我们的主要研究方向是，在脑血管病中炎症相关引起的神经损伤机制以及神经细胞死亡方式。

主持或参加科研项目：

1. 国家自然科学基金青年项目，82001243，蛋白酶NE调控Gadd45γ在脑小血管病白质病变中对少突胶质细胞的损伤作用研究，2021/01-2023/12，24万元，在研，主持

2. 国家自然科学基金面上项目，81871021，IL4I1调控少突胶质祖细胞分化参与毛柳甙保护缺血性脑损伤的髓鞘再生机制，2019/01-2022/12，56万元，在研，参加

3. 国家自然科学基金面上项目，81870821，靶向小胶质细胞CSF1R的嵌合抗原受体T细胞免疫疗法在阿尔兹海默病中作用机制探索，2019/01-2022/12，56万元，在研，参加

(1) Dong, Cheng-Ya; Wen,Shao-Hong; Zhao, Shun-Ying; Sun, Si; Zhao, Shang-Feng; Dong, Wen; Han,Ping-Xin; Chen, Qing-Fang; Gong, Ting; Chen, Wen-Tao; Liu, Wen-Qian; Liu,Xiang-Rong*; Salidroside Inhibits Reactive Astrogliosis and Glial ScarFormation in Late Cerebral Ischemia via the Akt/GSK-3β Pathway., NeurochemicalResearch, 2021, 46(4): 755-769. (期刊论文)

(2) Dong, Cheng-Ya*; Yuan, Zheng-Rong; Li, Qi; Wang, Ya-Jie*; The clinicopathological and prognosticsignificance of TP53 alteration in K27M mutated gliomas: anindividual-participant data meta-analysis, NeurologicalSciences, 2018, 39(7): 1191-1201. (期刊论文)

(3) Dong, Cheng-Ya; Cui, Jia-Yue;Li, Dian-He; Li, Qi*; Hong,Xin-Yu*; HOXA10‑AS: A novel oncogenic long non‑coding RNA in glioma, OncologyReports, 2018, 4 0(5): 2573-2583. (期刊论文)

(4) Li Qi*;Dong, Cheng-Ya; Cui, Jia-Yue; Wang, Yu-Bo; Hong, Xin-Yu*. Over-expressed lncRNA HOTAIRM1 promotestumor growth and invasion through up-regulating HOXA1 and sequestering G9a awayfrom the HOXA1 gene in glioblastoma multiforme, Journal of Experimental andClinical Cancer Research, 2018 37(1):265. (期刊论文)

(5) Li Qi*;Li Bai; Dong, Cheng-Ya; Wang, Ya-Jie. 20(S)-Ginsenoside Rh2suppresses proliferation and migration of hepatocellular carcinoma cells bytargeting EZH2 to regulate CDKN2A-2B gene cluster transcription, EuropeanJournal of Pharmacology, 2017 815:173-180. (期刊论文)

(7) Dong, Cheng-Ya; Liu, Xiao-Yan;Wang, Nan; Wang, Li-Na; Yang, Bin-Xia; Ren, Qian; Liang, Hao-Yue; Ma, Xiao-Tong*; Twist-1, a novel regulator ofhematopoietic stem cell self-renewal and myeloid lineage development., Stem Cells, 2014, 32(12): 3173-3182. (期刊论文)

(8) Dong, Cheng-Ya#; Zhang, Fang#; Duan, Yong-Juan;Yang, Bin-Xia; Lin, Yong-Min; Ma, Xiao-Tong*; mda-7/IL-24 inhibits the proliferation ofhematopoietic malignancies in vitro and in vivo., Experimental Hematology, 2008, 36(8):938-946. (期刊论文)