现有国家级课题1个，国家自然科学基金面上项目，基于前瞻队列的颅内动脉瘤不稳定危险因素的人工智能分析和机理研究，82072036，课题经费64.44万元。

省部级课题2个，国家卫生健康委能力建设和继续教育中心，基于人工智能技术预测颅内未破裂动脉瘤不稳定模型的开发和验证：前瞻性，多中心登记研究，GWJJ2021100103，课题经费55万元；北京市卫生健康委员会，新型血管内支架治疗颅内动脉瘤的实验研究，11000022T000000424117-4，课题经费41万元。

一、重要学术论文: 近10年发表通讯作者SCI及其中文核心文章文章近80篇，其中包括国际顶刊杂志《Stroke》、《Neurology》和《Journal of Neurosurgery》。制订《颅内动脉夹层的影像学诊断中国专家共识》和《颅内夹层动脉瘤的血管内治疗中国专家共识》2项行业共识。组织推动全国最大的10家临床诊疗中心联合制订了《血流导向装置治疗颅内动脉瘤的中国专家共识》和《血流导向装置治疗颅内动脉瘤的中国专家指南》。文章如下

1. Wang K, Zhao S, Xie Z, Zhang M, Zhao H, Cheng X, Zhang Y, Niu Y, Liu J, Zhang TJ, Zhang Y, Wu Z, Chu J, Yang X, Wu N. Exome-wide Analysis of De Novo and Rare Genetic Variants in Patients With Brain Arteriovenous Malformation. Neurology. 2022 Apr 19;98(16):e1670-e1678.

2.Wang K, Zhang M, Zhao S, Xie Z, Zhang Y, Liu J, Zhang Y, Yang X, Wu N. Mutational spectrum of syndromic genes in sporadic brain arteriovenous malformation. Chin Neurosurg J. 2022 Feb 24;8(1):4.

3. Jian Liu#,Ying Zhang#, Wenqiang Li, Kun Wang, Yisen Zhang, Xinjian Yang*.Treatment oftrue posterior communicating artery aneurysms: Endovascular experience in asingle center. Interventional Neuroradiology. 2020,26(1):55-60.SCI

4. WenqiangLi, Shengzhang Wa, Zhongbin Tian, Wei Zhu, Yisen Zhang, Ying Zhang, Yang Wang,Kun Wang, Xinjian Yang, Jian Liu*.Discrimination of intracranial aneurysmrupture status: patient-specific inflow boundary may not be a must-havecondition in hemodynamic simulations. Neuroradiology. 2020,62(11):1485-1495.SCI

5. Turhon M, Kang H, Li M, Liu J, Zhang Y,Zhang Y, Huang J, Luo B, Liu J, Zhang H, Li T, Song D, Zhao Y, Guan S,Aximujiang A, Maimaitili A, Wang Y, Feng W, Wang Y, Wan J, Mao G, Shi H, ZhangX, Gu Y, Yang X. Treatment of fusiform aneurysms with a pipeline embolizationdevice: a multicenter cohort study. J Neurointerv Surg. 2022 Mar30:neurintsurg-2021-018539. 

6. Kang H, Luo B, Liu J, Zhang H, Li T, Song D,Zhao Y, Guan S, Maimaitili A, Wang Y, Feng W, Wang Y, Wan J, Mao G, Shi H, WangK, Yang X. Mortality after treatment of intracranial aneurysms with thePipeline Embolization Device. J Neurointerv Surg. 2022Jan;14(1):neurintsurg-2020-017002.

7. Turhon M, Kang H, Huang J, Li M, Liu J, ZhangY, Wang K, Yang X, Zhang Y. Atorvastatin for unruptured intracranialvertebrobasilar dissecting aneurysm (ATREAT-VBD): protocol for a randomised,double-blind, blank-controlled trial. BMJ Open. 2022 Apr 28;12(4):e059616.

8. Kang H, Luo B, Liu J, Zhang H, Li T, Song D,Zhao Y, Guan S, Maimaitili A, Wang Y, Feng W, Wang Y, Wan J, Mao G, Shi H,Zhang Y, Yang X. Postoperative occlusion degree after flow-diverter placementwith adjunctive coiling: analysis of complications. J Neurointerv Surg. 2022Apr;14(4):371-375.

9. Li W, Zhu W, Liu J, Yang X. Imbalanced flowchanges of distal arteries: An important factor in process of delayedipsilateral parenchymal hemorrhage after flow diversion in patients withcerebral aneurysms. Interv Neuroradiol. 2021 Dec;27(6):788-797.

10. Li W, Zhu W, Sun X, Liu J, Wang Y, Wang K,Zhang Y, Yang X, Zhang Y. Retreatment With Flow Diverters and Coiling forRecurrent Aneurysms After Initial Endovascular Treatment: A PropensityScore-Matched Comparative Analysis. Front Neurol. 2021 Jun 3;12:625652.

11. Zhu W, Li W, Tian Z, Zhang M, Zhang Y, WangK, Zhang Y, Yang X, Liu J. Nomogram for Stability Stratification of SmallIntracranial Aneurysm Based on Clinical and Morphological Risk Factors. FrontNeurol. 2021 Jan 15;11:598740.

12. Sui B, Bai X, Gao P, Lin Y, Zhang Y, LiangJ, Yang X. High-resolution vessel wall magnetic resonance imaging for depictingimaging features of unruptured intracranial vertebrobasilar dissectinganeurysms. J Int Med Res. 2021 Feb;49(2):300060520977388.

13. Kang H, Luo B, Liu J, Wang A, Zhang H, LiT, Song D, Zhao Y, Guan S, Wang Y, Feng W, Wang Y, Shi H, Liu J, Yang X. Anovel score for evaluating cerebral aneurysms treated with flow diversion:4F-flow diversion predictive score. Ther Adv Neurol Disord. 2021 Aug19;14:17562864211039336.

14. Kang H, Zhou Y, Luo B, Lv N, Zhang H, Li T,Song D, Zhao Y, Guan S, Maimaitili A, Wang Y, Feng W, Wang Y, Wan J, Mao G, ShiH, Yang X, Liu J. Pipeline Embolization Device for Intracranial Aneurysms in aLarge Chinese Cohort: Complication Risk Factor Analysis. Neurotherapeutics.2021 Apr;18(2):1198-1206.

15. Li W, Zhu W, Wang A, Zhang G, Zhang Y, WangK, Zhang Y, Wang C, Zhang L, Zhao H, Wang P, Chen K, Liu J, Yang X. Effect ofAdjusted Antiplatelet Therapy on Preventing Ischemic Events After Stenting forIntracranial Aneurysms. Stroke. 2021 Dec;52(12):3815-3825.

16. YangyangZhou, Xinzhi Wu, Zhongbin Tian, Xinjian Yang, Shiqing Mu*.Pipeline embolizationdevice with adjunctive coils for the treatment of unruptured large or giantvertebrobasilar aneurysms: a single-center experience. Frontiers in Neurology.2020,11:1-11.SCI

17. YongfengHan, Jian Liu, Zhongbin Tian, Ming Lv, Xinjian Yang, Zhongxue Wu*, Bu-LangGao.Factors affecting recurrence and management of recurrent cerebral aneurysmsafter initial coiling. Interventional Neuroradiology. 2020,26(3):300-308.SCI

18. Zhongbin Tian, Mingqi Zhang, GaohuiLi, Rongbo Jin, Xiaochang Leng, Ying Zhang, Kun Wang, Yisen Zhang, XinjianYang, Jianping Xiang, Jian Liu*.Hemodynamic differences by increasing lowprofile visualized intraluminal support (LVIS) stent local compaction acrossintracranial aneurysm orifice. Interventional Neuroradiology.2020,26(5):557-565.SCI

19. YisenZhang#, Zhongbin Tian#, Chuzhong Li, Jian Liu, Ying Zhang, Xinjian Yang, YazhuoZhang*.A modified endovascular treatment protocol for iatrogenic internalcarotid artery injuries following endoscopic endonasal surgery. Journal ofNeurosurgery. 2020,132(2):343-350.SCI

20. XinghuanDing#, Sen Zhao#, Qianqian Zhang, Zihui Yan, Yang Wang, Yong Wu, Xiaoxin Li ,Jian Liu, Yuchen Niu, Yisen Zhang, Mingqi Zhang, Huizi Wang, Ying Zhang,Weisheng Chen, Xinzhuang Yang, Pengfei Liu, Jennifer E Posey, James R Lupski,Zhihong Wu, Xinjian Yang, Nan Wu, Kun Wang*.Exome sequencing reveals a novelvariant in NFX1causing intracranial aneurysm in a Chinese family. Journal ofNeuroInterventional Surgery. 2020,12(2):221-226.SCI

21. Zhongbin Tian, Zhongxiao Wang,Wenqiang Li, Wei Zhu, Jian Liu, Ying Zhang, Xinjian Yang, Yisen Zhang*.Dynamiccontrast-enhanced MRI analysis for prognosis of intracranial dissectinganeurysm with intramural haematoma after endovascular treatment: anobservational registry study. Stroke and Vascular Neurology.2020,6(1):133–138.SCI

22. Bin Luo,Huibin Kang, Hongqi Zhang, Tianxiao Li, Jianmin Liu, Donglei Song, Yuanli Zhao,Sheng Guan, Aisha Maimaitili, Yunyan Wang, Wenfeng Feng, Yang Wang, JieqingWan, Guohua Mao, Huaizhang Shi, Xinjian Yang*.Pipeline Embolization device forintracranial aneurysms in a large Chinese cohort: factors related to aneurysmocclusion. Therapeutic Advances in Neurological Disorders. 2020,13:1-11.SCI

23. LuqiongJia, Jiejun Wang, Longhui Zhang, Yunfeng Zhang, Wei You, Xinjian Yang*, MingLv*.Pediatric Patient With a Giant Vertebrobasilar Dissecting AneurysmSuccessfully Treated With Three Pipeline Embolization Devices. Frontiers inNeurology. 2020,11:1-4.SCI

24. ZhongbinTian, Jian Liu, Ying Zhang, Yisen Zhang, Xiaolong Zhang, Hongqi Zhang, MingYang, Xinjian Yang*, Kun Wang*.Risk Factors of Angiographic Recurrence AfterEndovascular Coil Embolization of Intracranial Saccular Aneurysms: ARetrospective Study Using a Multicenter Database. Frontiers in Neurology.2020,11:1026.SCI

25. ZhongbinTian, Jian Liu, Ying Zhang, Yisen Zhang, Xiaolong Zhang, Hongqi Zhang, MingYang, Xinjian Yang*, Kun Wang*.Risk Factors of Angiographic Recurrence AfterEndovascular Coil Embolization of Intracranial Saccular Aneurysms: ARetrospective Study Using a Multicenter Database. Frontiers in Neurology.2020,11:1026.SCI

26. WenqiangLi#, Yisen Zhang#, Zhongbin Tian, Wei Zhu, Jian Liu, Ying Zhang, Xinjian Yang*,Decai Tian*.Statin treatment for unruptured intracranial aneurysms study: astudy protocol for a double-blind, placebo controlled trial. Stroke andVascular Neurology. 2020,5(4):410-415.SCI

27. 杨新健*, 张鸿祺*, 刘建民*, 李天晓*.血流导向装置治疗颅内动脉瘤的中国专家共识. 中华神经外科杂志.2020,36(5):433-445.核心期刊

28. Wei Zhu,Wenqiang Li, Zhongbin Tian, Yisen Zhang, Kun Wang, Ying Zhang, Jian Liu*,Xinjian Yang*.Stability Assessment of Intracranial Aneurysms Using MachineLearning Based on Clinical and Morphological Features. Translational StrokeResearch. 2020,11(6):1287-1295.SCI

29. MingqiZhang, Xinghuan Ding, Qianqian Zhang, Jian Liu, Yisen Zhang, Ying Zhang,Zhongbin Tian, Wenqiang Li, Wei Zhu, Huibin Kang, Zhongxiao Wang, Xinzhi Wu,Chao Wang, Xinjian Yang, Kun Wang*.Exome sequencing of 112 trios identifiesrecessive genetic variants in brain arteriovenous malformations. Journal ofNeuroInterventional Surgery. 2020,published online ahead of print, 2020 Aug26:Epub ahead of print.SCI

30. YisenZhang, Zhongbin Tian, Wei Zhu, Jian Liu, Yang Wang, Kun Wang, Ying Zhang,Xinjian Yang*, Wenqiang Li*.Endovascular treatment of bilateral intracranialvertebral artery aneurysms: an algorithm based on a 10-year neurointerventionalexperience. Stroke and Vascular Neurology. 2020,5(3):291-301.SCI

31. ZhongxiaoWang, Zhongbin Tian, Wenqiang Li, Jiejun Wang, Wei Zhu, Mingqi Zhang, YingZhang, Jian Liu, Kun Wang, Yisen Zhang*, Xinjian Yang*.Variation of Mass EffectAfter Using a Flow Diverter With Adjunctive Coil Embolization for SymptomaticUnruptured Large and Giant Intracranial Aneurysms. Frontiers in Neurology.2019,10:1191.SCI

32. Xinzhi Wu#, Zhongbin Tian, JianLiu, Yisen Zhang, Wenqiang Li, Ying Zhang, Junfan Chen, Yangyang Zhou, XinjianYang*, Shiqing Mu*.Patency of Posterior Circulation Branches Covered by FlowDiverter Device: A Hemodynamic Study. Frontiers in neurology. 2019,10:658.SCI

33. JiejunWang#, Yisen Zhang#, Ming Lv*, Xinjian Yang*, Zhongbin Tian, Jian Liu, PengLiu, Zefeng Miao, Luqiong Jia, Junfan Chen, Xinghuan Ding, Ying Zhang, Wei Zhu,Wenqiang Li, Kun Wang, Zhongxiao Wang.Application of the Pipeline EmbolizationDevice for Giant Vertebrobasilar Dissecting Aneurysms in Pediatric Patients.Frontiers in neurology. 2019,10:179.SCI

34. WenqiangLi, Yang Wang, Yisen Zhang, Kun Wang, Ying Zhang, Zhongbin Tian, Xinjian Yang*,Jian Liu*.Efficacy of LVIS vs. Enterprise Stent for Endovascular Treatment ofMedium-Sized Intracranial Aneurysms: A Hemodynamic Comparison Study. Frontiersin neurology. 2019,10:522.SCI

35. XinghuanDing#, Sen Zhao#, Qianqian Zhang, Zihui Yan, Yang Wang, Yong Wu, Xiaoxin li,Jian liu, Yuchen niu, Yisen Zhang, Mingqi Zhang, huizi Wang, Ying Zhang,Weisheng chen, Xin-Zhuang Yang, Pengfei liu, Jennifer e Posey, James r lupski,Zhihong Wu, Xinjian Yang*, Nan Wu*, Kun Wang*.NFX1Exome sequencing reveals anovel variant in causing intracranial aneurysm in a Chinese family. Journal ofneurointerventional surgery. 2019,12(2):221-226.SCI

36. JunfanChen#, Yisen Zhang, Zhongbin Tian, Wenqiang Li, Qianqian Zhang, Ying Zhang,Jian Liu*,Xinjian Yang*.Relationship between haemodynamic changes and outcomesof intracranial aneurysms after implantation of the pipeline embolisationdevice: a single centre study. Interventional neuroradiology.2019,25(6):671-680.SCI

37. Wei Su,Yisen Zhang, Junfan Chen, Jian Liu, Gary Rajah, Xinjian Yang*.225 intracranialaneurysms treated with the Low-profile Visualized Intraluminal Support (LVIS)stent: a single-center retrospective study.. Neurological Research.2018,40(6):445-451.SCI

38. Kun Wang#,Sen Zhao#, Qianqian Zhang, Xinghuan Ding, Jian Liu, Bo Long, Yisen Zhang,Xiangjun Tong, Shuyang Zhang, Jennifer E Posey, Bo Zhang, Zhihong Wu, Joshua DWythe, James R Lupski, Xinjian Yang* ,Nan Wu*.Perturbations of BMP/TGF-β andVEGF/VEGFR signalling pathways in non-syndromic sporadic brain arteriovenousmalformations (BAVM).. journal of medical genetics. 2018,55(10):675–684.SCI

39. Kun Wang,Sen Zhao, Qianqian Zhang, Xinghuan Ding, Michihiko Sugimoto, Bo Yuan, Jian Liu,Yisen Zhang, Yuchen Niu, Bo Long, Yiping Shen, Shuyang Zhang, Kuniya Abe,Jianzhong Su, Zhihong Wu, Nan Wu, Pengfei Liu, Xinjian Yang*.Whole-exomesequencing reveals known and novel variants in a cohort of intracranialvertebral-basilar artery dissection (IVAD).. journal of human genetics.2018,63(11):1119-1128.SCI

40. Miao Li,Jie Wang, Jian Liu, Conghai Zhao, Xinjian Yang*.Hemodynamics in RupturedIntracranial Aneurysms with Known Rupture Points. World Neurosurgery.2018,118:e721-e726..SCI

41. JunfanChen, Jian Liu, Yisen Zhang, Zhongbin Tian, Kun Wang, Ying Zhang,Shiqing Mu,Ming Lv, Peng Jiang, ChuanZhi Duan, Hongqi Zhang, Yan Qu, Min He, and XinjianYang*.China Intracranial Aneurysm Project (CIAP): protocol for a registry studyon a multidimensional prediction model for rupture risk of unrupturedintracranial aneurysms. journal of translational medicine. 2018,16(1）:263.SCI

42. 丁兴欢#,王坤,张倩倩,杨新健*.全外显子组测序技术探寻家族性颅内动脉瘤致病基因的研究进展. 中国微侵袭神经外科杂志.2018,23(10):470-474.核心期刊

43. Kun Wang#,Zhongbin Tian#, Junfan Chen, Jian Liu, Yang Wang, Hongqi Zhang, Jun Wang, YisenZhang,* and Xinjian Yang*.Risk Factors of Recurrence after Stent(s)-AssistedCoiling of Intracranial Vertebrobasilar Dissecting Aneurysms: A MulticenterStudy. Frontiers in Neurology. 2017,8:482.SCI

44. Tian Z,Chen J, Zhang Y, Liu J, Wang Y, Sui B*, Yang X*.Quantitative Analysis ofIntracranial Vertebrobasilar Dissecting Aneurysm with Intramural Hematoma AfterEndovascular Treatment Using 3-T High-Resolution Magnetic Resonance Imaging..World Neurosurgery. 2017,108:236-243.SCI

45. Jian Liu,Yisen Zhang, Anxin Wang, Ying Zhang, Yiying Li, Xinjian Yang*.Haemodynamicanalysis for recanalisation of intracranial aneurysms after endovasculartreatment: an observational registry study in China. BMJ open.2017,7:e014261.SCI

46. YisenZhang,Ming Yang,Hongqi Zhang,Xiaolong Zhang,Youxiang Li,Chuhan Jiang,JianLiu,Xinjian Yang*.Stent-Assisted Coiling May Prevent the Recurrence of VerySmall Ruptured Intracranial Aneurysms: A Multicenter Study. World Neurosurgery.2017,100:22-29.SCI

47. Yisen Zhang,Zhongbin Tian,BinbinSui,Yang Wang,Jian Liu,Miao Li,Youxiang Li,Chuhan Jiang,XinjianYang*.Endovascular Treatment of Spontaneous Intracranial Fusiform andDissecting Aneurysms: Outcomes Related to Imaging Classification of 309 Cases.World Neurosurgery. 2017,98:444-455.SCI

48. YisenZhang,Binbin Sui,Jian Liu,Yang Wang,Zhongbin Tian,Junfan Chen,ZhongxueWu,Xinjian Yang*.Aneurysm wall enhancement on magnetic resonance imaging as arisk factor for progression of unruptured vertebrobasilar dissecting aneurysmsafter reconstructive endovascular treatment. Journal of Neurosurgery.2017,10.3171/2016.11.JNS162433.:epub.SCI

49. QianqianZhang,Linkai Jing,Jian Liu,Kun Wang,Ying Zhang,Nikhil Paliwa,Hui Meng,YangWang,Shengzhang Wang,Xinjian Yang*.Predisposing factors for recanalization ofcerebral aneurysms after endovascular embolization: a multivariate study.Journal of neurointerventional surgery.2017,10.1136/neurintsurg-2017-013041:epub.SCI

50. 杨新健*，高培毅，隋滨滨，张义森.颅内动脉夹层影像学诊断专家共识. 中华神经外科杂志. 2016,32(11):1085-1094.核心期刊

51. YingZhang,Linkai Jing,Jian Liu,Chuanhui Li,Jixing Fan,Shengzhang Wang,HaiyunLi,Xinjian Yang*.Clinical, morphological, and hemodynamic independentcharacteristic factors for rupture of posterior communicating artery aneurysms.Journal of neurointerventional surgery. 2016,8(8):808-12.SCI

52. LinkaiJing, Jian Liu, Ying Zhang, Nikhil Paliwal, Hui Meng, Shengzhang Wang, XinjianYang*.Analysis of Multiple Intracranial Aneurysms with Different Outcomes inthe Same Patient After Endovascular Treatment. World Neurosurgery.2016,91:399—408.SCI

53. Jian Liu,Linkai Jing, Chao Wang, Ying Zhang, Xinjian Yang*.Recanalization, Regrowth, andDelayed Rupture of a Previously Coiled Unruptured Anterior Communicating ArteryAneurysm: A Longitudinal Hemodynamic Analysis. World Neurosurgery.2016,89:726.e5–726.e10.SCI

54. Chao Wang,Zhongbin Tian, Jian Liu, Linkai Jing, Nikhil Paliwal, Shengzhang Wang, YingZhang, Jianping Xiang, Adnan H. Siddiqui, Hui Meng, Xinjian Yang*.Hemodynamicalterations after stent implantation in 15 cases of intracranial aneurysm. ActaNeurochirurgica. 2016,158(4):811-819.SCI

55. YisenZhang,Yanmin Wang,Binbin Sui,Youxiang Li,Shiqing Mu,Ying Zhang,ZhongxueWu,Xinjian Yang*.Magnetic Resonance Imaging Follow-Up of Large or GiantVertebrobasilar Dissecting Aneurysms After Total Embolization on Angiography.World Neurosurgery. 2016,91:218-27.SCI

56. ZhongbinTian,Yisen Zhang,Linkai Jing,Jian Liu,Ying Zhang,Xinjian Yang*.Rupture RiskAssessment for Mirror Aneurysms with Different Outcomes in the Same Patient .Frontiers in Neurology. 2016,7:219.SCI

57. JianLiu,Yisen Zhang,Yang Wang,Shiqing Mu,Xinjian Yang*.Stenting After Coiling Usinga Single Microcatheter for Treatment of Ruptured Intracranial FusiformAneurysms with Parent Arteries Less Than 1.5 mm in Diameter. WorldNeurosurgery. 2016,10.1016/j.wneu.2016.12.135:epub.SCI

58. Chao Wang,Zhongbin Tian,JianLiu,Linkai Jing,Nikhil Paliwal,Shengzhang Wang,Ying Zhang,Jianping Xiang,AdnanH. Siddiqui,Hui Meng,Xinjian Yang*.Flow diverter effect of LVIS stent oncerebral aneurysm hemodynamics: a comparison with Enterprise stents and thePipeline device. . journal of translational medicine. 2016,14(1):199.SCI

59. Yisen Zhang,Zhongbin Tian,LinkaiJing,Ying Zhang,Jian Liu#,Xinjian Yang*.Bifurcation type and larger low sheararea are associated with rupture status of very small intracranial aneurysms.Frontiers in Neurology. 2016,7:169.SCI

60. Yi-SenZhang,Shuo Wang,Yang Wang,Zhong-Bin Tian,Jian Liu,Kun Wang,Jun-FanChen,Xin-Jian Yang*.Treatment for spontaneous intracranial dissecting aneurysmsin childhood: a retrospective study of 26 cases. Frontiers inNeurology. 2016,7:224.SCI

61. Jian Liu,LinkaiJing,Ying Zhang,Ying Song,Yang Wang,Chuanhui Li,Yanmin Wang,Shiqing Mu,NikhilPaliwal,Hui Meng,Italo Linfante,Xinjian Yang*.Successful Retreatment ofRecurrent Intracranial Vertebral Artery Dissecting Aneurysms afterStent-assisted Coil Embolization: A Self-controlled Hemodynamic Analysis. WorldNeurosurgery. 2016,97:344-350.SCI

62. QianqianZhang,Zhuangyuan Meng,Ying Zhang,Kai Yao,Jian Liu,Yisen Zhang,LinkaiJing,Xinjian Yang*,Nikhil Paliwal,Hui Meng,Shengzhang Wang#.Phantom-basedexperimental validation of fast virtual deployment of self-expandable stentsfor cerebral aneurysms. BioMedical Engineering OnLine. 2016,15(Suppl 2):125.SCI

63. YisenZhang,Linkai Jing,Ying Zhang,Jian Liu#,Xinjian Yang*.Low wall shear stress isassociated with the rupture of intracranial aneurysm with known rupture point:case report and literature review.. BMC Neurology. 2016,16(1):231.SCI

64. JianLiu,Linkai Jing,Chao Wang,Nikhil Paliwal,Shengzhang Wang,Ying Zhang,JianpingXiang,Adnan H Siddiqui,Hui Meng,Xinjian Yang*.Effect of hemodynamics on outcomeof subtotally occluded paraclinoid aneurysms after stent-assisted coilembolization. Journal of neurointerventional surgery. 2016,8(11):1140-1147.SCI

65. Liu Jian,Jing Linkai, Wang Chao, Paliwal Nikhil, Wang Shengzhang, Zhang Ying, XiangJianping, Siddiqui Adnan H, Meng Hui, Yang Xinjian*.Effect of hemodynamics onoutcome of subtotally occluded paraclinoid aneurysms after stent-assisted coilembolization. J Neurointerv Surg. 2015,10.1136/neurintsurg-2015-012050:epub.SCI

66. Liu Jian,Fan Jixing#, Xiang Jianping, Zhang Ying, Yang Xinjian*.Hemodynamiccharacteristics of large unruptured internal carotid artery aneurysms prior torupture: a case control study. J Neurointerv Surg.2015,10.1136/neurintsurg-2014-011577:epub.SCI

67. ZhangYing, Jing Linkai, Liu Jian, Li Chuanhui, Fan Jixing, Wang Shengzhang, LiHaiyun, Yang Xinjian*.Clinical, morphological, and hemodynamic independentcharacteristic factors for rupture of posterior communicating artery aneurysms.J Neurointerv Surg. 2015,10.1136/neurintsurg-2015-011865:epub.SCI

68. FanJixing, Wang Yanmin, Liu Jian, Jing Linkai, Wang Chao, Li Chuanhui, YangXinjian*, Zhang Ying*.Morphological-hemodynamic characteristics of intracranialbifurcation mirror aneurysms. World Neurosurgery.2015,10.1016/j.wneu.2015.02.038:epub.SCI

69. LiChuanhui, Li Youxiang, Jiang Chuhan, Wu Zhongxue, Wang Yang, Yang Xinjian*.Stentalone treatment for dissections and dissecting aneurysms involving the basilarartery. J Neurointerv Surg. 2015,7(1):50-55.SCI

70. Wang Y, Yang X*, Youxiang L,Shiqing M, Chuhan J, Zhongxue W, Kocer N.Treatment of symptomatic fusiformaneurysm in basilar artery by stenting following coiling technique. TurkNeurosurg. 2014,24(1):44-7.SCI

71. Song Ying,Wang Yang, Li Chuanhui, Wang Yanmin, Mu Shiqing, Yang Xinjian*.Retreatment andOutcomes of Recurrent Intracranial Vertebral Artery Dissecting Aneurysms afterStent Assisted Coiling: A Single Center Experience. PLoS One.2014,9(11):e113027.SCI

72. ZhangYing, Yang Xinjian*, Wang Yang, Liu Jian, Li Chuanhui, Jing Linkai, WangShengzhang, Li Haiyun.Influence of morphology and hemodynamic factors onrupture of multiple intracranial aneurysms: matched-pairs ofruptured-unruptured aneurysms located unilaterally on the anterior circulation.BMC Neurology . 2014,14(1):1059.SCI

73. Wang Y, Lou X, Li Y, Sui B, Sun S,Li C, Jiang P, Siddiqui A, Yang X*.Imaging investigation of intracranialarterial dissecting aneurysms by using 3 T high-resolution MRI and DSA: fromthe interventional neuroradiologists' view. Acta Neurochir (Wien).2014,156(3):515-25.SCI

74. LiChuanhui, Li Youxiang, Jiang Chuhan, Wu Zhongxue, Wang Yang, YangXinjian*.Remission of neurovascular conflicts in the cerebellopontine angle ininterventional neuroradiology. J Neurointerv Surg.2014,10.1136/neurintsurg-2014-011500:epub.SCI

75. Liu J,Xiang J, Zhang Y, Wang Y, Li H, Meng H, Yang X*.Morphologic and hemodynamicanalysis of paraclinoid aneurysms: ruptured versus unruptured. J NeurointervSurg. 2014,6(9):658-663.SCI

76. Wang Y, LiY, Jiang C, Wu Z, Jiang F, Meng H, Siddiqui AH, Yang X*.Could the types ofparaclinoid aneurysm be used as a criterion in choosing endovascular treatment?Neuro-radiologists' view.. Acta Neurochir (Wien). 2013,155(11):2019-27.SCI

77. Wang Y, LiY, Jiang C, Jiang F, Meng H, Siddiqui AH, Yang X*.Endovascular treatment ofparaclinoid aneurysms: 142 aneurysms in one centre. J Neurointerv Surg.2013,5(6):552-6.SCI

78. 汪阳, 刘健, 杨新健*.颈内动脉床突旁动脉瘤影像学分类探讨. 中国现代神经疾病杂志. 2013,13(3):183-188.核心期刊

79. Chuanhui Li，Shengzhang Wang，Jialiang Chen，Hongyu Yu，Ying Zhang，Fan Jiang，Shiqing Mu，Haiyun Li，Xinjian Yang*.Influence of hemodynamics onrecanalization of totally occluded intracranial aneurysms: a patient-specificcomputational fluid dynamic simulation study. Journal of Neurosurgery.2012,117(2):276-83.SCI

二、申请专利5项。

1.   发明名称：一种预测颅内动脉瘤信息的方法、装置以及设备 发明人：杨新健；刘健；张义森；王坤；朱巍；张莹；千舒；宋凌；印胤；杨光明；专利号：ZL202110507563.X

2.   实用新型名称：一种应用千右侧锁骨下动脉起始部狭窄的治疗仪器；发明人：张义森；杨新健；专利号： ZL 201921212464.3

3.   发明名称：LEMD3及其突变在BAVM诊治中的应用；发明人：王坤；杨新健；吴南；赵森；吴志宏；专利号：ZL201810598830.7

4.   发明名称：血管支架快速释放的模拟方法、装置、计算机设备和存储介质；发明人：金彤伯；刘健；汪阳；冷晓畅；杨新健，向建平；专利号：ZL202010623464.3

5.   发明名称： 与I3AVM相关的基因标志物及其突变；发明人：杨新健；王坤；吴南；赵森；吴志宏；专利号： ZL 2018l0598796.3

三、获奖情况

1. 出血性脑血管病血管内治疗研究创新团队科技部2016年创新人才推进计划重点领域创新团队 201701

2. 颅内动脉瘤的病理生理及血流动力学研究华夏医学科技奖 三等奖 201301

3. 颅内动脉瘤的介入治疗中华医学科技奖 三等奖 201212

4. 颅内动脉瘤的介入治疗教育部科学技术进步奖(推广类) 二等奖 201202

5. 全国医药科学技术奖 脑动脉瘤介入治疗 一等奖 200911

6. 北京市科技新星 北京市科技新星 200301

三、主编或副主编的著作/译著

1. 《经皮椎体成形术》,主编,人民卫生出版社,200411