首都医科大学附属北京友谊医院风湿科成立于1990年，是市属医院中第一个拥有独立风湿专业和风湿免疫实验室的单位，属国家级住院医师规范化培训基地。友谊医院风湿科从创建至今，秉承“仁、爱、博、精”的院训，经过几代人的努力，逐渐拥有了一支临床经验丰富、精干务实的医疗、教学、科研队伍，科室的诊治水平、医疗质量和医疗服务水平在市属医院中均享有良好的声誉。

       风湿科病房现有编制床位38张，科室年收治病人1300余人次，年门诊量6万余人次。诊治病种包括类风湿关节炎、干燥综合征、系统性红斑狼疮、痛风、骨关节炎、各种脊柱关节炎(如强直性脊柱炎等)、硬皮病、多肌炎/皮肌炎、白塞病、各种系统性血管炎、IgG4相关疾病、成人斯蒂尔病、腹膜后纤维化及复发性多软骨炎等。

       目前科室共有医师14名，其中高级职称5名，博士13名，硕士1名。博士、硕士生导师共3名。该中心成员包括中国女医师协会风湿病分会委员、中华医学会风湿病学分会青委、中国医师协会风湿病分会青委、海峡两岸医药卫生协会IgG4相关性疾病常委兼秘书长、中华医学会内科学分会免疫净化和细胞治疗学组常委兼副秘书长、北京医学会风湿病分会委员等。先后承担科技部国家重点研发计划(子课题)、国家自然科学基金、教育部博士点基金等多项国家级及省部级课题，在《Cell Rep》、《Ann Rheum Dis》、《Rheumatology》等杂志累计发表中英文文章90余篇。主编、参编风湿病专著10余部。

国家自然科学基金（81202343）

国家重点研发计划干细胞及转化研究重点专项（2017YFA0105802）

教育部博士点新教师基金（20120001120047）

首都医学发展科研基金（2022-2-2026）

艾拉莫德 (Grant No. 2022-2-2026)

通州科委：(No.KJ2023CX004)

北京自然科学基金：(Grant No. 7232029)

（1）Zhao, Z., Liu, Y, Bai, M., Zeng, Q., Wang, Z.,Chen, D., Li, Z., & Su, Y. (2023). Clinical profiles differ in IgG4-relateddisease with and without allergy: a large case-control study inChina. Clinical and experimental rheumatology, 41(9), 1808–1814.

（2）Hao Q, Sun M, Liu Y. The spectrum of B cells inthe pathogenesis, diagnosis and therapeutic applications of immunoglobulinG4-related disease. Clin Transl Immunology. 2023;12(12):e1477. 

（3）Bian W, Li Y, Sun F, et al. Immune phenotypechanges in IgG4-related disease: CD161 + Treg and Foxp3 + Treg. Clin Rheumatol.2023;42(4):1113-1124.

（4）Xiao-Ying Zhang, Yu-Xin Zhang, Zi-Qiao Wang, Xin-YuZhang, Xia Zhang, Jia-Yang Jin, Jing Li, Yu-Zhou Gan, Fei Yang, Yan-Min Liu, Yan-YingLiu, Zhan-Guo Li. Study of 43 SLE patients with autoimmune livercirrhosis:emphasis on clinical features anddifferences from lupus without cirrhosis. IntJ Rheum Dis. 2023;26(7):1268-1275. 

（5）Zhou M, Zhang S, Xie X, et al. Diagnostic value of anovel salivary gland ultrasound scoring system in IgG4-related sialadenitis.Rheumatology (Oxford). Published online March 1, 2024.

（6）Zhang T, Lv H, Zhao X, et al. Serum uric acid isassociated with midbrain enlarged perivascular spaces: Results fromMulti-modality Medical imaging sTudy bAsed on KaiLuan Study (META-KLS). ProgNeuropsychopharmacol Biol Psychiatry. 2024;133:111000. 

（7）Wang T, Zhang C, Zhou M, et al. CD8 T cell-derivedperforin regulates macrophage-mediated inflammation in a murine model of gout. ClinRheumatol. 2024;43(6):2027-2034. 

（8）Lv H, Sun J, Zhang T, et al. Associations of serum uricacid variability with neuroimaging metrics and cognitive decline: apopulation-based cohort study. BMC Med. 2024;22(1):256. Published 2024 Jun20.

（9）Zhang T, Liu H, Tian M, et al. Systematic analysis forclinical characteristics and outcomes of IgG4-related disease patients duringthe COVID-19 pandemic. Clin Rheumatol. 2024;43(8):2595-2606.

（10）Zeng W, Zhou H, Wang T, Liu Y. Three cases of IgG4-RDcomplicated by splenic artery aneurysm: a complication of IgG4-RD?. RMDOpen. 2024;10(4):e004554. Published 2024 Nov 9.

（11）Liu Y, Liu S, Liu L, et al. Comparison of the Efficacyand Safety Between GB242 and Infliximab in Patients with Rheumatoid Arthritis:A Phase III Study. Rheumatol Ther. 2022; 9(1): 175–189.

（12）LiuY, Fu J, Ning X, et al.Malignancy Risk of Immunoglobin G4-Related Disease: Evidence from a LargeCohort Multicenter Retrospective Study. Rheumatol Ther. 2021;8(3):1207-1221.

（13） Liu Y, Li C, Wang S, Guo J, etal. Human umbilical cord mesenchymal stem cells confer potent immunosuppressiveeffects in Sjögren's syndrome by inducing regulatory T cells. Mod Rheumatol.2021; 31(1): 186-196. 

（14）Wang K, Wang Z, Zeng Q, et al.Clinical characteristics of IgG4-related retroperitoneal fibrosis versusidiopathic retroperitoneal fibrosis. Plos One. 2021 Feb 18;16(2):e0245601.  (corresponding author) 

（15）Liu Y, Yang F, Chi X, et al.Needle biopsy compared with surgical biopsy: pitfalls of small biopsy inhistologial diagnosis of IgG4-related disease Arthritis Res Ther.  2021;23(1):54.  (corresponding author) 

（16）Liu Y, Zhu L, Wang Z, et al. Clinicalfeatures of IgG4-related retroperitoneal fibrosis among 407 patients withIgG4-related disease: a retrospective study. Rheumatology (Oxford).  2021; 60 (2):767-772.

（17）Liu Y, Xue M, Wang Z, et al. Salivary gland involvement disparities inclinical characteristics of IgG4-related disease: a retrospective study of 428patients. Rheumatology (Oxford), 2020; 59 (3): 634-640. 

（18）Liu Y, Zeng Q, Zhu L, et al. Relapse predictors andserologically unstable condition of IgG4-related disease: a large Chinesecohort. Rheumatology (Oxford). 2020;59(8):2115-2123.

（19）Zeng Q, Liu Y. Commenton: Relapse predictors and serologically unstable condition of IgG4-relateddisease: a large Chinese cohort: reply. Rheumatology (Oxford). 2020 Aug1;59(8):2179-2180. (corresponding author)

（20）Liu YY, Wang SY, Li YN, et al. Activityof fibroblast-like synoviocytes in rheumatoid arthritis was impaired bydickkopf-1 targeting siRNA.Chin Med J (Engl). 2020;133(6):679-686. 

（21）Liu Y, Zhang Y, Bian W, et al.Efficacy and safety of iguratimod on patients with relapsed or refractoryIgG4-related disease. Clin Rheumatol. 2020; 39 (2): 491-497.

（22）参与制定指南： IgG4相关性疾病诊疗规范