1.2024.06-2025.05，国家重点研发计划“新型冠状病毒感染后认知障碍的临床研究”项目-“社区成年人长新冠感染对认知功能的影响研究”课题，主持。

2.2024.1-2026.12，北京市高层次公共卫生技术人才（学科带头人），“脑血管病防治干预的卫生经济学评价研究”课题，主持。

3.2022.12-2025.12，国家重点研发计划“老年血管疾病整体化防控模式与技术研究”项目-“老年血管疾病医护在线培训系统和示范区建设”课题，主持。

4. 2022.1-2023.12，首都医科大学优秀青年人才项目，“缺血性脑血管病精准抗血小板治疗策略”，主持。

5. 2020.1-2023.12，国家自然科学基金面上项目“胰岛素抵抗对缺血性卒中预后的影响及其慢性炎症机制研究”，主持。

6. 2020.1-2021.12，入选北京市医院管理中心2019年度（第五批）“青苗”计划“胰岛素抵抗与颅颈动脉狭窄斑块的相关性及其机制研究”, 主持。

7. 2018.8-2020.12，“十三五”国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项，“重大慢病流行病学监测大数据平台构建和关键技术研究” ，参与单位负责人。

代表性论文:

1.        Zhou Q#, Gao Y, Chen W, Johnston SC, Amarenco P,Bath PM, Wang X, Yan H, Wang T, Yang Y, Zhang Y, Yang Q, Wang M, Jing J, WangC, Wang Y, Wang Y*, Pan Y*. Efficacy andSafety of Dual Antiplatelet Treatment up to 72 Hours in Acute Ischemic StrokeStratified by Glycemic Status. AnnNeurol. 2025; (inpress) (IF=8.1)

2.        Yang Y#, Cai X#, Zhou M, Chen Y, Pi J,Zhao M, Shi Y, Jing J, Chen W, Yan H, Meng X, Wang Y, Pan Y*,Wang Y*. Association of Left Ventricular Function With CerebralSmall Vessel Disease in a Community-Based Population. CNS Neurosci Ther. 2025;31(2):e70226. (IF=4.8)

3.        Zhang R#, Yao D#, Cai X, Zhang Y, YangY, Li S, Jing J, Wang S, Wang Y, Pan Y*, Wang Y*.Prevalence and Risk Factors of Covert Brain Infarction: a Community-basedCross-sectional Study. Int J Stroke.2025; (in press) (IF= 6.3)

4.        Wang M#, Yan H, Zhang Y, Zhou Q, Meng X, Lin J,Jiang Y, Pan Y*, Wang Y*. Acceleratedbiological aging increases the risk of short- and long-term stroke prognosis inpatients with ischemic stroke or TIA. eBioMedicine. 2025; 111:105494.(IF= 9.7)

5.        Zhang Y#, Wang X#, Gao Y, Chen W,Johnston SC, Amarenco P, Bath PM, Yan H, Wang T, Yang Y, Zhou Q, Wang M, JingJ, Wang C, Wang Y, Wang Y*, Pan Y*. DualAntiplatelet Treatment up to 72 Hours After Ischemic Stroke Stratified by RiskProfile: A Post Hoc Analysis. Stroke. 2025;56(1):46-55. (IF=7.8)

6.        Zhang Y#, Pan Y#, Yan H,Meng X, Lin J, Wang M, Li H, Xu Q, Chen P, Wang A, Zhou Y*, Wang Y*.Prognostic Impact of 1-Year Changes in Creatinine- and Cystatin C-BasedEstimated Glomerular Filtration Rate After Stroke on 5-Year Outcomes: InsightsFrom the Third China National Stroke Registry. J Am Heart Assoc. 2025Jan 16:e037579. (IF=5.0)

7.        Zhang Y#, Wang M#, Cai X, Jin A, JingJ, Wang S, Meng X, Li S, Zhou Q, Wang X, Wei T, Wang Y, Pan Y*.Associations of non-insulin-based insulin resistanceindices with presence and extent of multi-territorial atherosclerosis: Across-sectional study. J Clin Lipidol. 2025; (in press). (IF=3.6)

8.        Zhou Q#, Zhu W#, Cai X, Jing J, Wang M,Wang S, Jin A, Meng X, Wei T, Wang Y, Pan Y*. Obesityand brain volumes: mediation by cardiometabolic and inflammatory measures. StrokeVasc Neurol. 2025; (inpress). (IF=4.4)

9.        Zhou Q, Cai X, Jin A, Jing J, Wang M, Wang S, Mei L, Meng X,Shan L, Wei T, Wang Y, Liu L*, Pan Y*.Associations between adipose tissue-specific insulin resistance andatherosclerotic plaques and burden in community-based population. Neuroepidemiology. 2025;(in press).  (IF=3.2)

10.    Wang D#, Pan Y#, Cai X#,Jing J, Yan H, Wang S, Meng X, Mei L, Zhang Y, Li S, Wei T, Zhou Y*,Wang Y*. Prevalence and Associated Factors of Atherosclerotic Plaqueand Stenosis in Renal Arteries: A Community-Based Study. Angiology. 2025;(in press). (IF=2.6)

11.    Liu Y#, Zhao J#, Gao Y, Chen W,Johnston SC, Bath PM, Amarenco P, Yan H, Wang X, Yang Y, Wang T, Wang Y, PanY*, Wang Y*. Clopidogrel and Aspirin InitiatedBetween 24 to 72 Hours for Mild Ischemic Stroke: A Subgroup Analysis of theINSPIRES Randomized Clinical Trial. JAMANetw Open. 2024;7(9):e2431938. (IF=10.5)

12.    Guan L#, Han S, Johnston SC, Bath PM, Amarenco P,Yang Y, Wang T, Jing J, Wang C, Gao Y, Chen W, Yan H, Wang X, Wang Y, Wang Y, PanY*. Duration of Benefit and Risk of Dual AntiplateletTherapy up to 72 Hours After Mild Ischemic Stroke and Transient IschemicAttack. Neurology. 2024; 103(7):e209845. (IF=7.7)

13.    Liu D#, Zhang Y#, Cai X, Yang Y, WangS, Mei L, Jing J, Li S, Wang M, Meng X, Wei T, Wang Y, Wang Y*, PanY*. Associations of 10-year atherosclerotic cardiovasculardisease risk scores with cerebral small vessel disease: the PolyvasculaREvaluation for Cognitive Impairment and vaScular Events (PRECISE) study. AgeAgeing. 2024;53(7):afae161. (IF= 6.0)

14.    Zhou M#, Zhou Y#, Jing J, Wang M, JinA, Cai X, Meng X, Liu T, Wang Y, Wang Y*, Pan Y*. Insulin Resistance and White Matter Microstructural Abnormalities inNondiabetic Adult: A Population-Based Study. Int J Stroke. 2024;19(10):1162-1171. (IF= 6.3)

15.    Zhang Y#, Liu D#, Cai X, Jin A, Mei L,Jing J, Wang S, Meng X, Li S, Wang M, Yan H, Wei T, Wang Y*, PanY*. Associations of life's essential 8 with extent ofmulti-territorial atherosclerotic plaques and stenosis: a cross-sectionalstudy. BMC Geriatr. 2024;24(1):503. (IF=3.4)

16.    Zhou M#, Mei L#, Jing J, Yang Y, Cai X,Meng X, Jin A, Lin J, Li S, Li H, Wei T, Wang Y, Wang Y*, PanY*. Blood Pressure Partially Mediated the Association ofInsulin Resistance and Cerebral Small Vessel Disease: A Community-Based Study. J Am Heart Assoc. 2024; 13(5):e031723.(IF=5.0)

17.    Meng Y#, Wang S#, Zhu W, Wang T, Liu D,Wang M, Pi J, Liu Y, Zhuo Z, Pan Y*, Wang Y*.Association of Mean Upper Cervical Spinal Cord Cross-Sectional Area WithCerebral Small Vessel Disease: A Community-Based Cohort Study. Stroke. 2024; 55(3):687-695. (IF=7.8)

18.    Liu D#, Cai X, Yang Y, Wang S, Mei L, Jing J, LiS, Wang M, Chen Y, Meng X, Wei T, Wang Y, Wang Y*, Pan Y*.Association between Life's Essential 8 and Cerebral Small Vessel Disease. StrokeVasc Neurol. 2024; 9(5):481-489. (IF=4.4)

19.    Pan Y#, Huo X, Jin A, Nguyen TN, Ma G, Tong X, Zhang X, Gao F, MaN, Mo D, Ren Z, Wang Y, Miao Z*. Cost-effectiveness of endovasculartherapy for acute ischemic stroke with large infarct in China. J NeurointervSurg. 2024; 16(5):453-458. (IF=4.5)

20.    Yang Y#, Cai X#, Zhou M, Chen Y, Pi J,Zhao M, Shi Y, Wang S, Jing J, Chen W, Meng X, Wang Y, Pan Y*,Wang Y*. Prevalence and Risk Factors of Cerebral Small VesselDisease from a Population-Based Cohort in China. Neuroepidemiology. 2023; 57(6):413-422. (IF=3.2)

21.    Zhang Y#, Xia Z#, Cai X, Su X, Jin A,Mei L, Jing J, Wang S, Meng X, Li S, Wang M, Wei T, Wang Y*, He Y*,Pan Y*. Association of metabolicdysfunction-associated fatty liver disease with systemic atherosclerosis: acommunity-based cross-sectional study. Cardiovasc Diabetol. 2023;22(1):342. (IF=8.5)

22.    Zhou Q#, Yan H, Jin A, Meng X, Lin J, Li H, WangY, Pan Y*. Adipose tissue specific insulin resistanceand prognosis of nondiabetic patients with ischemic stroke. Diabetol MetabSyndr. 2023;15(1):246. (IF=3.4)

23.    Cai X#, Sun J#, Jin A, Jing J, Wang S,Mei L, Meng X, Li S, Wei T, Wang Y, Pan Y*.Association of insulin resistance with intra- and extra-cranial atheroscleroticburden in the nondiabetic community population. Neurobiol Dis. 2023;186:106268.(IF=5.1)

24.    Wang Y#, Cai X#, Li H, Jin A, Jiang L,Chen W, Jing J, Mei L, Li S, Meng X, Wei T, Wang Y, Pan Y*,Wang Y*. Association of Intracranial Atherosclerosis with CerebralSmall Vessel Disease in Community-based Population. Eur J Neurol. 2023;30(9):2700–2712. (IF=4.5)

25.    Zhang Y#, Pan Y#, Cai X#,Jing J, Yan H, Wang S, Meng X, Mei L, Zhang Y, Li S, Wei T, Zhou Y*,Wang Y*. Association between Urine Albumin-to-creatinine Ratio andIntracranial Atherosclerotic Plaque in Chinese Adults - Results from thePRECISE Study. J Atheroscler Thromb. 2023;30(12):1828-1837. (IF=3.0)

26.    Tian Y#, Cai X#, Zhou Y, Jin A, Wang S,Yang Y, Mei L, Jing J, Li S, Meng X, Wei T, Liu T, Wang Y, Pan Y*,Wang Y*. Impaired glymphatic system as evidenced by low diffusivityalong perivascular spaces is associated with cerebral small vessel disease: apopulation-based study. Stroke Vasc Neurol. 2023;8(5):413-423. (IF=4.4)

27.    Zhou H#, Chen W, Suo Y, Meng X, Zhao X, Wang M,Liu L, Li H, Pan Y*, Wang Y*. ExternalValidation of the Nelson Equation for Kidney Function Decline in Patients withAcute Ischemic Stroke or Transient Ischemic Attack. Clin Interv Aging.2023; 18: 901-909. (IF=3.5)

28.    Pan Y#, Shen J#, Cai X#, Chen H, Zong G, ZhuW, Jing J, Liu T, Jin A, Wang Y, Meng X, Yuan C*, Wang Y*.Adherence to a healthy lifestyle and brain structural imaging markers. Eur J Epidemiol. 2023;38(6):657-668. (IF= 7.7)

29.    Pan Y#, Meng X#, Yuan B, Johnston SC, Li H, Bath PM,Dong Q, Xu A, Jing J, Lin J, Jiang Y, Xie X, Jin A, Suo Y, Yang H, Feng Y, ZhouY, Liu Q, Li X, Liu B, Zhu H, Zhao J, Huang X, Li H, Xiong Y, Li Z, Wang Y,Zhao X, Liu L, Wang Y*; INSURE Investigators. Indobufen versusaspirin in patients with acute ischaemic stroke in China (INSURE): arandomised, double-blind, double-dummy, active control, non-inferiority trial. Lancet Neurol. 2023; 22(6):485-493. (IF=46.5)

30.    Fang H#, Chen W#, Jin A,Wang M, Yan H, Xiang X, Pan Y*. Effects of geneticallydetermined mineral status on life expectancy: a Mendelian randomization study. ChinMed J (Engl). 2023;136(2):242-244. (IF=7.5)

31.    Tian Y#, Li S#, Yang Y,Cai X, Jing J, Wang S, Meng X, Mei L, Jin A, Yao D, Wei T, Wang Y, Pan Y*,Wang Y*. Associations of deep medullary veins with vascular riskfactors, laboratory indicators, and cerebral small vessel disease: Apopulation-based study. Brain Behav.2023;13(5): e2974. (IF=2.6)

32.    Jin A#, Wang S#, Li J,Wang M, Lin J, Li H, Meng X, Wang Y, Pan Y*. Mediationof systemic inflammation on insulin resistance and prognosis of nondiabeticpatients with ischemic stroke. Stroke.2023; 54(3):759-769. (IF=7.8)

33.    Zhou M#, Wang S#,Jing J, Yang Y, Cai X, Meng X, Mei L, Lin J, Li S, Li H, Wei T, Wang Y, PanY*, Wang Y*. Insulin resistance based on postglucose load measure isassociated with prevalence and burden of cerebral small vessel disease. BMJOpen Diabetes Res Care. 2022;10(5):e002897. (IF=3.7)

34.    Wang M#, Mei L#,Jin A, Cai X, Jing J, Wang S, Meng X, Li S, Wei T, Wang Y, Pan Y*.Association between TriglycerideGlucose index and Atherosclerotic Plaques and Burden: Findings from aCommunity-Based Study. Cardiovasc Diabetol. 2022;21(1):204. (IF=8.5)

35.    Xu Y#, Chen W#, Jiang L,Wang Y, Zhao X, Liu L, Yao D, Guo L, Wang Y, Pan Y*,Wang Y*. Aspirin platelet reactivity on platelet function andclinical outcome in minor stroke or transient ischemic attack. J StrokeCerebrovasc Dis. 2022;31(9):106683. (IF=2.0)

36.    Zhang Y, Jin A, Meng X, Wang M, Li H, Pan Y*,Wang Y*. Association between Diabetes Duration and 1-Year Prognosisof Stroke: A National Registry Study. Brain Behav.2022; 12(9): e2725. (IF=2.6)

37.    Pan Y#, Cai X#, Jing J, Wang S, Meng X, Mei L, Yang Y,Jin A, Yao D, Li S, Li H, Wei T, Wang Y*, Wang Y*. Differential Associations of Lipoprotein(a) Level with CerebralLarge Artery and Small Vessel Diseases. Stroke Vasc Neurol. 2022;7:e001625. (IF=4.4)

38.    Liu D#, Cai X#, Yang Y, Wang S, Yao D,Mei L, Jing J, Li S, Yan H, Meng X, Li H, Wei T, Wang Y, Pan Y*,Wang Y*. Associations of Life's Simple 7 with Cerebral Small VesselDisease. Stroke. 2022;53(9):2859-2867.(IF=7.8)

39.    Jing J#, Zhou Y#, Pan Y#,Cai X#, Zhu W, Zhang Z, Li Z, Liu C, Meng X, Cheng J, Wang Y, Li H,Wu Z, Wang S, Niu H, Wen W, Liu T*, Wei T*, Wang Y*,Sachdev PS. Reduced White Matter Microstructural Integrity in Prediabetes andDiabetes: A Population-based Study. eBioMedicine. 2022; 82:104144. (IF=9.7)

40.    Jin A#, WangM#, Chen W, Yan H, Xiang X, Pan Y*. DifferentialEffects of Genetically Determined Cholesterol Efflux Capacity on CoronaryArtery Disease and Ischemic Stroke. Front Cardiovasc Med. 2022; 9:891148.(IF=2.8)

41.     Pan Y#, Jing J#,Cai X#, Jin Z, Wang S, Wang Y, Zeng C, Meng X, Ji J, Li L, Lyu L, ZhangZ, Mei L, Li H, Li S, Wei T*, Wang Y*. Prevalence andVascular Distribution of Multiterritorial Atherosclerosis AmongCommunity-Dwelling Adults in Southeast China. JAMA Netw Open. 2022; 5(6):e2218307. (IF=10.5)

42.     Yao D#, Li S#,Jing J, Cai X, Jin A, Yang Y, Wang S, Meng X, Lin J, Mei L, Li H, Wei T, Wang Y,Pan Y*, Wang Y*. Association of serumcystatin C with cerebral small vessel disease in community-based population. Stroke. 2022;53(10):3123-3132. (IF=7.8)

43.    Jiang L#, CaiX#, Yang Y, Wang S, Jing J, Mei L, Jin A, Li S, Meng X, Li H, Wei T,Wang Y, Pan Y*, Wang Y*. Association ofinflammatory markers with cerebral small vessel disease in community-basedpopulation. J Neuroinflammation.2022;19(1):106. (IF=9.3)

44.   Ma G#, Yu Z#,Jia B, Xian Y, Ren Z, Mo D, Ma N, Gao F, Tong X, Shi X, Li L, Pan Y*,Miao Z*; ANGEL-ACT study group. Time to Endovascular Reperfusion andOutcome in Acute Ischemic Stroke: A Nationwide Prospective Registry inChina. Clin Neuroradiol. 2022;32(4):997-1009. (IF=2.4)

45.    Pan Y, Meng X, Jin A, Johnston SC, Li H, BathPM, Xie X, Jing J, Lin J, Wang Y, Zhao X, Li Z, Jiang Y, Liu L, Yang H, ChengJ, Wang Z, Wang Y*. Time course for benefit and risk ofticagrelor and aspirin in CYP2C19 loss-of-function carriers with acute ischemicstroke or transient ischemic attack: a secondary analysis from the CHANCE-2randomized trial. JAMA Neurol.2022;79(8):739-745.(IF=20.4)

46.    Pan Y#, Meng X#,Chen W, Jing J, Lin J, Jiang Y, Johnston SC, Bath PM, Dong Q, Xu A, Li H, Wang Y*. Indobufenversus aspirin in acute ischaemic stroke (INSURE): rationale and design of amulticentre randomised trial. Stroke Vasc Neurol. 2022;7: e001480. (IF=4.4)

47.    Wang Y*#, Pan Y#, Li H, Amarenco P, Denison H, Evans SR, HimmelmannA, James S, Knutsson M, Ladenvall P, Molina CA, Johnston SC*. Timecourse for benefit and risk of ticagrelor and aspirin in acute ischemic strokeor transient ischemic attack. Neurology. 2022; 99(1):e46-e54. (IF=7.7)

48.    Pan Y#, Wangqin R#,Li H, Jin A, Li J, Lin J, Meng X, Xian Y, Laskowitz DT, Wang Y*.LDL-C Levels, Lipid Lowering Treatment and Recurrent Stroke in Minor IschaemicStroke or TIA. Stroke Vasc Neurol. 2022; 7: e001317. (IF=4.4)

49.    Chen W#, YaoD#, Yan H, Wang M, Pan Y*. GeneticallyPredicted Childhood Obesity and Adult Atrial Fibrillation: a MendelianRandomization Study. Nutr Metab Cardiovasc Dis. 2022; 32(4):1019-1026. (IF=3.3)

50.   Zhou M, Li H, Wang Y, Pan Y*, Wang Y*.Causal effect of Insulin Resistance on Small Vessel Stroke and Alzheimer'sDisease: A Mendelian Randomization Analysis. Eur J Neurol. 2022;29(3):698-706.(IF=4.5)

51.   Wang D#,Pan Y#, Li H, Yan H, MengX, Lin J, Wang H, Matsushita H, Shlipak MG, Zhou Y*, Wang Y*. The Associationbetween Baseline and 3-Month Albuminuria and 1-Year Prognosis of IschemicStroke. Cerebrovasc Dis. 2022;51(1):67-74.(IF=2.2)

52.   Chen W#, Cai X#, Yan H, Pan Y*.Causal Effect of Obstructive Sleep Apnea on Atrial Fibrillation: A MendelianRandomization Study. J Am Heart Assoc.2021;10(23):e022560. (IF=5.0)

53.   Wang Y*#, PanY#, Li H,Amarenco P, Denison H, Evans SR, Himmelmann A, James S, Birve F, Ladenvall P,Molina CA, Johnston SC*; THALES Investigators. Efficacy and safetyof ticagrelor and aspirin in patients with moderate ischemic stroke: anexploratory analysis of the THALES randomized clinical trial. JAMA Neurol. 2021;78(9):1091-1098. (IF=20.4)

54.   Xiong Y#,Pan Y#, Nogueira RG, Ren Z, Jovin TG, Wang Y*.Treating acute large vessel occlusion stroke: to bridge or not to bridge? StrokeVasc Neurol. 2021; 6(3):324-327. (IF=4.4)

55.   Pan Y#, Li Z, Li J, Jin A, Lin J, Jing J, Li H, Meng X, WangY, Wang Y*. Residual risk and its risk factors for ischemic strokewith adherence to guideline-based secondary stroke prevention. J Stroke. 2021;23(1):51-60. (IF=6.0)

56.   Pan Y#, Jing J#, Cai X#, Wang Y, Wang S, Meng X, ZengC, Shi J, Ji J, Lin J, Lyu L, Zhang Z, Mei L, Li S, LiS, Zhu W, Li H, Wei T*, Wang Y*. PolyvasculaREvaluation for Cognitive Impairment and vaScular Events (PRECISE)- apopulation-based prospective cohort study: rationale, design and baselineparticipant characteristics. Stroke Vasc Neurol. 2021;6(1):145-151. (IF=4.4)

57.   Pan Y#, Wangqin R#, Li H, Wang Y, Meng X, Johnston SC, Simon T, Lin J,Zhao X, Liu L, Wang D, Wang Y*. F2R polymorphisms and clopidogrelefficacy and safety in patients with minor stroke or TIA. Neurology. 2021; 96(1):e1-e9. (IF=7.7)

58.   Pan Y, Li H, Wardlaw JM, Wang Y*.A new dawn of preventing dementia by preventing cerebrovascular diseases. BMJ. 2020;371:m3692. (IF=93.6)

59.   Fang HJ#, Pan YS#, Wang YJ, Wang CX,Wang YL, Zhong LY*. Prognostic value of admission hyperglycemia on outcomes ofthrombolysis in ischemic stroke patients with or without diabetes. Chin Med J (Engl). 2020;133(18):2244-2246.(IF=7.5)

60.   Pan Y*, Chen W, Yan H, Wang M,Xiang X. Glycemic Traits and Alzheimer's Disease: A Mendelian RandomizationStudy. Aging (Albany NY). 2020; 12(22): 22688-22699. (IF=3.9)

61.   Chen W#, Wang S#, Lv W, Pan Y*.Causal Associations of Insulin Resistance with Coronary Artery Disease andIschaemic Stroke: A Mendelian Randomisation Analysis. BMJ Open Diabetes Res Care. 2020; 8(1). pii: e001217. (IF=3.7)

62.   Yang Y#,Chen W, Meng X, Liu L, Wang Y, Pan Y*, Wang Y*.Impact of Smoking on Platelet Function of Ticagrelor Versus Clopidogrel inMinor Stroke or Transient Ischaemic Attack. Eur J Neurol. 2020; 27(5):833-840. (IF=4.5)

63.   Jiang J#,Cai X#, Pan Y*,Yan Y, Zhu H, Yang X, Zheng D, Gaisano H, Wei T*, Yan H*.Relationship of obesity to adipose tissue insulin resistance. BMJ OpenDiabetes Res Care. 2020; 8(1). pii: e000741. (IF=3.7)

64.   Pan Y*, Zhang L, Li Z,Meng X, Wang Y, Li H, Liu L, Wang Y*. Cost-Effectiveness of a MultifacetedQuality Improvement Intervention for Acute Ischemic Stroke in China. Stroke. 2020;51(4):1265-1271. (IF=7.8)

65.   Wen J#, Cai X#, Zhang J, Jiang J, Li W,Liu G, Wang M, Gaisano HY, Pan Y*, He Y*.Relation of adipose tissue insulin resistance to prediabetes. Endocrine. 2020; 68(1):93-102. (IF= 3.0)

66.   Lin J#, Wang Y, Wang Y, Pan Y*.Inflammatory biomarkers and risk of ischemic stroke and subtypes: A 2-sampleMendelian randomization study. Neurol Res. 2020;42(2):118-125. (IF=1.7)

67.   Liu H#, Zheng H#, Wu P, Liu CF, Wang D,Li H, Meng X, Wang Y, Cao Y, Wang Y, Pan Y*. Estimatedglomerular filtration rate, anemia and outcomes in patients with ischemicstroke. Ann Transl Med. 2020;8(1):2. (IF=3.6)

68.   Pan Y*, Wang Y, Wang Y. Investigationof Causal Effect of Atrial Fibrillation on Alzheimer's Disease: A MendelianRandomization Study. J Am HeartAssoc.2020;9(2):e014889. (IF=5.0)

69.   Liu H#,Meng X#, Liu CF, Wang D,Zheng H, Li H, Liu L, Wang Y, Wang Y, Pan Y*. HigherHemoglobin A1c Level Is Associated with Poor Outcome of IntracerebralHemorrhage. Front Neurol. 2019; 10:1073.(IF=2.7)

70.   Pan Y*, Li H, Wang Y, Meng X,Wang Y*. Causal Effect of Lp(a) [Lipoprotein(a)] Level on IschemicStroke and Alzheimer Disease: A Mendelian Randomization Study. Stroke. 2019;50(12):3532-3539. (IF=7.8)

71.   Zhu B#, Pan Y*, Jing J, Meng X, ZhaoX, Liu L, Wang Y, Wang Y, Wang Z*. Stress Hyperglycemia and Outcome ofNon-diabetic Patients After Acute Ischemic Stroke. Front Neurol. 2019; 10:1003. (IF=2.7)

72.   Pan Y#, Elm JJ#, LiH, Easton JD, Wang Y, Farrant M, Meng X, Kim AS, Zhao X, Meurer WJ, Liu L,Dietrich D, Wang Y*, Johnston SC*. Outcomes AssociatedWith Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack: APooled Analysis of Clopidogrel in High-Risk Patients With Acute Non-DisablingCerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA andMinor Ischemic Stroke (POINT) Trials. JAMANeurol. 2019;76(12):1466-1473. (IF=20.4)

73.   Wang T#, PanY#, Lin J, Anand R, Wang D, Johnston SC, Meng X, Li H, ZhaoX, Liu L, Wang Y, Wang Y*; CHANCE investigators. Influence ofsmoking on CYP2C19 genetic variants and clopidogrel efficacy in patients withminor stroke or TIA. Eur J Neurol. 2019;26(9):1175-1182.(IF=4.5)

74.   Sun S#, PanY#, Bai L, Zhao X, Liu L, Li H, Wang Y, Guo L*,Wang Y*. GWTG Risk Model for All Stroke Types Predicts In-Hospitaland 3-Month Mortality in Chinese Patients with Acute Stroke. J Stroke Cerebrovasc Dis. 2019;28(3):800-806. (IF=2.0)

75.   Pan Y, Chen W, Wang Y*.Prediabetes and outcome of ischemic stroke or transient ischemic attack: a systematicreview and meta-analysis. J Stroke Cerebrovasc Dis. 2019; 28(3):683-692. (IF=2.0)

76.   Pan Y, Chen W, Wang Y, Li H, Johnston SC, Simon T, Zhao X, Liu L, Wang D, Meng X,Wang Y*. Association between ABCB1 Polymorphisms and Outcomes of ClopidogrelTreatment in Patients with Minor Stroke or Transient Ischemic Attack: SecondaryAnalysis of a Randomized Clinical Trial. JAMANeurol. 2019;76(5):552-560. (IF=20.4)

77.   Zhu B#, Liu H#, Pan Y#, Jing J, Li H, Zhao X, Liu L, Wang D, JohnstonSC, Wang Z, Wang Y*, Wang Y*. Elevated Neutrophil andPresence of Intracranial Artery Stenosis Increase the Risk of Recurrent Stroke.Stroke. 2018; 49(10): 2294-2300. (IF=7.8)

78.   Zhou Y#, Zhang Y#, Pan Y#, Jing J, Zhao X, Liu L, Wang C, Li H, YanH, Meng X, Wang Y*, Wang Y*. Insulin Resistance Indexfrom Oral Glucose Tolerance Test Predicts Ischemic Stroke Outcomes inNon-Diabetic Patients with Different Estimated Glomerular Filtration RateStrata. Cerebrovasc Dis. 2018;46(3-4):140-149.(IF=2.2)

79.   Jia Y#, PanY#, Ren H, Ji N, Lou F*. Effectiveness and safetyof high-voltage pulsed radiofrequency to treat patients with primary trigeminalneuralgia: a multicenter, randomized, double-blind, controlled study. Pain physician. 2018; 21:469-481. (IF=2.6)

80.   Pan Y, Jing J, Wang Y, Liu L, WangY, He Y*. Association of Hemoglobin Glycation Index with Outcomes ofAcute Ischemic Stroke in Type 2 Diabetic Patients. Neurol Res. 2018; 40(7):573-580. (IF=1.7)

81.   Zhu B#, PanY#, Jing J, Meng X, Zhao X, Liu L, Wang D, Johnston SC, LiH, Wang Y*, Wang Z*, Wang Y*.Neutrophil counts, neutrophil ratio and new stroke in minor ischemic stroke orTIA. Neurology. 2018; 90(21):e1870-e1878.(IF=7.7)

82.   Pan Y, Jing J, Chen W, Wang Y,He Y*. Association between impaired renal function and strokeoutcome in patients with versus without atrial fibrillation. Eur J Neurol. 2018; 25(8):1041-1048. (IF=4.5)

83.   Wu Y#, Zhou Y#, Pan Y#, Zhao X, Li H, Wang D, Johnston SC, Liu L,Wang C, Meng X, Wang Y*, Wang Y*. Impact of CYP2C19 Polymorphismin Prognosis of Minor Stroke or TIA Patients with Declined eGFR on DualAntiplatelet Therapy: CHANCE substudy. PharmacogenomicsJ, 2018; 18(6):713-720. (IF=2.9)

84.   Pan Y#, Cai X#, HuoX, Zhao X, Liu L, Wang Y, Miao Z*, Wang Y*. Cost-effectivenessof mechanical thrombectomy within 6 hours of acute ischaemic stroke in China. BMJ Open. 2018;8(2):e018951. (IF=2.4)

85.   Pan Y#, Peng Y#, ChenW, Wang Y, Lin Y, He Y*, Wang N*, Wang Y*. THRIVE-cScore Predicts Clinical Outcomes in Chinese Patients after Thrombolysis. Brain Behav. 2018; 8(2): e00927. (IF=2.6)

86.   Zhou M#, PanY#, Jing J, Wang Y, Zhao X, Liu L, Li H, Wang Y*.Association between β-cell function estimated by HOMA-β and prognosis of non-diabeticpatients with ischaemic stroke. Eur JNeurol. 2018;25(3): 549-555. (IF=4.5)

87.   Pan Y#, Cai X#, JingJ, Meng X, Li H, Wang Y, Zhao X, Liu L, Wang D, Johnston SC, Wei T, Wang Y*.Stress Hyperglycemia and Prognosis of Minor Ischemic Stroke and TransientIschemic Attack: The CHANCE Study (Clopidogrel in High-Risk Patients With AcuteNondisabling Cerebrovascular Events). Stroke.2017; 48(11):3006-3011. (IF=7.8)

88.   Liu M#, PanY#, Zhou L*, Wang Y*. Predictors ofpost-thrombolysis symptomatic intracranial hemorrhage in Chinese patients withacute ischemic stroke. PLoS One. 2017;12(9):e0184646. (IF=2.9)

89.   Pan Y#, Chen W#, Jing J, Zheng H, Jia Q, Li H, Zhao X, LiuL, Wang Y, He Y, Wang Y*. Pancreatic beta cell function and prognosisof nondiabetic patients with ischemic stroke. Stroke. 2017; 48(11):2999-3005. (IF=7.8)

90.   Song T#, PanY#, Chen R#, Li H, Zhao X, Liu L, Wang C, Wang Y*,Wang Y*. Is there a correlation between socioeconomic disparity andfunctional outcome after acute ischemic stroke? PLoS One. 2017; 12(7):e0181196. (IF=2.9)

91.   Wang H#, Pan Y#, Wang C, Liao X, Wang D, Zhao X, Liu L, Li H, Wang Y*, Wang Y*. Validation of the mSOAR and SOAR Scores to Predict EarlyMortality in Chinese Acute Stroke Patients. PLoS One. 2017;12(7):e0180444. (IF=2.9)

92.     Chen W#, Pan Y#, Zhao X, Liu L,Li H, Liao X, Wang C, Wang Y*, Wang Y*. Intravenous thrombolysisin Chinese patients with different subtype of mild stroke. Sci Rep. 2017; 7(1):2299. (IF=3.8)

93.     Pan Y#, Jing J#, Chen W, Meng X, Li H, Zhao X, Liu L, WangD, Johnston SC, Wang Y*, Wang Y*. Risks and benefits ofclopidogrel-aspirin in minor stroke or TIA: time course analysis of CHANCE. Neurology. 2017; 88(20):1906-1911. (IF=7.7)

94.   Jing J#, PanY#, Zhao X, Zheng H, Jia Q, Mi D, Chen W, Li H, LiuL, Wang C, He Y, Wang D, Wang Y*, Wang Y*. Insulin Resistance andPrognosis of Nondiabetic Patients With Ischemic Stroke The ACROSS-China Study(Abnormal Glucose Regulation in Patients With Acute Stroke Across China). Stroke. 2017; 48(4):887-893.(IF=7.8)

95.   Pan Y#, Jing J#, ChenW, Zheng H, Jia Q, Mi D, Li H, Zhao X, Liu L, Wang C, Gaisano HY, He Y*,Wang Y*, Wang Y*. Post-glucose load measures of insulinresistance and prognosis of nondiabetic patients with ischemic stroke. J Am Heart Assoc. 2017;6(1):e004990. (IF=5.0)

96.   Pan Y#, Meng X#, JingJ, Li H, Zhao X, Liu L, Wang D, Johnston SC, Wang Y*, Wang Y*.Association of multiple infarctions and ICAS with outcomes of minor stroke andTIA. Neurology. 2017; 88(11):1081-1088.(IF=7.7)

97.   Pan Y#, Chen W#, XuY, Yi X, Han Y, Yang Q, Li X, Huang L, Johnston SC, Zhao X, Liu L, Zhang Q,Wang G, Wang Y*, Wang Y*. Genetic polymorphisms andclopidogrel efficacy for acute ischemic stroke or transient ischemic attack: asystematic review and meta-analysis. Circulation.2017; 135(1):21-33. (IF=35.5)

98.   Sun S#, PanY#, Zhao X, Liu L, Li H, He Y, Guo L*, Wang Y*,Wang Y*. The association between impaired glucose regulation and prognosisof Chinese patients with intracerebral hemorrhage. Sci Rep. 2016; 6:36220. (IF=3.8)

99.   Zhou Y#, PanY#, Wu Y#, Zhao X, Li H, Wang D, Johnston SC, LiuL, Wang C, Meng X, Wang Y*, Wang Y*. Effect of EstimatedGlomerular Filtration Rate Decline on the Efficacy and Safety of ClopidogrelWith Aspirin in Minor Stroke or Transient Ischemic Attack: CHANCE Substudy (Clopidogrelin High-Risk Patients With Acute Nondisabling Cerebrovascular Events). Stroke. 2016; 47(11):2791-2796.(IF=7.8)

100.Pan Y#, Chen R*,Li Z, Li H, Zhao X, Liu L, Wang C, Wang Y*, Wang Y*. Socioeconomic status and thequality of acute stroke care: the China National Stroke Registry. Stroke. 2016; 47(11):2836-2842. (IF=7.8)

101.Sun S#, PanY#, Zhao X, Liu L, Li H, He Y, Wang Y*, Wang Y*,Guo L*. Prognostic value of admission blood glucose in diabetic and non-diabeticpatients with intracerebral hemorrhage. Sci Rep. 2016; 6:32342. (IF=3.8)

102.Pan Y#, Jing J, Li H, Wang Y,Wang Y*, He Y*. Abnormal glucose regulation increases strokerisk in minor ischemic stroke or TIA. Neurology.2016; 87(15):1551-1556. (IF=7.7)

103.Jing J#, PanY#, Zhao X, Zheng H, Jia Q, Li H, Guan L, Liu L, Wang C, MengX, He Y, Wang Y*, Wang Y*. Prognosis of ischemic strokewith newly diagnosed diabetes according to hemoglobin A1c criteria in Chinesepopulation. Stroke. 2016;47(8):2038-2044.(IF=7.8)

104.Pan Y#, Wang Y, Li H, GaisanoHY, Wang Y*, He Y*. Association of diabetes and prognosisof minor stroke and its subtypes: a prospective observational study. PLoS One. 2016;11(4):e0153178. (IF=2.9)

105.Pan Y#, Song T#, ChenR*, Li H, Zhao X, Liu L, Wang C, Wang Y*, Wang Y*.Socioeconomic deprivation and mortality in people after ischemic stroke: theChina National Stroke Registry. Int J Stroke. 2016;11(5):557-564. (IF= 6.3)

106.Pan Y, Zhao X, Jiang Y, Li H,Wang L, Liu L, Wang C, Jing J, Xu J, Meng X, Zhang M, Li Y, Zhou Y, Zhao W,Wang Y*, Wang Y*. Prevalence, awareness and control ofhypertension in patients with transient ischemic attacks in China. Neuroepidemiology. 2016;46(2):84-87. (IF=3.2)

107.Wang Y#, PanY#, Zhao X, Li H, Wang D, Johnston SC, Liu L, Meng X, WangA, Wang C, Wang Y*. Clopidogrel with aspirin in acute minor strokeor transient ischemic attack (CHANCE): 1-year outcomes. Circulation. 2015;132(1):40-46. (IF=35.5)

108.Chen W#, Pan Y#, Zhao X, Liao X, Liu L, Wang C, Wang Y*,Wang Y*. Totaled Health Risks in Vascular Events score predicts clinical outcomeand symptomatic intracranial hemorrhage in Chinese patients after thrombolysis.Stroke. 2015;46(3):864-866.(IF=7.8)

109.Pan Y#, Chen Q#,Liao X, Zhao X, Wang C, Liu G, Liu L, Wang C, Wang D, Wang Y*, WangY*. Preexisting dual antiplatelet treatment increases the risk ofpost-thrombolysis intracranial hemorrhage in Chinese stroke patients. Neurol Res. 2015;37(1):64-68.(IF=1.7)

110.Wang YL#, Pan YS#, Zhao XQ,Wang D, Johnston SC, Liu LP, Meng X, Wang AX, Wang CX, Wang YJ*. Recurrent stroke was associatedwith poor quality of life in patients with TIA or minor stroke: finding fromthe CHANCE trial. CNSNeurosci Ther. 2014; 20(12):1029-1035. (IF=4.8)

111.Pan Y#, Chen Q#,Zhao X, Liao X, Wang C, Du W, Liu G, Liu L, Wang C, Wang Y*, Wang Y*.Cost-effectivenessof thrombolysis within 4.5 hours of acute ischemic stroke in China. PLoS One. 2014;9(10):e110525. (IF=2.9)

112.Pan Y, JingJ, Zhang R, Zhao X, Liu L, Wang H, Liu G, Wang C, Wang Y*, Wang Y*.Poor performanceof stroke prognostication using Age and National Institutes of Health StrokeScale-100 to predict 3- and 12-month outcomes of ischemic stroke in ChinaNational Stroke Registry. J StrokeCerebrovasc Dis. 2014;23(9):2335-2340. (IF=2.0)

113. Pan Y#, Wang A#, Liu G, Zhao X, Meng X, Zhoa K, Liu L,Wang C, Johnston C, Wang Y*, Wang Y*. Cost–effectivenessof clopidogrel-aspirin versus aspirin alone for acute TIA and minor stroke. J Am Heart Assoc. 2014;3(3):e000912. (IF=5.0)

114.Pan YS#, Jing J#, Wang YL, Zhao XQ, Song B, Wang WJ, Wang D, Liu GF,Liu LP, Wang CX, Wang YJ*. Use of statin during hospitalization improvesthe outcome after intracerebral hemorrhage. CNS Neurosci Ther. 2014; 20(6):548–555. (IF=4.8)

代表性成果：

1. “脑血管病医疗质量改进关键技术与体系的建立和应用”2020年获国家科学技术进步奖二等奖(排名第8)(编号：2020-J-233-2-07-R08) 授予机构：国务院

2. “灌注CT指导下的缺血性脑卒中的动脉溶栓取栓治疗”2019年获浙江省科学技术进步奖三等奖 (排名第3)(编号：2019-J-3-078-R03) 授予机构：浙江省人民政府