（1） 基于生物参数特征和遗传信息构建高危类型原发性闭角型青光眼的精准化个性化诊疗规范，范志刚，国家自然科学基金面上项目，82471072，2025.1-2028.12，70万元。

（2） 比较不同眼压设置的白内障手术治疗原发性闭角型青光眼（PACG）术后前房炎症反应的差异：一项前瞻性随机对照研究，范志刚，企业委托横向项目，2023.1-2024.1，40.767万

（3） 新型多通道房水引流术治疗中青年晚期原发性开角型青光眼的疗效及机制研究，范志刚，首都临床特色诊疗技术研究及转化应用，Z221100007422057, 2022.11-2025.12，35万

（4） MYRF基因突变在真性小眼球继发闭角型青光眼晶状体悬韧带病变中的作用和机制研究，范志刚，国家自然科学基金面上项目，82171050，2022.01-2025.12，54万

1. Yu XW, Li ZJ, Lin DT, Gao Y, Tian JX, Fan ZG, Shi Y. Alterations of the vitreous pathology and anterior chamber angle structures following transscleral cyclophotocoagulation. Int J Ophthalmol. 2025 Dec 18;18(12):2246-2254. doi: 10.18240/ijo.2025.12.04. PMID: 41280620; PMCID: PMC12635812.

2. Gao Y, Shi Y, Yu X, Zhong H, Mei F, Pei X, Wang S, Fan Z. Peripheral vitreoretinal abnormality and its correlation with malignant glaucoma in nanophthalmos with secondary angle closure glaucoma. Eye (Lond). 2025 Sep 10. doi: 10.1038/s41433-025-03984-y. Epub ahead of print. PMID: 40931033.

3. Shi Y, He X, Liu W, Hu J, Qiu WQ, Zhang X, Fan Z. Associations of diabetes mellitus with primary open angle glaucoma and Alzheimer's disease: a large cohort study in UK biobank. Front Endocrinol (Lausanne). 2025 Jul 24;16:1506560. doi: 10.3389/fendo.2025.1506560. PMID: 40778276; PMCID: PMC12328150.

4. Yu X, Zhao H, Gao Y, Zhou T, Deng L, Zhang M, Zhong H, Mei F, Li Z, Sun L, Zhang T, Shi Y, Fan Z. Genetic Spectrum and Genotype-Phenotype Correlations in a Chinese Cohort With Nanophthalmos With Secondary Angle-Closure Glaucoma. Invest Ophthalmol Vis Sci. 2025 Jun 2;66(6):9. doi: 10.1167/iovs.66.6.9. PMID: 40459495; PMCID: PMC12136104.

5. Shi, Y., Liu, W., Hu, J., Qiu, W. Q., He, X., Gao, Y., Zhang, X., & Fan, Z*. (2025). The Role of Menopause and Its Association with the Apolipoprotein E4 Allele for Age at Diagnosis of Glaucoma in Women. Ophthalmology science, 5(4), 100726. https://doi.org/10.1016/j.xops.2025.100726

6. Yu XW#, Zhang M, Zhao HX, Gao Y, Deng L, Shi Y, Fan ZG*. Nanophthalmos-Associated MYRF gene mutation facilitates intraocular inflammation in mice. Int Immunopharmacol. 2024 Aug 20;137:112519. doi: 10.1016/j.intimp.2024.112519. Epub 2024 Jun 19. PMID: 38901241.

7. Shi Y, Hu J, Liu W, Qiu WQ, He X, Zhang M, Gao Y, Zhang X, Fan Z. Female-Specific Association between the Apolipoprotein E E4 Allele and Age at Diagnosis of Glaucoma in UK Biobank. Ophthalmol Glaucoma. 2025 Jan-Feb;8(1):53-62. doi: 10.1016/j.ogla.2024.07.009. Epub 2024 Aug 7. PMID: 39097094.

8. Pei XT#, Wang SH, Qing GP, Yu XW, Shi Y, Yang WL, Wang NL, Fan ZG*. Zonular instability-associated morphologic features in eyes with primary angle closure disease using the swept-source anterior segment - optical coherence tomography system. BMC Ophthalmol. 2024 Apr 30;24(1):203. doi: 10.1186/s12886-024-03462-1. PMID: 38684941.

9. Tang YZ#, Gao Y#, Yu XW, Zhong HY, Gong GC, Mei F, Fan ZG*, Shi Y. Novel diagnostic indicators for acute angle closure secondary to lens subluxation based on anterior segment and lens parameters. Heliyon. 2024 Jan 26;10(3):e25164. doi: 10.1016/j.heliyon.2024.e25164. PMID: 38327450.

10. 石砚,钟红钰,余晓伟,范志刚*.恶性青光眼的诊疗进展及新认识[J].眼科, 2024(3).

11. 张天睿,余晓伟,石砚,范志刚*.真性小眼球性葡萄膜渗漏综合征的病理生理学机制与治疗进展[J].微创医学,2023,18(02):137-142.

12. 孙珑彦,石砚,范志刚*.他氟前列素滴眼液治疗青光眼的应用研究进展[J].国际眼科纵览,2023,47(03):193-202.

13. Tang Yizhen#, Shi Yan, Zhigang Fan*. The mechanism and therapeutic strategies for neovascular glaucoma secondary to diabetic retinopathy. Front Endocrinol (Lausanne). 2023 Jan 23;14:1102361. doi: 10.3389/fendo.2023.1102361.

14. Zhang Dandan#, Sun Nannan#, Guo Congcong, Lee Junhui, Zhang Jiamin, Zhao Zhenni, Yu Xiaowei, Han Yin, Ge Jian*, Zhigang Fan*. Psychological stress induces moderate pathology in the ganglion cell layer in mice. Molecular Vision. 2022 Dec 21;28:451-459.

15. Xiaowei Yu#, Brad Kline, Ying Han, Yan Gao, Zhigang Fan*, Yan Shi*. Weill-Marchesani syndrome 4 caused by compound heterozygosity of a maternal submicroscopic deletion and a paternal nonsense variant in the ADAMTS17 gene: A case report[J]. American Journal of Ophthalmology Case Reports, 2022 Apr 14;26:101541.

16. 高妍,辛晨,石砚,余晓伟,范志刚*.改良式小梁切除联合深层巩膜切除术[J].眼科,2022,31(03):175-180.DOI:10.13281/j.cnki.issn.1004-4469.2022.03.003.

17. 余晓伟,石砚,高妍, 范志刚*. TMEM98 基因突变致真性小眼球1 家系[J]. 中华眼科杂志, 2022, 58(11): 932-935.

18. 葛坚, 石砚, 范志刚*. Ahmed青光眼引流阀植入术的应用及进展[J]. 中华眼科杂志, 2022, 58(1):8.

19. Xiaowei Yu#, Nannan Sun#, Congcong Guo, Zhenni Zhao, Meifang Ye, Jiamin Zhang, Jian Ge*, Zhigang Fan*, Evaluation of MYRF as a candidate gene for primary angle closure glaucoma. Molecular Vision, 2021, Dec 29;27:734-740.

20. Xue Yang, Xiaowei Yu, Zhenni Zhao, Yuqing He, Jiamin Zhang, Xiaoqian Su, Nannan Sun*, Zhigang Fan*, Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure, Journal of Zhejiang University Science, 2021, 22(9):746-756.

21. Xiaowei Yu#, Zhenni Zhao#, Dandan Zhang, Xue Yang, Nannan Sun, Yixiu Lin, Jiamin Zhang, Zhigang Fan*, Anterior vitrectomy, phacoemulsification cataract extraction and irido-zonulo-hyaloid-vitrectomy in protracted acute angle closure crisis, Int Ophthalmol, 2021 Sep;41(9):3087-3097.

22. Xiaowei Yu#, Nannan Sun#, Xue Yang#, Zhenni Zhao, Jiamin Zhang, Miao Zhang, Dandan Zhang, Jian Ge*, Zhigang Fan*, Myelin regulatory factor deficiency is associated with the retinal photoreceptor defects in mice, Vis Neurosci, 2021, 5(38):E005

23. Xiaowei Yu#, Nannan Sun#, Xue Yang, Zhenni Zhao, Xiaoqian Su, Jiamin Zhang, Yuqing He, Yixiu Lin, Jian Ge*, Zhigang Fan*, Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice, Invest. Ophthalmol. Vis. Sci, 2021, Mar;62(3):1

24. Xue Yang, Nannan Sun, Zhenni Zhao, Shuxiang He , Miao Zhang, Dandan Zhang, Xiaowei Yu, Jiamin Zhang, Zhigang Fan*, Coinheritance of OLFM2 and SIX6 variants in a Chinese family with juvenile-onset primary open-angle glaucoma: A case report, World J Clin Cases, 2021, 9(3): 697-706

25. 杨雪#，余晓伟，范志刚*，原发性开角型青光眼的免疫机制，眼科，2021（1）：5-10