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长期从事卫生化学的教学与纳米材料检测技术研究。主持国家自然基金项目4项,北京市自然科学基金,北京市教委项目3项;在国内外学术刊物上已发表相关论文50余篇,其中在Part.Fibre. Toxicol. ,Chem. Comm.等杂志发表SCI论文50余篇;授权国家发明专利2项,多次参加国际学术会议并进行学术交流。作为教材主编或副主编,完成编写了《卫生化学》、《仪器分析实验》、《预防医学》(英文版)等国家级规划教材6部。兼任中国检验检疫学会理事、中国环境诱变剂学会致癌专业委员会常委、中国环境诱变剂学会活性氧生物学效应专业委员会委员。国家卫生健康委人才交流服务中心高级人才评价项目专家 。
团队现有教授1人,副教授1人,博士研究生3人,硕士研究生2人。与中国医学科学院药物研究所和中国疾病预防控制中心有很好的研究合作。
(1)国家自然科学基金面上项目 生物基质中多分散纳塑料分离检测体系的构建及其在毒代动力学/毒效学研究中的应用(NO82173569)主持、2022/01-2025/12
(2)国家自然科学基金面上项目:细胞外囊泡异质性亚群快速分离方法的建立及在超细颗粒物致心血管损伤研究中的应用(NO81872667)主持、2019/01-2022/12
(3)北京市自然科学基金面上项目:褪黑素及其联合青霉胺对铜负荷Wilson病模型大鼠的排铜作用与治疗机理研究(NO 7222241)主持、2022/01-2024/12
重要学术论文
(1)Ling Kong, Zhen Mao, Shiyu He, Kexin Li, Lihong Zhou, Xiaodan Zhang, Peili Huang*.PM2.5 induces alterations in gene expression proffle of platelet-derived extracellular vesicles and mediates cardiovascular injury in rats.Ecotoxicology and Environmental Safety.2023,262,115341.
(2)Shiyu He, Jingran Wang, Lihong Zhou, Tianjiang Jia , Zhen Mao , Xiaodan Zhang , Lingyan Zhang, Ji Wang, Man Yang, Peili Huang *Short term exposure to polystyrene nanoplastics in mice evokes self-regulation of glycolipid metabolism.Ecotoxicology and Environmental Safety.2023,256,114906.
(3)Lingyan Zhang,Yingting Wu,Xingling Luo,Tianjiang Jia,Kexin Li,Lihong Zhou,Zhen Mao,Peili Huang*. A novel insight into mechanism of derangement of coagulation balance: interactions of quantum dots with coagulation‑related proteins. Particle and Fibre Toxicology. 2022,19(17)1-16.
(4)Lihong Zhou,Yamin Xiong,Hui Wang,Aihong Yin,Xueying Zhang,Huiling Li, Qinghua Fu,Peili Huang*. Target-triggered DNAzyme walker with 3D walking unit for copper species sensing in serum: A multivalent binding strategy forimproving the detection performance.Sensors & Actuators: B. Chemical.2021,334:129589.
(5)Xing-ling Luo,Ying-ting Wu,Ling-Yan Zhang,Ke-xin Li,Tian-jiang Jia,Yi Chen,Li-hong zhou,Peii Huang*. An effective solution to simultaneously analyze size, mass and number concentration of polydisperse nanoplastics in a biological matrix:asymmetrical flow field fractionation coupled with a diode array etector and multiangle light scattering.RSC Advances.2021,11: 12902–12906.
(6)Yamin Xiong,Lihong Zhou; Xiaoxia Peng, Huiling Li,Hui Wang,Leiliang He*,Peili Huang*. A specific short peptide-assisted enhanced chemiluminescence resonance energy transfer(CRET) for label free and ratiometric detection of copper ions in complex samples. Sensors & Actuators: B. Chemical.2020, 320:128411.
(7)Ling Kong,Kexin Li,Lifang Gao,Aihong Yin,Lihong Zhou,Gesi Teng,Peili Huang*. Mediating effects of platelet-derived extracellular vesicles on PM2.5-induced vascular endothelial injury. Ecotoxicology and Environmental Safety. 2020, 198:110652.
(8)Yamin Xiong,Lihong Zhou,Hui Wang,Huiling Li,Yue Hu,Peijun Meng,Xueying Zhang,Peili Huang*. Rapid laboratory diagnosis of Wilson’s disease: One-step simultaneous detection of exchangeable copper and ceruloplasmin in serum based on nanotechnology. Sensors & Actuators: B. Chemical. 2019,281: 713–719.
(9)Peijun Meng,Yamin Xiong,Yingting Wu,Yue Hu,Hui Wang,Yuanfeng Pang,Shuqing Jiang,Sihai Han,Peili Huang*. A novel strategy to evaluate the degradation of quantum dots: identification and quantification of CdTe quantum dots and corresponding ionic species by CZE-ICP-MS. Chemical Communications. 2018, 54: 5342-5345.
(10)Xiong YM, Meng PJ, Li HL, Hu Y, Zhou LH, Jiang SQ, Pang YF, Li SJ, Huang PL* . Dual signal amplification strategy for high-sensitivity detection of copper species in bio-samples with a tunable dynamic range. Chemical Communications. 2018,54: 2542-2545.
授权国家发明专利
(1)黄沛力,熊亚敏. 一种血清中可交换铜和铜蓝蛋白一步同时检测用试剂盒、制备方法及应用(CN 108802360 B)2023.8.25
(2)黄沛力,孟佩俊. 一种对CdTeQDs及其降解或代谢产物同时定量检测的方法及其应用 (CN 107907583 B)2022.4.26
(3)黄沛力,熊亚敏.一种金属离子检测用探针、试剂盒、制备方法、应用(CN 107860765 B)2020.8.4
主编或副主编的著作/译著
(1)副主编 《现代卫生化学 》 人民卫生出版社,ISBN978-7-117-30957-8 2021.2
重要奖项
(1)首都医科大学科学技术奖三等奖 2023年度
(2)首都医科大学科学技术奖三等奖 2021年度
(3)首都医科大学优秀教学奖 2019年度
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