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曹光磊,男,50岁,北京积水潭医院保膝外科主任医师,教授,博士研究生导师
中国老年保健协会骨关节保护与健康分会秘书长,ZBI讲师,担任Orthopaedic Surgery, BMC musculoskeletal disorders, 中华外科杂志,实用骨科杂志等期刊的特约审稿人
专业方向:老年膝骨关节炎的微创保膝治疗;髋膝关节置换及翻修手术
曾于2006年及2009年分别赴新加坡中央医院和加拿大西安大略大学医院进修髋、膝关节膝关节置换术,2017年赴英国纳菲尔德医学中心学习牛津单髁置换术,目前正致力于推广膝关节骨关节炎阶梯化治疗的“保膝”理念。
完成膝关节置换手术数千例,其中单髁置换术1000余例,围膝关节周围截骨术300余例,初次髋、膝关节置换3000余例。
课题名称 | 级别 | 项目来源 |
盐酸氯苯哌酮对髋/膝关节置换术后镇痛效果的探索及群体药代动力学研究 | 国家级 | 临床多中心IIa期药物试验 |
长链非编码RNA LINC00323在低氧环境中调控骨折愈合分子机制的研究 | 省部级 | 北京市自然科学基金面上项目 |
老年卒中后髋部骨折的外科治疗研究 | 省部级 | 首都临床特色应用研究 |
人工关节置换术围手术期血液管理相关研究 | 市局级 | 北京市科技计划项目 |
补肾活血方对双平面开放楔形胫骨高位截骨术后骨愈合影响的研究 | 市局级 | 首都卫生发展专项 |
计算机头部控制与颈椎辅助康复系统研究 | 校局级 | 首都医科大学基础临床课题 |
应用便携式步态能量分析仪进行TKA术后步态分析 | 校局级 | 首都医科大学基础临床课题合作基金 |
骨科手术导航定位系统在全膝关节置换术中的安全性和有效性研究 | 横向 | 北京天智航医疗科技股份有限公司 |
UKA和HTO治疗中国人群前内侧骨关节炎的早期临床结果研究 | 横向 | 捷迈(上海)医疗国际贸易有限公司 |
评价骨科导航定位系统辅助进行膝关节单髁置换的有效性和安全性试验 | 横向 | 杭州键嘉医疗科技股份有限公司 |
在本专业方向以第一或通讯作者身份发表核心期刊31篇,SCI文章32篇。
作为编者出版书籍3本。获国家专利4项。
主持国家级课题1项,省部级课题2项,局级课题2项,校局级科研项目2项,参与973支撑课题、国家自然科学基金课题、北京市科委计划课题等多项相关课题,曾获得教育部科学技术进步一等奖。
以下是曹光磊教授为第一作者或通讯作者发表的主要英文文章:
1.Xufeng, Jiao., Yunfei, Jiang., Zheng, Li., Shuai, An., Jiang, Huang., Guanglei, Cao (2023). In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty. J Vis Exp, 0(195), 0. doi:10.3791/64993
2.Tianlang, Xie., Xufeng, Jiao., Xiaomei, Yao., Zheng, Li., Shuai, An., Guanglei, Cao*.(2023). How much the leg length has changed after the MOUKA through measurement of the full length radiographs? Beware of splicing error. BMC Musculoskelet Disord, 24(1), 0. doi:10.1186/s12891-023-06472-0
3.Jiangpeng, Wu., Zheng, Li., Jiang, Huang., Xufeng, Jiao., Guanglei, Cao*.(2023). Staged open reduction and internal fixation with double-locking plates to treat bilateral distal femur periprosthetic fractures after total knee arthroplasty: A case report. Front Surg, 9(0), 0. doi:10.3389/fsurg.2022.987953
4. Xufeng, Jiao., Zheng, Li., Mincong, Du., Shuai, An., Jiang, Huang., Guanglei, Cao*.(2023). Valgus Stress Radiograph Can Predict Alignment Change of Medial Mobile-Bearing Unicompartmental Knee Arthroplasty. Orthop Surg, 15(7), 0. doi:10.1111/os.13823
5. Xufeng, Jiao., Guanglei, Cao*., Jiangpeng, Wu., Zheng, Li., Shuai, An., Jiang, Huang (2023). Assessing lateral femoral condyle cartilage prior to medial UKA: MRI vs. Valgus stress radiograph. BMC Musculoskelet Disord, 24(1), 0. doi:10.1186/s12891 -023- 06802-2
6. Shuai, An., Jingfei, Shi., Jiang, Huang., Zheng, Li., Mingli, Feng., Guanglei, Cao*.(2023). HIF-1α-induced upregulation of m6A reader IGF2BP1 facilitates peripheral nerve injury recovery by enhancing SLC7A11 mRNA stabilization. In Vitro Cell Dev Biol Anim, 59(8), 0. doi:10.1007/s11626-023-00812-z
7. Xufeng, Jiao., Zheng, Li., Shuai, An., Jiang, Huang., Mingli, Feng., Guanglei, Cao*.(2022). Does diabetes mellitus increase the incidence of early thrombosis in deep vein following unicompartmental knee arthroplasty: a retrospective cohort study. BMC Geriatr, 22(1), 0. doi:10.1186/s12877-022-03153-w.
8. Xufeng, Jiao., Shuai, An., Guanglei, Cao*., Zheng, Li., Mingli, Feng., Jiang, Huang.(2021). Slight cartilage damage in weight-bearing area of lateral femoral condyle do not compromise short-term outcomes of medial unicompartmental knee arthroplasty. Arch Orthop Trauma Surg, 142(12), 0. doi:10.1007/s00402-021-04254-8
9. Guangzhong, Yang., Xufeng, Jiao., Qianli, Li., Zheng, Li., Shuai, An., Mingli, Feng., Guanghan, Gao., Jiang, Huang., Guanglei, Cao*.(2021). Hybrid Oxford unicompartmental knee arthroplasty has lower residual cement extrusion than cemented arthroplasty in treating end-stage unicompartmental knee osteoarthritis. BMC Musculoskelet Disord, 22(1), 0. doi:10.1186/s12891 -021-04720-9
10. Guanghan, Gao., Zheng, Li., Yannong, Wang., Guangzhong, Yang., Jiang, Huang., Shuai, An., Junjie, Qiao., Guanglei, Cao*.(2020). Effect of vertical cut on coronal coverage and rotation of tibial component in Oxford unicompartmental knee arthroplasty. J Int Med Res, 48(5), 0. doi:10.1177/0300060520922426
11. Xufeng, Jiao., Zheng, Li., Shuai, An., Jiang, Huang., Guangzhong, Yang., Yi, Zhao.,
Jianghua, Shen., Yanqi, Chu., Charlie C, Yang., Guanglei, Cao*.(2020). An elderly female with adult-onset Still's disease initially misdiagnosed as prosthetic joint infection after total knee arthroplasty: lessons in differential diagnosis and treatment. BMC Geriatr,20(1), 0.
12. Li Zheng., Wang Yannong., Cao Guanglei*., An Shuai., Feng Mingli., Wang Liwei., Wang Xi., Yang Guangzhong., Gao Guanghan., Wang Shuai., Jiao Xufeng., Ding
Lei.(2020). Does the correction angle affect hidden blood loss in HTO? J Orthop Surg Res, 15(1), 528. doi:10.1186/s13018-020-02071-0.
13.Qiao J, Zhou M, Li Z, Ren J, Gao G, Zhen J, Cao G, Ding L.Elevated serum granzyme B levels are associated with disease activity and joint damage in patients with rheumatoid arthritis. J Int Med Res.2020;48(11):300060520962954.
14.Junjie Qiao Meng Zhou Zheng Li Jie Ren Guanghan Gao Guanglei Cao Huiliang Shen Shibao Lu Comparison of remote ischemic preconditioning and intermittent hypoxia
training in fracture healing Mol Med Rep. 2019. 19(3) 1867-1874
15.Junjie Qiao 1, Jiang Huang 1, Meng Zhou 1, Guanglei Cao 1, Huiliang Shen 1
Inhibition of HIF-1α restrains fracture healing via regulation of autophagy in a rat model Exp Ther Med. 2019 Mar;17(3):1884-1890
16.Meng Zhou 1, Shuai An 2, Mingli Feng 3, Zheng Li 4, Huiliang Shen 5, Kuan Zhang 6, Jun Sun 7, Guanglei Cao 8 Gait analysis of patients with continuous proximal sciatic nerve blockade in flexion contractures after primary total knee arthroplasty Gait & Posture .2018. 66166-171
17.Guang-Lei Cao, Jun-Lin Zhou 1, Hui-Liang Shen, Meng Zhou Application of continuous proximal sciatic nerve blockade in the treatment of flexion contractures after primary total knee arthroplasty Chin Med J .2015. 128(8) 1134-1136,
18.Jiang Huang, Hui-liang Shen, Shi-bao Lu, Ming-li Feng, Zheng Li, Shuai An, Guang- lei Cao*.Induction of lncRNA MALAT1 by hypoxia promotes bone formation by regulating the miR-22-3p/CEBPD axis.[J]. Int J Mol Med
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