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首都医科大学宣武医院神经内科主治医师，北京市杰出青年科学基金获得者、北京脑重大疾病研究院兼职学术骨干、北京市科技新星、首都医科大学优秀青年人才，兼任中国老年医学学会脑血管病分会青年副主任委员、国际血管联盟中国分部脑血管疾病专家委员会常务委员等。
以第一和通讯作者（含共同）在Circulation、Cochrane Database of Systematic Reviews、Stroke、Hypertension、JCBFM等期刊发表SCI论文27篇，被JAMA，Nature Reviews Neurology等期刊累计引用1400余次。受邀在Stroke杂志进行成果报道；在JAMA Neurology、Brain、Stroke杂志撰写评论和观点文章。作为项目骨干参与BAOCHE和RICA两项全国多中心临床研究，并作为主要作者之一在The New England Journalof Medicine和Lancet Neurology发表研究成果。执笔起草美国适应医学会临床指南——Clinical PracticeGuidelines of Remote Ischemic Conditioning for the Management of CerebrovascularDiseases和国家“百万减残工程”专家委员会临床共识——《远隔缺血适应防治缺血性脑血管病中国专家共识》。
1. 国家自然科学基金委青年项目《GAS6/AXL通路介导的小胶质细胞/巨噬细胞胞葬在远隔缺血适应促进脑出血后血肿清除中的作用及机制研究》。
2. 北京市自然基金委杰出青年科学基金项目《急性缺血性卒中血管再通后微循环障碍机制及干预策略研究》
3. 北京市科技新星计划项目《远隔缺血适应联合机械取栓治疗急性缺血性卒中的有效性研究》
4. 首都医科大学优秀青年人才项目《缺血性卒中血流再灌注障碍研究》
5. 北京市教育委员会科技计划一般项目《远隔缺血适应促进脑出血后血肿清除中的作用机制研究》
围绕缺血性卒中血管再通和脑保护治疗相关难题，①提出了缺血性卒中内源性神经保护新方法，证实其在缺血性卒中防治中的作用，成果写入国际指南；②优化了缺血性卒中血管再通治疗方案，提高血管再通率，改善神经功能预后，成果被中国专家共识推荐应用；③建立了缺血性卒中“血管再通基础上多阶段、序贯脑保护”治疗新策略，被国际同行认可和采纳。
发表论文：
1. Zhao Wenbo, Meng Ran, Ma Chun, Hou Baojun, Jiao Liqun, ZhuFengshui, Wu Weijuan, Shi Jingfei, Duan Yunxia, Zhang Renling, Zhang Jing, SunYongxin, Zhang Hongqi, Ling Feng, Wang Yuping, Feng Wuwei, Ding Yuchuan,Ovbiagele Bruce, Ji Xunming*. Safety and Efficacy of Remote IschemicPreconditioning in Patients With Severe Carotid Artery Stenosis Before CarotidArtery Stenting: A Proof-of-Concept, Randomized Controlled Trial. Circulation,2017, 135(14): 1325-1335.（JCR: 1区）
2. Zhao Wenbo#, Che Ruiwen#,Shang Shuyi#, Wu Chuanjie, Li Chuanhui, Wu Longfei, Chen Jian, DuanJiangang, Song Haiqing, Zhang Hongqi, Ling Feng, Wang Yuping, Liebeskind David,Feng Wuwei, Ji Xunming*. Low-Dose Tirofiban Improves Functional Outcome inAcute Ischemic Stroke Patients Treated With Endovascular Thrombectomy. Stroke,2017, 48(12): 3289-3294.（JCR: 1区）
3. Zhao Wenbo, Jiang Fang, Zhang Zhen, Zhang Jing, Ding Yuchuan, Ji Xunming*. RemoteIschemic Conditioning: A Novel Non-Invasive Approach to Prevent Post-StrokeDepression. Frontiers in Aging Neuroscience, 2017, 9: 270.（JCR: 2区）
4. Zhao Wenbo, Zhang Jing, Sadowsky Mordechai G, Meng Ran, Ding Yuchuan, Ji Xunming*.Remote ischaemic conditioning for preventing and treating ischaemic stroke.Cochrane Database Syst Rev, 2018, 7: CD012503. （JCR: 1区）
5. Zhao Wenbo, Che Ruiwen, Li Sijie, Ren Changhong, Li Chuanhui, Wu Chuanjie, Lu Hui,Chen Jian, Duan Jiangang, Meng Ran, Ji Xunming*. Remote ischemic conditioningfor acute stroke patients treated with thrombectomy. Ann Clin Transl Neurol,2018, 5(7): 850-856.（JCR: 1区）
6. Zhao Wenbo#, Li Sijie#, Ren Changhong, Meng Ran, JiXunming*. Chronic Remote Ischemic Conditioning May Mimic Regular Exercise: Perspectivefrom Clinical Studies. Aging and disease, 2018, 9(1): 165-171.（JCR: 1区）
7. Zhao Wenbo, Shang Shuyi, Li Chuanhui, Wu Longfei, Wu Chuanjie, Chen Jian, SongHaiqing, Zhang Hongqi, Zhang Yunzhou, Duan Jiangang*, Feng Wuwei, Ji Xunming*.Long-term outcomes of acute ischemic stroke patients treated with endovascularthrombectomy: A real-world experience. Journal of the Neurological Sciences,2018, 390: 77-83.（JCR: 2区）
8. Zhao Wenbo, Zhang Jing, Sadowsky Mordechai, Meng Ran, Ding Yuchuan, Ji Xunming*.Remote Ischemic Conditioning for Preventing and Treating Ischemic Stroke. Stroke,2018, 49(12): e327-e328.（JCR: 1区）
9. Zhao Wenbo, Zhang Jing, Chen Jian, Song Haiqing, Ji Xunming*. Net water uptake: a newtool for the assessment of ischaemic stroke oedema. Brain 2019, 142(7):e34.（JCR: 1区）
10. Zhao Wenbo, Li Sijie, Ren Changhong, Meng Ran, Jin Kunlin, Ji Xunming*. Remoteischemic conditioning for stroke: clinical data, challenges, and futuredirections. Ann Clin Transl Neurol, 2019, 6(1): 186-196.（JCR: 1区）
11. An Hong#, Zhao Wenbo#,Wang Jianguo, Wright Joshua C, Elmadhoun Omar, Wu Di, Shang Shuyi, Wu Chuanjie,Li Chuanhui, Wu Longfei, Chen Jian, Duan Jiangang, Zhang Hongqi, Song Haiqing,Ding Yuchuan, Ji Xunming*. Contrast Staining may be Associated withIntracerebral Hemorrhage but Not Functional Outcome in Acute Ischemic StrokePatients Treated with Endovascular Thrombectomy. Aging and disease,2019, 10(4): 784-792.（JCR: 1区）
12. Wu Longfei#, Zhao Wenbo#,Rajah Gary B, Wu Di, Chen Jian, Zhang Zhen, Wu Chuanjie, Li Chuanhui, DuanJiangang, An Hong, Che Ruiwen, Jiang Fang, Ding Yuchuan, Ji Xunming*.Postinterventional Sedation Worsens Functional Outcomes in Patients with AcuteIschemic Stroke Treated with Endovascular Therapy. World neurosurgery,2019, 130: e794-e803.（JCR: 4区）
13. Jiang Fang#, Zhao Wenbo#,Wu Chuanjie, Zhang Zhen, Li Chuanhui, Che Ruiwen, Chen Jian, Hu Weiming, SongHaiqing, Duan Jiangang, Ji Xunming*. Asymptomatic Intracerebral Hemorrhage MayWorsen Clinical Outcomes in Acute Ischemic Stroke Patients UndergoingThrombectomy. Journal of Stroke and Cerebrovascular Diseases, 2019,28(6): 1752-1758.（JCR: 4区）
14. Zhao Wenbo, Wu Chuanjie, Dornbos III David, Li Sijie, Song Haiqing, Wang Yuping, DingYuchuan, Ji Xunming*. Multiphase adjuvant neuroprotection: A novel paradigm forimproving acute ischemic stroke outcomes. Brain Circulation, 2020, 6(1):11-18.
15. Zhao Wenbo, Ren Changhong, Ji Xunming*. Remote Ischemic Perconditioning for theTreatment of Acute Ischemic Stroke. JAMA Neurol 2020, 77(11): 1451-1452.（JCR: 1区）
16. Zhao Wenbo, Wu Chuanjie, Stone Christopher, Ding Yuchuan, JiXunming*. Treatment of intracerebral hemorrhage: Currentapproaches and future directions. Journal of the Neurological Sciences,2020, 416: 117020.（JCR: 2区）
17. Zhao Wenbo, Jiang Fang, Li Sijie, Wu Chuanjie, Gu Fei, ZhangQuanzhong, Gao Xinjing, Gao Zongen, Song Haiqing, Wang Yuping, Ji Xunming*. RemoteIschemic Conditioning for Intracerebral Hemorrhage (RICH-1): Rationale andStudy Protocol for a Pilot Open-Label Randomized Controlled Trial. FrontNeurol, 2020, 11: 313.（JCR: 2）
18. Zhao Wenbo#*, XuJiali#, Li Sijie, Liu Guiyou, Wu Longfei, Li Chuanhui, WuChuanjie, Ren Changhong, Chen Jian, Duan Jiangang, Wang Ruixian, Song Haiqing,Ma Qingfeng, Ji Xunming*. Low-dose tirofiban is associated with reducedin-hospital mortality in cardioembolic stroke patients treated withendovascular thrombectomy. J Neurol Sci, 2021, 427: 117539.（JCR: 2区）
19. Zhao Wenbo#, LiuRan#, Yu Wantong, Wu Longfei, Wu Chuanjie, Li Chuanhui,Li Sijie, Chen Jian, Song Haiqing, Hua Yang*, MaQingfeng*, Ji Xunming*.Elevated pulsatility index is associated with poor functional outcome in strokepatients treated with thrombectomy: A retrospective cohort study. CNSNeurosci Ther. 2022, 28(10):1568-1575. （JCR: 1区）
20. Wang Xian, Wang Xiaoyin, Ma Jin, Jia Milan, WuLongfei, Li Weili, Li Chuanhui, Wu Chuanjie, Ren Changhong, Chen Xin, ZhaoWenbo*, Ji Xunming*.Association between the time of day at stroke onset and functional outcome ofacute ischemic stroke patients treated with endovascular therapy. J CerebrBlood F Met, 2022;42(12):2191-2200.（JCR: 1区）
21. Ma Jin, Guo Wenting, Xu Jiali, Li Sijie, RenChanghong, Wu Longfei, Wu Chuanjie, Li Chuanhui, Chen Jian, Duan Jiangang, MaQingfeng, Song Haiqing, ZhaoWenbo*, Ji Xunming*. Association of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyteratio with outcomes in stroke patients achieving successful recanalization byendovascular thrombectomy. Frontiers in neurology. 2022;13:1039060.（JCR: 2区）
22. Zhao Wenbo#, JiangFang#, Li Sijie, Liu Guiyou, Wu Chuanjie, Wang Yuang,Ren Changhong, Zhang Jing, Gu Fei, Zhang Quanzhong, Gao Xinjing, Gao Zongen,Song Haiqing, Ma Qingfeng, Ding Yuchuan*, Ji Xunming, RICH-1 Investigators;Safety and efficacy of remote ischemic conditioning for the treatment ofintracerebral hemorrhage: A proof-of-concept randomized controlled trial. IntJ Stroke. 2022;17(4):425-433.（JCR: 1区）
23. Guo Wenting, Zhao Wenbo*, Li Dong, JiaHaiying, Ren Changhong, Li Sijie, Zhao Jing, Yu Bingxin, Dong Jian, Guo Rongfen,Zhu Kun, Gao Yu, Wang Yan, Wang Ying, Li Zunshan, Wang Zhen, Wang Dan, HouChengbei, Derek Hausenloy, Chu Xi*, Ji Xumming*; Chronicremote ischemic conditioning in patients with mild hypertension in the absenceof antihypertensive medication: a multicenter, randomized, double-blind,proof-of-concept clinical trial. Hypertension, 2023;80(6):1274-1282.（JCR: 1区）
24. Jiali Xu, Wenting Guo, Jin Ma, Qingfeng Ma, JianChen, Haiqing Song, Changhong Ren, Sijie Li, Yuchuan Ding, Wenbo Zhao*,and Xunming Ji; Preceding transient ischemic attack wasassociated with functional outcome after stroke thrombectomy: A propensityscore matching study. J CerebrBlood F Met, 2023;43(8):1390-1399.（JCR: 1区）
25. Wenbo Zhao, Derek J. Hausenloy, David C. Hess, Derek M. Yellon, Xunming Ji. RemoteIschemic Conditioning: Challenges and Opportunities. Stroke, 2023;54(8):2204-2207.（JCR: 1区）
26. Longfei Wu, Ming Wei, Bohao Zhang, et al. WenboZhao*, Xunming Ji. Safety and Tolerability of Direct Ischemic Post-conditioningfollowing Thrombectomy for Acute Ischemic Stroke. Stroke, 2023 ;54(9):2442-2445.（JCR: 1区）
27. Wenting Guo, Ning Li, Jiali Xu, Jin Ma, Sijie Li,Changhong Ren, Jian Chen, Jiangang Duan, Qingfeng Ma, Haiqing Song, WenboZhao*, Xunming Ji; Malignant middle cerebral artery infarction during earlyversus late endovascular treatment in acute ischemic stroke.Currentneurovascular research 2023.（JCR: 4区）
28. 赵文博,李思颉,吉训明.《远隔缺血适应防治缺血性脑血管病中国专家共识》解读[J].中国脑血管病杂志,2021,18(9):585-589.DOI:10.3969/j.issn.1672-5921.2021.09.001.
29. 赵文博,车睿雯,张婧,段建钢,陈健,吉训明.基于血管再通的神经保护治疗临床研究进展[J].中国脑血管病杂志,2017,14(10):540-545.DOI:10.3969/j.issn.1672-5921.2017.10.009.
30. 赵文博,孟然,张婧,吉训明.颈动脉支架置入术相关亚临床性栓塞的研究进展[J].中国脑血管病杂志,2016,13(6):332-336.DOI:10.3969/j.issn.1672-5921.2016.06.013.
31. 国家“百万减残工程”规范指导临床办公室,中国老年医学学会脑血管病分会.远隔缺血适应防治缺血性脑血管病中国专家共识[J].中华医学杂志,2021,101(25):1953-1967.DOI:10.3760/cma.j.cn112137-20210122-00213.
1. 国家科学技术进步奖二等奖《低氧与缺血适应防治缺血性脑卒中新技术体系的创研及推广应用》
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3. 首都医科大学宣武医院青年科技成果奖《缺血性脑血管病血管再通治疗预后及新技术研发》
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