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王蕾，首都医科大学教授，博导，1996年博士毕业于北京中医药大学，毕业后一直在首都医科大学中医药学院从事中医方剂学教学、科研和临床工作。曾先后评为“北京市高等学校优秀青年骨干教师”，"北京市长城学者"，入选“国家中医药管理局第四批全国中医临床优秀人才”，曾获得校级优秀干部、优秀共产党员等荣誉。科研方面，在补肾中药促进神经再生修复研究方面取得一定成果，先后主持国家自然科学基金4项，北京市自然科学基金3项；在国内外学术期刊上发表研究论文120余篇；主编和副主编著作8部；国家发明授权专利2项，获中华中医药学会学术著作奖三等奖和科技进步奖三等奖个1项。
国家自然科学基金，补肾益髓方调控外泌体miR-124/CEBPα和miR-155/CEBPβ介导小胶质细胞M1/M2极化促进髓鞘再生的机制研究（81873252），主持，60万元，2019.1-2022.12
论文：
1.Pei-Yuan Zhao, Jing Ji, Xi-Hong Liu, Hui Zhao, Bin Xue, Liang-Yun Jin, Yong-Ping Fan, Wen-Jing Zhao, Lei Wang*. Bu-Shen-Yi-Sui capsule, an herbal medicine formula, promotes remyelination by modulating the molecular signals via exosomes in mice with experimental autoimmune encephalomyelitis.Oxidative Medicine and Cellular Longevity, 2020, doi: 10.1155/2020/7895293.
2.Yaqin Sun, Jing Ji, Zheng Zha, Hui Zhao, Bing Xue, Liangyun Jin,Lei Wang*. Effect and mechanism of Catalpol on remyelination via regulation of the NOTCH1 signaling pathway, Frontiers in Pharmacology, 2021,doi: 10.3389/fphar.2021.628209.
3.Zheng Zha,Yan-Fang Gao, Jing Ji, Ya-Qin Sun, Jun-Ling Li, Fang Qi, Nan Zhang,Liang-Yun Jin, Bing Xue, Tao Yang, Yong-Ping Fan, Hui Zhao, Lei Wang*.Bu Shen Yi Sui capsule alleviates neuroinflammation and demyelination by promoting microglia toward M2 polarization,which correlates with changes in miR-124 and miR-155 in experimental autoimmune encephalomyelitis. Oxidative Medicine and Cellular Longevity,2021, doi.10.1155/2021/5521503.
4.Haolong Liu#, Yiyi Zhao#, Qi Zheng, Tao Yang, Hui Zhao,Haiyan Zou, Yongping Fan,* Hongzhu Guo,* Lei Wang*. Identification and Quantification of Bu Shen Yi Sui Capsule by UPLC-LTQ-Orbitrap-MS and UPLC-QTOF-MS/MS. Journal of Chromatographic Science, 2022, 60(5):450–457.
5.Jing Ji, Ya-Qin Sun, Zheng Zha, Bing Xue, Jun-Ling Li, Liang-Yun Jin, Fang Qi, Nan Zhang, Hui Zhao, Yong-Ping Fan, Lei Wang*.Bu Shen Yi Sui Capsules Promote Remyelination by Regulating MicroRNA-219 and MicroRNA-338 in Exosomes to Promote Oligodendrocyte Precursor Cell Differentiation.Evidence-Based Complementary and Alternative Medicine, 2022, doi: 10.1155/2022/3341481.
6.Zheng Zha, Yi-Jiang Liu, Si-Si Liu, Nan Zhang, Jun-Ling Li, Fang Qi, Liang-Yun Jin, Bing Xue,2 Tao Yang, Yong-Ping Fan, Hui Zhao, Lei Wang#. Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification.Mediators of Inflammation,2022, doi: 10.1155/2022/9241261.
著作
《中医脑病方药运用》 主编 中国中医药出版社 202001
补肾法为主促进多发性硬化免疫稳态重建和神经功能康复的作用研究 中华中医药学会科学技术奖三等奖
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