本研究团队主要研究方向为生殖毒理，此外，也开展了一些代谢毒性等方面的研究。团队实行导师负责制、年轻老师参与指导、以博士研究生和硕士研究生为主体的模式开展科研工作。

先后主持和参与省部级以上科研项目和人才项目近20项，其中主持国家自然科学基金8项。以下为近五年主持和参与的省部级以上科研项目：

1. 国家自然科学基金项目，32171492,支持细胞在环境十溴联苯醚致小鼠精子发生障碍中的调控作用 ，直接费用：59.00万元，2022/01-2025/12, 在研，主持。

2. 国家自然科学基金项目，31971415，减数分裂调控因子和组蛋白泛素化途径在环境十溴联苯醚致小鼠精子发生障碍中的调控作用，直接费用：58.00万元，2020/ 01-2023/12， 在研，主持。

3. 国家自然科学基金项目，31770441,环境多溴联苯醚对小鼠精子发生过程的影响及其机制研究，直接费用：55.00万元，2018/ 01-2021/12，已结题，主持。.

4. 国家重点研发计划重点专项, 2017YFC0211600，大气污染对呼吸和心血管系统健康影响的早期识别技术，2017/07-2020/12，2967万元，已结题，参加。

5．国家自然科学基金委国际(地区)合作与交流项目（中英重大国际合作项目）（APIC-ESTEE），81571130090， 北京大气污染对心肺疾病影响的暴露科学、毒理基因组学和环境流行病学综合研究， 2016/01-2019/12， 500万，已结题，参加。

6．北京市教委科技发展计划暨北京市自然科学基金重点项目，KZ201510025028，环境纳米二氧化硅对生精过程的影响及其机制研究，2015/01-2017/12, 50万，已结题，主持。

7．国家自然科学基金项目，31370430, 杀虫剂硫丹对大鼠凝血和抗凝血系统的影响及其机制研究, 2014/01-2017/12,  80万, 已结题，主持。

先后主持和参与省部级以上科研项目和人才项目近20项，其中主持国家自然科学基金9项。以下为近五年主持的省部级以上科研项目：

1. 国家自然科学基金委国际(地区)合作与交流项目(内地-澳门)，32261160641，环境纳米颗粒暴露对生殖发育和功能的影响及其调 控机制研究，直接费用：165.00万元，2023/01-2025/12, 在研，主持。

2. 国家自然科学基金项目，32171492,支持细胞在环境十溴联苯醚致小鼠精子发生障碍中的调控作用 ，直接费用：59.00万元，2022/01-2025/12, 在研，主持。

3. 国家自然科学基金项目，31971415，减数分裂调控因子和组蛋白泛素化途径在环境十溴联苯醚致小鼠精子发生障碍中的调控作用，直接费用：58.00万元，2020/ 01-2023/12， 在研，主持。

4. 国家自然科学基金项目，31770441,环境多溴联苯醚对小鼠精子发生过程的影响及其机制研究，直接费用：55.00万元，2018/ 01-2021/12，已结题，主持。

5. 国家重点研发计划重点专项, 2017YFC0211600，大气污染对呼吸和心血管系统健康影响的早期识别技术，2017/07-2020/12，2967万元，已结题，参加。

6．北京市教委科技发展计划暨北京市自然科学基金重点项目，KZ201510025028，环境纳米二氧化硅对生精过程的影响及其机制研究，2015/01-2017/12, 50万，已结题，主持。

近年发表的部分SCI论文：

1. Guiqing Zhou#,Ji Wang#, Lihua Ren, Jianhui Liu, Xiangyang Li , Yue Zhang , YujianSang, Leqiang Gao, Yanbo Li, Zhiwei Sun, Xianqing Zhou*. Silicananoparticles suppressed the spermatogenesis via downregulation of miR-450b-3pby targeting Layilin in spermatocyte of mouse. Environmental Pollution,Environmental Pollution, 2023, 318: 120864. (5 year IF=10.3659，Q1)

2. Yue Zhang, Jianhui Liu, Xiangyang Li,Guiqing Zhou, Yujian Sang, Mingyuan Zhang , Leqiang Gao, Jinglong Xue, MoxuanZhao, Huanling Yu*, Xianqing Zhou*. Dietary selenium excess affectedspermatogenesis via DNA damage and telomere-related cell senescence and apoptosisin mice. Food and Chemical Toxicology，2023，171：113556. （共通讯）

3. Xiangyang Li^#,Yue Zhang^#, Leqiang Gao, Xiaodi Yang, Guiqing Zhou, Yujian Sang,Jinglong Xue, Zhixiong Shi^⁎ , Zhiwei Sun, Xianqing Zhou^⁎.BDE-209 induced spermatogenesis disorder by inhibiting SETD8/ H4K20me1related histone methylation in mice. Science of the Total Environment，2023，864：161162.. (5 year IF=10.237，Q1)

4. JianhuiLiu, Jing Huang, Leqiang Gao, Yujian Sang, Xiangyang Li, Guiqing Zhou, LinlinCao, Hong Lu, Xianqing Zhou*, Lihua Ren*.Maternalexposure to PM2.5 disrupting offspring spermatogenesis through induced sertolicells apoptosis via inhibin B hypermethylation in mice. Ecotoxicology andEnvironmental Safety，2022, 241：113760. (5 year IF=7.2845)

5. Leqiang Gao# , Yue Zhang#, Jianhui Liu , Xiangyang Li,Yujian Sang, Guiqing Zhou, Jinglong Xue , Li Jing , Zhixiong Shi, Jialiu Wei *, Xiangfeng Lu, Xianqing Zhou*..Fat mass and obesity-associated gene(FTO) hypermethylation induced by decabromodiphenyl ethane causing cardiacdysfunction via glucolipid metabolism disorder. Ecotoxicology and EnvironmentalSafety, 2022, 237:113534. (5 year IF=7.2845)

6.Yupeng Zhu#，Li Jing#，Xiangyang Li，GuiqingZhou，Yue Zhang，Yujian Sang，LeqiangGao，Sitong Liu，Zhixiong Shi，ZhiweiSun，Wei Ge*，Xianqing Zhou*. Decabromodiphenyl ether-inducedPRKACA hypermethylation contributed to glycolipid metabolism disorder viaregulating PKA/AMPK pathway in rat and L-02 cells. Environmental Toxicology andPharmacology，2022，90：103808. (5 year IF=4.9521)

7. MingmingQin, Qingping Xie, Kun Wu, Xianqing Zhou, Wei Ge*. Loss of Noboxprevents ovarian differentiation from juvenile ovaries in zebrafish, Biologyof Reproduction, 2022;, ioac036, https://doi.org/10.1093/biolre/ioac036 (5 year IF=4.5216)

8. Xiangyang Li, Jianhui Liu, Guiqing Zhou, Yujian Sang, Yue Zhang, LiJing, Zhixiong Shi, Xianqing Zhou*,Zhiwei Sun. BDE-209 and DBDPE induce male reproductive toxicity throughtelomere-related cell senescence and apoptosis in SD rat. EnvironmentInternational, 2021, 146: 106307. (5 year IF=13.2380)

9. Yupeng Zhu#, Li Jing#, Xiangyang Li, Dan Zheng,Guiqing Zhou, Yue Zhang, Yujian Sang, Zhixiong Shi, Zhiwei Sun, XianqingZhou*. Decabromodiphenyl ether disturbs hepatic glycolipid metabolism byregulating the PI3K/AKT/GLUT4 and mTOR/PPARγ/RXRα pathway in mice and L02cells. Science of The Total Environment, 2021, 763: 142936. (5 yearIF=10.237)

10. Guiqing Zhou, Jianhui Liu, Xiangyang Li, Yujian Sang, Yue Zhang,Leqiang Gao, Ji Wang , Yang Yu, Wei Ge, Zhiwei Sun, Xianqing Zhou*.Silica nanoparticles inducing the apoptosis via microRNA-450b-3p targetingMTCH2 in mice and spermatocyte cell. Environmental Pollution，2021，277：116771.(5 yearIF=10.3659)

11.Hua Qin, Jiao Chen,Yang Li,Lifang Gao, JiWang, Guangbo Qu, ManYang*, XianqingZhou, Zhiwei Sun. Inflammatory response induced by black phosphorusnanosheets in mice and macrophages. Science of The Total Environment, 2021,782: 146860. (5 year IF=10.2371)

12. Xiangyang Li#, Yue Zhang#,Xiaomin Dong , Guiqing Zhou , Yujian Sang , Leqiang Gao, Xianqing Zhou*,Zhiwei Sun. DNA methylation changes induced by BDE-209 are related to DNAdamage response and germ cell development in GC-2spd. Journal of environmentalsciences, 2021, 109: 161-170.  (5 year IF=6.1275)

13.Jianhui Liu, Xiangyang Li, Guiqing Zhou, Yue Zhang, Yujian Sang, JiWang, Yanbo Li, Wei Ge, Zhiwei Sun, Xianqing Zhou*. Silica nanoparticlesinhibiting the differentiation of round spermatid and chromatin remodeling ofhaploid period via MIWI in mice. Environmental Pollution, 2021, 284, 117446. (5year IF=10.36591)

14. Yue Zhang#，Xiangyang Li#, Guiqing Zhou, Yujian Sang, Leqiang Gao, Shuqin Jiang*, Zhixiong Shi, Wei Ge, Zhiwei Sun, Xianqing Zhou*. Decabromodiphenyl ether inducesmale reproductive toxicity by activating mitochondrial apoptotic pathwaythrough glycolipid metabolism dysbiosis. Chemosphere, 2021, 285: 131512. (5 year IF=8.5197)

15. Li Jing, Yanmin Sun, Ji Wang, Xianqing Zhou,Zhixiong Shi*. Oxidative stress and endoplasmic reticulum stress contributed tohepatotoxicity of decabromodiphenyl ethane (DBDPE) in L-02 cells. Chemosphere，2021，286(2022)：131550. (5 year IF=8.5197)

16. Guiqing Zhou #, Lihua Ren#, HaipingYin , Jianhui Liu, Xiangyang Li , Ji Wang , Yanbo Li , Yujian Sang, YanzhiZhao*, Xianqing Zhou*, Zhiwei Sun. The alterations of miRNA and mRNAexpression profile and their integration analysis induced by silicananoparticles in spermatocyte cells. NanoImpact, 2021, 23 :100348. (5 year IF=6.4942)

17. Yujian Sang, Jianhui Liu, Xiangyang Li, Guiqing Zhou, Yue Zhang,Leqiang Gao, Yanzhi Zhao*, Xianqing Zhou*. The effect of SiNPs on DNAmethylation of genome in mouse spermatocytes, Environmental Science andPollution Research, 2021, 28: 43684-43697. (5 year IF=5.0530)

18. Lianshuang Zhang#, Jialiu Wei#, Junchao Duan#,Caixia Guo, Jin Zhang, Lihua Ren, Jianhui Liu, Yanbo Li*, Zhiwei Sun, Xianqing Zhou*. Silica Nanoparticlesexacerbates reproductive toxicity development in high-fat diet-treated Wistarrats. Journal of Hazardous Materials, 2020, 384: 121361. (5 year IF=12.9845)

19. Lihua Ren, Jing Huang, Jialiu Wei, Zang Yu, Yang Zhao, Shaowei Wu,Xiaohong Zhao, Xianqing Zhou, Zhiwei Sun, Hong Lu*. Maternal exposure tofine particle matters cause autophagy via UPR-mediated PI3K-mTOR pathway intesticular tissue of adult male mice in offspring. Ecotoxicology andEnvironmental Safety, 2020, 189: 109943. (5 year IF=7.2845)

20. Yanmin Sun, Yuwei Wang, Baolu Liang, Tian Chen, Dan Zheng, XuezhenZhao, Li Jing*, Xianqing Zhou, Zhiwei Sun, Zhixiong Shi*. Hepatotoxicityof decabromodiphenyl ethane (DBDPE) and decabromodiphenyl ether (BDE-209) in28-day exposed Sprague-Dawley rats. Science of the Total Environment, 2020,705: 135783. (5 year IF=10.237)

21. Jialiu Wei, Jianhui Liu, Lianshuang Zhang, Yupeng Zhu, Xiangyang Li, GuiqingZhou, Yanzhi Zhao*, Zhiwei Sun, Xianqing Zhou*. Endosulfan inducescardiotoxicity through apoptosis via unbalance of pro-survival andmitochondrial-mediated apoptotic pathways. Science of the Total Environment,2020, 727: 138790. (5 year IF=10.237)

22. Jianhui Liu, Xiangyang Li, Guiqing Zhou, Yujian Sang, Yue Zhang,Yanzhi Zhao, Wei Ge, Zhiwei Sun, Xianqing Zhou*. Silica nanoparticlesinduce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis andRNF8-ubH2A/ubH2B pathway in mice. Environmental Pollution, 2020, 265: 114974. (5year IF=10.3659)

23. Lihua Ren, Jianhui Liu, Jialiu Wei, Yefan Du, Kaiyue Zou, YongyangYan, Zhihao Wang, Linruo Zhang, Tong Zhang, Hong Lu, Xianqing Zhou*,Zhiwei Sun. Silica nanoparticles induce unfolded protein reaction mediatedapoptosis in spermatocyte cells. Toxicology Research, 2020, 9(4): 454-460. (5year IF=2.9500)

24. Yupeng Zhu, Xiangyang Li, Jianhui Liu, Guiqing Zhou, Yang Yu*, LiJing, Zhixiong Shi, Xianqing Zhou*, Zhiwei Sun. The effects ofdecabromodiphenyl ether on glycolipid metabolism and related signaling pathwaysin mice. Chemosphere, 2019, 222: 849-855. (5 year IF=8.5197)

25. Lihua Ren#, Jin Zhang#, Ji Wang, Jialiu Wei,Jianhui Liu, Xiangyang Li, Yupeng Zhu, Yanbo Li, Caixia Guo, Junchao Duan,Zhiwei Sun, Xianqing Zhou*. Silica nanoparticles induce spermatocytecell apoptosis 2 through microRNA-2861 targeting death receptor pathway.Chemosphere, 2019, 228: 709-720. (5 year IF=8.5197)

26. Jianhui Liu#, Jin Zhang#, Lihua Ren, JialiuWei, Yupeng Zhu, Junchao Duan, Li Jing, Zhiwei Sun*, Xianqing Zhou*.Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondriaapoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.Ecotoxicology and Environmental Safety, 2019, 180: 280–287. (5 yearIF=7.2845)

27. Yanbo Li, Ru Ma, Xiaoying Liu, Yi Qi, Alimire Abulikemul, XinyingZhao, Huawei Duan, Xianqing Zhou, Caixia Guo*, Zhiwei Sun*. Endoplasmicreticulum stress-dependent oxidative stress mediated vascular injury induced bysilica nanoparticles in vivo and in vitro. NanoImpact, 2019, 14: 100169. (5year IF=6.4942)

28. Xiangyang Li, Yupeng Zhu, Chonghai Zhang, Jianhui Liu, Guiqing Zhou,Li Jing, Zhixiong Shi, Zhiwei Sun, Xianqing Zhou*. BDE-209 induces malereproductive toxicity via cell cycle arrest and apoptosis mediated by DNAdamage response signaling pathways. Environmental Pollution, 2019, 255: 113097. (5 year IF=10.3659)

29. Lihua Ren#, Jianhui Liu#, Jin Zhang, Ji Wang,Jialiu Wei, Yanbo Li, Caixia Guo, Zhiwei Sun, Xianqing Zhou*. Silicananoparticles induce spermatocyte cell autophagy through microRNA-494 targetingAKT in GC-2spd cells. Environmental Pollution, 2019, 255: 113172.  (5 year IF=10.3659)

30. Yuwei Wang, Tian Chen, Yanmin Sun, Xuezhen Zhao, Dan Zheng, Li Jing*,Xianqing Zhou, Zhiwei Sun, Zhixiong Shi*. A comparison of the thyroiddisruption induced by decabrominated diphenyl ethers (BDE-209) and decabromodiphenylethane (DBDPE) in rats. Ecotoxicology and Environmental Safety, 2019, 174:224-235. (5 year IF=7.2845)

31. Li Jing, Yanmin Sun, Yuwei Wang, Baolu Liang, Tian Chen, Dan Zheng,Xuezhen Zhao, Xianqing Zhou, Zhiwei Sun, Zhixiong Shi*. Cardiovasculartoxicity of decabrominated diphenyl ethers (BDE-209) and decabromodiphenylethane (DBDPE) in rats. Chemosphere, 2019, 223: 675-685. (5 year IF=8.5197)

32. Jiandi Wang, Yuwei Wang, Zhixiong Shi*, Xianqing Zhou, ZhiweiSun. Legacy and novel brominated flame retardants in indoor dust from Beijing,China: Occurrence, human exposure assessment and evidence for PBDEsreplacement. Science of The Total Environment, 2018, 618: 48-59. (5 yearIF=10.237)

33. Caixia Guo, Ru Ma, Xiaoying Liu, Tian Chen, Yang Li, Yang Yu, JunchaoDuan, Xianqing Zhou, Yanbo Li*, Zhiwei Sun*. Silica nanoparticlespromote oxLDL-induced macrophage lipid accumulation and apoptosis viaendoplasmic reticulum stress signaling. Science of The Total Environment, 2018,631-632: 570-579. (5 year IF=10.237)

34. Caixia Guo, Ji Wang, Li Jing, Ru Ma, Xiaoying Liu, Lifang Gao, LigeCao, Junchao Duan, Xianqing Zhou, Yanbo Li*, Zhiwei Sun. Mitochondrialdysfunction, perturbations of mitochondrial dynamics and biogenesis involved inendothelial injury induced by silica nanoparticles. Environmental Pollution,2018, 236: 926-936. (5 year IF=10.3659)

35. Jianhui Liu, Man Yang, Li Jing, Lihua Ren, Jialiu Wei,Feng Zhang, Junchao Duan, Xianqing Zhou*, Zhiwei Sun.Silica nanoparticle exposure inducing granulosa cell apoptosis and follicularatresia in female Balb/c mice. Environmental Science and Pollution Research,2018, 25: 3423-3434. (5 year IF=5.0530)

36. Jianhui Liu, Lihua Ren, Jialiu Wei, Jin Zhang, Yupeng Zhu,Xiangyang Li, Li Jing, Junchao Duan, Xianqing Zhou*,Zhiwei Sun. Fine particle matter disrupts the blood–testis barrier byactivating TGF-b3/p38 MAPK pathway and decreasing testosterone secretion inrat. Environmental Toxicology, 2018, 33(7): 711-719. (5 year IF=3.7470)

37. Jin Zhang#, Jianhui Liu#, Lihua Ren, JialiuWei, Junchao Duan, Lefeng Zhang*, Xianqing Zhou*, Zhiwei Sun. PM2.5induces male reproductive toxicity via mitochondrial dysfunction, DNA damageand RIPK1 mediated apoptotic signaling pathway. Science of the TotalEnvironment, 2018, 634: 1435–1444. (5 year IF=10.237)

38. Ji Wang, Yang Li, Junchao Duan, Man Yang, Yang Yu, Lin Feng, XiaozheYang, Xianqing Zhou, Zhendong Zhao*, Zhiwei Sun*. Silica nanoparticlesinduce autophagosome accumulation via activation of the EIF2AK3 and ATF6 UPRpathways in hepatocytes. Autophagy, 2018, 14(7): 1185-1200. (5 year IF=16.1425)

39. Jin Zhang#, Jianhui Liu#, Lihua Ren, JialiuWei, Feng Zhang, Yanbo Li, Caixia Guo, Junchao Duan, Zhiwei Sun, XianqingZhou*. Silica nanoparticles induce abnormal mitosis and apoptosis via PKC-δmediated negative signaling pathway in GC-2 cells of mice. Chemosphere, 2018,208: 942-950. (5 year IF=8.5197)

40. Caixia Guo, Ru Ma, Xiaoying Liu, Yinye Xia, Piye Niu, Junxiang Ma, XianqingZhou, Yanbo Li*, Zhiwei Sun. Silica nanoparticles induced endothelialapoptosis via endoplasmic reticulum stress-mitochondrial apoptotic signaling pathway.Chemosphere, 2018, 210: 183-192. (5 year IF=8.5197)

41. Yuwei Wang, Yanmin Sun, Tian Chen, Zhixiong Shi*, Xianqing Zhou,Zhiwei Sun, Lei Zhang, Jingguang Li*. Determination of polybrominated diphenylethers and novel brominated flame retardants in human serum by gaschromatography-atmospheric pressure chemical ionization-tandem massspectrometry. J Chromatogr B Analyt Technol Biomed Life Sci, 2018, 1099: 64-72.(5 year IF=3.1642)

42. Lianshuang Zhang, Jialiu Wei, Lihua Ren, JinZhang, Ji Wang, Li Jing, Man Yang, Yang Yu, Zhiwei Sun, Xianqing Zhou*. Endosulfaninduces autophagy and endothelial dysfunction via the AMPK/mTOR signalingpathway triggered by oxidative stress. Environmental Pollution, 2017, 220:843-852. (5 year IF=10.3659)

43. Jialiu Wei, Lianshuang Zhang, Lihua Ren, Jin Zhang, Yang Yu, Ji Wang,Junchao Duan, Cheng Peng, Zhiwei Sun, Xianqing Zhou*.Endosulfan induces proliferation inhibition through Notch signaling pathway in human umbilical vein endothelial cells.Environmental Pollution, 2017, 221: 26-36. (5 year IF=10.3659)

44. Ji Wang, Yongbo Yu, Ke Lu, Man Yang, Yang Li, Xianqing Zhou,Zhiwei Sun*. Silica nanoparticles induce autophagy dysfunction via lysosomalimpairment and inhibition of autophagosome degradation in hepatocytes.International Journal of Nanomedicine, 2017, 12: 809–825. (5 year IF=7.4194)

45. Jian Li#, Tian Chen#, Yuwei Wang, ZhixiongShi*, Xianqing Zhou, Zhiwei Sun, Dejun Wang*, Yongning Wu. Simple andfast analysis of tetrabromobisphenol A, hexabromocyclododecane isomers, andpolybrominated diphenyl ethers in serum using solid-phase extraction orQuEChERS extraction followed by tandem mass spectrometry coupled to HPLC andGC. Journal of Separation Science, 2017, 40: 709–716. (5 year IF=2.9040)

46. Lianshuang Zhang, Jialiu Wei, Lihua Ren, Jin Zhang, Man Yang*, LiJing, Ji Wang, Zhiwei Sun, Xianqing Zhou*. Endosulfan inducing apoptosisand necroptosis through activation RIPK signaling pathway in human umbilicalvascular endothelial cells. Environmental Science and Pollution Research, 2017,24: 215–225. (5 year IF=5.0530)

47. Fangzi Guo#, Ying Xu#, Lihua Ren#,Jin Zhang, Feng Zhang, Junchao Duan, Xianqing Zhou*, Zhiwei Sun.Endosulfan induces apoptosis by activating the negative regulation pathway ofcell cycle and death receptor pathway in spermatogenic cells. ToxicologyResearch, 2017, 6: 223-231. (5 year IF=2.9500)

48. Jialiu Wei, Lianshuang Zhang, Lihua Ren, Jin Zhang, Jianhui Liu,Junchao Duan, Yang Yu, Yanbo Li, Cheng Peng, Xianqing Zhou*, Zhiwei Sun.Endosulfan induces cell dysfunction through cycle arrest resulting from DNAdamage and DNA damage response signaling pathways. Science of the TotalEnvironment, 2017, 589: 97–106.  (5year IF=10.237)

49. Junchao Duan, Yang Yu, Yang Li, Li Jing, Man Yang, Ji Wang, Yanbo Li,Xianqing Zhou, Mark R. Miller, Zhiwei Sun*. Comprehensiveunderstanding of PM2.5 on gene and microRNA expression patterns in zebrafish(Danio rerio) model. Science of the Total Environment, 2017, 586: 666-674. (5 year IF=10.237)

50. Zhixiong Shi*, Lei Zhang, Yunfeng Zhao, Zhiwei Sun, Xianqing Zhou,Jingguang Li, Yongning Wu. A national survey of tetrabromobisphenol-A,hexabromocyclododecane and decabrominated diphenyl ether in human milk fromChina: Occurrence and exposure assessment. Science of The Total Environment,2017, 599–600: 237-245.  (5 yearIF=10.237)

51. Zhixiong Shi*, Lei Zhang, Zhiwei Sun, Xianqing Zhou, JingguangLi*, Yongning Wu. Dietary exposure assessment of Chinese population totetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenylether: Results of the 5th Chinese Total Diet Study. Environmental Pollution,229: 539-547. (5 year IF=10.3659)

52. Li Jing, Man Yang, Yang Li, Yang Yu, Baolu Liang, Lige Cao, XianqingZhou, Shuangqing Peng*, Zhiwei Sun*. Metallothionein prevents doxorubicincardiac toxicity by indirectly regulating the uncoupling proteins 2. Food andChemical Toxicology, 2017, 110: 204-213. (5 year IF=5.6922)

53. Caixia Guo, Ji Wang, Man Yang, Yang Li, Shuxiang Cui, XianqingZhou, Yanbo Li, Zhiwei Sun. Amorphous silica nanoparticles induce malignanttransformation and tumorigenesis of human lung epithelial cells via P53signaling. Nanotoxicology, 2017, 11(9-10): 1176-1194. (5 year IF=6.3193)

54. Zhixiong Shi*, Lei Zhang, Yunfeng Zhao, Zhiwei Sun, Xianqing Zhou,Jingguang Li*, Yongning Wu. A national survey of tetrabromobisphenol-A, hexabromocyclododecaneand decabrominated diphenyl ether in human milk from China: Occurrence andexposure assessment. Science of the Total Environment, 2017, 599–600: 237–245.  (5 year IF=10.237)