附属北京同仁医院-魏文斌导师介绍
魏文斌
主任医师
博士生导师
男
附属北京同仁医院
眼科学
眼底病临床与基础研究、眼内肿瘤发病机制与诊治研究、眼科流行病学研究、眼科人工智能研究
tr_weiwenbin@163.com
魏文斌，1965年4月出生，医学博士，现任北京同仁医院副院长、同仁眼科中心副主任，首都医科大学教授，博士研究生导师，眼科学院副院长。担任眼内肿瘤诊治研究北京市重点实验室主任、医学人工智能研究与验证工信部重点实验室主任。国家卫健委突出贡献中青年专家，享受国务院政府津贴，白求恩奖章获得者，中央保健会诊专家，获得“2020最美医生”称号。入选首批国家级和北京市新世纪“百千万”人才工程，国家特支计划工程首批领军人才。从事眼科临床工作30余年，擅长眼底病的诊断和治疗，尤其在视网膜脱离、眼内肿瘤的诊疗方面积累了丰富的经验，完成复杂性玻璃体视网膜显微手术万余例。在专业学术期刊发表SCI论文170篇，发表中文学术论文350篇，主编专著27部；授权国家专利11项。获教育部科技进步二等奖，华夏医学科技奖一等奖和二等奖，北京市科技进步奖4项，获中华医学会优秀论文一等奖和二等奖4项，承担国家自然基金等国家级和省部级科研项目共25项。现任《中华眼科杂志》《中华眼底病杂志》《眼科》《实用防盲技术杂志》副主编，《中华医学杂志英文版》、《中华实验眼科杂志》等十余种专业杂志编委。担任中华医学会眼科学分会常务委员，中华中医药学会眼科委员会常务委员，中国医师协会眼科分会常务委员兼眼底病专业委员会副主任委员，北京眼科学会会长，北京医学会眼科学分会候任主任委员。
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科研项目
研究成果
1. Dong L, Yang Q, Zhang RH, Wei WB. Artificial intelligence for the detection of age-related macular degeneration in color fundus photographs: A systematic review and meta-analysis. EClinicalMedicine. 2021 May 8;35:100875.
2. Yang JY, Wang Q, Chen MX, Yan YN, Zhou WJ, Liu YM, Wei WB. RETINAL MICROVASCULAR CHANGES IN UVEAL MELANOMA FOLLOWING CONBERCEPT INJECTION AFTER PLAQUE RADIOTHERAPY AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. Retina. 2021 Dec 1;41(12):2605-2611.
3. Dong L, Hu XY, Yan YN, Zhang Q, Zhou N, Shao L, Wang YX, Xu J, Lan YJ, Li Y, Xiong JH, Liu CX, Ge ZY, Jonas JB, Wei WB. Deep Learning-Based Estimation of Axial Length and Subfoveal Choroidal Thickness From Color Fundus Photographs. Front Cell Dev Biol. 2021;9:653692.
4. Dong L, Li YF, Jiang X, Lan YJ, Shao L, Jonas JB and Wei WB. In vivo Imaging of Retina and Choroid in Guinea Pigs. Front. Med. 8:730494.
5. Zhang H, Liu Y, Zhang K, Hui S, Feng Y, Luo J, Li Y, Wei W. Validation of the Relationship Between Iris Color and Uveal Melanoma Using Artificial Intelligence With Multiple Paths in a Large Chinese Population. Front Cell Dev Biol. 2021;9:713209.
6. Zhou N, Xu X, Wei W. Optical coherence tomography angiography characteristics of choroidal melanoma. Eye (Lond). 2021 Sep;35(9):2514-2523.
7. Du KF, Chen C, Huang XJ, Xie LY, Kong WJ, Dong HW, Wei WB. Utility of Ultra-Wide-Field Imaging for Screening of AIDS-Related Cytomegalovirus Retinitis. Ophthalmologica. 2021;244(4):334-338.
8. Luan Y, Xie B, Wei W. REST-repressed lncRNA NPPA-AS1 regulates cervical cancer progression by modulating miR-302e/DKK1/Wnt/β-catenin signaling pathway. J Cell Biochem. 2021 Jan;122(1):16-28.
9. Wang Y, Di Y, Ye J, Wei W. Study on the public psychological states and its related factors during the outbreak of coronavirus disease 2019 (COVID-19) in some regions of China. Psychol Health Med. 2021 Jan;26(1):13-22.
10. Fang R, Wang H, Li Y, Liu YM, Wei WB. Regression patterns of uveal melanoma after iodine-125 plaque brachytherapy. BMC Ophthalmol. 2021 Mar 16;21(1):137.
11. Zhou N, Zhang R, Liu Y, Wei W. Clinical Characteristics of UM and Association of Metastasis of Uveal Melanoma with Congenital Oculocutaneous Melanosis in Asian Patients: Analysis of 1151 Consecutive Eyes. Ophthalmol Retina. 2021 Nov;5(11):1164-1172.
12. Zhu J, Sainulabdeen A, Akers K, Adi V, Sims JR, Yarsky E, Yan Y, Yu Y, Ishikawa H, Leung CK, Wollstein G, Schuman JS, Wei W, Chan KC. Oral Scutellarin Treatment Ameliorates Retinal Thinning and Visual Deficits in Experimental Glaucoma. Front Med (Lausanne). 2021 Aug 3;8:681169.
13. Chen C, Du KF, Xie LY, Jiang TY, Kong WJ, Dong HW, Guo CG, Li XN, Wei WB. Clinical Features of Ocular Pathology in Patients with Acquired Immunodeficiency Syndrome and Syphilis. Adv Ther. 2021 Jun;38(6):3362-3372.
14. Du KF, Huang XJ, Chen C, Kong WJ, Xie LY, Dong HW, Wei WB. High Blood Cytomegalovirus Load Suggests Cytomegalovirus Retinitis in HIV/AIDS Patients: A Cross-Sectional Study. Ocul Immunol Inflamm. 2021 Jun 14:1-5.
15. Zhou W, Yang J, Wang Q, Wang Y, Yan Y, Wu S, Chen S, Wei W. Systemic Stressors and Retinal Microvascular Alterations in People Without Diabetes: The Kailuan Eye Study. Invest Ophthalmol Vis Sci. 2021 Feb 1;62(2):20.
16. Zhou N, Xu X, Liu Y, Wei W, Peng X. Appearance of Tumor Vessels in Patients With Choroidal Osteoma Using Swept-Source Optical Coherence Tomographic Angiography. Front Oncol. 2021 Nov 1;11:762394.
17. Zhou N, Xu X, Liu Y, Wang Y, Wei W. A proposed protocol of intravitreal injection of methotrexate for treatment of primary vitreoretinal lymphoma. Eye (Lond). 2021 Jul 1.
18. Xie LY, Chen C, Kong WJ, Jiang TY, Du KF, Dong HW, Guo CG, Li XN, Wei WB. Effect of Anti-CMV Therapy at Different Stages on Retinal Detachment in Patients with AIDS and CMVR. Adv Ther. 2021 May;38(5):2294-2301.
19. Xie Y, Xu XL, Wei WB. The RB1 Mutation Spectrum and Genetic Management Consultation in Pediatric Patients with Retinoblastoma in Beijing, China. Risk Manag Healthc Policy. 2021 Aug 21;14:3453-3463.
20. Du KF, Huang XJ, Chen C, Kong WJ, Xie LY, Wei WB. Macular Structure and Microvasculature Changes in AIDS-Related Cytomegalovirus Retinitis Using Optical Coherence Tomography Angiography. Front Med (Lausanne). 2021 Aug 13;8:696447.
21. Li HY, Liu YM, Dong L, Zhang RH, Zhou WD, Wu HT, Li YF, Wang YX, Wei WB. Global, regional, and national prevalence, disability adjusted life years, and time trends for refraction disorders, 1990-2019: findings from the global burden of disease study 2019. BMC Public Health. 2021 Sep 6;21(1):1619.
22. Xie LY, Li XN, Chen C, Kong WJ, Jiang TY, Du KF, Dong HW, Guo CG, Wei WB. Clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. Quant Imaging Med Surg. 2021 Jun;11(6):2634-2641.
23. Wang Q, Yang J, Jonas JB, Shi X, Wu S, Chen S, Yan Y, Zhou W, Dong L, Wei W, Wang YX. Prevalence of Retinal Vein Occlusions and Estimated Cerebrospinal Fluid Pressure: The Kailuan Eye Study. Eye Brain. 2021 May 21;13:147-156.
24. Wei W, Chen Y, Hu B, Zhao M, Han M, Dai H, Uy HS, Chen MY, Wang K, Jiao J, Lou J, Li XY. Multicenter, Prospective, Randomized Study of Dexamethasone Intravitreal Implant in Patients with Center-Involved Diabetic Macular Edema in the Asia-Pacific Region. Clin Ophthalmol. 2021 Oct 13;15:4097-4108.
25. Fang LJ, Dong L, Li YF, Wei WB. Retinal vein occlusion and chronic kidney disease: A meta-analysis. Eur J Ophthalmol. 2021 Jul;31(4):1945-1952.
26. Shao L, Zhou LX, Xu L, Wei WB. The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy. Sci Rep. 2021 Mar 9;11(1):5460.
27. Shao L, Zhang C, Dong L, Zhou WD, Zhang RH, Wei WB. Prevalence and Associations of Vitreomacular Traction: The Beijing Eye Study. Int J Gen Med. 2021 Oct 21;14:7059-7064.
28. Shao L, Zhang QL, Long TF, Dong L, Zhang C, Da Zhou W, Wang YX, Wei WB. Quantitative Assessment of Fundus Tessellated Density and Associated Factors in Fundus Images Using Artificial Intelligence. Transl Vis Sci Technol. 2021 Aug 2;10(9):23.
29. Xie LY, Li XN, Chen C, Kong WJ, Jiang TY, Du KF, Dong HW, Guo CG, Wei WB. Clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. Quant Imaging Med Surg. 2021 Jun;11(6):2634-2641.
30. Wang YX, Wei W Bin, Xu L, Jonas JB. Prevalence, risk factors and associated ocular diseases of cerebral stroke: the population-based Beijing Eye Study. BMJ Open. 2020;10(9):e024646.
31. Yang MC, Zhu XB, Wang YX, Wu SL, Wang Q, Yan YN, Yang X, Yang JY, Chen MX, Lei YH, Wei WB. Influencing factors for peripheral and posterior lesions in mild non-proliferative diabetic retinopathy-the Kailuan Eye Study. Int J Ophthalmol. 2020;13(9):1467-1476.
32. Wang Q, Wei WB, Wang YX, Yan YN, Yang JY, Zhou WJ, Chan SY, Xu L, Jonas JB. Thickness of individual layers at the macula and associate-d factors: the Beijing Eye Study 2011. BMC Ophthalmol. 2020;20(1):49.
33. Chen M-X, Liu Y-M, Li Y, Yang X, Wei W-B. Elevated VEGF-A & PLGF concentration in aqueous humor of patients with uveal melanoma following Iodine-125 plaque radiotherapy. Int J Ophthalmol. 2020;13(4):599-605.
34. Zhou N, Xu X, Wei W. Optical coherence tomography angiography characteristics of optic disc melanocytoma. BMC Ophthalmol. 2020;20(1):429.
35. Zhu XB, Yang MC, Wang YX, Qian W, Yan YN, Yang JY, Wu SL, Che-n SH, Dong L, Wei WB, Jonas JB. Prevalence and risk factors of epiretinalmembranes in a Chinese population: The Kailuan eye study. Investig Ophth-almol Vis Sci. 2020;61(11):6-11.
36. Zhou N, Xu X, Wei W. Analysis of clinical features of RPE adenoma. Graefes Arch Clin Exp Ophthalmol. 2020 Dec;258(12):2831-2840.
37. Li Y, Luo J-T, Liu Y-M, Wei W-B. miRNA-145/miRNA-205 inhibits proliferation and invasion of uveal melanoma cells by targeting NPR1/CDC42. Int J Ophthalmol. 2020;13(5):718-724.
38. Su Y, Xu X, Zuo P, Xia Y, Qu X, Chen Q, Guo J, Wei W, Xian J. Value of MR-based radiomics in differentiating uveal melanoma from other intraocular masses in adults. Eur J Radiol. 2020;131:109268.
39. Zhou N, Wei W, Xu X. Pathology features and the results of treatment of two cases of posterior choroidal leiomyoma. BMC Ophthalmol. 2020;20(1):198.
40. Dong L, Kang YK, Li Y, Wei W Bin, Jonas JB. PREVALENCE AND TI-ME TRENDS OF MYOPIA IN CHILDREN AND ADOLESCENTS IN CHINA: A Systemic Review and Meta-Analysis. Retina. 2020;40(3):399-411.
41. Xiao YY, Wei WB, Wang YX, Lu AD, Chen SH, Song L, Wu SL. Correlation of the history of stroke and the retinal artery occlusion: a nested case-control study. Int J Ophthalmol. 2020;13(3):431-437.
42. Qian Y, Wu Z, Chen C, Du K, Wei W. Detection of HIV-1 viral load in tears of HIV/AIDS patients. Infection. 2020 Dec;48(6):929-933.
43. Yang JY, Li Y, Wang Q, Zhou WJ, Yan YN, Wei WB. Microvascular retinal changes in pre-clinical diabetic retinopathy as detected by optical coherence tomographic angiography. Graefe’s Arch Clin Exp Ophthalmol. 2020;258(3):513-520.
44. Zhou J, Tu Y, Chen Q, Wei W. Quantitative analysis with volume rendering of pathological myopic eyes by high-resolution three-dimensional magnetic resonance imaging. Medicine (Baltimore). 2020;99(42):e22685.
45. Li YF, Dong L, Li Y, Wei W Bin. A Review of MicroRNA in Uveal Melanoma. Onco Targets Ther. 2020;13:6351-6359.
46. Jiang H, Wang S, Li Z, Xie L, Wei W, Ma J, Xian J. Improving diagnostic performance of differentiating ocular adnexal lymphoma and idiopathic orbital inflammation using intravoxel incoherent motion diffusion-weighted MRI. Eur J Radiol. 2020;130:109191.
47. Shen C, Li Y, Wang Q, Chen Y-N, Li W, Wei W-B. Choroidal vascular changes in retinitis pigmentosa patients detected by optical coherence tomography angiography. BMC Ophthalmol. 2020;20(1):384.
48. Su Y, Xu X, Wei W, Xian J. Using a novel MR imaging sign to differentiate retinal pigment epithelium from uveal melanoma. Neuroradiology. 2020;62(3):347-352.
49. Yang J-Y, Li Y, Wang Q, Zhou W-J, Yan Y-N, Wei W-B. MicroRNA-145 suppresses uveal melanoma angiogenesis and growth by targeting neuroblastoma RAS viral oncogene homolog and vascular endothelial growth factor. Chin Med J (Engl). 2020;133(16):1922-1929.
50. Dong L, Shi XH, Li YF, Jiang X, Wang YX, Lan YJ, Wu HT, Jonas JB, Wei WB. Blockade of epidermal growth factor and its receptor and axial elongation in experimental myopia. FASEB J. 2020;34(10):13654-13670.
眼底结构功能量化分析及其在心脑血管疾病的诊断、预测价值华夏医学科技奖一等奖 2020
眼部影像在全身健康评估、重大疾病预测的价值及预警体系建设高等学校科学研究优秀成果奖（科学技术）二等奖 2019
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学校介绍
首都医科大学建校于1960年，是北京市重点高等院校，著名泌尿外科专家、中国科学院院士、中国工程院院士、原全国人大常委会副委员长吴阶平教授为首任院长。学校由校本部和附属医院(即临床医学院)组成。校本部设有基础医学院、生物医学工程学院、公共卫生与家庭医学学院、高等职业教育学院、中医药学院、顺义校区、继续教育学院、护理学院、卫生事业管理与发展学院及首都医科大学国际教学部；附属医院包括宣武医院(第一临床医学院)、附属北京友谊医院(第二临床医学院)、附属北京朝阳医院(第三临床医学院)、附属北京同仁医院(第四临床医学院)、附属北京天坛医院(第五临床医学院)、附属北京安贞医院(第六临床医学院)、附属北京口腔医院(口腔医学院)、附属北京儿童医院(儿科医学院)、附属北京妇产医院(妇产医学院)、附属北京安定医院(精神卫生学院)、附属复兴医院(第八临床医学院)、附属北京中医医院(中医药临床医学院)和康复医学院。
学校和附属医院现有教职员工和医护人员22575人。有院士4人，正高职称700余人，副高职称1800余人。学校学科专业齐全，学科力量雄厚，在基础和临床各专业拥有一大批具有很高造诣的专家学者，现有3个国家级重点学科，有38个博士学位授予权学科，58个硕士学位授予权学科和2个博士后科研流动站。
校本部和附属医院总占地面积97.3万平方米，总建筑面积134万平方米 ，固定资产总值近46.5亿元，图书馆藏书108.3万册 ，住院病床10039张。学校开办的七年制专业中设有临床医学和口腔医学；五年制专业中设有临床医学、口腔医学、预防医学、护理学、中医学等；四年制专业中设有生物医学工程、中药学和康复治疗学。在临床医学专业中设有儿科医学、康复医学、医学影像、精神卫生与精神病学和医学检验5个专业方向；在生物医学工程专业中设有医学影像设备与技术和听力学专业方向。高等职业教育设有护理、医学检验、药学、医学影像技术、康复技术、口腔修复工艺、眼科验光、实验动物技术、中医学、中药制剂、医学信息、临床医学、预防医学、中药经营贸易和中医学美容专业方向15个专业。首都医科大学现已成为以培养高层次本科生与研究生为核心、以临床应用型人才为主和培养预防、康复、生物医学工程和医学基础各学科、各层次人才，位于全国先进医学院校行列的高等学府。
学校具有较强的学术发展与科研实力，在校本部和附属医院建有一批国家级和市级重点学科和重点实验室，建有高水平的国家级或市级研究和培训机构，如卫生部全科医学培训中心、临床医学研究所、基础医学研究所、神经科学研究所、眼科研究所、老年病医疗研究中心、泌尿外科研究所、心肺血管医疗研究中心、生命科学院、卫生毒理检测中心、生物工程技术研究中心、祖国医学研究所、临床疾病研究中心、中医肝病临床研究中心、生殖医学研究所、心血管疾病临床试验及社区干预中心和北京市卫生政策与卫生经济研究中心等。神经生物学、细胞生物学、电生理学、基础免疫学、实验寄生虫学、医学图像处理、生物医学、信息检测与处理、神经内科、神经外科、心脏内外科、肾移植、呼吸和消化内科、口腔颌面外科、眼科、耳鼻咽喉科、小儿血液病等领域在国内外享有较高声誉，很多学科的研究和医疗水平已经达到或接近国际先进水平。
学校十分重视对外交流与合作，改革开放以来，先后与世界20多个国家和地区签定了友好交流协议， 近十年中,先后接待美国、加拿大、英国、澳大利亚、法国、瑞典、日本、荷兰、意大利、德国、丹麦及台湾、香港和澳门等50多个国家和地区的专家学者8000余人次来校进行学术交流和参观访问。同时，学校积极选送教师、科研人员和管理干部出国进修、参加学术会议和考察访问。
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