附属北京儿童医院-倪鑫导师介绍

更新于 2022-08-16 导师主页
倪鑫 主任医师 硕,博士生导师
附属北京儿童医院
耳鼻咽喉科学 ,儿外科学
头颈肿瘤的基础与临床研究,儿外科学,头颈外科临床与基础研究
nixin@bch.com.cn

倪鑫:耳鼻咽喉头颈外科知名专家,教授,博士生导师,享受国务院政府特殊津贴专家。现任国家儿童医学中心主任,国家儿童肿瘤监测中心主任,首都医科大学附属北京儿童医院院长,北京市儿科研究所所长,首都医科大学儿科医学院院长。兼任国务院深化医药卫生体制改革领导小组专家咨询委员会委员;中华医学会儿外科分会主任委员,中国医师协会小儿外科医师分会会长,中国医院协会儿童医院分会主任委员;福棠儿童医学发展研究中心理事会主席。《PediatricInvestigation》主编、《中国耳鼻咽喉头颈外科》、《国外医学耳鼻咽喉科学分册》等杂志编委,国家级规划教材《耳鼻咽喉头颈外科》编委。

主持各类科研课题46项,其中国家级和省部级科研项目30项。发表学术论文200余篇,其中SCI论文110余篇。出版著作21部,其中主编(译)/副主编(译)著作18部。获国家科技成果奖、北京科学技术进步奖二等奖、北京医学科技奖一等奖、北京市教学成果一等奖、北京市科学技术奖三等奖、河北省科学技术奖三等奖、宋庆龄儿科医学奖、中华医学科技奖管理奖、中国医院协会医院科技创新奖等奖项。获批专利13项,其中发明专利5项。

先后获得“北京市卫生系统“十百千”卫生人才“十”层次人选”、“健康中国2014年度健康促进卓越院长”、第九届中国医师奖、2015“华仁杯”最具领导力中国医院院长、2015推进医改-服务百姓健康十大新闻人物、2015首都十大健康卫士提名奖、“2015-2016年度中国儿科杰出贡献人物”、2018年全国优秀医院院长、国家名医盛典国之名医优秀风范、2019北京市有突出贡献的科学、技术、管理人才、北京市医院管理中心“登峰”人才团队负责人、“敬佑生命,荣耀医者”金柳叶刀奖等荣誉。


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科研项目

1.      2015.01-2018.12国家自然科学基金 幼年型复发性呼吸道乳头状瘤(JO-RRP)T细胞免疫机制研究(31470862)

2.      2016.02-2016.12中国工程院研究项目2016医学前沿论坛-儿童上气道疾病医学前沿论坛(2016-XBXS-48)

3.      2016.01-2016.12国家卫生计生委员会 建立中国儿童临床常规检验指标参考区间     

4.      2017.07-2017.12国家发改委地区经济司 基于儿童多发疾病医教研用协同创新平台的京津冀共同体建设研究

5.      2018.01-2021.12北京市科学技术委员会北京市科技计划 基于人工智能的儿童社区获得性肺炎与罕见遗传病辅助诊断系统研发     

6.      2018.01-2020.12 首都卫生发展科研专项项目 阻塞性睡眠呼吸暂停综合征对儿童认知功能的影响研究及临床干预疗效评价的初探

7.      2018.01-2018.12国家卫生计生委员会 建立中国儿童临床常规检验指标参考区间     

8.      2018.01-2020.12科技部国家科技重大专项 儿童用药品种及关键技术研发

9.      2018.01-2019.12中国工程院 加强基层医生队伍建设—完善我国儿童肿瘤专业人才培养体系研究

10.   2019.01-2021.12北京航空航天大学高精尖创新分中心 基于儿童大数据的精准医疗研究

11.   2020.01-2023.12国家自然科学基金 NLRP3介导的细胞焦亡在儿童呼吸道上皮细胞乳头状增生中的作用机制

12.   2019.10-2020.09国家卫生健康委员会 《儿童临床生化常规检验项目参考区间》标准项目

13.   2019.10-2020.09国家卫生健康委员会 《儿童血细胞分析参考区间》标准项目

14.   2020.09-2021.09首都医科大学附属北京儿童医院院内研究平台专项 肿瘤患儿主索引体系构建及信息化实现方式研究

15.   2020.11-2023.10北京市自然科学基金 TNIK在甲状腺乳头状癌中的作用机制和临床应用研究


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研究成果

主编或副主编的著作/译著

1、《诸福棠实用儿科学(第8版)》 执行主编 人民卫生出版社 2015

2、《实用儿童耳鼻咽喉头颈科学(第2版)》 主编 人民卫生出版社 2021

3、《张金哲小儿外科学(第2版)》 副主编 人民卫生出版社 2021

4、《耳鼻咽喉头颈外科学(第3版)》 副主编 人民卫生出版社 2021

5、《罗顿颅脑颈部解剖彩色图谱(中文翻译版)》 主译 科学出版社 20190601

6、《儿童头颈肿瘤(翻译版)》 主译 人民卫生出版社 20190301

重要学术论文 

 1. LiuW, Chen M, Liu B, Zhang J, Ni X: Clinical Analysis of Type II FirstBranchial Cleft Anomalies in Children. LARYNGOSCOPE 2021, 131(4):916-920.DOI: 10.1002/lary.29049.

  2. SongF, Zeng Y, Tian J, Lv Y, Feng G, Ni X: Epidemiology and the economic burdenof pediatric fractures in China: A retrospective study of 14,141 fractures.BONE 2021, 144:115498. DOI: 10.1016/j.bone.2020.115498.

  3. HanZ, Tai J, Gao J, Wang S, Yu T, Peng Y, Ni X: MRI in Children With PyriformSinus Fistula. J MAGN RESON IMAGING 2021, 53(1):85-95. DOI:10.1002/jmri.27325.

  4. DuanQ, Zhang F, Wang G, Wang H, Li H, Zhao J, Zhang J, Ni X: Vocal cordparalysis following lithium button battery ingestion in children. EUR JPEDIATR 2021, 180(4):1059-1066. DOI: 10.1007/s00431-020-03830-1.

  5. LiY, Zhang W, Yang Y, Liu B, Chen M, Liu W, Li B, Zhou Y, Zhang J, Ni X: Developmentalperformance among pediatric candidates for cochlear implantation. ACTAOTO-LARYNGOL 2021, 141(1):66-72. DOI: 10.1080/00016489.2020.1821914.

  6. WangW, Xu Z, Zhang J, Wang S, Ge W, Li X, Mou W, Wang X, Chai W, Zhao J, Wang G, XiY, Qiu Y, Ji T, Gui J, Tai J, Ni X: Tim-3 is a potential regulator thatinhibits monocyte inflammation in response to intermittent hypoxia in childrenwith obstructive sleep apnea syndrome. CLIN IMMUNOL 2021, 222:108641.DOI: 10.1016/j.clim.2020.108641.

  7. GuanY, Yang H, Yao X, Xu H, Liu H, Tang X, Hao C, Zhang X, Zhao S, Ge W, Ni X: Clinicaland Genetic Spectrum of Children With Primary Ciliary Dyskinesia in China. CHEST2021, 159(5):1768-1781. DOI: 10.1016/j.chest.2021.02.006.

  8. XuZ, Ni X: Debates in pediatric obstructive sleep apnea treatment. WorldJournal of Otorhinolaryngology - Head and Neck Surgery 2021, 7(3):194-200.DOI: 10.1016/j.wjorl.2021.05.001.

  9. YuY, Wang S, Zhang X, Xu S, Li Y, Liu Q, Yang Y, Sun N, Liu Y, Zhang J, Guo Y, NiX: Clinical implications of TPO and AOX1 in pediatric papillary thyroidcarcinoma. Translational Pediatrics 2021, 10(4):723-732. DOI:10.21037/tp-20-301.

 10. BaiG, Hu K, Huan Y, Wang X, Lei L, Zhang M, Guo C, Chang H, Zhao L, Liu J, Shen Z,Wang X, Ni X: The Traditional Chinese Medicine Fuyou Formula AlleviatesPrecocious Puberty by Inhibiting GPR54/GnRH in the Hypothalamus. FRONTPHARMACOL 2021, 11:596525. DOI: 10.3389/fphar.2020.596525.

 11. MaY, Wang Y, Shi Y, Shi L, Wang L, Li Z, Li G, Zhang Y, Fan L, Ni X: Mediatingrole of coping styles on anxiety in healthcare workers victim of violence: a cross-sectionalsurvey in China hospitals. BMJ OPEN 2021, 11(7):e48493. DOI:10.1136/bmjopen-2020-048493.

 12. ZhangY, Liu X, Guo R, Xu W, Guo Q, Hao C, Ni X, Li W: Biological implications ofgenetic variations in autism spectrum disorders from genomics studies. BIOSCIENCEREP 2021, 41(7). DOI: 10.1042/BSR20210593.

 13. WangS, Mei L, Li Y, Zhang X, Zhang J, Ge W, Guo Y, Yu Y, Wang G, Mei T, Liu Q, SunN, He Y, Li X, Liu Y, Tai J, Ni X: Application of Gastroscopy in theDiagnosis of Congenital Pyriform Sinus Fistula in Children. FRONTPEDIATR 2021, 8:541249. DOI: 10.3389/fped.2020.541249.

 14. Wu Y, Zheng L, Wu P, Tang Y, XuZ, Ni X: Clinical and PSG Characteristics of Children with Mild OSA andRespiratory Events Terminated Predominantly with Arousal. CAN RESPIR J2021, 2021:1-7. DOI: 10.1155/2021/5549423.

 15. Ji T, Li X, Qiu Y, Mei L, JiaX, Tai J, Guo Y, Zhang J, Wang S, Ni X: Disease characteristics andneuropathological changes associated with cognitive dysfunction in obstructivesleep apnea. Pediatric Investigation 2021, 5(1):52-57. DOI:10.1002/ped4.12247.

 16. Fang X, Wang S, Zhao J, ZhangY, Zhang J, Li Y, Li X, Tai J, Ni X: A population-based analysis of clinicalfeatures and lymph node dissection in head and neck malignant neurogenic tumors.BMC CANCER 2021, 21(1):598. DOI: 10.1186/s12885-021-08307-4.

 17. Li Y, Wang S, Tai J, Zhang J,He L, Zhang N, Zhang X, Liu Q, Sun N, Ni X: Surgical Experiences ofPediatric Cervical Bronchogenic Cysts: A Case Series of 6 Patients. Ear,Nose & Throat Journal 2021:487932075. DOI: 10.1177/0145561320982194.

 18. Bai G, Wu T, Zhao L, Wang X, LiS, Ni X: CBDPS 1.0: A Python GUI Application for Machine Learning Models toPredict Bitter-Tasting Children's Oral Medicines. Chem Pharm Bull(Tokyo) 2021, 69(10):989-994. DOI: 10.1248/cpb.c20-00866.

 19. Sun N, Yang Y, Wang S, Zhang J,Gui J, Tai J, He L, Xu J, Li Y, Zhang X, Liu Q, Liu Z, Guo Y, Ni X: DCX andCRABP2 are candidate genes for differential diagnosis between pre-chemotherapyembryonic and alveolar rhabdomyosarcoma in pediatric patients. PediatrInvestig 2021, 5(2):106-111. DOI: 10.1002/ped4.12278.

 20. Wang S, Wang W, Zhang X, Gui J,Zhang J, Guo Y, Liu Y, Han L, Liu Q, Li Y, Sun N, Liu Z, Du J, Tai J, Ni X: Asomatic mutation in PIK3CD unravels a novel candidate gene for lymphaticmalformation. ORPHANET J RARE DIS 2021, 16(1):208. DOI: 10.1186/s13023-021-01782-9.

 21. Yang Y, Liu W, Jin Y, Chen M,Lu J, Yu Y, Ren H, Han S, Chu P, Guo Y, Zhang J, Ni X: Identification ofpotential pathogenic mutations in Chinese children with first branchial cleftanomalies detected by whole‐exome sequencing. PediatricInvestigation 2021, 5(3):211-216. DOI: 10.1002/ped4.12263.

 22. Xu Z, Ma D, Wu Y, Wang L, ZhangY, Ni X: Generation and characterization of iPSC lines (BCH001) from a boywith intron 14 mutation in the ret proto-oncogene (RET) gene. STEM CELLRES 2021, 53:102359. DOI: 10.1016/j.scr.2021.102359.

 23. Hao C, Guo R, Hu X, Qi Z, GuoQ, Liu X, Liu Y, Sun Y, Zhang X, Jin F, Wu X, Cai R, Zeng D, Hu X, Wang X, JiX, Li W, Xing Q, Mu L, Jiang X, Yang X, Yang W, Zhang Y, Yin Q, Ni X, Li W: Newbornscreening with targeted sequencing: a multicenter investigation and a pilotclinical study in China. J GENET GENOMICS 2021. DOI:10.1016/j.jgg.2021.08.008.

 24. DingW, Chen J, Feng G, Chen G, Wu J, Guo Y, Ni X, Shi T: DNMIVD: DNA methylationinteractive visualization database. NUCLEIC ACIDS RES 2020, 48(D1):D856-D862.DOI: 10.1093/nar/gkz830.

 25. LiuH, Liu Y, Li Y, Jin X, Li J, Zhou Y, Ge W, Ni X: Effect of AdaptiveCompression and Fast-Acting WDRC Strategies on Sentence Recognition in Noise inMandarin-Speaking Pediatric Hearing Aid Users. J AM ACAD AUDIOL2020, 29(04):273-278. DOI: 10.3766/jaaa.16086.

 26. SongB, Zheng H, Han S, Tang L, Yang X, Chu P, Wang P, Lu J, Ge W, Ni X: Detectionof nasal microbiota in pediatric patients with antrochoanal polyps by TLDA.INT J PEDIATR OTORHI 2020, 130:109811. DOI:10.1016/j.ijporl.2019.109811.

 27. YangY, Chen M, Zheng J, Hao J, Liu B, Liu W, Li B, Shao J, Liu H, Ni X, Zhang J: Clinicalevaluation of cochlear implantation in children younger than 12 months of age.PEDIATRIC INVESTIGATION 2020, 4(2):99-103. DOI:10.1002/ped4.12202.

 28. FangX, Wang H, Ma X, Guo Y, Yang W, Hu S, Qiu Y, Zhao J, Ni X: Clinical Featuresof Children with Retinoblastoma and Neuroblastoma. J OPHTHALMOL2020, 2020:1-8. DOI: 10.1155/2020/9315784.

 29. LiK, Hu L, Peng Y, Yan R, Li Q, Peng X, Song W, Ni X: Comparison of fouralgorithms on establishing continuous reference intervals for pediatricanalytes with age-dependent trend. BMC MED RES METHODOL 2020, 20(1):136.DOI: 10.1186/s12874-020-01021-y.

 30. ShiJ, Ren M, Jia J, Tang M, Guo Y, Ni X, Shi T: Corrigendum: Genotype–Phenotype Association Analysis Reveals New PathogenicFactors for Osteogenesis Imperfecta Disease. FRONT PHARMACOL 2020, 10:1603. DOI: 10.3389/fphar.2019.01603.

 31. SunN, Ye J, Zhang J, Kang D, Tai J, Wang S, Zhang J, Ni X: Efficacy ofVelopharyngeal Surgery for Positional Obstructive Sleep Apnea Hypopnea Syndrome.Ear, Nose & Throat Journal 2020:487927051. DOI:10.1177/0145561320931956.

 32. LiuQ, Wang S, Zhang J, Zhang X, Li Y, Zhao J, Ge W, Liu Y, Wang G, Sun N, Tai J,Siu AK, Ni X: Endoscopy-assisted, transoral submucosal coblation forpediatric retropharyngeal lymphatic malformations. INT J PEDIATR OTORHI2020, 134:110074. DOI: 10.1016/j.ijporl.2020.110074.

 33. WangG, He L, Wang S, Zhang M, Li Y, Liu Q, Sun N, Zhang X, Liu Y, Zhang J, Tai J,Ni X: EV PD-L1 is Correlated With Clinical Features and Contributes to TCell Suppression in Pediatric Thyroid Cancer. The Journal of ClinicalEndocrinology & Metabolism 2020, 105(8):e2970-e2981. DOI:10.1210/clinem/dgaa309.

 34. RenM, Shi J, Jia J, Guo Y, Ni X, Shi T: Genotype-phenotype correlations ofBerardinelli-Seip congenital lipodystrophy and novel candidate genes prediction.ORPHANET J RARE DIS 2020, 15(1):108. DOI:10.1186/s13023-020-01383-y.

 35. ZhangW, Tang L, Wang P, Ge W, Ni X: Intranasal glial heterotopia in a male infant.MEDICINE 2020, 99(29):e21200. DOI: 10.1097/MD.0000000000021200.

 36. Fang X, Chen J, Wang W, Feng G,Li X, Zhang X, Zhang Y, Zhang J, Xu Z, Tai J, Ni X: Matrix metalloproteinase9 (MMP9) level and MMP9 -1562C>T in patients with obstructive sleep apnea: asystematic review and meta-analysis of case-control studies. SLEEP MED2020, 67:110-119. DOI: 10.1016/j.sleep.2019.11.1247.

 37. Wang G, Zhang F, Zhao J, WangH, Li H, Wang X, Zhang J, Ni X: Minimally invasive procedure for diagnosisand treatment of vallecular cysts in children: review of 156 cases. EURARCH OTO-RHINO-L 2020, 277(12):3407-3414. DOI: 10.1007/s00405-020-06163-9.

 38. He Y, Song H, Liu P, Sun N,Tian J, Li M, Li N, Qu Y, Han W, Feng G, Ni X, Zhang W: Primary laparoscopicpyeloplasty in children: A single-center experience of 279 patients andanalysis of possible factors affecting complications. J PEDIATR UROL2020, 16(3):331. DOI: 10.1016/j.jpurol.2020.03.028.

 39. Xi Y, Wang H, Wang W, Wang X,Zhang J, Zhao J, Wang G, Gui J, Ni X: Risk factors for aggressive recurrentrespiratory papillomatosis in Chinese juvenile patients. ACTA OTO-LARYNGOL2020, 140(9):771-776. DOI: 10.1080/00016489.2020.1767804.

 40. Xu Z, Wu Y, Tai J, Feng G, GeW, Zheng L, Zhou Z, Ni X: Risk factors of obstructive sleep apnea syndromein children. Journal of Otolaryngology - Head & Neck Surgery2020, 49(1):11. DOI: 10.1186/s40463-020-0404-1.

 41. Guan Y, Yang H, Yao X, Xu H,Liu H, Tang X, Hao C, Zhang X, Zhao S, Ge W, Ni X: WITHDRAWN: Clinical andGenetic Spectrum of Children with Primary Ciliary Dyskinesia in China. CHEST2020. DOI: 10.1016/j.chest.2020.06.045.

 42. Hao J, Chen M, Liu B, Yang Y,Liu W, Zhang J, Ni X: The Significance of Staging in the Treatment ofCongenital Cholesteatoma in Children. Ear, Nose & Throat Journal2020:487927252. DOI: 10.1177/0145561320933965.

 43. Li K, Peng Y, Yan R, Song W,Peng X, Ni X: Age-dependent changes of total and differential white bloodcell counts in children. CHINESE MED J-PEKING 2020, 133(16):1900-1907.DOI: 10.1097/CM9.0000000000000854.

 44. Liu J, Wu Y, Wu P, Xu Z, Ni X: Analysisof the impact of allergic rhinitis on the children with sleep disorderedbreathing. INT J PEDIATR OTORHI 2020, 138:110380. DOI:10.1016/j.ijporl.2020.110380.

 45. Su Y, Qin H, Chen C, Wang S,Zhang S, Zhang D, Jin M, Peng Y, He L, Wang X, Qian S, Qin M, Ge M, Zhang F,Zeng Q, Wang H, Ma X, Ni X: Treatment and outcomes of 1041 pediatricpatients with neuroblastoma who received multidisciplinary care in China. PediatricInvestigation 2020, 4(3):157-167. DOI: 10.1002/ped4.12214.

 46. Li Y, Wang S, Tai J, Zeng Q,Zhang J, Liu Y, Ge W, Huang Y, Zhang X, Liu Q, Sun N, Chen C, Ni X: SurgicalTreatment of Cervicothoracic Junction Lesions in Children: A Series of 18 Cases.J INVEST SURG 2020:1-5. DOI: 10.1080/08941939.2020.1839821.

 47. XuZ, Gutiérrez-Tobal GC, Wu Y, Kheirandish-Gozal L, Ni X, Hornero R, Gozal D: Cloudalgorithm-driven oximetry-based diagnosis of obstructive sleep apnoea insymptomatic habitually snoring children. EUR RESPIR J 2019, 53(2):1801788.DOI: 10.1183/13993003.01788-2018.

 48. YuY, Yang Y, Lu J, Jin Y, Yang Y, Hong E, Shi J, Chen F, Han S, Chu P, Guo Y, NiX: Two Compound Heterozygous Were Identified in SLC26A4 Gene in TwoChinese Families With Enlarged Vestibular Aqueduct. CLIN EXP OTORHINOLAR2019, 12(1):50-57. DOI: 10.21053/ceo.2018.00213.

 49. ZhaoY, Li Y, Zheng Z, Li J, Nie X, Jin X, Zheng J, Zhang J, Chen M, Hao J, Yang Y,Liu W, Liu H, Ni X: Health-Related Quality of Life in Mandarin-SpeakingChildren With Cochlear Implants. Ear & Hearing 2019, 40(3):605-614.DOI: 10.1097/AUD.0000000000000633.

 50. ShiJ, Ren M, Jia J, Tang M, Guo Y, Ni X, Shi T: Genotype–Phenotype Association Analysis Reveals New PathogenicFactors for Osteogenesis Imperfecta Disease. FRONT PHARMACOL 2019, 10:1200. DOI:10.3389/fphar.2019.01200.

 51. FuY, Jia J, Yue L, Yang R, Guo Y, Ni X, Shi T: Systematically Analyzing thePathogenic Variations for Acute Intermittent Porphyria. FRONT PHARMACOL2019, 10:1018. DOI: 10.3389/fphar.2019.01018.

 52. ZhaoY, Li Y, Long Y, Jin X, Zheng Z, Liu Y, Wang Y, Zheng J, Zhang J, Chen M, HaoJ, Yang Y, Liu W, Liu H, Ni X: Comparison of the development of earlyauditory and preverbal skills in Mandarin-Speaking children with cochlearimplants with and without additional disabilities. ACTA OTO-LARYNGOL2019, 139(12):1098-1103. DOI: 10.1080/00016489.2019.1670358.

 53. WuY, Feng G, Xu Z, Li X, Zheng L, Ge W, Ni X: Identification of differentclinical faces of obstructive sleep apnea in children. INT J PEDIATROTORHI 2019, 127:109621. DOI: 10.1016/j.ijporl.2019.109621.

 54. GengJ, Liu Y, Guo Y, Wang H, Tai J, Jin Y, Zhang J, Yu Y, Wang S, Song Y, Ni X: Correlationbetween TERT C228T and clinic-pathological features in pediatric papillarythyroid carcinoma. Science China Life Sciences 2019, 62(12):1563-1571.DOI: 10.1007/s11427-018-9546-5.

 55. ShiJ, Yu Y, Jin Y, Lu J, Zhang J, Wang H, Han W, Chu P, Tai J, Chen F, Ren H, GuoY, Ni X: Functional Polymorphisms inBARD1 Association with Neuroblastoma ina regional Han Chinese Population. J CANCER 2019, 10(10):2153-2160.DOI: 10.7150/jca.26719.

 56. Zheng H, Tang L, Song B, YangX, Chu P, Han S, Wang P, Lu J, Ge W, Ni X: Inflammatory patterns ofantrochoanal polyps in the pediatric age group. Allergy, Asthma &Clinical Immunology 2019, 15(1):39. DOI: 10.1186/s13223-019-0352-3.

 57. Hao J, Chen M, Liu B, Yang Y,Liu W, Ma N, Han Y, Liu Q, Ni X, Zhang J: Correction to: Compare twosurgical interventions for otitis media with effusion in young children. EURARCH OTO-RHINO-L 2019, 276(8):2133-2134. DOI:10.1007/s00405-019-05510-9.

 58. Yu Y, Chen F, Yang Y, Jin Y,Shi J, Han S, Chu P, Lu J, Tai J, Wang S, Yang W, Wang H, Guo Y, Ni X: lncRNASNHG16 is associated with proliferation and poor prognosis of pediatricneuroblastoma. INT J ONCOL 2019, 55(1):93-102. DOI:10.3892/ijo.2019.4813.

 59. Wang S, Du J, Liu Y, Zhang J,Ge W, Zhang Y, Guo Y, Li Y, Zhang X, Li X, Yu Y, Jin Y, He Y, Shi J, Tai J, NiX: Clinical analysis of surgical treatment for head and neck lymphaticmalformations in children: a series of 128 cases. ACTA OTO-LARYNGOL2019, 139(8):713-719. DOI: 10.1080/00016489.2019.1616818.

 60. Hao J, Chen M, Liu B, Yang Y,Liu W, Ma N, Han Y, Liu Q, Ni X, Zhang J: Compare two surgical interventionsfor otitis media with effusion in young children. EUR ARCH OTO-RHINO-L2019, 276(8):2125-2131. DOI: 10.1007/s00405-019-05421-9.

 61. Zheng H, Liu D, Lu J, Song Y,Wang S, Zhao Y, Ni X: Genetic Correlation of Antibiotic Susceptibility andResistance Genotyping for theMycobacterium abscessus              Group. ANTIMICROB AGENTSCH 2019, 63(1). DOI: 10.1128/AAC.01523-18.

 62. Yang C, Chen T, Ni X, Yu W,Wang W: Effect of pre-administration with aminophylline on the occurrence ofpost-dural puncture headache in women undergoing caesarean section by combinedspinal-epidural anaesthesia. J INT MED RES 2019, 47(1):420-426.DOI: 10.1177/0300060518803231.

 63. MeiD, Zhao L, Chen B, Zhang X, Wang X, Yu Z, Ni X, Zhang Q: α-Conotoxin ImI-modified polymeric micelles as potentialnanocarriers for targeted docetaxel delivery to α7-nAChR overexpressed non-small cell lung cancer. DRUG DELIV 2018, 25(1):493-503. DOI:10.1080/10717544.2018.1436097.

 64. ZhangF, Wu Y, Feng G, Ni X, Xu Z, Gozal D: Polysomnographic correlates ofendothelial function in children with obstructive sleep apnea. SLEEP MED2018, 52:45-50. DOI: 10.1016/j.sleep.2018.07.023.

 65. ZhangL, Lv C, Jin Y, Cheng G, Fu Y, Yuan D, Tao Y, Guo Y, Ni X, Shi T: DeepLearning-Based Multi-Omics Data Integration Reveals Two Prognostic Subtypes inHigh-Risk Neuroblastoma. FRONT GENET 2018, 9:477. DOI:10.3389/fgene.2018.00477.

 66. JiaJ, An Z, Ming Y, Guo Y, Li W, Liang Y, Guo D, Li X, Tai J, Chen G, Jin Y, LiuZ, Ni X, Shi T: eRAM: encyclopedia of rare disease annotations for precisionmedicine. NUCLEIC ACIDS RES 2018, 46(D1):D937-D943. DOI:10.1093/nar/gkx1062.

 67. JiaJ, An Z, Ming Y, Guo Y, Li W, Li X, Liang Y, Guo D, Tai J, Chen G, Jin Y, LiuZ, Ni X, Shi T: PedAM: a database for Pediatric Disease Annotation andMedicine. NUCLEIC ACIDS RES 2018, 46(D1):D977-D983. DOI:10.1093/nar/gkx1049.

 68. WangS, He Y, Zhang Y, Zhang J, Shah R, Feng G, Li X, Ge W, Liu Y, Guo Y, Liu H, TaiJ, Ni X: CO 2 laser cauterization approach to congenital pyriform sinusfistula. J PEDIATR SURG 2018, 53(7):1313-1317. DOI:10.1016/j.jpedsurg.2017.06.020.

 69. TaiJ, Wang S, Zhang J, Ge W, Liu Y, Li X, Liu Y, Deng Z, He L, Wang G, Ni X: Up-regulatedlipocalin-2 in pediatric thyroid cancer correlated with poor clinicalcharacteristics. EUR ARCH OTO-RHINO-L 2018, 275(11):2823-2828.DOI: 10.1007/s00405-018-5118-x.

 70. LiX, Tai J, Xu Z, Ma J, Peng X, Pan Y, Yan X, Wang G, Wu Y, Zheng L, Du J, Ge W,Zhang J, Zhang Y, Ni X: Systematic investigation of childhoodsleep-disordered breathing (SDB) in Beijing: validation of survey methodology.BMJ OPEN 2018, 8(8):e21097. DOI: 10.1136/bmjopen-2017-021097.

 71. YuY, Zhang J, Jin Y, Yang Y, Shi J, Chen F, Han S, Chu P, Lu J, Wang H, Guo Y, NiX: MiR-20a-5p suppresses tumor proliferation by targeting autophagy-relatedgene 7 in neuroblastoma. CANCER CELL INT 2018, 18(1):5. DOI: 10.1186/s12935-017-0499-2.

 72. Jin Y, Zhang L, Ning B, Hong H,Xiao W, Tong W, Tao Y, Ni X, Shi T, Guo Y: Application of genome analysisstrategies in the clinical testing for pediatric diseases. PediatricInvestigation 2018, 2(2):72-81. DOI: 10.1002/ped4.12044.

 73. Li X, Tai J, Xu Z, Wang G, WuY, Du J, Zhang J, Peng X, Ni X: Sleep Duration and Factors Related to SleepLoss in 3–14-Year-Old Children in Beijing. CHINESE MED J-PEKING 2018, 131(15):1799-1807. DOI:10.4103/0366-6999.237403.

 74. Liu W, Zhao S, Shi L, Zhang Z,Liu X, Li L, Duan X, Li G, Lou F, Jia X, Fan L, Sun T, Ni X: Workplaceviolence, job satisfaction, burnout, perceived organisational support and theireffects on turnover intention among Chinese nurses in tertiary hospitals: across-sectional study. BMJ OPEN 2018, 8(6):e19525. DOI:10.1136/bmjopen-2017-019525.

 75. Peng X, Lv Y, Feng G, Peng Y,Li Q, Song W, Ni X: Algorithm on age partitioning for estimation ofreference intervals using clinical laboratory database exemplified with plasmacreatinine. Clinical Chemistry and Laboratory Medicine (CCLM) 2018, 56(9):1514-1523.DOI: 10.1515/cclm-2017-1095.

 76. Gao Q, Huang H, Zhu K, Liu X,Hou X, Guan H, Liu Y, Xin D, Xiang L, Shen K, Ni X: Clinical Course andFactors Associated with Asthma Control in Children under Control-based AsthmaManagement: A Prospective Study. Iran J Allergy Asthma Immunol 2018,17(1):18-28.

 77. Chen F, Jin Y, Feng L, Zhang J,Tai J, Shi J, Yu Y, Lu J, Wang S, Li X, Chu P, Han S, Cheng S, Guo Y, Ni X: RRS1gene expression involved in the progression of papillary thyroid carcinoma.CANCER CELL INT 2018, 18(1):20. DOI: 10.1186/s12935-018-0519-x.

 78. Li X, Ni X, Qian S, Wang Q,Jiang R, Xu W, Zhang Y, Yu G, Chen Q, Shang Y, Zhao C, Yu H, Zhang T, Liu G,Deng H, Gao J, Ran X, Yang Q, Xu B, Huang X, Wu X, Bao Y, Chen Y, Chen Z, LiuQ, Lu G, Liu C, Wang R, Zhang G, Gu F, Xu H, Li Y, Yang T: Chineseguidelines for the diagnosis and treatment of hand, foot and mouth disease(2018 edition). WORLD J PEDIATR 2018, 14(5):437-447. DOI:10.1007/s12519-018-0189-8.

 79. Zhao J, Han S, Zhang J, Wang G,Wang H, Xu Z, Tai J, Peng X, Guo Y, Liu H, Tian J, Jin X, Zheng L, Zhang J, NiX: Association between mild or moderate obstructive sleep apnea-hypopneasyndrome and cognitive dysfunction in children. SLEEP MED 2018, 50:132-136.DOI: 10.1016/j.sleep.2018.04.009.

 80. Zhang L, Jin Y, Zheng K, WangH, Yang S, Lv C, Han W, Yu Y, Yang Y, Geng D, Yang H, Shi T, Guo Y, Ni X: Whole-GenomeSequencing Identifies a Novel Variation of WAS Gene Coordinating WithHeterozygous Germline Mutation of APC to Enhance Hepatoblastoma Oncogenesis.FRONT GENET 2018, 9:668. DOI: 10.3389/fgene.2018.00668.

 81. YangX, Guo Y, Ni X, Zhang J: An Unusual Case of a Large Subglottic Granuloma dueto Foreign Body Aspiration in an 11-Year-Old Boy. HONG KONG J EMERG ME2017, 24(1):37-39. DOI: 10.1177/102490791702400106.

 82. NiX, Shi T: The challenge and promise of rare disease diagnosis in China. ScienceChina Life Sciences 2017, 60(7):681-685. DOI:10.1007/s11427-017-9100-1.

 83. GengJ, Wang H, Liu Y, Tai J, Jin Y, Zhang J, He L, Fu L, Qin H, Song Y, Su J, ZhangA, Wen X, Guo Y, Ni X: Correlation between BRAF (V600E) mutation andclinicopathological features in pediatric papillary thyroid carcinoma. SCICHINA LIFE SCI 2017, 60(7):729-738. DOI: 10.1007/s11427-017-9083-8.

 84. FuL, Jin Y, Jia C, Zhang J, Tai J, Li H, Chen F, Shi J, Guo Y, Ni X, He L: Detectionof FOXO1 break-apart status by fluorescence in situ hybridization in atypicalalveolar rhabdomyosarcoma. Science China Life Sciences 2017, 60(7):721-728.DOI: 10.1007/s11427-017-9082-9.

 85. WangS, Zhang J, Ge W, Liu Y, Guo Y, Liu Y, Wang N, He Y, Tai J, Ni X: Efficacyand safety of oral sildenafil in treatment of pediatric head and neck lymphaticmalformations. ACTA OTO-LARYNGOL 2017, 137(6):674-678. DOI:10.1080/00016489.2016.1272135.

 86. XiaoY, Wu X, Ma L, Gui J, Bai L, Ni X, Wang J: Enhanced T H 2-like peripheraladaptive immune responses in Juvenile-onset Recurrent RespiratoryPapillomatosis (JORRP). IMMUNOL LETT 2017, 191:31-34. DOI:10.1016/j.imlet.2017.08.026.

 87. ZhaoJ, Wang G, Wang G, Wang H, Wang S, Tai J, Tang L, Gui J, Zhang J, Ni X: HLA-DRB1and HLA-DQB1 alleles in Chinese Han patients with Juvenile-Onset recurrentrespiratory papillomatosis. INT J PEDIATR OTORHI 2017, 102:119-122.DOI: 10.1016/j.ijporl.2017.04.017.

 88. RenX, Mou W, Su C, Chen X, Zhang H, Cao B, Li X, Wu D, Ni X, Gui J, Gong C: Increasein Peripheral Blood Intermediate Monocytes is Associated with the Developmentof Recent-Onset Type 1 Diabetes Mellitus in Children. INT J BIOL SCI2017, 13(2):209-218. DOI: 10.7150/ijbs.15659.

 89. YuY, Fu L, Wang S, Jin Y, Han S, Chu P, Lu J, Guo Y, He L, Ni X: Investigationof IGF2, IGFBP2 and p63 proteins in rhabdomyosarcoma tumors. GROWTH HORMIGF RES 2017, 33:17-22. DOI: 10.1016/j.ghir.2017.01.002.

 90. WangP, Wang G, Ge W, Tang L, Zhang J, Ni X: Nasal nitric oxide in allergicrhinitis in children and its relationship to severity and treatment. Allergy,Asthma & Clinical Immunology 2017, 13(1):20. DOI:10.1186/s13223-017-0191-z.

 91. LvY, Feng G, Ni X, Song W, Peng X: The critical gap for pediatric referenceintervals of complete blood count in China. CLIN CHIM ACTA 2017, 469:22-25.DOI: 10.1016/j.cca.2017.03.017.

 92. LiuW, Chen X, Ni X: The modified temporalis muscle flap in reconstruction ofpalate and temporal deformity. ACTA OTO-LARYNGOL 2017, 137(8):899-902.DOI: 10.1080/00016489.2017.1300833.

 93. YangY, Haihong L, Jun Z, Min C, Ying L, Jinsheng H, Wei L, Jie Z, Xin N: Thevalue of Gesell score in predicting the outcome of cochlear implantation inchildren. EUR ARCH OTO-RHINO-L 2017, 274(7):2757-2763. DOI:10.1007/s00405-017-4601-0.

 94. JinY, Zhang L, Wang S, Chen F, Gu Y, Hong E, Yu Y, Ni X, Guo Y, Shi T, Xu Z: WholeGenome Sequencing Identifies Novel Compound Heterozygous Lysosomal TraffickingRegulator Gene Mutations Associated with Autosomal Recessive Chediak-HigashiSyndrome. SCI REP-UK 2017, 7(1):41308. DOI:10.1038/srep41308.


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学校介绍


  首都医科大学建校于1960年,是北京市重点高等院校,著名泌尿外科专家、中国科学院院士、中国工程院院士、原全国人大常委会副委员长吴阶平教授为首任院长。学校由校本部和附属医院(即临床医学院)组成。校本部设有基础医学院、生物医学工程学院、公共卫生与家庭医学学院、高等职业教育学院、中医药学院、顺义校区、继续教育学院、护理学院、卫生事业管理与发展学院及首都医科大学国际教学部;附属医院包括宣武医院(第一临床医学院)、附属北京友谊医院(第二临床医学院)、附属北京朝阳医院(第三临床医学院)、附属北京同仁医院(第四临床医学院)、附属北京天坛医院(第五临床医学院)、附属北京安贞医院(第六临床医学院)、附属北京口腔医院(口腔医学院)、附属北京儿童医院(儿科医学院)、附属北京妇产医院(妇产医学院)、附属北京安定医院(精神卫生学院)、附属复兴医院(第八临床医学院)、附属北京中医医院(中医药临床医学院)和康复医学院。

  学校和附属医院现有教职员工和医护人员22575人。有院士4人,正高职称700余人,副高职称1800余人。学校学科专业齐全,学科力量雄厚,在基础和临床各专业拥有一大批具有很高造诣的专家学者,现有3个国家级重点学科,有38个博士学位授予权学科,58个硕士学位授予权学科和2个博士后科研流动站。

  校本部和附属医院总占地面积97.3万平方米,总建筑面积134万平方米 ,固定资产总值近46.5亿元,图书馆藏书108.3万册 ,住院病床10039张。学校开办的七年制专业中设有临床医学和口腔医学;五年制专业中设有临床医学、口腔医学、预防医学、护理学、中医学等;四年制专业中设有生物医学工程、中药学和康复治疗学。在临床医学专业中设有儿科医学、康复医学、医学影像、精神卫生与精神病学和医学检验5个专业方向;在生物医学工程专业中设有医学影像设备与技术和听力学专业方向。高等职业教育设有护理、医学检验、药学、医学影像技术、康复技术、口腔修复工艺、眼科验光、实验动物技术、中医学、中药制剂、医学信息、临床医学、预防医学、中药经营贸易和中医学美容专业方向15个专业。首都医科大学现已成为以培养高层次本科生与研究生为核心、以临床应用型人才为主和培养预防、康复、生物医学工程和医学基础各学科、各层次人才,位于全国先进医学院校行列的高等学府。

  学校具有较强的学术发展与科研实力,在校本部和附属医院建有一批国家级和市级重点学科和重点实验室,建有高水平的国家级或市级研究和培训机构,如卫生部全科医学培训中心、临床医学研究所、基础医学研究所、神经科学研究所、眼科研究所、老年病医疗研究中心、泌尿外科研究所、心肺血管医疗研究中心、生命科学院、卫生毒理检测中心、生物工程技术研究中心、祖国医学研究所、临床疾病研究中心、中医肝病临床研究中心、生殖医学研究所、心血管疾病临床试验及社区干预中心和北京市卫生政策与卫生经济研究中心等。神经生物学、细胞生物学、电生理学、基础免疫学、实验寄生虫学、医学图像处理、生物医学、信息检测与处理、神经内科、神经外科、心脏内外科、肾移植、呼吸和消化内科、口腔颌面外科、眼科、耳鼻咽喉科、小儿血液病等领域在国内外享有较高声誉,很多学科的研究和医疗水平已经达到或接近国际先进水平。

  学校十分重视对外交流与合作,改革开放以来,先后与世界20多个国家和地区签定了友好交流协议, 近十年中,先后接待美国、加拿大、英国、澳大利亚、法国、瑞典、日本、荷兰、意大利、德国、丹麦及台湾、香港和澳门等50多个国家和地区的专家学者8000余人次来校进行学术交流和参观访问。同时,学校积极选送教师、科研人员和管理干部出国进修、参加学术会议和考察访问。

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