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肖荣 博士/教授（二级），首都医科大学营养与食品卫生学科带头人，主要从事营养与食品卫生学教育教学和人才培养、科学研究及其他学科建设工作。主要研究方向是营养与神经科学及营养干预。长期从事膳食成分与营养相关代谢性疾病关联性及分子机制研究，尤其是胆固醇氧化代谢产物对认知功能障碍相关疾病发生与发展作用及表观遗传学调控机制、生物标志物、预测模型及营养干预研究。主持国家级课题（含国家自然科学基金的重点和面上项目及国家“863”子课题项目）以及北京市自然基金项目等20余项科研项目，作为通讯作者/第一作者发表学术论文150余篇，其中SCI收录论文80余篇，主编、副主编或参编国家级规划教材或专著30部。兼任中国营养学会副理事长及营养与神经科学分会和北京神经内科学会基础与转化医学专业委员会副主任委员、北京预防医学会常务理事等；兼任生理科学进展、中国食品卫生杂志等杂志的编委等。先后获北京市属高等学校人才强教深化计划“创新人才”、首都医科大学“优秀导师”、“优秀共产党员”等称号及中国营养学会“百名英才”称号。
部分国家级课题（作为主持人）
1. 27-羟基胆固醇通过肠道菌群代谢参与阿尔茨海默病发生中miR-107/m6A/突触功能因子的调控作用及机制（82173501）
国家自然科学基金资助项目 2022-2025年
2. 维生素D联合叶酸和维生素B12通过调节27-羟基胆固醇代谢关键因子改善轻度认知障碍发生的作用及机制 （81973021）
国家自然科学基金资助项目 2020-2023年
3. 膳食氧化固醇通过调节肠道微生态诱导的阿尔茨海默发生发展的作用及机制 （81673149）
国家自然科学基金资助项目 2017-2020年
4. 膳食胆固醇及其氧化代谢产物在阿尔茨海默病发病过程中的作用及其相关机制研究 （81330065）
国家自然科学基金资助重点项目 2014-2018年
5.大豆异黄酮预防及修复脑血管内皮损伤的作用及其机制（81172661）国家自然科学基金资助项目 2012-2015年
6. 大豆异黄酮拮抗Aβ诱导的星形胶质细胞分子炎症信号的调控作用 （30972470）国家自然科学基金资助项目 2010-2012年
7.改善心脑血管功能和骨质疏松的功能食品升级项目子课题-植物化学物对神经系统的保护作用及其分子机制-功能验证研究（2010AA023003）国家高技术研究发展计划（863计划）2010-2012年
部分发表的科研论文（通讯作者）
1. Wang T#, Zhang X#, Wang Y, LiuW, Wang L, Hao L, Ju M, Xiao R. High cholesterol and 27-hydroxycholesterolcontribute to phosphorylation of tau protein by impairing autophagy causinglearning and memory impairment in C57BL/6J mice. J Nutr Biochem. 2022 18:109016.
2. Tao Wang, Shanshan Cui, LingHao, Wen Liu, Lijing Wang, Mengwei Ju, Wenjing Feng, Rong Xiao. Regulation ofTh17/Treg balance by 27-hydroxycholesterol and 24S-hydroxycholesterolcorrelates with learning and memory ability in mice. International Journal of MolecularSciences. 2022, 23(8):4370.
3.Wen Liu, Cui Zhou, YushanWang,Huiyan Yu, Xiaona Zhang, Tao Wang, Lijing Wang, Ling Hao, Zhongsheng Qin,Rong Xiao*, Vitamin D deficiency is associated with disrupted cholesterolhomeostasis in patients with mild cognitive impairment, The Journal of Nutrition. 2021,151:3865–3873.
4.Lijing Wang, Kuo Liu, Xiaona Zhang, Yushan Wang, Wen Liu,Tao Wang, Ling Hao, Mengwei Ju, RongXiao* , the effect and mechanism of cholesterol and vitamin B12 on multi-domaincognitive function: a prospective study on Chinese middle-aged and older adults,Frontiersin aging neuroscience. 2021, 13:707958.
5.Xiaona Zhang, Yushan Wang, WenLiu, Tao Wang, Lijing Wang, Ling Hao, Mengwei Ju, Rong Xiao*, Diet quality, gutmicrobiota and microRNAs associated with mild cognitive impairment inmiddle-aged and elderly Chinese population, American Journal of ClinicalNutrition. 2021, 114(2):429-440.
6. Ying Wang1, Yu An1, Weiwei Ma,Huiyan Yu, Yanhui Lu, Xiaona Zhang, Yushan Wang, Wen Liu, Tao Wang, Rong Xiao*,27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenicmice through microbiota dysbiosis and intestinal barrier dysfunction, Journalof Neuroinflammation, 2020, 17:199
7.Yushan Wang, Xiaona Zhang, TaoWang,Wen Liu, Lijing Wang, Ling Hao, Mengwei Ju, Rong Xiao*,27-Hydroxycholesterol promotes the transfer of astrocyte-derived cholesterol toneurons in co-cultured SH-SY5Y cells and C6 cells, Frontiers in Cell andDevelopmental Biology, 2020, 8:580599.
8. Yu An, Xiaona Zhang, Ying Wang,Yushan Wang, Wen Liu, Tao Wang, Zhongsheng Qin Rong Xiao*, Longitudinal andNonlinear Relations of Dietary and Serum cholesterol in Midlife with CognitiveDecline: Results from EMCOA Study, Molecular Neurodegeneration, 2019, 14(1): 51
9. Yu An, Lingli Feng, XiaonaZhang, Ying Wang, Yushan Wang, Lingwei Tao, Zhongsheng Qin, Rong Xiao*, DietaryIntakes and Biomarker Patterns of Folate, Vitamin B6 and Vitamin B12 Can beAssociated with Cognitive Impairment by Hypermethylation of Redox Related GenesNUDT15 and TXNRD1, Clinical Epigenetics, 2019, 11(1):139
10.Xiaona Zhang 1, Yuandi Xi 1,Huiyan Yu, Yu An, Ying Wang, Lingwei Tao, Yushan Wang, Wen Liu, Tao Wang, RongXiao* 27-hydroxycholesterol promotes Aβ accumulation via altering Aβ metabolismin mild cognitive impairment patients and APP/PS1 mice. Brain Pathology. 2019,29(4):558-573
11.Lingwei Tao, Kuo Liu, Si Chen,Huiyan Yu, Yu An, Ying Wang, Xiaona Zhang, Yushan Wang, Zhongsheng Qin, RongXiao*. Dietary Intake of Riboflavin and Unsaturated Fatty Acid can Improve theMulti-domain Cognitive Function in Middle-aged and Elderly Populations: A2-year Prospective Cohort Study. Frontiers in Aging Neuroscience.2019,11,226.
12.Si Chen†, Cui Zhou†, Huiyan Yu,Lingwei Tao, Yu An, Xiaona Zhang, Ying Wang, Yushan Wang, Rong Xiao*,27-hydroxycholesterol contributes to lysosomal membranepermeabilization-mediated pyroptosis in co-cultured SH-SY5Y cells and C6 cells.FrontiersIn Molecular Neuroscience. 2019, 12:14
13.Yu An†, Lingli Feng†, XiaonaZhang, Ying Wang, Yushan Wang, Lingwei Tao, Yanhui Lu, Zhongsheng Qin and RongXiao*. Patterns of cognitive function in middle-aged and elderly Chineseadults—findings from the EMCOA study. Alzheimer's Research & Therapy.2018, 10:93.
14.Xiaona Zhang†, Chenyan Lv†, YuAn, Quanri Liu, Hongguo Rong, Lingwei Tao, Ying Wang, Yushan Wang, Rong Xiao*.Increased levels of 27-hydroxycholesterol induced by dietary cholesterol inbrain contribute to the learning and memory impairment in rats. Mol.Nutr. Food Res. 2018, 62(3): 1700531.
15.Hongguo Rong†, Yuandi Xi†, YuAn, Lingwei Tao, Xiaona Zhang, Huiyan Yu, Ying Wang, Zhongsheng Qin*, RongXiao*, The Correlation between Early Stages of Life Exposed to Chinese Famineand Cognitive Decline in Adulthood: Nutrition of Adulthood Plays an ImportantRole in the Link? Frontiers in aging neuroscience. 2018, 9:444.
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