附属北京安贞医院-马骏导师介绍
马骏
主任医师
硕，博士生导师
女
附属北京安贞医院
麻醉学
心血管手术麻醉和危重症监测、神经病理性疼痛的诊治及研究
majun7689@163.com
教育经历
2004/03-2007/11，瑞典卡罗林斯卡医学院(Karolinska Institute) 分子医学与外科学系，医学博士
1997/02-1999/07，山东大学，麻醉学硕士
1985/09-1990/07，潍坊医学院，临床医学学士
工作经历
2013/01-至今，首都医科大学附属北京安贞医院，麻醉中心，教授、主任医师，博士研究生导师。
2009/04-2012/12，首都医科大学宣武医院，疼痛科，教授、主任医师，博士研究生导师。
1990/07-2009/03，潍坊医学院麻醉学系副主任、临床麻醉学教研室主任、麻醉学研究室主任、附属医院麻醉科副主任，硕士研究生导师。
展开更多
科研项目
研究成果
一、首都医科大学自然科学奖三等奖，《急性心肌梗死中心肌缺血再灌注损伤的线粒体机制研究》，2021.7，马骏，林多茂，杨艳丽，王兆麒，吴金晶，崔博群，张亮
二、《伴发心血管疾病患者围麻醉期处理》，副主编马骏，人卫出版社，2021
三、近5年首位作者或责任作者发表论文
1. Dongni Zhang , Chuan Ouyang, Xu Zhao, Boqun Cui, Feng Dai, Lingzhong Meng*, Jun Ma*. Renal tissue desaturation and acute kidney injury in infant cardiac surgery: A prospective propensity score-matched cohort study. British Journal of Anaesthesia, 2021，127 (4): 620-628. IF 11.719/Q1
2. Jinjing Wu, Yang Bai, Yaguang Wang, Jun Ma*. Melatonin and regulation of autophagy: mechanisms and therapeutic implications. Pharmacological Research, 2021,163:105279. https://doi.org/10.1016/j.phrs.2020.105279. IF 7.658/Q1
3. Yang Bai, Yanli Yang, Yafen Gao, Duomao Lin, Zhaoqi Wang, Jun Ma*. Melatonin postconditioning ameliorates anoxia/reoxygenation injury by regulating mitophagy and mitochondrial dynamics in a SIRT3-dependent manner. European Journal of Pharmacology, 2021, (904) 174157:1-12. IF 4.432/Q2
4. Li Y, Ma J, Jin Y, Li N, Zheng R, Mu W, Wang J, Si J, Chen J, Shang H. Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit. Cochrane Database of Systematic Reviews 2020, Issue 2. Art. No.: CD012670. DOI: 10.1002/14651858.CD012670.pub2
5. Zhaoqi Wang, Yan Li, Duomao Lin, Jun Ma.* Effect of Melatonin on Postoperative Pain and Perioperative Opioid Use: A Meta-analysis and Trial Sequential Analysis. Pain Practice, 2021,21( 2):190–203.
6. Yan Li, Zhi Dou, Liqiang Yang, Qi Wang, Jiaxiang Ni, Jun Ma*. Oxycodone versus other opioid analgesics after laparoscopic surgery: a meta-analysis. European journal of medical research. 2021 Jan 09;26(1):4 doi:10.1186/s40001-020-00463-w.
7. Cui B, Ou-Yang C, Xie S, Lin D, Ma J*. Effects of different ventilation on cerebral oxygen saturation and cerebral blood flow before and after modified ultrafiltration in infants during ventricular septal defect repair. Cardiol Young. 2021 Mar;31(3):371-376. doi: 10.1017/S1047951120003984. Epub 2021 Feb 5. PMID: 33541455.
8. YANLI YANG and JUN MA*. Mild AKI is associated with mortality of patients who underwent cardiopulmonary bypass surgery. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2020, 20: 2969-2974.
9. Sun H, He M, Pang J, Guo X, Huo Y, Ma J*. Continuous Lumbar Sympathetic Blockade Enhances the Effect of Lumbar Sympatholysis on Refractory Diabetic Neuropathy: A Randomized Controlled Trial. Diabetes Ther. 2020 Nov;11(11):2647-2655. doi: 10.1007/s13300-020-00918-7. Epub 2020 Sep 11. PMID: 32915421; PMCID: PMC7547930.
10. Cunlei Zhang, Jun Ma*. Chest X-ray Image Analysis and Penehyclidine Hydrochloride Postconditioning Influence of Lung Ischemia Reperfusion Injury. J. Med. Imaging Health Inf, 2020, 10:2834–2841
11. Cui B, Ou-Yang C, Xie S, Lin D, Ma J*. Age-related cerebrovascular carbon dioxide reactivity in children with ventricular septal defect younger than 3 years. Pediatr Anesth. 2020;00:1–7. https://doi.org/10.1111/ pan.13967
12. Congna Zi, Chunlei Zhang, Yanli Yang, Jun Ma*. Penehyclidine hydrochloride protects against anoxia/reoxygenation injury in cardiomyocytes through ATP‐sensitive potassium channels, and the Akt/GSK‐3β and Akt/mTOR signaling pathways. Cell Biol Int 44 (2020) 1353–1362
13. Wenyu Yao, Mingyuan Yang, Qinghao Cheng, Shiqiang Shan, Bo Yang, Qian Han, Jun Ma*. Effect of Pressure-Controlled Ventilation-Volume Guaranteed on One-Lung Ventilation in Elderly Patients Undergoing Thoracotomy. Med Sci Monit, 2020; 26: e921417-1- e921417-7. DOI: 10.12659/MSM.921417
14. Jinjing Wu, Yanli Yang, Yafen Gao, Zhaoqi Wang, Jun Ma*. Melatonin Attenuates Anoxia/Reoxygenation Injury by Inhibiting Excessive Mitophagy Through the MT2/SIRT3/FoxO3a Signaling Pathway in H9c2 Cells. Drug Design, Development and Therapy, 2020:14 2047–2060.
15. Li-yuan Wang, Jing Wu, Ya-fen Gao, Duo-mao Lin, Jun Ma*. Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells. Korean J Physiol Pharmacol 2020;24(1):19-26.
16. Lin D, Cui B, Ma J*, Ren J. MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1. BioFactors. 2019;1–11. https://doi.org/10.1002/biof.1571
17. JY Ren, DM Lin, CB Wang, YL Yang, ZQ Wang, BQ Cui, J Ma*. Postconditioning Protection Against Myocardiocyte Anoxia/Reoxygenation Injury From Penehyclidine Hydrochloride. Drug Design, Development and Therapy, 2019, 13: 3977–3988.
18. Li T, Qu W, Zhang X, Zhang Y, Ma J*. Puerarin alleviates cognitive dysfunction in rats after anesthesia with propofol. Int J Clin Exp Med 2019, 12(3):2697-2703.
19. Qinghao Cheng, Lei Li, Duomao Lin, Renjiao Li, Yun Yue, Huafeng Wei, Jun Ma. Effects of acute hypercapnia on cognitive function in patients undergoing bronchoscope intervention. Journal of Thoracic Disease, 2019, 11(3):1065-1071.
20. Qinghao Cheng, Lei Li, Mingyuan Yang, Lei Sun, Renjiao Li, Rui Huang, Jun Ma. Moderate hypercapnia may not contribute to postoperative delirium in patients undergoing bronchoscopic intervention. Medicine, 2019, 98:22:1-4.
21. Liang Zhang, Cheng-Bin Wang, Bo Li, Duo-Mao Lin, Jun Ma*. RhoA/rho-kinase, nitric oxide and inflammatory response in LIMA during OPCABG with isoflurane preconditioning. Journal of Cardiothoracic Surgery, 2019 Jan 25;14(1):22.
22. Mingwei He, Haiyan Sun, Jinlei Pang, Xiangfei Guo, Yansong Huo, Xianhong Wu, Yaguang Liu, Jun Ma. Propofol alleviates hypoxia-induced nerve injury in PC-12 cells by up-regulation of microRNA-153. BMC Anesthesiology, 2018, 18:197:1-10.
24. Yaguang Wang, Duomao Lin, Hongbao Tan, Yafen Gao, Jun Ma, Penehyclidine hydrochloride preconditioning provides pulmonary and systemic protection in a rat model of lung ischaemia reperfusion injury. European Journal of Pharmacology, 2018, 839: 1-11.
25. Xu F, Wang Q, Chen S, Ao H, Ma J*. The association between intraoperative dexmedetomidine and 1 year morbidity and mortality after cardiac surgery: A propensity matched analysis of over 1400 patients. J Clin Anesth. 2018, 50(11):70-75.
26. Yaguang Wang, Yafen Gao, Jun Ma. Pleiotropic effects and pharmacological properties of penehyclidine hydrochloride. Drug Design, Development and Therapy,2018, 12: 3289-3299.
27. Lin D, Cui B, Ren J, Ma J*. Regulation of VDAC1 contributes to the cardioprotective effects of penehyclidine hydrochloride during myocardial ischemia/reperfusion. Exp Cell Res. 2018, 367(2):257-263.
28. Wenjun Liu, Qian Huang, Duomao Lin, Liyun Zhao, Jun Ma*. Effect of lung protective ventilation on coronary heart disease patients undergoing lung cancer resection. J Thorac Dis 2018;10(5):2760-2770.
29. Yang Y, Ma J. High central venous pressure is associated with acute kidney injury and mortality in patients underwent cardiopulmonary bypass surgery. Journal of Critical Care, 2018, 48(10): 211-215.
30. Yang Y, Zhao L, Ma J. Penehyclidine hydrochloride preconditioning provides cardiac protection in a rat model of myocardial ischemia/reperfusion injury via the mechanism of mitochondrial dynamics mechanism. Eur J Pharmacol. 2017 Oct 15;813:130-139. doi: 10.1016/j.ejphar.2017.07.031. Epub 2017 Jul 26.
31. Tan H, Lin D, Wang Z, Yang Y, Ma J. Cardioprotective time-window of Penehyclidine hydrochloride postconditioning: A rat study. Eur J Pharmacol. 2017, 812 :48–56.
32. Hongbao Tan, Li Chen, Jun Ma. Penehyclidine hydrochloride post-conditioning reduces ischemia/reperfusion-induced cardiomyocyte apoptosis in rats. EXPERIMENTAL AND THERAPEUTIC MEDICINE. 2017, 14: 4272-4278.
33. Wenjun Liu, Duomao Lin, Sajid Ali, Jun Ma. Comparisons of two ventilation modes with lung recruitment maneuver during one-lung ventilation in patients undergoing thoracoscopic lobectomy. Biomedical Research, 2017, 28 (11): 1-6.
34. Zhaoqi Wang, Duomao Lin, Liang Zhang, Wenjun Liu, Hongbao Tan, Jun Ma. Penehyclidine Hydrochloride Prevents Anoxia/Reoxygenation Injury and Induces H9c2 Cardiomyocyte Apoptosis via A Mitochondrial Pathway. EUR J PHARMACOL, 2017, 797:115～123.
展开更多
学校介绍
首都医科大学建校于1960年，是北京市重点高等院校，著名泌尿外科专家、中国科学院院士、中国工程院院士、原全国人大常委会副委员长吴阶平教授为首任院长。学校由校本部和附属医院(即临床医学院)组成。校本部设有基础医学院、生物医学工程学院、公共卫生与家庭医学学院、高等职业教育学院、中医药学院、顺义校区、继续教育学院、护理学院、卫生事业管理与发展学院及首都医科大学国际教学部；附属医院包括宣武医院(第一临床医学院)、附属北京友谊医院(第二临床医学院)、附属北京朝阳医院(第三临床医学院)、附属北京同仁医院(第四临床医学院)、附属北京天坛医院(第五临床医学院)、附属北京安贞医院(第六临床医学院)、附属北京口腔医院(口腔医学院)、附属北京儿童医院(儿科医学院)、附属北京妇产医院(妇产医学院)、附属北京安定医院(精神卫生学院)、附属复兴医院(第八临床医学院)、附属北京中医医院(中医药临床医学院)和康复医学院。
学校和附属医院现有教职员工和医护人员22575人。有院士4人，正高职称700余人，副高职称1800余人。学校学科专业齐全，学科力量雄厚，在基础和临床各专业拥有一大批具有很高造诣的专家学者，现有3个国家级重点学科，有38个博士学位授予权学科，58个硕士学位授予权学科和2个博士后科研流动站。
校本部和附属医院总占地面积97.3万平方米，总建筑面积134万平方米 ，固定资产总值近46.5亿元，图书馆藏书108.3万册 ，住院病床10039张。学校开办的七年制专业中设有临床医学和口腔医学；五年制专业中设有临床医学、口腔医学、预防医学、护理学、中医学等；四年制专业中设有生物医学工程、中药学和康复治疗学。在临床医学专业中设有儿科医学、康复医学、医学影像、精神卫生与精神病学和医学检验5个专业方向；在生物医学工程专业中设有医学影像设备与技术和听力学专业方向。高等职业教育设有护理、医学检验、药学、医学影像技术、康复技术、口腔修复工艺、眼科验光、实验动物技术、中医学、中药制剂、医学信息、临床医学、预防医学、中药经营贸易和中医学美容专业方向15个专业。首都医科大学现已成为以培养高层次本科生与研究生为核心、以临床应用型人才为主和培养预防、康复、生物医学工程和医学基础各学科、各层次人才，位于全国先进医学院校行列的高等学府。
学校具有较强的学术发展与科研实力，在校本部和附属医院建有一批国家级和市级重点学科和重点实验室，建有高水平的国家级或市级研究和培训机构，如卫生部全科医学培训中心、临床医学研究所、基础医学研究所、神经科学研究所、眼科研究所、老年病医疗研究中心、泌尿外科研究所、心肺血管医疗研究中心、生命科学院、卫生毒理检测中心、生物工程技术研究中心、祖国医学研究所、临床疾病研究中心、中医肝病临床研究中心、生殖医学研究所、心血管疾病临床试验及社区干预中心和北京市卫生政策与卫生经济研究中心等。神经生物学、细胞生物学、电生理学、基础免疫学、实验寄生虫学、医学图像处理、生物医学、信息检测与处理、神经内科、神经外科、心脏内外科、肾移植、呼吸和消化内科、口腔颌面外科、眼科、耳鼻咽喉科、小儿血液病等领域在国内外享有较高声誉，很多学科的研究和医疗水平已经达到或接近国际先进水平。
学校十分重视对外交流与合作，改革开放以来，先后与世界20多个国家和地区签定了友好交流协议， 近十年中,先后接待美国、加拿大、英国、澳大利亚、法国、瑞典、日本、荷兰、意大利、德国、丹麦及台湾、香港和澳门等50多个国家和地区的专家学者8000余人次来校进行学术交流和参观访问。同时，学校积极选送教师、科研人员和管理干部出国进修、参加学术会议和考察访问。
展开更多