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刘利强，首都医科大学宣武医院神经病学博士，美国匹兹堡大学医学中心访问学者，博士后。现为北京脑重大疾病研究院副研究员、首都医科大学宣武医院副主任医师、北京高原适应研究康复中心副主任医师。主持“十四五”国家重点研发计划项目课题“脑血管病及危险因素监测技术应用模式探索”研究，重点参与宣武医院亚低温和间歇性低氧脑保护基础和临床研究，在低温和间歇性低氧脑保护领域有深入的研究，撰写的低温脑保护相关论文发表在国际脑血管病知名期刊《Stroke》等杂志，参与国家自然科学基金项目“亚低温对缺血性脑损伤microRNA表达谱的影响及机制研究”、“基于靶向低温的脑损伤神经保护系统研制”和军委后勤保障部项目“高原低压缺氧、寒冷冷复合环境创伤失血休克特点及损失控制策略”。成果陆续发表于Stroke、JCBFM、CNSNeuro & Therapeutic等期刊，在 SCI期刊和中文核心期刊发表论文20余篇，获省部级医学科技奖2项。
国家重点研发计划项目课题：“脑血管病及危险因素监测技术应用模式探索”，202311-202610 。
发表论文
1、Liu L, Liu J, Li M, LyuJ, Su W, Feng S, Ji X. Selective brain hypothermia attenuates focal cerebralischemic injury and improves long-term neurological outcome in aged femalemice. CNS Neurosci Ther. 2023 Jan;29(1):129-139.
2、Liu L*, Liu X*, Zhao J,Yan F, Wang R, Wen S, Wang L, Luo Y, Ji X. Brain‐selective mild hypothermiapromotes long‐term white matter integrity after ischemic stroke in mice. CNSNeurosci Ther. 2018; 24(12): 1275-1285
3、Liu L, Liu X,Wang R, Yan F, Luo Y, Chandra A, Ding Y, Ji X. Mild focal hypothermia regulatesthe dynamic polarization of microglia after ischemic stroke in mice. Neurol Res. 2018; 40(6):508-515.
4、Chen J*, Liu L*,Zhang H, Geng X, Jiao L, Li G, Coutinho JM, Ding Y, Liebeskind DS, Ji X.Endovascular hypothermia in acute ischemic stroke: Pilot study ofselective Intra-Arterial cold saline infusion. Stroke. 2016; 47: 1933-1935.
5、Peij, Liu L, Pang J, Tian X. Hyperlipidemia affects neuronal nitric oxidesynthase expression in brains of focal cerebral ischemia rat model. Neural Regen Res, 2008, 6: 642-646
6、Zhao J,Mu H, Liu L, Jiang X, Wu D, Shi Y, Leak RK, Ji X. Transientselective brain cooling confers neurovascular and functionalprotection from acute to chronic stages of ischemia/reperfusionbrain injury. Journal of Cerebral Blood Flow & Metabolism. 2019;39(7): 1215-1231.
7、Shi L,Rocha M, Zhang W, Jiang M, Li S, Ye Q, Hassan SH, Liu L, Adair MN, Xu J,Luo J, Hu X, Wechsler LR, Chen J, Shi Y. Genome-widetranscriptomic analysis of microglia reveals impaired responses in aged miceafter cerebral ischemia. Journal of Cerebral Blood Flow & Metabolism. 2020 May 21.
8、Liu X, Wen S, Yan F, Liu K, LiuL, Wang L, Zhao S, Ji X. Salidroside provides neuroprotection bymodulating microglial polarization after cerebral ischemia. Journal of Neuroinflammation. 2018 Feb 9;15(1):39
9、Wu C, Zhao W, An H, Wu L, ChenJ, Hussain M, Ding Y, Li C, Wei W, Duan J, Wang C, Yang Q, Wu D, Liu L,Ji X. Safety, feasibility, and potential efficacy of intraarterialselective cooling infusion for stroke patients treated with mechanicalthrombectomy. Journal of Cerebral Blood Flow & Metabolism. 2018; 38(12):2251-2260.
10、刘利强, 罗玉敏, 吉训明. 低温治疗急性脑梗死的临床研究进展. 中国脑血管病杂志，2015,06:325-329
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