张星虎教授团队在神经免疫性疾病，如多发性硬化、脱髓鞘病、重症肌无力、格林巴利综合征及其他与自身免疫相关的神经系统疾病，以及神经感染性疾病，如病毒性脑炎、结核性脑膜炎、真菌性脑膜炎、脑脓肿、化脓性脑膜炎、脑囊虫病等方面，有丰富的诊断及治疗经验。

1.   Liu J, Zhou R, Gong Y, Ding X, Huang Q,Zhang Y, Feng Y, Wang D, Zhou H, Ma Y, Zhang X, Zhou Y. A prospective study ontryptophan immunoadsorption in AQP4 antibody-positive neuromyelitis opticaspectrum disorders. J Clin Apher. 2022 Feb 1.Onlineahead of print.

2.   Ma J, Yu H, Wang H, Zhang X, Feng K.Evaluation of effect of empirical attack-preventive immunotherapies inneuromyelitis optica spectrum disorders: An update systematic review and meta-analysis. J Neuroimmunol. 2022 Feb 15;363:577790.

3.   Wang Y, Ma J, Chang H, Zhang X, Yin L.Efficacy of mycophenolate mofetil in the treatment of neuromyelitis opticaspectrum disorders: An update systematic review and meta -analysis. MultScler Relat Disord. 2021 Oct;55:103181.

4.   Cong H, Liang M, Wang Y, Chang H, Du L,Zhang X, Yin L. Icariin ameliorates the cuprizone-induced acute brain demyelinationand modulates the number of oligodendrocytes, microglia and astrocytes in thebrain of C57BL/6J mice. Brain Res Bull. 2021 Oct;175:37-47.

5.   Zhuo Z, Duan Y, Tian D, Wang X, Gao C,Ding J, Zheng F, Zhang T, Zhang X, Barkhof F, Shi FD, Liu Y. Brain structuraland functional alterations in MOG antibody disease. Mult Scler. 2021Aug;27(9):1350-1363.

6.   Zheng F, Li Y, Zhuo Z, Duan Y, Cao G,Tian D, Zhang X, Li K, Zhou F, Huang M, Li H, Li Y, Zeng C, Zhang N, Sun J, YuC, Han X, Hallar S, Barkhof F, Liu Y. Structural and functional hippocampalalterations in Multiple sclerosis and neuromyelitis optica spectrum disorder. MultScler. 2021 Aug 11:13524585211032800.

7.   Du L, Chang H, Xu W, Zhang X, Yin L.Elevated chemokines and cytokines for eosinophils in neuromyelitis opticaspectrum disorders. Mult Scler Relat Disord. 2021 Jul;52:102940.

8.   Duan Y, Zhuo Z, Li H, Tian DC, Li Y,Yang L, Gao C, Zhang T, Zhang X, Shi FD, Barkhof F, Liu Y. Brain structuralalterations in MOG antibody diseases: a comparative study with AQP4seropositive NMOSD and MS. J Neurol Neurosurg Psychiatry. 2021Jul;92(7):709-716.

9.   Chang H, Cong H, Wang H, Du L, Tian DC,Ma Y, Xu Y, Wang Y, Yin L, Zhang X. Thymic Involution and Altered Naive CD4 TCell Homeostasis in Neuromyelitis Optica Spectrum Disorder. Front Immunol.2021 Jul 16;12:645277.

10. Gao C, Zhuo Z, Duan Y, Yao Y, Su L,Zhang X, Song T. Structural and Functional Alterations in Visual Pathway AfterOptic Neuritis in MOG Antibody Disease: A Comparative Study With AQP4Seropositive NMOSD. Front Neurol. 2021 Jun 9;12:673472.

11. Wang Y, Chang H, Zhang X, Yin L.Efficacy of rituximab in the treatment of neuromyelitis optica spectrumdisorders: An update systematic review and meta-analysis. Mult Scler RelatDisord. 2021 May;50:102843.

12. Zhuo Z, Li Y, Duan Y, Cao G, Zheng F,Ding J, Tian D, Wang X, Wang J, Zhang X, Li K, Zhou F, Huang M, Li Y, Li H,Zeng C, Zhang N, Sun J, Yu C, Han X, Haller S, Barkhof F, Shi F, Liu Y.Subtyping relapsing-remitting multiple sclerosis using structural MRI. JNeurol. 2021 May;268(5):1808-1817.

13. Xu Y, Ren Y, Li X, Xu W, Wang X, Duan Y, Liu Y, Zhang X, Tian DC. PersistentlyGadolinium-Enhancing Lesion Is a Predictor of Poor Prognosis in NMOSD Attack: aClinical Trial. Neurotherapeutics. 2021 Apr;18(2):868-877.

14. Zhou R, Zeng Q, Yang H, Xu Y, Tan G,Liu H, Wang L, Zhou H, Zhang M, Feng J, Jin T, Zhang X, Wang J, Zhang X, Gao F,Yang C, Bu B, Li C, Zhang M, Dong H, Lin A, Liu W, Wu L, Wang M, Tang Y, WangH, Long Y, Wang Z, Zheng W. Status of Immunotherapy Acceptance in ChinesePatients With Multiple Sclerosis: Analysis of Multiple Sclerosis PatientSurvival Report 2018. Front Neurol. 2021 Apr 8;12:651511.

15. Cong H, Zhang M, Chang H, Du L, ZhangX, Yin L. Icariin ameliorates the progression of experimental autoimmuneencephalomyelitis by down-regulating the major inflammatory signal pathways ina mouse relapse-remission model of multiple sclerosis. Eur J Pharmacol.2020 Oct 15;885:173523.

16. Li W, Wu W, Chang H, Jiang M, Gao J, XuY, Xu D, Yin L, Zhang X. Cerebrospinal Fluid Cytokines in Patients withNeurosyphilis: The Significance of Interleukin-10 for the Disease. BiomedRes Int. 2020 Oct 1;2020:3812671.

17. Du L, Chang H, Xu W, Wei Y, Wang Y, YinL, Zhang X. Effect of NMO-IgG on the interleukin-6 cascade in astrocytes viaactivation of the JAK/STAT3 signaling pathway. Life Sci. 2020 Oct1;258:118217.

18. Song T, Chang H, Du L, Yin L, Shi F,Zhang X. Glucocorticoid receptor mutations and clinical sensitivity toglucocorticoid in Chinese multiple sclerosis patients. Neurol Sci. 2020Oct;41(10):2767-2771.

19. Li X, Tian DC, Fan M, Xiu Y, Wang X, LiT, Jia D, Xu W, Song T, Shi FD, Zhang X. Intravenous immunoglobulin for acuteattacks in neuromyelitis optica spectrum disorders (NMOSD). Mult Scler RelatDisord. 2020 Sep;44:102325.

20. Tian DC, Xiu Y, Wang X, Shi K, Fan M,Li T, Li H, Su L, Ma Y, Xu W, Song T, Liu Y, Shi FD, Zhang X. Cortical Thinningand Ventricle Enlargement in Neuromyelitis Optica Spectrum Disorders. FrontNeurol. 2020 Aug 27;11:872.

21. Peng Y, Dai F, Liu L, Chen W, Yan H,Liu A, Zhang X, Wang X, He J, Li Y, Li C, Chen L, Zhao Y, Li L, Ma Q, Wang J.Validation of the NEOS score in Chinese patients with anti-NMDAR encephalitis. NeurolNeuroimmunol Neuroinflamm. 2020 Aug 5;7(5):e860.

22. Du L, Wang H, Zhou H, Chang H, Wei Y,Cong H, Xu W, Ma Y, Song T, Zhang X, Yin L. Anti-NMDA receptor encephalitisconcomitant with myelin oligodendrocyte glycoprotein antibody diseases: Aretrospective observational study. Medicine (Baltimore). 2020 Jul31;99(31):e21238.

23. Fan M, Qiu W, Bu B, Xu Y, Yang H, HuangD, Lau AY, Guo J, Zhang MN, Zhang X, Yang CS,  Chen J, Zheng P, Liu Q, Zhang C, Shi FD. Riskof COVID-19 infection in MS and neuromyelitis optica spectrum disorders. NeurolNeuroimmunol Neuroinflamm. 2020 Jun 4;7(5):e787.

24. Zhang C, Zhang M, Qiu W, Ma H, Zhang X,Zhu Z, Yang CS, Jia D, Zhang TX, Yuan M, Feng Y, Yang L, Lu W, Yu C, BennettJL, Shi FD; TANGO Study Investigators.Safety and efficacy of tocilizumab versusazathioprine in highly relapsing neuromyelitis optica spectrum disorder(TANGO): an open-label, multicentre,randomised, phase 2 trial. Lancet Neurol.2020 May;19(5):391-401.

25. Du L, Chang H, Wei Y, Zhang X, Yin L.Different roles of soluble CD40 ligand in central nervous system damage. NeurolRes. 2020 May;42(5):372-378.

26. Li W, Chang H, Wu W, Xu D, Jiang M, GaoJ, Huang Y, Xu Y, Yin L, Zhang X.Increased CSF Soluble TREM2 Concentration inPatients With Neurosyphilis. Front Neurol. 2020 Feb 5;11:62.

27. Wei Y, Chang H, Feng H, Li X, Zhang X,Yin L. Low Serum Interleukin-10 Is an Independent Predictive Factor for theRisk of Second Event in Clinically Isolated Syndromes. Front Neurol.2019 Jun 11;10:604.

28. Xu W, Zhou H, Li X, Wang L, Guo X, YinL, Chang H, Wei Y, Li Q, Deng J, Zhou X, Yang H, Zhang X, Yi F, Ma W.C1Q/TNF-related protein 4 expression correlates with herpes simplexencephalitis progression. Ann Transl Med. 2019 Jun;7(11):235.

29. Chang H, Wei Y, Chen Y, Du L, Cong H,Zhang X, Geng X, Yin L. The antipsychotic-like effects of clozapine in C57BL/6mice exposed to cuprizone:Decreased glial activation. Behav Brain Res.2019 May 17;364:157-161.

30. Li W, Jiang M, Xu D, Kou C, Zhang L,Gao J, Qin K, Wu W, Zhang X. Clinical and Laboratory Characteristics ofSymptomatic and Asymptomatic Neurosyphilis in HIV-Negative Patients: ARetrospective Study of 264 Cases. Biomed Res Int. 2019 May6;2019:2426313.

31. Song T, Li X, Liu Y, Zhang X.Prevalence and risk factors of deep venous thrombosis in patients withlongitudinally extensive transverse myelitis: one center data from China. BMCNeurol. 2018 Oct 30;18(1):179.

32. Wei Y, Chang H, Li X, Du L, Xu W, CongH, Yao Y, Zhang X, Yin L. CSF-S100B Is a Potential Candidate Biomarker forNeuromyelitis Optica Spectrum Disorders.Biomed Res Int. 2018 Oct 22;2018:5381239.

33. Gong X, Mei S, Li X, Li X, Zhou H, LiuY, Zhou A, Yang L, Zhao Z, Zhang X. Association between TPMT*3C and decreasedthiopurine S-methyltransferase activity in patients with neuromyelitis opticaspectrum disorders in China. Int J Neurosci. 2018 Jun;128(6):549-553.

34. Wei Y, Chang H, Li X, Wang H, Du L,Zhou H, Xu W, Ma Y, Yin L, Zhang X. Cytokines and Tissue Damage Biomarkers inFirst-Onset Neuromyelitis Optica Spectrum Disorders: Significance ofInterleukin-6. Neuroimmunomodulation. 2018;25(4):215-224.

35. Mei S, Li X, Gong X, Zhang X, Li X,Yang L, Zhu L, Zhou H, Liu Y, Zhou A, Zhang X, Zhao Z. Comparison of6-mercaptopurine with 6-thioguanine for the analysis of thiopurineS-methyltransferase activity in human erythrocyte by LC-MS/MS. BiomedChromatogr. 2017 Sep;31(9).

36. Li X, Mei S, Gong X, Zhou H, Yang L,Zhou A, Liu Y, Li X, Zhao Z, Zhang X. Relationship between Azathioprinemetabolites and therapeutic efficacy in Chinese patients with neuromyelitisoptica spectrum disorders. BMC Neurol. 2017 Jul 5;17(1):130.