主要从事神经损伤与修复研究，涉及神经损伤与修复的机制、干细胞与组织工程技术修复重症中枢神经损伤与周围神经损伤

国家自然科学基金青年基金 用化学官能团和多肽修饰的透明质酸水凝胶诱导神经干细胞及治疗脑损伤的研究

国家重点研发计划子课题 周围神经损伤后结构和成分变化及生物学紊乱的机制探究

1.        Liang Y, LiS, Li Y, Li M, Sun X, An J, Xu Q, Chen Z, Wang Y*. Impact of hydrogel stiffnesson the induced neural stem cells modulation. Ann Transl Med. 2021 Dec; 9(24):1784.doi: 10.21037/atm-21-6189. PMID: 35071478; PMCID: PMC8756230.

2.        Jiaju Lu, FengyiGuan, Fuzhai Cui, Xiaodan Sun, Lingyun Zhao,Ying Wang,* and XiumeiWang*.Enhanced angiogenesis by the hyaluronic acid hydrogels immobilized with a VEGFmimetic peptide in a traumatic brain injury model in rats. RegenerativeBiomaterials, 2019, Dec;6(6):325-334.  doi: 10.1093/rb/rbz027. Epub2019 Aug 5.

3.        Mo Li, Ying Wang,Jidi Zhang, Zheng Cao, Shuo Wang, Wei Zheng, Qian Li, Tianqi Zheng, XiumeiWang, Qunyuan Xu, Zhiguo Chen*. Culture of pyramidal neural precursors, neuralstem cells, and fibroblasts on various biomaterials. J Biomater Sci Polym Ed.(journal of biomaterials science-polymer edition) 2018 ,29(17):2168-2186.

4.     Shukui Yu, ShenglianYao, Yujun Wen, Ying Wang, Hao Wang, Qunyuan Xu*. Angiogenic microspherespromote neural regeneration and motor function recovery after spinal cord injuryin rats. Scientific Reports, 2016,6:33428

5.     Yujun Wen, ShukuiYu, Yanhong Wu, Rongkai Ju, Hao Wang, Yujun Liu, Ying Wang, and Qunyuan Xu*.Spinal cord injury repair by implantation of structured hyaluronic acid scaffoldwith PLGA microspheres in the rat. Cell Tissue Res,2015.10.1-12.

6.     Rongkai Ju,Yujun Wen, Rongbin Gou, Ying Wang, and Qunyuan Xu*. The Experimental Therapy onBrain Ischemia by Improvement of Local Angiogenesis with Tissue Engineering inThe Mouse. Cell transplantation.2014,23 Suppl1:83-95.

7.        Ying Wang,Shenglian Yao, Qingyuan Meng, Xiaolong Yu, Xiumei Wang, Fuzhai Cui*.Geneexpression profiling and mechanism study of neural stem cells response tosurface chemistry.  RegenerativeBiomaterials.2014,1 (1): 37-47。

8.        Wang Y, WeiY, Zu Z, Ju R, Guo M, Xu Q*, Cui F*. Combination of Hyaluronic Acid Hydrogel Scaffoldand PLGA Microspheres for Supporting Survival of Neural Stem Cells. Pharm Res,2011,28(6): 1406-14.

9.        Liu X, WangY, He J, Wang X, Cui F, Xu Q. Various fates of neuronal progenitor cellobserved on several different chemical functional groups. Front Mater Sci,2011, 5(4): 358-66.

10.    Wang Y, DengH, ZU Z, Shen X, Liang H, Xu Q, Cui F, LEE IS. Interactions between neural stemcells and biomaterials combined with biomolecules. Front Mater Sci, 2010, 4(4):325-31.

11.    Wei Y, He Y,Xu C, Wang Y, Liu B, Wang X, Sun X, Cui FZ, Xu Q. Hyaluronic acid hydrogel modifiedwith nogo-66 receptor antibody and poly-L-lysine to promote axon regrowth afterspinal cord injury. J Biomed Mater Res B Appl Biomater, 2010, 95(1): 110-7.

12.    Ren Y, ZhouZ, Cui F, Wang Y, Zhao J, Xu Q. Hyaluronic acid/polylysine hydrogel as atransfer system for transplantation of neural stem cells. J Bioact CompatPolym, 2009, 24(1): 56-62.