目前在研课题

1、

题目：miRNA-497-5P/FGF7调控自噬参与晶状体上皮细胞EMT的新机制研究

时间:  2022 /1 /1-2025/12/31

经费：54万

中文：国家自然科学基金， 编号：82171037

英文：The National Natural ScienceFoundation of China，code: 82171037

2、

题目：载SFN智能控释人工晶状体调控TFEB介导的自噬途径抑制后发性白内障的作用及机制研究

时间:  2025 /1 /1-2028/12/31

经费：49万

中文：国家自然科学基金， 编号：82471055

英文：The National Natural Science Foundation of China，code: 82471055

3、

题目：自供电人工晶状体的构建及其电刺激防治后发性白内障的研究，

时间:  2025 /1 /1-2026/12/31

经费：50万

中文：北京市科技新星交叉联合课题， 编号：20240484565

英文：Beijing new-star plan science and technology cross cooperationproject，code: 20240484565

 近5年英文SCI:

1.      Wang Y, Cao K, Guo ZX, Wan XH. Effect of lenscrystallins aggregation on cataract formation. Exp Eye Res. 2025 Feb 13:110288.doi: 10.1016/j.exer.2025.110288. （通讯作者） (SCI IF=3.0)

2.      Tian ZY. Li M. Zhang JS. Mao YY. Guo ZX. Zheng X. Zhao P. Wan XH. Intraocularlens power calculation in cataract patients with keratoconus: Bayesian network meta‑analysis. Int Ophthalmol  2025 Jan 24;45(1):40. doi: 10.1007/s10792-025-03430-8.（通讯作者） (SCI IF=1.4)

3.     Wang JD, Zhang JS, Li XX，WangKJ，Li M, Mao YY, Wan XH*. Knockout of TGF-β receptor II by CRISPR/Cas9delays mesenchymal transition of Lens epithelium and posterior capsuleopacification. Int J Biol Macromol,2024 Feb; 259(Pt 2):129290.doi.10.1016/j.ijbiomac.2024.129290（通讯作者） (SCI IF=8.2)

4.     Wang JD, Liu MR, Chen CX, Cao K, Zhang Y, Zhu XH, WanXH*. Effects ofatropine eyedrops at ten different concentrations for myopia control inchildren: A systematic review on meta-analysis. Eur J Ophthalmol. 2024Feb 20:11206721241229317. doi: 10.1177/11206721241229317.（通讯作者）(SCI IF=2.597)

5.     Zhao HY，Zhang JS，Li M，Chen DJ, Wan XH*. Effect ofcapsular tension ring on the refractive outcomes of patients with extreme highaxial myopia after phacoemulsification. Eur J Med Res 2024 Feb 24;29(1); 142. doi.org/10.1186/s40001-024-01726-6（通讯作者）(SCI IF=4.981)

6.      ZhaoHY, Zhang JS, Li M, Chen DJ, Yang X, Wan XH*. Tilt and decentration of the crystalline lens in ultra-high myopia withcataract and its influencing factors: A study based on CASIA2'. EurJ Ophthalmol. 2024 Aug 2:11206721241267028. doi:10.1177/11206721241267028. （通讯作者）(SCI IF=2.597)

7.     Zhang JS, Li J, Wang JD, Xiong Y, Cao K, Li M, Wang KJ, Mao YY, Liu JY, WanXH*. The Association of Myopia Progression with Changes in Retinal Thicknessamong Primary School Students with Myopia. J Opthalmol. 2024August 06.doi.org/10.1155/2024/1055700（通讯作者）(SCI IF=1.7）

8.      Li M, Wang JD, Zhang JS, Mao YY, Cao K, WanXH*. Comparison of the accuracy of threeintraocular lens power calculation formulas in cataract patients with priorradial keratotomy. Eur J MedRes.2023 Jan 11;28(1):20. doi.org/10.1186/s40001-023-00998-8（通讯作者）(SCI IF=4.981)

9.      Wang KJ, Wang JX, Wang JD, Li M, Zhang JS, Mao YY, Wan XH*. Congenital coralliform cataract is thepredominant consequence of a recurrent mutation in the CRYGD gene. Orphanet J Rare Dis. 2023 Jul 21;18(1):200.doi: 10.1186/s13023-023-02816-0. （通讯作者）(SCI IF=4.303)

10.    Li J*, Zhang F, Bian W, Chen YY, Liu JY,Liu ZY, Xiong Y, Wan XH*. cGASinhibition alleviates Alu RNA-induced immune responses and cytotoxicity inretinal pigmented epithelium. Cell Biosci. 2022 Jul 25;12(1):116.doi: 10.1186/s13578-022-00854-y. （共同通讯作者）(SCI IF=9.584)

11.    Wang JD,Zhang JS, Li M, Mao YY, Yusufu M, Wan XH. Comparison of diferent pupil dilatation methods for phacoemulsifcationin eyes with a small pupil.  BMCOphthalmol. 2022 Apr 18;22(1):173. doi.org/10.1186/s12886-022-02402-1（通讯作者）(SCIIF=2.086)

12.   Zhang JS, Li J, Wang JD，Xiong Y , Cao k, Hou SM, Yusufu M, Wang KJ, Li M, Mao YY, Sun XL, Chen SY, Liu ZY, Jin ZB, Wang NL, Wan XH.The association of myopia progression with the morphological changes ofoptic disc and β-peripapillary atrophy in primary school students. GraefesArch Clin Exp Ophthalmol. 2022 Feb;260(2):677-687. doi: 10.1007/s00417-021-05331-9. （通讯作者）(SCI IF=3.535)

13.   Mao YY，Li M，Wang JD，Wang KJ，Zhang JS，Chen SY，Liu X，Liang QF，Gao F，Wan XH.NIR-triggered drug delivery system for chemo-photothermal therapy ofposterior capsule opacification. J Control Release.2021 Nov 339（10）：391-402.doi:10.1016/j.jconrel.2021.09.030（通讯作者）(SCI IF=11.467)

14.    Mao YY, Yu SR,Kang YY, Zhang DD, Wu S, Zhang JX, Xiong Y, Li M, Zhang JS, Wang JD, Wang KJ,Wan XH. CuInS/ZnS quantum dots modified intraocular lens forphotothermal therapy of posterior capsule opacification. ExpEye Res. 2021, Jan;202:108282. Doi:10.1016/j.exer.2020.108282. （通讯作者） (SCI  IF=3.770)

15.    Zhang JS , Wang JD,Yusufu M, Cao K, Jin SS, Xiong Y, Li J, Sun XL, Chen SY, Liu ZY, Fu J, Li L,You QS, Wan XH. Theeffect of retaining intact posterior capsule in congenital cataract surgery inchildren aged 4–8 years. BMC Ophthalmol.2021 Sep 11;21(1):332.doi:10.1186/s12886-021-02098-9（通讯作者）(SCI IF=2.086)

16.   Cao K, Zhang JS, Wang JD, Yusufu M, Jin SS, Chen SY, Wang NL, JinZB, Wan XH. Implantable collamer lens versus small incision lenticule extraction for highmyopia correction: A systematic review and metaanalysis. BMC Ophthalmol; 2021, Dec 27;21(1):450.doi.org/10.1186/s12886-021-02206-9 （通讯作者）(SCI IF=2.086)

17.    Chen CX, Wang JD, Zhang JS, Xiong Y, Li J, Chen SY, Sun XL, Liu ZY,Mayinuer Y, Wan XH. Effect of Lens Capsular Tension Ring onPreventing Capsular Contraction Syndrome in the Surgery of Retinitis PigmentosaCombined with Cataract: Retrospective Case Series. Int J Clin Pract.2021 Apr 28:e14272. doi: 10.1111/ijcp.14272. （通讯作者）（SCI  IF=3.149）

18.    Jin SS, Zhang JS, Wang JD, Yusufu M,Cao K, Zhu GY, He HL, Wan XH. Advisability of primaryintraocular lens implantation for infants under 2: A systematic review andmeta-analysis. Int J Clin Pract. 2021 Mar 16:e14143. doi:10.1111/ijcp.14143.（通讯作者）（SCI IF=3.149）

19.    Li M, Zhang XF, Yusufu M, Liu L, Wang S, Wang JD,Zhang JS, Wang KJ, Mao YY, Cao K, Chen SY, Yao QN, Li JJ*, Wan XH*. Prevalence and clinical characteristics ofmyelinated retinal nerve fibres in a Chinese teleophthalmology system. Curr Eye Res. 2021,46(9): 1406-1413.Doi:10.1080/02713683.2021.1887273.（共同通讯作者）（SCI  IF=2.555）

20.    Wang KJ, Liao XY, Lin KX, Xi YB, Wang S, Wan XH*,Yan BY*. Anovel F30S mutation in γS-crystallin causes autosomal dominant congenitalnuclear cataract by increasing susceptibility to stresses, Int J Biol Macromol,2021 Mar 1; 172:475-482.doi:10.1016/j.ijbiomac.2021.01.079 （共同通讯作者） (SCI  IF=8.025)

21.    Zhang JS, Wang JD,Zhu GY, Yusufu M, Xiong Y, Li J, Cao K, Jin SS, He HL, Sun XL, Wan XH.The high expression of the pain-related inflammatory factors in the eyes ofcataract patients infected with hepatitis B virus. Cytokine. 2020 October; 134:155189.https://doi.org/10.1016/j.cyto.2020.155189. （通讯作者） (SCI IF=3.926)

22.    Zhang JS, Wang JD,Zhu GY, Li J, Xiong Y, Yusufu M, He HL, Sun XL, MaTJ, Tao Y, He SZ*, WanXH*. The expression of cytokines in aqueous humor of high myopicpatients with cataracts. Mol Vis.2020 Mar 5;26:150-157. http://www.molvis.org/molvis/v26/150/（共同通讯作者）(SCI IF=2.711)

23.    WangJD, Zhang JS, Xiong Y, Li J, Li XX, Zhao J, Zhu GY, He HL, Yusufu M, WanXH.  TGF-β-β Regulation ofMicroRNA miR-497-5p and Ocular Lens Epithelial Cell Proliferation andMesenchymal-Transition. Sci ChinaLife Sci. 2020. 63,https://doi: 10.1007/s11427-019-1603-y（通讯作者） (SCI  IF=10.372)

24.    Wang JD, Liu X,Zhang JS, Xiong Y, Li J, Li XX, Zhao J, You QS, Huang Y,  Espina M,JhanjiV，Wan XH. Effects and risks of 3.2-mm transparent corneal incisionphacoemulsification for cataract after radial keratotomy. J Int Med Res. 2020.March 27,https://doi.org/10.1177/0300060519895679（通讯作者）(SCI IF=1.573)

25.    Cao K, Wang JD,Zhang JS, Yusufu M, Jin S, Zhu GY, He HL, Qi Y, Wan XH. The effectiveness and safety of posterior scleralreinforcement with vitrectomy for myopic foveoschisis treatment: a systematicreview and meta-analysis[J]. GraefesArch Clin Exp Ophthalmol, 2020,258(2):257-271. doi:10.1007/s00417-019-04550-5.（通讯作者）(SCIIF=3.535)

26.   Cao K, Wan XH. Authors'response to: Methodological challenges with randomized clinical trials formultifocal intraocular lenses (MFIOLs). SurvOphthalmol. 2020 May - Jun;65(3):392-394. doi:10.1016/j.survophthal.2019.10.006. Epub 2019 Nov 6.（通讯作者）(SCI IF=6.197)

万修华专著（主编/副主编）：

1、万修华，陶芳标。《新型冠状病毒肺炎眼科防护手册》。主编，北京，人民卫生出版社，2020.3. 标准书号： ISBN  978-7-117-29834-6

2、王宁利，万修华，等。《同仁眼科手术基础教程》。副主编，北京，人民卫生出版社，2017.1. 标准书号：ISBN  978-7-117-23228-9/R•23229