1.主持 国家自然科学基金青年科学基金项目1项（项目号：82001146）；

2.主持 北京市教委科技计划项目一般项目1项（项目号：KM202110025028）；

3.主持 2017年度首都医科大学科研培育基金1项（项目号：PYZ2017061）；

(1)     国家自然科学基金委员会, 青年科学基金项目, 82001146, β-淀粉样蛋白二聚体诱发性阿尔茨海默病恒河猴模型的建立与评价,2021-01-01 至 2023-12-31, 24万元, 主持

(2)     国家自然科学基金委员会, 面上项目, 81971005, Tau种蛋白诱发性阿尔茨海默病猕猴模型的创建,2020-01-01 至 2023-12-31, 55万元, 参与

(3)     北京市教委, 科技计划项目一般项目, KM202110025028, β-淀粉样蛋白低分子寡聚体对阿尔茨海默病神经病变的影响研究,2021-01 至 2023-12, 15万元, 主持

近5年研究成果:

(1)     Xiaoxu Wang*, Lu Dai*, Na Wu, Donghui Wu, Xinyuan Wang, Xia Meng, QileiZhang, Jing Lu, Xiaoxin Yan, Jing Zhang#, Baian Chen#. DEAD-Box Helicase6 Blockade in Brain-Derived Aβ Oligomers From Alzheimer's Disease PatientsAttenuates Neurotoxicity. MedComm. 2025, 6(5):e70156.

(2)     Lu Dai*, Xiaoxu Wang*, Meng Li*, Jiaying Li, Yifei Liu, Na Wu, Xia Meng,Jing Lu, Jing Zhang#, Baian Chen#. Ameliorative effect and underlyingmechanism of the Xiaxue Kaiqiao formula on age-related dementia in Samp8 mice. Phytomedicine.2024,135:155801.

(3)     Jing Zhang*; Na Wu; Shubo Wang; Zitong Yao; FuchuanXiao; Jing Lu; Baian Chen#; Neuronal loss and microgliosis are restricted tothe core of Aβ deposits in mouse models of Alzheimer'sdisease, Aging Cell,2021, 20(6): 13380-13380

(4)     Zhang, Jing*; Chen, Baian*; Lu, Jing; Wu,Yi; Wang, Shubo; Yao, Zitong; Zhu, Liming; Qiao,Yanhua; Sun, Quan; Qin, Wei;Zhao, Qiao; Jia, Jianping; Wei, Cuibai#; Brains of rhesus monkeys display Abeta deposits and glial pathology while lacking A beta dimers and otherAlzheimer's pathologies, Aging Cell, 2019, 18(4): 0-UNSP e12978

(5)    Miaomiao Du*, Yujia Wang*,Xinyuan Wang*, Yifei Liu, Fuchuan Xiao, Jing Zhang, Xia Meng, Kunhe Ma,Na Wu#, Baian Chen#, Jing Lu#. Age-Related Complement C3 Drives MemoryImpairments and Associated Neuropathologies in a Mouse Model. Aging Cell.2025, 20:e70145.

(6)     Na Wu; Fuchuan Xiao; Jing Zhang; Yafei Chi; Yanan Zhai; BaianChen; Jing Lu. Proteomic characteristics of plasma and blood cells in naturalaging rhesus monkeys, Proteomics, 2022, 22(21): 2200049-2200049