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胡晓玲,博士,首都医科大学神经生物学系,副教授。2011年博士毕业于中国科学院神经科学研究所;2011年至2016年在清华大学医学院从事博士后研究工作;2016年入职首都医科大学;2019年至2020年在美国德州西南医学中心访学。主要从事成体神经干细胞起源,成体神经干细胞微环境与大脑损伤修复关系的研究。研究并发现了新的神经干细胞膜表面标志分子及其在神经干细胞发育过程中的重要作用。研究成果发表在Neuron, Nature Neuroscience,Cerebral Cortex, Stem Cell Reports等国际优秀期刊。
2022.01-2025.12 国家自然科学基金面上项目资助 (基金号 82171367)。
2017.01–2019.12 北京市教委科技重点计划资助(基金号:KZ201710025016)。
2013.01–2015.12 国家自然科学基金青年项目资助 (基金号31200798) 。
2021.01-2024.12 国家自然科学基金面上项目资助 (基金号 82171367)。
2017.01–2019.12 北京市教委科技重点计划资助(基金号:KZ201710025016)。
2013.01–2015.12 国家自然科学基金青年项目资助 (基金号31200798) 。
1. Wang DY#, LuoAnfeng#, Bai QR, Gong XL, Zheng Yan, Shen Q*, Hu XL*, Wang XM*. VCAM1Labels a Subpopulation of Neural Stem Cells in the Adult Hippocampus andContributes to Spatial Memory. Stem Cell Reports 2020, 14(6) P1093-1106.(*共同通讯作者)
2. Zhang S, Wang H,Li J, Hu XL*, Qin Shen*. Radial glial cell-derived VCAM1regulates cortical angiogenesis through distinct enrichments in the proximaland distal radial processes. Cerebral Cortex 2020; 30 (6): 3717–3730 (*共同通讯作者)
3. Gao X, Zhang Z,Mashimo T, Shen B, Nyagilo J, Wang H, Wang Y, Liu Z, Mulgaaonkar A, Hu XL,Piccirillo S, Eskiocak U, Dave D, Qin S, Yang Y, Sun X, Fu YX, Zong H, Sun W,Bachoo RM, Ge WP. Gliomas Interact with Non-glioma Brain Cells viaExtracellular Vesicles. Cell Rep. 2020 30, 2489-2500 e2485.
4. Wang H, Xiao Z,Zheng J, Wu J, Hu XL, Yang X, Shen Q. ZEB1 Represses NeuralDifferentiation and Cooperates with CTBP2 to Dynamically Regulate CellMigration during Neocortex Development. Cell Rep. 2019; 27(8):2335-2353.
5. Hu XL,Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, SunX, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q*. Persistent expressionof VCAM1 in radial glial cells is required for the embryonic origin of postnatalneural stem cells. Neuron 2017; 95(2):309–325.IF 16.075
6. Xia Q, Bai QR,Dong M, Sun X, Zhang H, Cui J, Xi H, HuXL*, Shen Q*, Chen L*. Interaction between gastric carcinoma cells and neural cells promotesperineural invasion by a pathway involving VCAM1. Dig.Dis. Sci. 2015; 60(11):3283–3292. (* 共同通讯作者)
7. Hu XL, Wang Y, Shen Q*. Epigenetic control on cell fatechoice in neural stem cells. Protein Cell 2012;3(4):278–290.
8. Tan GH, Liu YY, HuXL, Yin DM, Mei L*, Xiong ZQ*. Neuregulin 1 represseslimbic epileptogenesis through ErbB4 in parvalbumin-expressing interneurons. Nat.Neurosci. 2011;15(2):258–266. IF16.5
9. Hu XL, Cheng XW, Cai L, Tan GH, Xu L, Feng XY, Lu TJ, XiongH, Fei J and Xiong ZQ*. Conditionaldeletion of NRSF in forebrain neurons accelerated epileptogenesis in thekindling model. Cereb. Cortex 2011; 21(9):2158–2165.
10. Hu XL, Cheng X,Fei J, Xiong ZQ*. NRSF is not required for anti-epileptic effect of ketogenicdiet. Epilepsia 2011; 52(9):1609–1616.
11. Zhang X-B, Jiang P, Gong N, Hu XL, Fei D, Xiong ZQ, Xu L,Xu TL*. A-type GABA receptor as a central target of TRPM8 agonist menthol.PLoSONE 2008; 3(10): e3386.
12. Qiu LF, Lu TJ, HuXL, Yi YH, Liao WP and Xiong Z-Q. Limbic epileptogenesis in a mousemodel of fragile X syndrome. Cereb. Cortex 2009;19(7):1504–1514.
13. Chen Q, He S, HuXL, Yu J, Zhou Y, Zheng J, Zhang S, Zhang C, Duan WH, and Xiong ZQ*. Differentialroles of NR2A- and NR2B-containing NMDA receptors in activity-dependentbrain-derived neurotrophic factor gene regulation and limbic epileptogenesis. J.Neurosci. 2007; 27(3):542–552.
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