附属北京世纪坛医院-石汉平导师介绍
石汉平
教授
硕，博士生导师
男
附属北京世纪坛医院
肿瘤学
肿瘤综合治疗(含肿瘤代谢与营养）
shihp@vip.163.com
石汉平，医学博士，教授，主任医师，博士生导师，美国外科学院院士（FACS），首都医科大学附属北京世纪坛医院胃肠外科主任，临床营养科主任，国家市场监管重点实验室（肿瘤特医食品）主任，肿瘤代谢与营养北京国际科技合作基地主任，国家重点研发计划项目首席科学家，首都医科大学“特殊人才引进”教授，《肿瘤代谢与营养电子杂志》《Journal of Nutritional Oncology》《Precision Nutrition》杂志创刊主编。发表专业论文570篇，主编专著29部，以第一作者获省部级科技进步一等奖3项。先后获“全国优秀科技工作者”、“科学中国人“、“全国优秀科普工作者”、“健康中国（2019年度）十大人物”、“外科学、肿瘤营养学全国首席科学传播专家”荣誉称号及“敬祐生命、荣耀医者：肿瘤专科精英及科普影响力奖”。2021年成为全球营养学领域最活跃的5位学者，位列第二，为首次进入前5位的亚洲学者。
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科研项目
1.中国科学技术协会--2016承接政府转移职能与科技公共服务工程（2016.04-2016.12，项目编号2016GGFZ001）全国规范化肿瘤营养示范病房
2.国家卫计委--食品安全国家标准（2016.11.24-2017.10.31,项目编号spaq-2016-119）肿瘤全营养配方食品
3.国家自然科学基金项目（2017.01-2019.12，项目编号81672888）LncRNA-421627增强mTORC1-HIF1代谢重编程促进结肠癌转移
4.国家重点研发计划项目（2017.07-2021.06，项目编号2017YFC1309200，800万）恶性肿瘤姑息治疗和护理关键技术研究
5.北京市科学技术委员会（2018.01-2021.12，项目编号SCW2018-06，335万）北京社区及医疗机构老年人群健康状态综合评估量表的研发、评估及应用研究
6.首都医科大学临床医学高精尖学科建设项目----首都医科大学与北京协和医学院共建项目（2019.01-2021.12，项目编号1192070317，经费30万）癌性肠梗阻
7.肿瘤代谢与营养北京市国际科技合作基地（BeijingInternational Science and Technology Cooperation Base for CancerMetabolism and Nutrition）。北京市科学技术委员会，2018年
8. 特殊医学用途肿瘤全营养配方食品技术审评规程研究。国家市场监督管理总局。2020年7月1日至2020年12月31日，10万
9. 首都医科大学2020临床医学高精尖学科共建项目（2020.10-2021.03，项目编号1202100313，金额7万）癌性肠梗阻的临床治疗及应用
10.国家重点研发计划项目（2022.5-2025.5,项目编号2022YFC2009600，金额1982万）临床实验室检验新技术与参考系统建立应用研究
队列研究
1.常见恶性肿瘤营养状况与临床结局相关性研究（Investigation on Nutrition Status and itsClinical Outcome of Common Cancers，INSCOC，ChiCTR180002032）
2.生活方式医学干预改善肿瘤患者结局研究（Personalized lifestyle Medicine to Improve Outcome for Patient with Cancer，LIOC，ChiCTR2100044548）
3.中国精准营养与健康KAP真实世界研究（China Precision Nutrition and Health- KAP Real World Study，CPN-KAPS，ChiCTR2100051983）
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研究成果
1. Xie H, Ruan G, Ge Y, Zhang Q,Zhang H, Lin S, Song M, Zhang X, Liu X, Li X, Zhang K, Yang M, Tang M, Song CH,Shi H. Inflammatory burden as a prognostic biomarker for cancer. ClinNutr. 2022 Jun;41(6):1236-1243. (IF: 7.324)
2. Liu T, Zhang Q, Song C, SiyinST, Chen S, Zhang Q, Song M, Cao L, Shi H. C-reactive proteintrajectories and the risk of all cancer types: A prospective cohort study. IntJ Cancer. 2022 Jul 15;151(2):297-307. (IF: 7.396)
3. Xie H, Ruan G, Deng L, Zhang H,Ge Y, Zhang Q, Lin S, Song M, Zhang X, Liu X, Li X, Zhang K, Yang M, Tang M, HuW, Weng M, Shi H. Comparison of absolute and relative handgrip strengthto predict cancer prognosis: A prospective multicenter cohort study. Clin Nutr.2022 Aug;41(8):1636-1643. (IF: 7.324)
4. Fu Z, Zhang R, Wang KH, CongMH, Li T, Weng M, Guo ZQ, Li ZN, Li ZP, Wang C, Xu HX, Song CH, Zhuang CL,Zhang Q, Li W, Shi HP; INSCOC Study Group. Development and validation ofa Modified Patient-Generated Subjective Global Assessment as a nutritionalassessment tool in cancer patients. J Cachexia Sarcopenia Muscle. 2022Feb;13(1):343-354. (IF: 12.910)
5. Song M, Zhang Q, Song C, Liu T,Zhang X, Ruan G, Tang M, Xie H, Zhang H, Ge Y, Li X, Zhang K, Yang M, Li Q, LiuX, Lin S, Xu Y, Xu H, Wang K, Li W, Shi H. The advanced lung cancerinflammation index is the optimal inflammatory biomarker of overall survival inpatients with lung cancer. J Cachexia Sarcopenia Muscle. 2022 Jul 14. (IF: 12.910)
6. Ruan GT, Xie HL, Zhu LC, Ge YZ,Yan L, Liao C, Gong YZ, Shi HP. Immune ULBP1 is Elevated in ColonAdenocarcinoma and Predicts Prognosis. Front Genet. 2022 Feb 8;13:762514. (IF:4.599)
7. Liu YY, Ruan GT, Ge YZ, Li QQ,Zhang Q, Zhang X, Tang M, Song MM, Zhang XW, Li XR, Zhang KP, Yang M, Hu CL,Liu T, Xie HL, Liu XY, Lin SQ, Weng M, Yao QH, Wang ZP, Cong MH, Shi HP.Systemic inflammation with sarcopenia predicts survival in patients withgastric cancer. J Cancer Res Clin Oncol. 2022 Apr 18. (IF: 4.553)
8. Liu T, Fan Y, Zhang Q, Wang Y,Yao N, Song M, Zhang Q, Cao L, Song C, Shi H. The combination ofmetabolic syndrome and inflammation increased the risk of colorectal cancer.Inflamm Res. 2022 Aug;71(7-8):899-909. (IF: 4.575)
9. Yang M, Zhang Q, Ge Y, Tang M,Hu C, Wang Z, Zhang X, Song M, Ruan G, Zhang X, Liu T, Xie H, Zhang H, Zhang K,Li Q, Li X, Liu X, Lin S, Shi H. Prognostic Roles of Inflammation- andNutrition-Based Indicators for Female Patients with Cancer. J Inflamm Res. 2022Jun 17;15:3573-3586. (IF: 6.922)
10. Song M, Li Y, Chen Z, Zhang J,Yang L, Zhang F, Song C, Miao M, Chang W, Shi H. The Long Non-Coding RNAFAM222A-AS1 Negatively Modulates MiR-Let-7f to Promote Colorectal CancerProgression. Front Oncol. 2022 May 12;12:764621. (IF: 6.244)
11. Cong M, Song C, Xu H, Song C,Wang C, Fu Z, Ba Y, Wu J, Xie C, Chen G, Chen Z, Zhou L, Li T, Deng L, Xin L,Yang L, Cui J, Shi H; Investigation on Nutrition Status and ClinicalOutcome of Common Cancers (INSCOC) Group. The patient-generated subjectiveglobal assessment is a promising screening tool for cancer cachexia. BMJSupport Palliat Care. 2022 May;12(e1):e39-e46. (IF: 3.568)
12. Ruan GT, Xie HL, Zhang HY, LiuCA, Ge YZ, Zhang Q, Wang ZW, Zhang X, Tang M, Song MM, Zhang XW, Yang M, ChenYB, Yu KY, Deng L, Gong YZ, Hu W, Wang KH, Cong MH, Shi HP. A NovelInflammation and Insulin Resistance Related Indicator to Predict the Survival ofPatients With Cancer. Front Endocrinol (Lausanne). 2022 Jun 20;13:905266. (IF:5.555)
13. Ruan GT, Xie HL, Deng L, Ge YZ,Zhang Q, Wang ZW, Zhang X, Zhang HY, Tang M, Song MM, Zhang XW, Yang M, Pan L,Wang KH, Cong MH, Gong YZ, Wang MY, Shi HP. A Novel SystemicInflammation Prognostic Score to Stratify Survival in Elderly Patients WithCancer. Front Nutr. 2022 Jul 5;9:893753. doi: 10.3389/fnut.2022.893753. PMID:35866083; PMCID: PMC9294408. (IF: 6.576)
14. Ruan X, Wang X, Zhang Q,Nakyeyune R, Shao Y, Shen Y, Niu C, Zhu L, Zang Z, Wei T, Zhang X, Ruan G, SongM, Miles T, Liu F, Shi H; Investigation on Nutrition Status and ClinicalOutcome of Common Cancers (INSCOC) Group. The performance of three nutritionaltools varied in colorectal cancer patients: a retrospective analysis. J ClinEpidemiol. 2022 May 7;149:12-22. (IF: 6.437)
15. Zhang X, Li X, Shi H, Zhang K,Zhang Q, Tang M, Li W, Zhou F, Liu M, Cong M, Shi H. Association of thefat-free mass index with mortality in patients with cancer: A multicenterobservational study. Nutrition. 2022 Feb;94:111508. (IF: 4.008)
16. Zhang XW, Zhang Q, Song MM,Zhang KP, Zhang X, Ruan GT, Yang M, Ge YZ, Tang M, Li XR, Wang KH, Shi HP.The prognostic effect of hemoglobin on patients with cancer cachexia: amulticenter retrospective cohort study. Support Care Cancer. 2022Jan;30(1):875-885. (IF: 3.603)
17. Liu CA, Zhang Q, Ruan GT, ShenLY, Xie HL, Liu T, Tang M, Zhang X, Yang M, Hu CL, Zhang KP, Liu XY, Shi HP.Novel Diagnostic and Prognostic Tools for Lung Cancer Cachexia: Based onNutritional and Inflammatory Status. Front Oncol. 2022 Jul 11;12:890745. (IF:6.244)
18. Ruan GT, Xie HL, Gong YZ, GeYZ, Zhang Q, Wang ZW, Zhang X, Zhang HY, Tang M, Song MM, Zhang XW, Yang M,Chen YB, Yu KY, Deng L, Wang KH, Cong MH, Shi HP. Prognostic importanceof systemic inflammation and insulin resistance in patients with cancer: aprospective multicenter study. BMC Cancer. 2022 Jun 25;22(1):700. (IF: 4.430)
19. Ruan GT, Ge YZ, Xie HL, Hu CL,Zhang Q, Zhang X, Tang M, Song MM, Zhang XW, Liu T, Li XR, Zhang KP, Yang M, LiQQ, Chen YB, Yu KY, Braga M, Cong MH, Wang KH, Barazzoni R, Shi HP.Association Between Systemic Inflammation and Malnutrition With Survival inPatients With Cancer Sarcopenia-A Prospective Multicenter Study. Front Nutr.2022 Feb 7;8:811288. (IF: 6.576)
20. Zhang X, Zhang Q, Tang M, ZhangKP, Zhang XW, Song MM, Ruan GT, Sun Q, Li W, Xu HX, Cong MH, Deng L, Shi HP.Nutrition-inflammation marker enhances prognostic value to ECOG performancestatus in overweight or obese patients with cancer. JPEN J Parenter EnteralNutr. 2022 May 19. (IF: 4.016)
21. Liu T, Song C, Zhang Y, SiyinST, Zhang Q, Song M, Cao L, Shi H. Hepatitis B virus infection and therisk of gastrointestinal cancers among Chinese population: A prospective cohortstudy. Int J Cancer. 2022 Mar 15;150(6):1018-1028. (IF: 7.396)
22. Ge YZ, Ruan GT, Zhang Q, DongWJ, Zhang X, Song MM, Zhang XW, Li XR, Zhang KP, Tang M, Li W, Shen X, ShiHP; Investigation on the Nutrition Status and Clinical Outcome of CommonCancers (INSCOC) Group. Extracellular water to total body water ratio predictssurvival in cancer patients with sarcopenia: a multi-center cohort study. NutrMetab (Lond). 2022 May 7;19(1):34. (IF: 4.169)
23. Yang M, Zhang Q, Ge YZ, Tang M,Hu CL, Wang ZW, Zhang X, Song MM, Ruan GT, Zhang XW, Liu T, Xie HL, Zhang HY,Zhang KP, Li QQ, Li XR, Liu XY, Lin SQ, Shi HP. Prognostic Roles ofGlucose to Lymphocyte Ratio and Modified Glasgow Prognosis Score in PatientsWith Non-small Cell Lung Cancer. Front Nutr. 2022 May 10;9:871301. (IF: 6.576)
24. Li XR, Zhang Q, Zhang KP, ZhangX, Ruan GT, Song MM, Ge YZ, Zhang XW, Song CH, Shi HP. Association ofserum total bilirubin with survival outcomes in patients with cancer cachexia:A prospective, multicenter cohort study. Nutrition. 2022 Apr 30;102:111711. (IF:4.008)
25. Xie H, Ruan G, Zhang H, ZhangQ, Ge Y, Song M, Zhang X, Lin S, Liu X, Liu Y, Zhang X, Li X, Zhang K, Yang M,Tang M, Li Z, Shi H. Association of Modified Geriatric Nutrition RiskIndex and Handgrip Strength With Survival in Cancer: A Multi-Centre CohortStudy. Front Nutr. 2022 Apr 1;9:850138. (IF: 6.576)
26. Xie H, Ruan G, Zhang Q, Ge Y,Song M, Zhang X, Liu X, Lin S, Zhang X, Li X, Zhang K, Yang M, Tang M, Cong M,Shi H. Combination of Nutritional Risk Index and Handgrip Strength on theSurvival of Patients with Cancer Cachexia: A Multi- Center Cohort Study. JInflamm Res. 2022 Feb 15;15:1005-1015. (IF: 6.922)
27. Zhuang CL, Zhang FM, Xu HX,Weng M, Yao Y, Zhou FX, Li ZN, Guo ZQ, Li T, Li W, Shi HP; Investigationon Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) Group.Reference values of low body mass index, mid-upper arm circumference, and calfcircumference in cancer patients: A nationwide multicenter observational study.Nutrition. 2022 Jul-Aug;99-100:111688. (IF: 4.008)
28. Liu XY, Zhang X, Zhang Q, XieHL, Ruan GT, Liu T, Song MM, Ge YZ, Xu HX, Song CH, Shi HP. Value of theControlling Nutritional Status score in predicting the prognosis of patientswith lung cancer: A multicenter, retrospective study. JPEN J Parenter EnteralNutr. 2022 Aug;46(6):1343-1352. (IF: 4.016)
29. Li Y, Wang WB, Yang L, Wang QY,Dai J, Xia L, Peng J, Zhou FX, Wei YC, Shi HP. The combination of bodycomposition conditions and systemic inflammatory markers has prognostic valuefor patients with gastric cancer treated with adjuvant chemoradiotherapy.Nutrition. 2022 Jan;93:111464. (IF: 4.008)
30. Xie H, Ruan G, Wei L, Zhang H,Ge Y, Zhang Q, Lin S, Song M, Zhang X, Liu X, Yang M, Tang M, Song CH, Deng L, ShiH. Comprehensive comparison of the prognostic value of systemicinflammation biomarkers for cancer cachexia: a multicenter prospective study.Inflamm Res. 2022 Aug 13. (IF: 4.575)
31. Song M, Liu T, Liu H, Zhang Q,Zhang Q, Wang Y, Ma X, Cao L, Shi H. Association between metabolicsyndrome, C-reactive protein, and the risk of primary liver cancer: a largeprospective study. BMC Cancer. 2022 Aug 4;22(1):853. (IF: 4.430)
32. Jia P, Zhang Y, Xu J, Zhu M,Peng S, Zhang Y, Zhao J, Li X, Mi K, Yan D, Wang Y, Yu L, Lu Y, Shi H,Cen S. IMB-BZ as an Inhibitor Targeting ESX-1 Secretion System to ControlMycobacterial Infection. J Infect Dis. 2022 Feb 15;225(4):608-616. (IF: 5.226)
33. Yin L, Song C, Cui J, Lin X, LiN, Fan Y, Zhang L, Liu J, Chong F, Wang C, Liang T, Liu X, Deng L, Yang M, YuJ, Wang X, Liu X, Yang S, Zuo Z, Yuan K, Yu M, Cong M, Li Z, Weng M, Yao Q, JiaP, Li S, Guo Z, Li W, Shi H, Xu H. De novo Creation and Assessment of aPrognostic Fat-Age-Inflammation Index "FAIN" in Patients With Cancer:A Multicenter Cohort Study. Front Nutr. 2022 Apr 13;9:860285. (IF: 6.576)
34. Yin L, Zhang L, Li N, Guo J,Liu L, Lin X, Fan Y, Liu J, Zhang M, Chong F, Chen X, Wang C, Wang X, Liang T,Liu X, Deng L, Li W, Yang M, Yu J, Wang X, Liu X, Yang S, Zuo Z, Yuan K, Yu M,Song C, Cui J, Li S, Guo Z, Shi H, Xu H. Several anthropometricmeasurements and cancer mortality: predictor screening, thresholddetermination, and joint analysis in a multicenter cohort of 12138 adults. EurJ Clin Nutr. 2022 May;76(5):756-764. (IF: 4.016)
35. Zhuang CL, Dong QT, Shi HP,Zhang FM, Luo X, Wang WB, Yu Z, Chen XL, Wang SL. Cachexia Versus Sarcopenia inClinical Characteristics and Prognostic Value After Radical Gastrectomy forGastric Cancer: A Large-Scale Prospective Study. Ann Surg Oncol. 2022Apr;29(4):2348-2358. (IF: 5.344)
36. Yin L, Song C, Cui J, Wang N,Fan Y, Lin X, Zhang L, Zhang M, Wang C, Liang T, Ji W, Liu X, Li W, Shi H,Xu H; Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC) Group. Low fat mass index outperforms handgrip weakness andGLIM-defined malnutrition in predicting cancer survival: Derivation of cutoffvalues and joint analysis in an observational cohort. Clin Nutr. 2022Jan;41(1):153-164. (IF: 7.324)
37. Yin L, Fan Y, Lin X, Zhang L,Li N, Liu J, Guo J, Zhang M, He X, Liu L, Zhang H, Shi M, Chong F, Chen X, WangC, Wang X, Liang T, Liu X, Deng L, Li W, Song C, Cui J, Shi H, Xu H;Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC) Group. Fat mass assessment using the triceps skinfold thicknessenhances the prognostic value of the Global Leadership Initiative onMalnutrition criteria in patients with lung cancer. Br J Nutr. 2022 May28;127(10):1506-1516. (IF: 3.718)
38. Xue H, Du H, Xie Y, Zhai Y,Song S, Luo B, Qiu H, Wang K, Cui J, Song C, Xu H, Li W, Shi H, Li Z;Investigation on Nutrition Status and Its Clinical Outcome of Common Cancers(INSCOC) Group. Association Between Fat Mass to Lean Body Mass Ratio andAll-Cause Mortality Among Middle-Aged and Elderly Cancer Patients WithoutObesity: A Multi-Center Observational Study in China. Front Nutr. 2022 Jun16;9:914020. (IF: 6.576)
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学校介绍
首都医科大学建校于1960年，是北京市重点高等院校，著名泌尿外科专家、中国科学院院士、中国工程院院士、原全国人大常委会副委员长吴阶平教授为首任院长。学校由校本部和附属医院(即临床医学院)组成。校本部设有基础医学院、生物医学工程学院、公共卫生与家庭医学学院、高等职业教育学院、中医药学院、顺义校区、继续教育学院、护理学院、卫生事业管理与发展学院及首都医科大学国际教学部；附属医院包括宣武医院(第一临床医学院)、附属北京友谊医院(第二临床医学院)、附属北京朝阳医院(第三临床医学院)、附属北京同仁医院(第四临床医学院)、附属北京天坛医院(第五临床医学院)、附属北京安贞医院(第六临床医学院)、附属北京口腔医院(口腔医学院)、附属北京儿童医院(儿科医学院)、附属北京妇产医院(妇产医学院)、附属北京安定医院(精神卫生学院)、附属复兴医院(第八临床医学院)、附属北京中医医院(中医药临床医学院)和康复医学院。
学校和附属医院现有教职员工和医护人员22575人。有院士4人，正高职称700余人，副高职称1800余人。学校学科专业齐全，学科力量雄厚，在基础和临床各专业拥有一大批具有很高造诣的专家学者，现有3个国家级重点学科，有38个博士学位授予权学科，58个硕士学位授予权学科和2个博士后科研流动站。
校本部和附属医院总占地面积97.3万平方米，总建筑面积134万平方米 ，固定资产总值近46.5亿元，图书馆藏书108.3万册 ，住院病床10039张。学校开办的七年制专业中设有临床医学和口腔医学；五年制专业中设有临床医学、口腔医学、预防医学、护理学、中医学等；四年制专业中设有生物医学工程、中药学和康复治疗学。在临床医学专业中设有儿科医学、康复医学、医学影像、精神卫生与精神病学和医学检验5个专业方向；在生物医学工程专业中设有医学影像设备与技术和听力学专业方向。高等职业教育设有护理、医学检验、药学、医学影像技术、康复技术、口腔修复工艺、眼科验光、实验动物技术、中医学、中药制剂、医学信息、临床医学、预防医学、中药经营贸易和中医学美容专业方向15个专业。首都医科大学现已成为以培养高层次本科生与研究生为核心、以临床应用型人才为主和培养预防、康复、生物医学工程和医学基础各学科、各层次人才，位于全国先进医学院校行列的高等学府。
学校具有较强的学术发展与科研实力，在校本部和附属医院建有一批国家级和市级重点学科和重点实验室，建有高水平的国家级或市级研究和培训机构，如卫生部全科医学培训中心、临床医学研究所、基础医学研究所、神经科学研究所、眼科研究所、老年病医疗研究中心、泌尿外科研究所、心肺血管医疗研究中心、生命科学院、卫生毒理检测中心、生物工程技术研究中心、祖国医学研究所、临床疾病研究中心、中医肝病临床研究中心、生殖医学研究所、心血管疾病临床试验及社区干预中心和北京市卫生政策与卫生经济研究中心等。神经生物学、细胞生物学、电生理学、基础免疫学、实验寄生虫学、医学图像处理、生物医学、信息检测与处理、神经内科、神经外科、心脏内外科、肾移植、呼吸和消化内科、口腔颌面外科、眼科、耳鼻咽喉科、小儿血液病等领域在国内外享有较高声誉，很多学科的研究和医疗水平已经达到或接近国际先进水平。
学校十分重视对外交流与合作，改革开放以来，先后与世界20多个国家和地区签定了友好交流协议， 近十年中,先后接待美国、加拿大、英国、澳大利亚、法国、瑞典、日本、荷兰、意大利、德国、丹麦及台湾、香港和澳门等50多个国家和地区的专家学者8000余人次来校进行学术交流和参观访问。同时，学校积极选送教师、科研人员和管理干部出国进修、参加学术会议和考察访问。
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