张凯教授团队内包括1名博导和2名硕导，共培养研究生16名，在读学生包括3名博士和4名硕士研究生，2021年共发表SCI论文14篇，单篇最高影响因子12.291分。在张凯教授带领下，该团队学术氛围浓厚，学习氛围紧凑而不紧张，严谨而不苛刻，除了日常的临床工作、科研训练外，每月一次的科研组会，每周一次的文献学习会，每日轮值的清晨病例汇报等为学生们提供了良好的学习平台。

近五年课题：

(1) 科技部, 国家重点研发计划项目, 2021YFC2401201, 支撑迷走神经刺激器临床应用的青少年/成人癫痫诊疗规范研究, 2021-12 至今, 400万元, 在研, 课题负责人

(2) 首都卫生发展科研专项项目, 重点攻关, 2022-1-1071, 局灶性皮质发育不良的智能化诊断和微创化外科治疗的临床体系建立, 2022-01 至今, 99.96万元, 在研, 主持

(3) 国家自然科学基金委员会, 面上项目, 82071457, 局灶性皮质发育不良Ⅲa智能化影像诊断及其颞叶新皮质致痫性研究, 2021-01-01 至 2024-12-31, 55万元, 在研, 主持

(4) 国家自然科学基金委员会, 青年科学基金项目, 81701276, 基于颅内脑电的人类前岛叶皮层神经网络与认知功能电生理机制研究, 2018-01-01 至 2020-12-31, 20万元, 结题, 参与

(5) 国家自然科学基金委员会, 面上项目, 81771399, 基于颅内脑电的人类情绪记忆增强效应的神经电生理机制研究, 2018-01-01 至 2021-12-31, 54万元, 结题, 主持

(6) 国家自然科学基金委员会, 应急管理项目, 81641053, 基于癫痫患者立体脑电信号的人类顶内沟皮层功能定位与相关脑网络的研究, 2017-01-01 至 2017-12-31, 10万元, 结题, 主持

近五年课题：

(1) 科技部, 国家重点研发计划项目, 2021YFC2401201, 支撑迷走神经刺激器临床应用的青少年/成人癫痫诊疗规范研究, 2021-12 至今, 400万元, 在研, 课题负责人

(2) 首都卫生发展科研专项项目, 重点攻关, 2022-1-1071, 局灶性皮质发育不良的智能化诊断和微创化外科治疗的临床体系建立, 2022-01 至今, 99.96万元, 在研, 主持

(3) 国家自然科学基金委员会, 面上项目, 82071457, 局灶性皮质发育不良Ⅲa智能化影像诊断及其颞叶新皮质致痫性研究, 2021-01-01 至 2024-12-31, 55万元, 在研, 主持

(4) 国家自然科学基金委员会, 青年科学基金项目, 81701276, 基于颅内脑电的人类前岛叶皮层神经网络与认知功能电生理机制研究, 2018-01-01 至 2020-12-31, 20万元, 结题, 参与

(5) 国家自然科学基金委员会, 面上项目, 81771399, 基于颅内脑电的人类情绪记忆增强效应的神经电生理机制研究, 2018-01-01 至 2021-12-31, 54万元, 结题, 主持

(6) 国家自然科学基金委员会, 应急管理项目, 81641053, 基于癫痫患者立体脑电信号的人类顶内沟皮层功能定位与相关脑网络的研究, 2017-01-01 至 2017-12-31, 10万元, 结题, 主持

1: Neuroimaging gradient alterations and epileptogenic prediction infocal cortical dysplasia Ⅲa. Journal of Neural Engineering. 2022,-:-. Mo J,Zhang J, Hu W, Shao X, Sang L, Zheng Z, Zhang C, Wang Y, Wang X, Liu C, Zhao B,Zhang K* SCI(IF=5.484)

2: Atlas of lesion locations and postsurgical seizure freedom infocal cortical dysplasia: A MELD study. Epilepsia. 2022,63(1):61-74. KonradWagstyl (first author), Zhang Kai (middle author), Sophie Adler (correspondingauthor)) SCI(IF=5.866)

3:Clinical features of automatisms and correlation with the seizure onset zones:A cluster analysis of 74 surgically-treated cases. Seizure. 2021,94:82-89. YangB, Mo J, Zhang C, Wang X, Sang L, Zheng Z, Gao D, Zhao X, Wang Y, Liu C, ZhaoB, Guo Z, Shao X, Zhang J, Zhang K*, Hu W* SCI(IF=3.184)

4: Temporal Order of Signal Propagation Within and Across IntrinsicBrain Networks. Proceedings of the National Academy of Sciences of the UnitedStates of America. 2021,118(48):-. Veit MJ, Kucyi A, Hu W, Zhang C, Zhao B, GuoZ, Yang B, Sava-Segal C, Perry C, Zhang J, Zhang K*, Parvizi J* SCI(IF=11.205)

5: The amplitude of low-frequency fluctuation predicts levodopatreatment response in patients with Parkinson’s disease. Parkinsonism andrelated disorders. 2021,-:-. Yang B#, Wang X#, Mo J#, Li Z, Gao D, Bai Y, ZouL, Zhang X, Zhao X, Wang Y, Liu C, Zhao B, Guo Z, Zhang C, Hu W, Zhang J*,Zhang K* SCI(IF=4.891)

6: The electroclinical features and surgical outcomes of inferiorperisylvian epilepsy. Epilepsy and Behavior. 2021,-:-. Liu HG#, Yang BW#, ZhaoBT, Zheng Z, Gao DM, Shao XQ, Zhang K, Zhang JG, Hu WH SCI(IF=2.937)

7: 立体脑电图引导射频热凝毁损治疗下丘脑错构瘤相关癫痫的长期疗效观察. 中华神经外科杂志. 2021,37(08):771-775. 刘畅，张凯，郑重，周峰，解飞，李冬智，杨晓丽，高冬梅，马延山，桑林* 核心期刊

8: 低高频丘脑前核电刺激治疗药物难治性癫痫疗效分析（附９例临床分析）. 立体定向和功能性神经外科杂志. 2021,34(02):71-73+89.李敬军，王垚，杨博文，张弨，郑重，胡文瀚，邵晓秋，张建国，张凯* 核心期刊

9: 静息态功能磁共振在局灶性皮质发育不良癫痫患者中定位致痫区的价值. 立体定向和功能性神经外科杂志. 2021,34(03):129-134.杨博文，赵宝田，莫嘉杰，桑林，胡文瀚，张弨，王秀，张建国*，张凯* 核心期刊

10: 磁共振引导激光间质热疗治疗药物难治性癫痫的手术策略及疗效. 中华神经外科杂志. 2021,37(08):764-770. 胡文瀚，莫嘉杰，刘畅，王秀，刘焕光，赵宝田，邱佳冀，高冬梅，邵晓秋，张建国*，张凯* 核心期刊

11:Stereoelectroencephalography-guided radiofrequency thermocoagulation forhypothalamic hamartoma:Electroclinicalpatterns and the relationship with surgical prognosis. Epilepsy and Behavior.2021,-:-. Liu C, Zheng Z, Shao XQ, Li CD, Yang XL, Zhang C, Sang L, Xie F, ZhouF, Hu WH, Zhang K* SCI(IF=2.937)

12: Automatic analysis of integrated magnetic resonance and positronemission tomography images improves the accuracy of detection of focal corticaldysplasia type IIb lesions. European journal of neuroscience. 2021,53(9):3231-3241. Lin Y, Mo J, Jin H, Cao X, ZhaoY, Wu C, Zhang K*, Hu W*, Lin Z* SCI(IF=3.386)

13: Intracranial electroencephalography reveals selective responsesto cognitive stimuli in the periventricular heterotopias. journal ofneuroscience. 2021,41(17):3870-3878. Akkol S, Kucyi A, Hu W, Zhao B, Zhang C,Sava- Segal C, Liu S, Razavi B, Zhang J, Zhang K*, Parvizi J* SCI(IF=5.673)

14:Neural Networks Underlying Hyperkinetic Seizures: A Quantitative PET and SEEG Study. Epilepsy and Behavior. 2021,-:-.Wang X, Hu WH, Zhang C, Shao XQ, Sang L, Zheng Z, Wang Y, Zhao BT,Gao DM, Mo JJ, Zhang JG, ZhangK* SCI(IF=2.937)

15: Whole-brain morphological alterations associated with trigeminalneuralgia. Journal of headache and pain. 2021,22(1):-. Mo J, Zhang J, Hu W, LuoF*, Zhang K* SCI(IF=7.277)

16:Neuroimaging phenotyping and assessment ofstructural-metabolic-electrophysiological alterations in the temporal neocortexof focal cortical dysplasia Ⅲa. journal of magnetic resonance imaging.2021,54(3):925-935. Mo J#, Wei W#, Liu Z#, Zhang J, Ma Y, Sang L, Hu W, ZhangC, Wang Y, Wang X, Liu C, Zhao B, Gao D, Tian J*, Zhang K*, SCI(IF=4.813)

17:Deep Brain Stimulation in Treatment-Resistant Depression: A Systematic Reviewand Meta-Analysis on Efficacy and Safety. Frontiers in neuroscience. 2021,15:-.Youliang Wu#, Jiajie Mo #, Lisen Sui, Jianguo Zhang, Wenhan Hu, Chao Zhang, YaoWang, Chang Liu, Baotian Zhao, Xiu Wang, Kai Zhang*, Xuemin Xie* SCI(IF=4.677)

18:Quantitative assessment of structural and functional changes in temporal lobeepilepsy with hippocampal sclerosis. Quantitative Imaging in Medicine andSurgery. 2021,11-5:1782-1795. Jiajie Mo#, Baotian Zhao#, Sophie Adler, JianguoZhang, Xiaoqiu Shao, Yanshan Ma, Lin Sang, Wenhan Hu, Chao Zhang, Yao Wang, XiuWang, Chang Liu, Kai Zhang* SCI(IF=3.226)

19: Hemispherectomy Outcome Prediction Scale: Development andvalidation of a seizure freedom prediction tool. Epilepsia. 2020,-:-. AlexanderG. Weil(first author), Zhang K(mid author), Fallah A* et al. SCI(IF=6.040)

20:The Rolandic operculum generates different semiologies in insulo-opercular andtemporal lobe epilepsies. Epilepsy and Behavior. 2020,114:-. Wang Y, Wang X,Zhao BT, Sang L, Zhang C, Hu WH, Shao XQ, Zhang JG*, Zhang K* SCI(IF=2.937)

21: Deep Learning Model for the Automated Detection andHistopathological Prediction of Meningioma. Neuroinformatics. 2020,-:-. ZhangH#, Mo J#, Jiang H, Li Z, Hu W, Zhang C, Wang Y, Wang X, Liu C, Zhao B, ZhangJ*, Zhang K* SCI(IF=3.300)

22: Aberrant Metabolic Patterns Networks in Insular Epilepsy. Frontiers in Neurology. 2020,11 :605256. Zhao B,Seguin C, Ai L, Sun T, Hu W, Zhang C, Wang X, Liu C, Wang Y, Mo J, Zalesky A, Zhang K*, Zhang J* SCI(IF=2.889)

23: Automatic analysis of integrated magnetic resonance and positronemission tomography images improves the accuracy of detection of focal corticaldysplasia type IIb lesions. European Journal of neuroscience. 2020,-:-. Lin Y, Mo J, Jin H, Cao X, Zhao Y, Wu C*,Zhang K*, Hu W*, Lin Z SCI(IF=3.115)

24:Effective connectivity among the hippocampus, amygdala, and temporal neocortexin epilepsy patients: A cortico-cortical evoked potential study.. Epilepsy andBehavior. 2020,115:107661. Guo Z#, Zhao B#, Hu W, Zhang C, Wang X, Wang Y, LiuC, Mo J, Sang L, Ma Y, Shao X, Zhang J*, Zhang K* SCI(IF=2.508)

25: Semiologic subgroups of insulo-opercular seizures based onconnectional architecture atlas. Epilepsia. 2020,61-5:984-994. Wang H,McGonigal A, Zhang K, Guo Q, Zhang B, Wang X, Wang X, Lin J, Song X, Feng Q,Wang S, Wang M, Shao X, Liu X, Wang L, Zhou W* SCI(IF=6.040)

26: Network of ictal head version in mesial temporal lobe epilepsy.Brain and Behavior. 2020,10-11:e01820. Wang Y, Wang X, Sang L, Zhang C, ZhaoBT, Mo JJ, Hu WH, Shao XQ, Wang F, Ai L, Zhang JG, Zhang K* SCI(IF=2.091)

27: 合并海马硬化的颞叶内侧型癫痫的网络分析. 立体定向和功能性神经外科杂志. 2020,33-02:5-8. 王垚、王秀、桑林、刘畅、郭志浩、张子卿、胡文瀚、张建国、张凯* 核心期刊

28:Intrinsic brain activity changes in temporal lobe epilepsy patients revealed byregional homogeneity analysis. Seizure. 2020,81:117-122. Zhao B#, Yang B#, TanZ, Hu W, Sang L, Zhang C, Wang X, Wang Y, Liu C, Mo J, Shao X, Zhang J*, ZhangK*. SCI(IF=2.522)

29: Electrophysiological dynamics of antagonistic brain networksreflect attentional fluctuations. Nature Communications. 2020,11-1:325. KucyiA#, Daitch A#, Raccah O#, Zhao B, Zhang C, Esterman M, Zeineh M, Halpern CH,Zhang K, Zhang J*, Parvizi J*. SCI(IF=12.121)

30:Epileptogenic network of focal epilepsies mapped with cortico-cortical evokedpotentials. Clinical Neurophysiology. 2020,131-11:2657-2666. Zhi-hao Guo#,Bao-tian Zhao#, Sheela Toprani#, Wen-hanHu, Chao Zhang, Xiu Wang, Lin Sang, Yan-shanMa, Xiao-qiu Shao, Babak Razavi, Josef Parvizi, Robert Fisher*, Jian-guo Zhang*, Kai Zhang* SCI(IF=3.214)

31:Resective epilepsy surgery in tuberous sclerosis complex: a nationwidemulticentre retrospective study from China. Brain. 2020,0:1-12. Shiyong Liu#,Tao Yu#, Yuguang Guan#, Kai Zhang#, Ping Ding#, Lei Chen, Yongzhi Shan, QiangGuo, Qingzhu Liu, Yi Yao, Meihua Yang, Shaohui Zhang, Yuanxiang Lin, Rui Zhao,Zhiqi Mao, Juncheng Zhang, Chunqing Zhang, Rui Zhang, Zhiquan Yang, RuobingQian, Yunlin Li, Guangming Zhang, Liu Yuan, Weidon SCI(IF=11.814)

32:Seizure and cognitive outcomes of posterior quadrantic disconnection: a seriesof 12 pediatric patients. British Journal of Neurosurgery. 2019,-:1-6. YaoWang, Chao Zhang, Xiu Wang, Lin Sang, Feng Zhou, Jian-Guo Zhang, Wen-Han Hu,Kai Zhang* SCI(IF=1.481)

33: Superior Frontal SulcusFocal Cortical Dysplasia Type II: AnMRI, PET, and Quantified SEEG Study. frontiers in Neurology.2019,10:1253. Chao Zhang, Bao-tian Zhao, Aileen McGonigal, Wen-han Hu, XiuWang, Xiao-qiu Shao, Yan-shan Ma, Jian-guo Zhang, Kai Zhang* SCI(IF=2.635)

34: Motor cortex stimulation: a systematic literature-based analysisof effectiveness and case series experience. BMC Neurology. 2019,19(48):1-9.Jia-Jie Mo, Wen-Han Hu, Chao Zhang, Xiu Wang, Chang Liu, Bao-Tian Zhao,Jun-Jian Zhou, Kai Zhang* SCI(IF=2.233)

35: Automated detection of hippocampal sclerosis using clinicallyempirical and radiomics features. Epilepsia. 2019,60:2519-2529. Jiajie Mo,Zhenyu Liu, Kai Sun, Yanshan Ma, Wenhan Hu, Chao Zhang, Yao Wang, Xiu Wang,Chang Liu, Baotian Zhao, Kai Zhang*, Jianguo Zhang*, Jie Tian* SCI(IF=5.562)

36:Electroclinical features of insulo-opercular epilepsy: an SEEG and PET study.Annals of Clinical and Translational Neurology. 2019,6(7):1165-1177. Xiu Wang,Wenhan Hu, Aileen McGonigal, Chao Zhang, Lin Sang, Baotian Zhao, Tao Sun, FengWang, Jian-guo Zhang, Xiaoqiu Shao*, Kai Zhang* SCI(IF=4.656)

37:Symptomatogenic zone and network of oroalimentary automatisms in mesialtemporal lobe epilepsy.. Epilepsia. 2019,60(6):1150-1159. Yao Wang, Xiu Wang,Jia‐jie Mo, Lin Sang, Bao‐tian Zhao, Chao Zhang, Wen‐han Hu, Jian‐guo Zhang, Xiao‐qiu Shao, Kai Zhang*SCI(IF=5.562)

38: Focal cortical dysplasia II-related seizures originate from thebottom of the dysplastic sulcus: A stereoelectroencephalography study..Clinical Neurophysiology. 2019,130(9):1596-1603. Wen-han Hu, Bao-tian Zhao,Chao Zhang, Xiu Wang, Lin Sang, Xiao-qiu Shao, Hui Qiao, Jian-guo Zhang, KaiZhang* SCI(IF=3.675)

39: Clinical Value of Machine Learning in the Automated Detection ofFocal Cortical Dysplasia Using Quantitative Multimodal Surface-Based Features..Frontiers in Neuroscience . 2019,12:1008. Mo Jia-Jie, Zhang Jian-Guo, LiWen-Ling, Chen Chao, Zhou Na-Jing, Hu Wen-Han, Zhang Chao, Wang Yao, Wang Xiu,Liu Chang, Zhao Bao-Tian, Zhou Jun-Jian, Zhang Kai* SCI(IF=3.877)

40: Value of stereo-electroencephalogram in reoperation of patientswith pharmacoresistant epilepsy: a single center, retrospective study. Britishjournal of neurosurgery. 2018,32(6):663-670. Mo jiajie, Hu Wenhan, Zhang Chao,Wang Xiu, Liu Chang, Zhao Baotian, Zhou Junjian, Zhang Kai SCI(IF=1.238)

41: PET-MRI影像融合技术在药物难治性癫痫术前评估中的价值. 中华神经外科杂志. 2017,33（6）:559-563. 桑林，张凯*，张建国，马延山，邵晓秋，张弨，赵宝田，胡文瀚，郑重，周峰核心期刊