组委员、中国卒中学会青年理事会理事、北京医学会临床流行病学和循证医学分会青年委员、北京市慢性病防治与健康教育研究会医疗健康大数据专业委员会常务委员。主持国自然面上项目,十四五国家重点研发计划课题,入选北京市高层次公共卫生技术人才学科带头人,北京市医院管理局“青苗”计划,首都医科大学青年学者,主要开展脑血管病临床流行病学、临床试验与临床研究。作为业务骨干参与CNSR-I/II/III、CHANCE-I/II/III、TRACE-I/II/III、ANGEL-ASPECT、CATIS-2、INSPIRES等多项全国多中心临床队列与临床试验课题的研究工作,相关文章发表于NEJM, Lancet, JAMA, BMJ等杂志。获国家科学技术进步奖二等奖、浙江省科学技术进步奖三等奖各1项,以第一作者或通讯作者发表SCI论文100余篇,其中发表BMJ 1篇,Lancet Neurol 1篇, Circulation 2篇, JAMA Neurol 4篇,JAMA Network Open 2篇,eBioMedicine 2篇,Eur J Epidemiol 1篇,Ann Neurol 1篇,Neurology 7篇,Stroke 15篇。2023年(排名:96827)与2024年(排名:85226)入选美国斯坦福大学
“全球前2%顶尖科学家-年度科学影响力排行榜”( World's Top 2% Scientists)。
1.2024.06-2025.05,国家重点研发计划“新型冠状病毒感染后认知障碍的临床研究”项目-“社区成年人长新冠感染对认知功能的影响研究”课题,主持。
2.2024.1-2026.12,北京市高层次公共卫生技术人才(学科带头人),“脑血管病防治干预的卫生经济学评价研究”课题,主持。
3.2022.12-2025.12,国家重点研发计划“老年血管疾病整体化防控模式与技术研究”项目-“老年血管疾病医护在线培训系统和示范区建设”课题,主持。
4. 2022.1-2023.12,首都医科大学优秀青年人才项目,“缺血性脑血管病精准抗血小板治疗策略”,主持。
5. 2020.1-2023.12,国家自然科学基金面上项目“胰岛素抵抗对缺血性卒中预后的影响及其慢性炎症机制研究”,主持。
6. 2020.1-2021.12,入选北京市医院管理中心2019年度(第五批)“青苗”计划“胰岛素抵抗与颅颈动脉狭窄斑块的相关性及其机制研究”, 主持。
7. 2018.8-2020.12,“十三五”国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项,“重大慢病流行病学监测大数据平台构建和关键技术研究” ,参与单位负责人。
代表性论文:
1. Zhou Q#, Gao Y, Chen W, Johnston SC, Amarenco P, Bath PM, Wang X, Yan H, Wang T, Yang Y, Zhang Y, Yang Q, Wang M, Jing J, Wang C, Wang Y, Wang Y*, Pan Y*. Efficacy and Safety of Dual Antiplatelet Treatment up to 72 Hours in Acute Ischemic Stroke Stratified by Glycemic Status. Ann Neurol. 2025; (in press) (IF=8.1)
2. Yang Y#, Cai X#, Zhou M, Chen Y, Pi J, Zhao M, Shi Y, Jing J, Chen W, Yan H, Meng X, Wang Y, Pan Y*, Wang Y*. Association of Left Ventricular Function With Cerebral Small Vessel Disease in a Community-Based Population. CNS Neurosci Ther. 2025;31(2):e70226. (IF=4.8)
3. Zhang R#, Yao D#, Cai X, Zhang Y, Yang Y, Li S, Jing J, Wang S, Wang Y, Pan Y*, Wang Y*. Prevalence and Risk Factors of Covert Brain Infarction: a Community-based Cross-sectional Study. Int J Stroke. 2025; (in press) (IF= 6.3)
4. Wang M#, Yan H, Zhang Y, Zhou Q, Meng X, Lin J, Jiang Y, Pan Y*, Wang Y*. Accelerated biological aging increases the risk of short- and long-term stroke prognosis in patients with ischemic stroke or TIA. eBioMedicine. 2025; 111:105494. (IF= 9.7)
5. Zhang Y#, Wang X#, Gao Y, Chen W, Johnston SC, Amarenco P, Bath PM, Yan H, Wang T, Yang Y, Zhou Q, Wang M, Jing J, Wang C, Wang Y, Wang Y*, Pan Y*. Dual Antiplatelet Treatment up to 72 Hours After Ischemic Stroke Stratified by Risk Profile: A Post Hoc Analysis. Stroke. 2025;56(1):46-55. (IF=7.8)
6. Zhang Y#, Pan Y#, Yan H, Meng X, Lin J, Wang M, Li H, Xu Q, Chen P, Wang A, Zhou Y*, Wang Y*. Prognostic Impact of 1-Year Changes in Creatinine- and Cystatin C-Based Estimated Glomerular Filtration Rate After Stroke on 5-Year Outcomes: Insights From the Third China National Stroke Registry. J Am Heart Assoc. 2025 Jan 16:e037579. (IF=5.0)
7. Zhang Y#, Wang M#, Cai X, Jin A, Jing J, Wang S, Meng X, Li S, Zhou Q, Wang X, Wei T, Wang Y, Pan Y*. Associations of non-insulin-based insulin resistance indices with presence and extent of multi-territorial atherosclerosis: A cross-sectional study. J Clin Lipidol. 2025; (in press). (IF=3.6)
8. Zhou Q#, Zhu W#, Cai X, Jing J, Wang M, Wang S, Jin A, Meng X, Wei T, Wang Y, Pan Y*. Obesity and brain volumes: mediation by cardiometabolic and inflammatory measures. Stroke Vasc Neurol. 2025; (in press). (IF=4.4)
9. Zhou Q, Cai X, Jin A, Jing J, Wang M, Wang S, Mei L, Meng X, Shan L, Wei T, Wang Y, Liu L*, Pan Y*. Associations between adipose tissue-specific insulin resistance and atherosclerotic plaques and burden in community-based population. Neuroepidemiology. 2025; (in press). (IF=3.2)
10. Wang D#, Pan Y#, Cai X#, Jing J, Yan H, Wang S, Meng X, Mei L, Zhang Y, Li S, Wei T, Zhou Y*, Wang Y*. Prevalence and Associated Factors of Atherosclerotic Plaque and Stenosis in Renal Arteries: A Community-Based Study. Angiology. 2025; (in press). (IF=2.6)
11. Liu Y#, Zhao J#, Gao Y, Chen W, Johnston SC, Bath PM, Amarenco P, Yan H, Wang X, Yang Y, Wang T, Wang Y, Pan Y*, Wang Y*. Clopidogrel and Aspirin Initiated Between 24 to 72 Hours for Mild Ischemic Stroke: A Subgroup Analysis of the INSPIRES Randomized Clinical Trial. JAMA Netw Open. 2024;7(9):e2431938. (IF=10.5)
12. Guan L#, Han S, Johnston SC, Bath PM, Amarenco P, Yang Y, Wang T, Jing J, Wang C, Gao Y, Chen W, Yan H, Wang X, Wang Y, Wang Y, Pan Y*. Duration of Benefit and Risk of Dual Antiplatelet Therapy up to 72 Hours After Mild Ischemic Stroke and Transient Ischemic Attack. Neurology. 2024; 103(7):e209845. (IF=7.7)
13. Liu D#, Zhang Y#, Cai X, Yang Y, Wang S, Mei L, Jing J, Li S, Wang M, Meng X, Wei T, Wang Y, Wang Y*, Pan Y*. Associations of 10-year atherosclerotic cardiovascular disease risk scores with cerebral small vessel disease: the PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events (PRECISE) study. Age Ageing. 2024;53(7):afae161. (IF= 6.0)
14. Zhou M#, Zhou Y#, Jing J, Wang M, Jin A, Cai X, Meng X, Liu T, Wang Y, Wang Y*, Pan Y*. Insulin Resistance and White Matter Microstructural Abnormalities in Nondiabetic Adult: A Population-Based Study. Int J Stroke. 2024;19(10):1162-1171. (IF= 6.3)
15. Zhang Y#, Liu D#, Cai X, Jin A, Mei L, Jing J, Wang S, Meng X, Li S, Wang M, Yan H, Wei T, Wang Y*, Pan Y*. Associations of life's essential 8 with extent of multi-territorial atherosclerotic plaques and stenosis: a cross-sectional study. BMC Geriatr. 2024;24(1):503. (IF=3.4)
16. Zhou M#, Mei L#, Jing J, Yang Y, Cai X, Meng X, Jin A, Lin J, Li S, Li H, Wei T, Wang Y, Wang Y*, Pan Y*. Blood Pressure Partially Mediated the Association of Insulin Resistance and Cerebral Small Vessel Disease: A Community-Based Study. J Am Heart Assoc. 2024; 13(5):e031723. (IF=5.0)
17. Meng Y#, Wang S#, Zhu W, Wang T, Liu D, Wang M, Pi J, Liu Y, Zhuo Z, Pan Y*, Wang Y*. Association of Mean Upper Cervical Spinal Cord Cross-Sectional Area With Cerebral Small Vessel Disease: A Community-Based Cohort Study. Stroke. 2024; 55(3):687-695. (IF=7.8)
18. Liu D#, Cai X, Yang Y, Wang S, Mei L, Jing J, Li S, Wang M, Chen Y, Meng X, Wei T, Wang Y, Wang Y*, Pan Y*. Association between Life's Essential 8 and Cerebral Small Vessel Disease. Stroke Vasc Neurol. 2024; 9(5):481-489. (IF=4.4)
19. Pan Y#, Huo X, Jin A, Nguyen TN, Ma G, Tong X, Zhang X, Gao F, Ma N, Mo D, Ren Z, Wang Y, Miao Z*. Cost-effectiveness of endovascular therapy for acute ischemic stroke with large infarct in China. J Neurointerv Surg. 2024; 16(5):453-458. (IF=4.5)
20. Yang Y#, Cai X#, Zhou M, Chen Y, Pi J, Zhao M, Shi Y, Wang S, Jing J, Chen W, Meng X, Wang Y, Pan Y*, Wang Y*. Prevalence and Risk Factors of Cerebral Small Vessel Disease from a Population-Based Cohort in China. Neuroepidemiology. 2023; 57(6):413-422. (IF=3.2)
21. Zhang Y#, Xia Z#, Cai X, Su X, Jin A, Mei L, Jing J, Wang S, Meng X, Li S, Wang M, Wei T, Wang Y*, He Y*, Pan Y*. Association of metabolic dysfunction-associated fatty liver disease with systemic atherosclerosis: a community-based cross-sectional study. Cardiovasc Diabetol. 2023; 22(1):342. (IF=8.5)
22. Zhou Q#, Yan H, Jin A, Meng X, Lin J, Li H, Wang Y, Pan Y*. Adipose tissue specific insulin resistance and prognosis of nondiabetic patients with ischemic stroke. Diabetol Metab Syndr. 2023;15(1):246. (IF=3.4)
23. Cai X#, Sun J#, Jin A, Jing J, Wang S, Mei L, Meng X, Li S, Wei T, Wang Y, Pan Y*. Association of insulin resistance with intra- and extra-cranial atherosclerotic burden in the nondiabetic community population. Neurobiol Dis. 2023;186:106268. (IF=5.1)
24. Wang Y#, Cai X#, Li H, Jin A, Jiang L, Chen W, Jing J, Mei L, Li S, Meng X, Wei T, Wang Y, Pan Y*, Wang Y*. Association of Intracranial Atherosclerosis with Cerebral Small Vessel Disease in Community-based Population. Eur J Neurol. 2023;30(9):2700–2712. (IF=4.5)
25. Zhang Y#, Pan Y#, Cai X#, Jing J, Yan H, Wang S, Meng X, Mei L, Zhang Y, Li S, Wei T, Zhou Y*, Wang Y*. Association between Urine Albumin-to-creatinine Ratio and Intracranial Atherosclerotic Plaque in Chinese Adults - Results from the PRECISE Study. J Atheroscler Thromb. 2023;30(12):1828-1837. (IF=3.0)
26. Tian Y#, Cai X#, Zhou Y, Jin A, Wang S, Yang Y, Mei L, Jing J, Li S, Meng X, Wei T, Liu T, Wang Y, Pan Y*, Wang Y*. Impaired glymphatic system as evidenced by low diffusivity along perivascular spaces is associated with cerebral small vessel disease: a population-based study. Stroke Vasc Neurol. 2023;8(5):413-423. (IF=4.4)
27. Zhou H#, Chen W, Suo Y, Meng X, Zhao X, Wang M, Liu L, Li H, Pan Y*, Wang Y*. External Validation of the Nelson Equation for Kidney Function Decline in Patients with Acute Ischemic Stroke or Transient Ischemic Attack. Clin Interv Aging. 2023; 18: 901-909. (IF=3.5)
28. Pan Y#, Shen J#, Cai X#, Chen H, Zong G, Zhu W, Jing J, Liu T, Jin A, Wang Y, Meng X, Yuan C*, Wang Y*. Adherence to a healthy lifestyle and brain structural imaging markers. Eur J Epidemiol. 2023;38(6):657-668. (IF= 7.7)
29. Pan Y#, Meng X#, Yuan B, Johnston SC, Li H, Bath PM, Dong Q, Xu A, Jing J, Lin J, Jiang Y, Xie X, Jin A, Suo Y, Yang H, Feng Y, Zhou Y, Liu Q, Li X, Liu B, Zhu H, Zhao J, Huang X, Li H, Xiong Y, Li Z, Wang Y, Zhao X, Liu L, Wang Y*; INSURE Investigators. Indobufen versus aspirin in patients with acute ischaemic stroke in China (INSURE): a randomised, double-blind, double-dummy, active control, non-inferiority trial. Lancet Neurol. 2023; 22(6):485-493. (IF=46.5)
30. Fang H#, Chen W#, Jin A, Wang M, Yan H, Xiang X, Pan Y*. Effects of genetically determined mineral status on life expectancy: a Mendelian randomization study. Chin Med J (Engl). 2023;136(2):242-244. (IF=7.5)
31. Tian Y#, Li S#, Yang Y, Cai X, Jing J, Wang S, Meng X, Mei L, Jin A, Yao D, Wei T, Wang Y, Pan Y*, Wang Y*. Associations of deep medullary veins with vascular risk factors, laboratory indicators, and cerebral small vessel disease: A population-based study. Brain Behav. 2023;13(5): e2974. (IF=2.6)
32. Jin A#, Wang S#, Li J, Wang M, Lin J, Li H, Meng X, Wang Y, Pan Y*. Mediation of systemic inflammation on insulin resistance and prognosis of nondiabetic patients with ischemic stroke. Stroke. 2023; 54(3):759-769. (IF=7.8)
33. Zhou M#, Wang S#, Jing J, Yang Y, Cai X, Meng X, Mei L, Lin J, Li S, Li H, Wei T, Wang Y, Pan Y*, Wang Y*. Insulin resistance based on postglucose load measure is associated with prevalence and burden of cerebral small vessel disease. BMJ Open Diabetes Res Care. 2022;10(5):e002897. (IF=3.7)
34. Wang M#, Mei L#, Jin A, Cai X, Jing J, Wang S, Meng X, Li S, Wei T, Wang Y, Pan Y*. Association between Triglyceride Glucose index and Atherosclerotic Plaques and Burden: Findings from a Community-Based Study. Cardiovasc Diabetol. 2022;21(1):204. (IF=8.5)
35. Xu Y#, Chen W#, Jiang L, Wang Y, Zhao X, Liu L, Yao D, Guo L, Wang Y, Pan Y*, Wang Y*. Aspirin platelet reactivity on platelet function and clinical outcome in minor stroke or transient ischemic attack. J Stroke Cerebrovasc Dis. 2022;31(9):106683. (IF=2.0)
36. Zhang Y, Jin A, Meng X, Wang M, Li H, Pan Y*, Wang Y*. Association between Diabetes Duration and 1-Year Prognosis of Stroke: A National Registry Study. Brain Behav. 2022; 12(9): e2725. (IF=2.6)
37. Pan Y#, Cai X#, Jing J, Wang S, Meng X, Mei L, Yang Y, Jin A, Yao D, Li S, Li H, Wei T, Wang Y*, Wang Y*. Differential Associations of Lipoprotein(a) Level with Cerebral Large Artery and Small Vessel Diseases. Stroke Vasc Neurol. 2022;7: e001625. (IF=4.4)
38. Liu D#, Cai X#, Yang Y, Wang S, Yao D, Mei L, Jing J, Li S, Yan H, Meng X, Li H, Wei T, Wang Y, Pan Y*, Wang Y*. Associations of Life's Simple 7 with Cerebral Small Vessel Disease. Stroke. 2022;53(9):2859-2867. (IF=7.8)
39. Jing J#, Zhou Y#, Pan Y#, Cai X#, Zhu W, Zhang Z, Li Z, Liu C, Meng X, Cheng J, Wang Y, Li H, Wu Z, Wang S, Niu H, Wen W, Liu T*, Wei T*, Wang Y*, Sachdev PS. Reduced White Matter Microstructural Integrity in Prediabetes and Diabetes: A Population-based Study. eBioMedicine. 2022; 82:104144. (IF= 9.7)
40. Jin A#, Wang M#, Chen W, Yan H, Xiang X, Pan Y*. Differential Effects of Genetically Determined Cholesterol Efflux Capacity on Coronary Artery Disease and Ischemic Stroke. Front Cardiovasc Med. 2022; 9:891148. (IF=2.8)
41. Pan Y#, Jing J#, Cai X#, Jin Z, Wang S, Wang Y, Zeng C, Meng X, Ji J, Li L, Lyu L, Zhang Z, Mei L, Li H, Li S, Wei T*, Wang Y*. Prevalence and Vascular Distribution of Multiterritorial Atherosclerosis Among Community-Dwelling Adults in Southeast China. JAMA Netw Open. 2022; 5(6):e2218307. (IF=10.5)
42. Yao D#, Li S#, Jing J, Cai X, Jin A, Yang Y, Wang S, Meng X, Lin J, Mei L, Li H, Wei T, Wang Y, Pan Y*, Wang Y*. Association of serum cystatin C with cerebral small vessel disease in community-based population. Stroke. 2022;53(10):3123-3132. (IF=7.8)
43. Jiang L#, Cai X#, Yang Y, Wang S, Jing J, Mei L, Jin A, Li S, Meng X, Li H, Wei T, Wang Y, Pan Y*, Wang Y*. Association of inflammatory markers with cerebral small vessel disease in community-based population. J Neuroinflammation.2022; 19(1):106. (IF=9.3)
44. Ma G#, Yu Z#, Jia B, Xian Y, Ren Z, Mo D, Ma N, Gao F, Tong X, Shi X, Li L, Pan Y*, Miao Z*; ANGEL-ACT study group. Time to Endovascular Reperfusion and Outcome in Acute Ischemic Stroke: A Nationwide Prospective Registry in China. Clin Neuroradiol. 2022;32(4):997-1009. (IF=2.4)
45. Pan Y, Meng X, Jin A, Johnston SC, Li H, Bath PM, Xie X, Jing J, Lin J, Wang Y, Zhao X, Li Z, Jiang Y, Liu L, Yang H, Cheng J, Wang Z, Wang Y*. Time course for benefit and risk of ticagrelor and aspirin in CYP2C19 loss-of-function carriers with acute ischemic stroke or transient ischemic attack: a secondary analysis from the CHANCE-2 randomized trial. JAMA Neurol.2022;79(8):739-745. (IF=20.4)
46. Pan Y#, Meng X#, Chen W, Jing J, Lin J, Jiang Y, Johnston SC, Bath PM, Dong Q, Xu A, Li H, Wang Y*. Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial. Stroke Vasc Neurol. 2022;7: e001480. (IF=4.4)
47. Wang Y*#, Pan Y#, Li H, Amarenco P, Denison H, Evans SR, Himmelmann A, James S, Knutsson M, Ladenvall P, Molina CA, Johnston SC*. Time course for benefit and risk of ticagrelor and aspirin in acute ischemic stroke or transient ischemic attack. Neurology. 2022; 99(1):e46-e54. (IF=7.7)
48. Pan Y#, Wangqin R#, Li H, Jin A, Li J, Lin J, Meng X, Xian Y, Laskowitz DT, Wang Y*. LDL-C Levels, Lipid Lowering Treatment and Recurrent Stroke in Minor Ischaemic Stroke or TIA. Stroke Vasc Neurol. 2022; 7: e001317. (IF=4.4)
49. Chen W#, Yao D#, Yan H, Wang M, Pan Y*. Genetically Predicted Childhood Obesity and Adult Atrial Fibrillation: a Mendelian Randomization Study. Nutr Metab Cardiovasc Dis. 2022; 32(4):1019-1026. (IF=3.3)
50. Zhou M, Li H, Wang Y, Pan Y*, Wang Y*. Causal effect of Insulin Resistance on Small Vessel Stroke and Alzheimer's Disease: A Mendelian Randomization Analysis. Eur J Neurol. 2022;29(3):698-706. (IF=4.5)
51. Wang D#, Pan Y#, Li H, Yan H, Meng X, Lin J, Wang H, Matsushita H, Shlipak MG, Zhou Y*, Wang Y*. The Association between Baseline and 3-Month Albuminuria and 1-Year Prognosis of Ischemic Stroke. Cerebrovasc Dis. 2022;51(1):67-74. (IF=2.2)
52. Chen W#, Cai X#, Yan H, Pan Y*. Causal Effect of Obstructive Sleep Apnea on Atrial Fibrillation: A Mendelian Randomization Study. J Am Heart Assoc. 2021;10(23):e022560. (IF=5.0)
53. Wang Y*#, Pan Y#, Li H, Amarenco P, Denison H, Evans SR, Himmelmann A, James S, Birve F, Ladenvall P, Molina CA, Johnston SC*; THALES Investigators. Efficacy and safety of ticagrelor and aspirin in patients with moderate ischemic stroke: an exploratory analysis of the THALES randomized clinical trial. JAMA Neurol. 2021;78(9):1091-1098. (IF=20.4)
54. Xiong Y#, Pan Y#, Nogueira RG, Ren Z, Jovin TG, Wang Y*. Treating acute large vessel occlusion stroke: to bridge or not to bridge? Stroke Vasc Neurol. 2021; 6(3):324-327. (IF=4.4)
55. Pan Y#, Li Z, Li J, Jin A, Lin J, Jing J, Li H, Meng X, Wang Y, Wang Y*. Residual risk and its risk factors for ischemic stroke with adherence to guideline-based secondary stroke prevention. J Stroke. 2021;23(1):51-60. (IF=6.0)
56. Pan Y#, Jing J#, Cai X#, Wang Y, Wang S, Meng X, Zeng C, Shi J, Ji J, Lin J, Lyu L, Zhang Z, Mei L, Li S, Li S, Zhu W, Li H, Wei T*, Wang Y*. PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events (PRECISE)- a population-based prospective cohort study: rationale, design and baseline participant characteristics. Stroke Vasc Neurol. 2021;6(1):145-151. (IF=4.4)
57. Pan Y#, Wangqin R#, Li H, Wang Y, Meng X, Johnston SC, Simon T, Lin J, Zhao X, Liu L, Wang D, Wang Y*. F2R polymorphisms and clopidogrel efficacy and safety in patients with minor stroke or TIA. Neurology. 2021; 96(1):e1-e9. (IF=7.7)
58. Pan Y, Li H, Wardlaw JM, Wang Y*. A new dawn of preventing dementia by preventing cerebrovascular diseases. BMJ. 2020;371:m3692. (IF=93.6)
59. Fang HJ#, Pan YS#, Wang YJ, Wang CX, Wang YL, Zhong LY*. Prognostic value of admission hyperglycemia on outcomes of thrombolysis in ischemic stroke patients with or without diabetes. Chin Med J (Engl). 2020;133(18):2244-2246. (IF=7.5)
60. Pan Y*, Chen W, Yan H, Wang M, Xiang X. Glycemic Traits and Alzheimer's Disease: A Mendelian Randomization Study. Aging (Albany NY). 2020; 12(22): 22688-22699. (IF=3.9)
61. Chen W#, Wang S#, Lv W, Pan Y*. Causal Associations of Insulin Resistance with Coronary Artery Disease and Ischaemic Stroke: A Mendelian Randomisation Analysis. BMJ Open Diabetes Res Care. 2020; 8(1). pii: e001217. (IF=3.7)
62. Yang Y#, Chen W, Meng X, Liu L, Wang Y, Pan Y*, Wang Y*. Impact of Smoking on Platelet Function of Ticagrelor Versus Clopidogrel in Minor Stroke or Transient Ischaemic Attack. Eur J Neurol. 2020; 27(5):833-840. (IF=4.5)
63. Jiang J#, Cai X#, Pan Y*, Yan Y, Zhu H, Yang X, Zheng D, Gaisano H, Wei T*, Yan H*. Relationship of obesity to adipose tissue insulin resistance. BMJ Open Diabetes Res Care. 2020; 8(1). pii: e000741. (IF=3.7)
64. Pan Y*, Zhang L, Li Z, Meng X, Wang Y, Li H, Liu L, Wang Y*. Cost-Effectiveness of a Multifaceted Quality Improvement Intervention for Acute Ischemic Stroke in China. Stroke. 2020;51(4):1265-1271. (IF=7.8)
65. Wen J#, Cai X#, Zhang J, Jiang J, Li W, Liu G, Wang M, Gaisano HY, Pan Y*, He Y*. Relation of adipose tissue insulin resistance to prediabetes. Endocrine. 2020; 68(1):93-102. (IF= 3.0)
66. Lin J#, Wang Y, Wang Y, Pan Y*. Inflammatory biomarkers and risk of ischemic stroke and subtypes: A 2-sample Mendelian randomization study. Neurol Res. 2020;42(2):118-125. (IF=1.7)
67. Liu H#, Zheng H#, Wu P, Liu CF, Wang D, Li H, Meng X, Wang Y, Cao Y, Wang Y, Pan Y*. Estimated glomerular filtration rate, anemia and outcomes in patients with ischemic stroke. Ann Transl Med. 2020;8(1):2. (IF=3.6)
68. Pan Y*, Wang Y, Wang Y. Investigation of Causal Effect of Atrial Fibrillation on Alzheimer's Disease: A Mendelian Randomization Study. J Am Heart Assoc. 2020;9(2):e014889. (IF=5.0)
69. Liu H#, Meng X#, Liu CF, Wang D, Zheng H, Li H, Liu L, Wang Y, Wang Y, Pan Y*. Higher Hemoglobin A1c Level Is Associated with Poor Outcome of Intracerebral Hemorrhage. Front Neurol. 2019; 10:1073. (IF=2.7)
70. Pan Y*, Li H, Wang Y, Meng X, Wang Y*. Causal Effect of Lp(a) [Lipoprotein(a)] Level on Ischemic Stroke and Alzheimer Disease: A Mendelian Randomization Study. Stroke. 2019;50(12):3532-3539. (IF=7.8)
71. Zhu B#, Pan Y*, Jing J, Meng X, Zhao X, Liu L, Wang Y, Wang Y, Wang Z*. Stress Hyperglycemia and Outcome of Non-diabetic Patients After Acute Ischemic Stroke. Front Neurol. 2019; 10:1003. (IF=2.7)
72. Pan Y#, Elm JJ#, Li H, Easton JD, Wang Y, Farrant M, Meng X, Kim AS, Zhao X, Meurer WJ, Liu L, Dietrich D, Wang Y*, Johnston SC*. Outcomes Associated With Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack: A Pooled Analysis of Clopidogrel in High-Risk Patients With Acute Non-Disabling Cerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trials. JAMA Neurol. 2019;76(12):1466-1473. (IF=20.4)
73. Wang T#, Pan Y#, Lin J, Anand R, Wang D, Johnston SC, Meng X, Li H, Zhao X, Liu L, Wang Y, Wang Y*; CHANCE investigators. Influence of smoking on CYP2C19 genetic variants and clopidogrel efficacy in patients with minor stroke or TIA. Eur J Neurol. 2019;26(9):1175-1182. (IF=4.5)
74. Sun S#, Pan Y#, Bai L, Zhao X, Liu L, Li H, Wang Y, Guo L*, Wang Y*. GWTG Risk Model for All Stroke Types Predicts In-Hospital and 3-Month Mortality in Chinese Patients with Acute Stroke. J Stroke Cerebrovasc Dis. 2019; 28(3):800-806. (IF=2.0)
75. Pan Y, Chen W, Wang Y*. Prediabetes and outcome of ischemic stroke or transient ischemic attack: a systematic review and meta-analysis. J Stroke Cerebrovasc Dis. 2019; 28(3):683-692. (IF=2.0)
76. Pan Y, Chen W, Wang Y, Li H, Johnston SC, Simon T, Zhao X, Liu L, Wang D, Meng X, Wang Y*. Association between ABCB1 Polymorphisms and Outcomes of Clopidogrel Treatment in Patients with Minor Stroke or Transient Ischemic Attack: Secondary Analysis of a Randomized Clinical Trial. JAMA Neurol. 2019;76(5):552-560. (IF=20.4)
77. Zhu B#, Liu H#, Pan Y#, Jing J, Li H, Zhao X, Liu L, Wang D, Johnston SC, Wang Z, Wang Y*, Wang Y*. Elevated Neutrophil and Presence of Intracranial Artery Stenosis Increase the Risk of Recurrent Stroke. Stroke. 2018; 49(10): 2294-2300. (IF=7.8)
78. Zhou Y#, Zhang Y#, Pan Y#, Jing J, Zhao X, Liu L, Wang C, Li H, Yan H, Meng X, Wang Y*, Wang Y*. Insulin Resistance Index from Oral Glucose Tolerance Test Predicts Ischemic Stroke Outcomes in Non-Diabetic Patients with Different Estimated Glomerular Filtration Rate Strata. Cerebrovasc Dis. 2018;46(3-4):140-149. (IF=2.2)
79. Jia Y#, Pan Y#, Ren H, Ji N, Lou F*. Effectiveness and safety of high-voltage pulsed radiofrequency to treat patients with primary trigeminal neuralgia: a multicenter, randomized, double-blind, controlled study. Pain physician. 2018; 21:469-481. (IF=2.6)
80. Pan Y, Jing J, Wang Y, Liu L, Wang Y, He Y*. Association of Hemoglobin Glycation Index with Outcomes of Acute Ischemic Stroke in Type 2 Diabetic Patients. Neurol Res. 2018; 40(7):573-580. (IF=1.7)
81. Zhu B#, Pan Y#, Jing J, Meng X, Zhao X, Liu L, Wang D, Johnston SC, Li H, Wang Y*, Wang Z*, Wang Y*. Neutrophil counts, neutrophil ratio and new stroke in minor ischemic stroke or TIA. Neurology. 2018; 90(21):e1870-e1878. (IF=7.7)
82. Pan Y, Jing J, Chen W, Wang Y, He Y*. Association between impaired renal function and stroke outcome in patients with versus without atrial fibrillation. Eur J Neurol. 2018; 25(8):1041-1048. (IF=4.5)
83. Wu Y#, Zhou Y#, Pan Y#, Zhao X, Li H, Wang D, Johnston SC, Liu L, Wang C, Meng X, Wang Y*, Wang Y*. Impact of CYP2C19 Polymorphism in Prognosis of Minor Stroke or TIA Patients with Declined eGFR on Dual Antiplatelet Therapy: CHANCE substudy. Pharmacogenomics J, 2018; 18(6):713-720. (IF=2.9)
84. Pan Y#, Cai X#, Huo X, Zhao X, Liu L, Wang Y, Miao Z*, Wang Y*. Cost-effectiveness of mechanical thrombectomy within 6 hours of acute ischaemic stroke in China. BMJ Open. 2018;8(2): e018951. (IF=2.4)
85. Pan Y#, Peng Y#, Chen W, Wang Y, Lin Y, He Y*, Wang N*, Wang Y*. THRIVE-c Score Predicts Clinical Outcomes in Chinese Patients after Thrombolysis. Brain Behav. 2018; 8(2): e00927. (IF=2.6)
86. Zhou M#, Pan Y#, Jing J, Wang Y, Zhao X, Liu L, Li H, Wang Y*. Association between β-cell function estimated by HOMA-β and prognosis of non-diabetic patients with ischaemic stroke. Eur J Neurol. 2018;25(3): 549-555. (IF=4.5)
87. Pan Y#, Cai X#, Jing J, Meng X, Li H, Wang Y, Zhao X, Liu L, Wang D, Johnston SC, Wei T, Wang Y*. Stress Hyperglycemia and Prognosis of Minor Ischemic Stroke and Transient Ischemic Attack: The CHANCE Study (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events). Stroke. 2017; 48(11):3006-3011. (IF=7.8)
88. Liu M#, Pan Y#, Zhou L*, Wang Y*. Predictors of post-thrombolysis symptomatic intracranial hemorrhage in Chinese patients with acute ischemic stroke. PLoS One. 2017;12(9):e0184646. (IF=2.9)
89. Pan Y#, Chen W#, Jing J, Zheng H, Jia Q, Li H, Zhao X, Liu L, Wang Y, He Y, Wang Y*. Pancreatic beta cell function and prognosis of nondiabetic patients with ischemic stroke. Stroke. 2017; 48(11):2999-3005. (IF=7.8)
90. Song T#, Pan Y#, Chen R#, Li H, Zhao X, Liu L, Wang C, Wang Y*, Wang Y*. Is there a correlation between socioeconomic disparity and functional outcome after acute ischemic stroke? PLoS One. 2017; 12(7):e0181196. (IF=2.9)
91. Wang H#, Pan Y#, Wang C, Liao X, Wang D, Zhao X, Liu L, Li H, Wang Y*, Wang Y*. Validation of the mSOAR and SOAR Scores to Predict Early Mortality in Chinese Acute Stroke Patients. PLoS One. 2017;12(7):e0180444. (IF=2.9)
92. Chen W#, Pan Y#, Zhao X, Liu L, Li H, Liao X, Wang C, Wang Y*, Wang Y*. Intravenous thrombolysis in Chinese patients with different subtype of mild stroke. Sci Rep. 2017; 7(1):2299. (IF=3.8)
93. Pan Y#, Jing J#, Chen W, Meng X, Li H, Zhao X, Liu L, Wang D, Johnston SC, Wang Y*, Wang Y*. Risks and benefits of clopidogrel-aspirin in minor stroke or TIA: time course analysis of CHANCE. Neurology. 2017; 88(20):1906-1911. (IF=7.7)
94. Jing J#, Pan Y#, Zhao X, Zheng H, Jia Q, Mi D, Chen W, Li H, Liu L, Wang C, He Y, Wang D, Wang Y*, Wang Y*. Insulin Resistance and Prognosis of Nondiabetic Patients With Ischemic Stroke The ACROSS-China Study (Abnormal Glucose Regulation in Patients With Acute Stroke Across China). Stroke. 2017; 48(4):887-893. (IF=7.8)
95. Pan Y#, Jing J#, Chen W, Zheng H, Jia Q, Mi D, Li H, Zhao X, Liu L, Wang C, Gaisano HY, He Y*, Wang Y*, Wang Y*. Post-glucose load measures of insulin resistance and prognosis of nondiabetic patients with ischemic stroke. J Am Heart Assoc. 2017;6(1):e004990. (IF=5.0)
96. Pan Y#, Meng X#, Jing J, Li H, Zhao X, Liu L, Wang D, Johnston SC, Wang Y*, Wang Y*. Association of multiple infarctions and ICAS with outcomes of minor stroke and TIA. Neurology. 2017; 88(11):1081-1088. (IF=7.7)
97. Pan Y#, Chen W#, Xu Y, Yi X, Han Y, Yang Q, Li X, Huang L, Johnston SC, Zhao X, Liu L, Zhang Q, Wang G, Wang Y*, Wang Y*. Genetic polymorphisms and clopidogrel efficacy for acute ischemic stroke or transient ischemic attack: a systematic review and meta-analysis. Circulation. 2017; 135(1):21-33. (IF=35.5)
98. Sun S#, Pan Y#, Zhao X, Liu L, Li H, He Y, Guo L*, Wang Y*, Wang Y*. The association between impaired glucose regulation and prognosis of Chinese patients with intracerebral hemorrhage. Sci Rep. 2016; 6:36220. (IF=3.8)
99. Zhou Y#, Pan Y#, Wu Y#, Zhao X, Li H, Wang D, Johnston SC, Liu L, Wang C, Meng X, Wang Y*, Wang Y*. Effect of Estimated Glomerular Filtration Rate Decline on the Efficacy and Safety of Clopidogrel With Aspirin in Minor Stroke or Transient Ischemic Attack: CHANCE Substudy (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events). Stroke. 2016; 47(11):2791-2796. (IF=7.8)
100. Pan Y#, Chen R*, Li Z, Li H, Zhao X, Liu L, Wang C, Wang Y*, Wang Y*. Socioeconomic status and the quality of acute stroke care: the China National Stroke Registry. Stroke. 2016; 47(11):2836-2842. (IF=7.8)
101. Sun S#, Pan Y#, Zhao X, Liu L, Li H, He Y, Wang Y*, Wang Y*, Guo L*. Prognostic value of admission blood glucose in diabetic and non-diabetic patients with intracerebral hemorrhage. Sci Rep. 2016; 6:32342. (IF=3.8)
102. Pan Y#, Jing J, Li H, Wang Y, Wang Y*, He Y*. Abnormal glucose regulation increases stroke risk in minor ischemic stroke or TIA. Neurology. 2016; 87(15):1551-1556. (IF=7.7)
103. Jing J#, Pan Y#, Zhao X, Zheng H, Jia Q, Li H, Guan L, Liu L, Wang C, Meng X, He Y, Wang Y*, Wang Y*. Prognosis of ischemic stroke with newly diagnosed diabetes according to hemoglobin A1c criteria in Chinese population. Stroke. 2016;47(8):2038-2044. (IF=7.8)
104. Pan Y#, Wang Y, Li H, Gaisano HY, Wang Y*, He Y*. Association of diabetes and prognosis of minor stroke and its subtypes: a prospective observational study. PLoS One. 2016;11(4):e0153178. (IF=2.9)
105. Pan Y#, Song T#, Chen R*, Li H, Zhao X, Liu L, Wang C, Wang Y*, Wang Y*. Socioeconomic deprivation and mortality in people after ischemic stroke: the China National Stroke Registry. Int J Stroke. 2016;11(5):557-564. (IF= 6.3)
106. Pan Y, Zhao X, Jiang Y, Li H, Wang L, Liu L, Wang C, Jing J, Xu J, Meng X, Zhang M, Li Y, Zhou Y, Zhao W, Wang Y*, Wang Y*. Prevalence, awareness and control of hypertension in patients with transient ischemic attacks in China. Neuroepidemiology. 2016;46(2):84-87. (IF=3.2)
107. Wang Y#, Pan Y#, Zhao X, Li H, Wang D, Johnston SC, Liu L, Meng X, Wang A, Wang C, Wang Y*. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack (CHANCE): 1-year outcomes. Circulation. 2015;132(1):40-46. (IF=35.5)
108. Chen W#, Pan Y#, Zhao X, Liao X, Liu L, Wang C, Wang Y*, Wang Y*. Totaled Health Risks in Vascular Events score predicts clinical outcome and symptomatic intracranial hemorrhage in Chinese patients after thrombolysis. Stroke. 2015;46(3):864-866. (IF=7.8)
109. Pan Y#, Chen Q#, Liao X, Zhao X, Wang C, Liu G, Liu L, Wang C, Wang D, Wang Y*, Wang Y*. Preexisting dual antiplatelet treatment increases the risk of post-thrombolysis intracranial hemorrhage in Chinese stroke patients. Neurol Res. 2015;37(1):64-68. (IF=1.7)
110. Wang YL#, Pan YS#, Zhao XQ, Wang D, Johnston SC, Liu LP, Meng X, Wang AX, Wang CX, Wang YJ*. Recurrent stroke was associated with poor quality of life in patients with TIA or minor stroke: finding from the CHANCE trial. CNS Neurosci Ther. 2014; 20(12):1029-1035. (IF=4.8)
111. Pan Y#, Chen Q#, Zhao X, Liao X, Wang C, Du W, Liu G, Liu L, Wang C, Wang Y*, Wang Y*. Cost-effectiveness of thrombolysis within 4.5 hours of acute ischemic stroke in China. PLoS One. 2014;9(10):e110525. (IF=2.9)
112. Pan Y, Jing J, Zhang R, Zhao X, Liu L, Wang H, Liu G, Wang C, Wang Y*, Wang Y*. Poor performance of stroke prognostication using Age and National Institutes of Health Stroke Scale-100 to predict 3- and 12-month outcomes of ischemic stroke in China National Stroke Registry. J Stroke Cerebrovasc Dis. 2014;23(9):2335-2340. (IF=2.0)
113. Pan Y#, Wang A#, Liu G, Zhao X, Meng X, Zhoa K, Liu L, Wang C, Johnston C, Wang Y*, Wang Y*. Cost–effectiveness of clopidogrel-aspirin versus aspirin alone for acute TIA and minor stroke. J Am Heart Assoc. 2014;3(3):e000912. (IF=5.0)
114.Pan YS#, Jing J#, Wang YL, Zhao XQ, Song B, Wang WJ, Wang D, Liu GF, Liu LP, Wang CX, Wang YJ*. Use of statin during hospitalization improves the outcome after intracerebral hemorrhage. CNS Neurosci Ther. 2014; 20(6):548–555. (IF=4.8)
代表性成果:
1. “脑血管病医疗质量改进关键技术与体系的建立和应用”2020年获国家科学技术进步奖二等奖(排名第8)(编号:2020-J-233-2-07-R08) 授予机构:国务院
2. “灌注CT指导下的缺血性脑卒中的动脉溶栓取栓治疗”2019年获浙江省科学技术进步奖三等奖 (排名第3)(编号:2019-J-3-078-R03) 授予机构:浙江省人民政府
首都医科大学建校于1960年,是北京市重点高等院校,著名泌尿外科专家、中国科学院院士、中国工程院院士、原全国人大常委会副委员长吴阶平教授为首任院长。学校由校本部和附属医院(即临床医学院)组成。校本部设有基础医学院、生物医学工程学院、公共卫生与家庭医学学院、高等职业教育学院、中医药学院、顺义校区、继续教育学院、护理学院、卫生事业管理与发展学院及首都医科大学国际教学部;附属医院包括宣武医院(第一临床医学院)、附属北京友谊医院(第二临床医学院)、附属北京朝阳医院(第三临床医学院)、附属北京同仁医院(第四临床医学院)、附属北京天坛医院(第五临床医学院)、附属北京安贞医院(第六临床医学院)、附属北京口腔医院(口腔医学院)、附属北京儿童医院(儿科医学院)、附属北京妇产医院(妇产医学院)、附属北京安定医院(精神卫生学院)、附属复兴医院(第八临床医学院)、附属北京中医医院(中医药临床医学院)和康复医学院。
学校和附属医院现有教职员工和医护人员22575人。有院士4人,正高职称700余人,副高职称1800余人。学校学科专业齐全,学科力量雄厚,在基础和临床各专业拥有一大批具有很高造诣的专家学者,现有3个国家级重点学科,有38个博士学位授予权学科,58个硕士学位授予权学科和2个博士后科研流动站。
校本部和附属医院总占地面积97.3万平方米,总建筑面积134万平方米 ,固定资产总值近46.5亿元,图书馆藏书108.3万册 ,住院病床10039张。学校开办的七年制专业中设有临床医学和口腔医学;五年制专业中设有临床医学、口腔医学、预防医学、护理学、中医学等;四年制专业中设有生物医学工程、中药学和康复治疗学。在临床医学专业中设有儿科医学、康复医学、医学影像、精神卫生与精神病学和医学检验5个专业方向;在生物医学工程专业中设有医学影像设备与技术和听力学专业方向。高等职业教育设有护理、医学检验、药学、医学影像技术、康复技术、口腔修复工艺、眼科验光、实验动物技术、中医学、中药制剂、医学信息、临床医学、预防医学、中药经营贸易和中医学美容专业方向15个专业。首都医科大学现已成为以培养高层次本科生与研究生为核心、以临床应用型人才为主和培养预防、康复、生物医学工程和医学基础各学科、各层次人才,位于全国先进医学院校行列的高等学府。
学校具有较强的学术发展与科研实力,在校本部和附属医院建有一批国家级和市级重点学科和重点实验室,建有高水平的国家级或市级研究和培训机构,如卫生部全科医学培训中心、临床医学研究所、基础医学研究所、神经科学研究所、眼科研究所、老年病医疗研究中心、泌尿外科研究所、心肺血管医疗研究中心、生命科学院、卫生毒理检测中心、生物工程技术研究中心、祖国医学研究所、临床疾病研究中心、中医肝病临床研究中心、生殖医学研究所、心血管疾病临床试验及社区干预中心和北京市卫生政策与卫生经济研究中心等。神经生物学、细胞生物学、电生理学、基础免疫学、实验寄生虫学、医学图像处理、生物医学、信息检测与处理、神经内科、神经外科、心脏内外科、肾移植、呼吸和消化内科、口腔颌面外科、眼科、耳鼻咽喉科、小儿血液病等领域在国内外享有较高声誉,很多学科的研究和医疗水平已经达到或接近国际先进水平。
学校十分重视对外交流与合作,改革开放以来,先后与世界20多个国家和地区签定了友好交流协议, 近十年中,先后接待美国、加拿大、英国、澳大利亚、法国、瑞典、日本、荷兰、意大利、德国、丹麦及台湾、香港和澳门等50多个国家和地区的专家学者8000余人次来校进行学术交流和参观访问。同时,学校积极选送教师、科研人员和管理干部出国进修、参加学术会议和考察访问。