个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
主任医师、首都医科大学教授、博士生导师。从事骨肿瘤专业临床科研工作30余年，为积水潭医院骨肿瘤学科骨干，承担大量临床诊疗任务、北京大学医学部临床教学和全国骨科进修班教学任务，协助培养多名硕士生和博士生。注重临床资料的总结分析和骨肉瘤、骨巨细胞瘤长期随访，结合基础研究和高新技术进展，获得对临床工作有指导意义的结论，参与了近三十年骨肿瘤科全部科研工作，在骨与软组织肿瘤外科治疗方面有丰富的临床实践经验，近十年在国内率先实践计算机辅助导航技术应用于骨与软组织肿瘤外科切除与重建，累计参与相关手术1500余例，在国内、乃至国际的骨肿瘤专业中实践病例数最多。作为主要完成人参与了北京市科委组织的《骨肉瘤综合治疗的基础与临床研究》（2001-2004）、《肌骨系统肿瘤的磁共振振子波谱研究》（2006-2009）、《骨与软组织肿瘤遗传信息库的建立与应用》（2006-2009）等科研项目。作为该课题的负责人，主要完成国家自然基金《骨肿瘤手术的医学影像导航系统关键技术研究》（2012-2015）、北京市科委首都特色《大剂量甲氨蝶呤化疗应用及严重毒副作用处理临床规范的建立》（2013-2016）、北京市首发基金《计算机辅助导航技术和ＭＩＭＩＣＳ技术在骨肿瘤精确切除个体化人工加体制作保留肢体的外科治疗应用研究》（2012-2015）等课题的计划制定与执行监督、合作双方的协调、最终临床验证实验的实施及效果的评价等工作。目前主持国家自然科学基金面上项目 62171017 《计算机导航骨肿瘤手术中肿瘤分割与切面规划研究》（2022.1.1-2025.12.31）。
国家自然科学基金委，计算机导航骨肿瘤手术中肿瘤分割与切割规划研究，国家级，62171017
北京市科学技术委员会，基于计算机导航或骨科机器人的保留关节骨肿瘤特制假体术前设计、制备及临床应用的研究，省部级，20220481079
国家自然科学基金委，计算机导航骨肿瘤手术中肿瘤分割与切割规划研究，国家级，62171017
北京市科学技术委员会，基于计算机导航或骨科机器人的保留关节骨肿瘤特制假体术前设计、制备及临床应用的研究，省部级，20220481079
1.Li Z, Li L, Deng Z, Yang Y, Duan F, Zhang Q, Niu X, Liu W. Long-term outcomes of computer navigation-assisted resection for primary pelvic sarcomas. Bone Joint J. 2025 May 1;107-B(5):561-570.
2.Li Z, Fan D, Zhao J, Deng Z, Yang Y, Jin T, Zhang Q, Niu X, Liu W. Is Proximal Tibial Hemiarthroplasty Reconstruction Effective in Minimizing Limb Length Discrepancy Among Skeletally Immature Patients With Primary Bone Sarcomas? Clin Orthop Relat Res. 2025 Nov 1;483(11):2163-2174.
3.Li Z, Fan D, Jin T, Sun Y, Li Y, Zhang Q, Niu X, Liu W. Is Ipsilateral Femoral Head Autograft Reconstruction Durable in Patients Undergoing Enneking II/II+III Tumor Resections at a Minimum 5-year Follow-up? Clin Orthop Relat Res. 2025 Oct 13.
4.Li Z, Fan D, Jin T, Sun Y, Li Y, Zhang Q, Niu X, Liu W. What Are the Long-term Outcomes of Wrist Arthrodesis Using Structural Iliac Bone Graft After Resection of the Distal Radius for Giant Cell Tumor of Bone? A Minimum 10-year Follow-up Clin Orthop Relat Res. 2025 Nov 13.
5.Li Z, Liu W, Jin T, Sun Y, Li Y, Niu X, Jiang C, Zhang Q. Comparison of Biological Reconstruction After Resection of Proximal Humerus Bone Sarcomas in Pediatric Patients. JB JS Open Access. 2025 Nov 14;10(4):e25.00159. doi: 10.2106/JBJS.OA.25.00159.
6.Li Z, Guo H, Deng Z, Yang Y, Zhang Q, Liu W. Comparison of survival, function and complication between intercalary frozen autograft versus massive allograft reconstruction after malignant bone tumors resection. J Orthop Traumatol. 2024 Nov 24;25(1):58.
7.Li Z, Zhao J, Fan D, Deng Z, Yang Y, Niu X, Zhang Q, Liu W. Soft tissue reconstruction of tumor-related proximal tibial hemiarthroplasty using synthetic mesh combined with a medial gastrocnemius flap. J Orthop Traumatol. 2025 Sep 26;26(1):58.
8.Li Z, Deng Z, Yang Y, Zhang Q, Niu X, Liu W. The survival, mechanisms of failure, and function after total humeral replacement in patients with primary sarcomas. J Shoulder Elbow Surg. 2025 Jun;34(6):e361-e370.
9.Li Z, Liu W, Hao L, Zhang Q, Niu X. The clinical outcomes and prognostic factors of dedifferentiated central chondrosarcoma in extremities. J Orthop Surg Res. 2024 Oct 3;19(1):621.
10.Li Z, Deng Z, Yang Y, Gao D, Zhang Q, Niu X, Liu W. Denosumab combined with en bloc resection and arthrodesis for recurrent grade 3 giant cell tumor of bone in distal radius. J Orthop Surg Res. 2024 Sep 28;19(1):607.
11.Li Z, Deng Z, Yang Y, Zhang Q, Niu X, Liu W. Is intercalary frozen autograft augmented with intramedullary cement and bridging plates fixation a durable reconstruction? J Orthop Surg Res. 2024 Nov 10;19(1):740.
12.Li Z, Liu W, Niu X, Jiang C, Zhang Q. The clinical outcomes of joint-preserving endoprosthesis reconstruction for primary sarcomas about the knee. J Orthop Surg Res. 2025 Sep 24;20(1):827.
13.Li Z, Fan D, Zhang Q, Liu W. Is the clavicla pro humero a reliable reconstruction for paediatric proximal humerus sarcomas? Int Orthop. 2025 Jan;49(1):271-278.
14.Zhang Q, Wang Z, Zeng X, Ding Y, Wang C. Evaluation of tumorous LCP1 and ADPGK as predictive biomarker for immune-related adverse events in bone and soft tissue sarcomas treated with anti-PD-1 and anti-PD-L1 antibodies. BMC Cancer. 2025 Apr 7;25(1):619.
15.Zhang Q, Li Y, Zhang Y, Deng Z, Ding Y. Case report of penile squamous cell carcinoma continuous treatment with BRCA2 mutation. World J Surg Oncol. 2024 Feb 9;22(1):50.
16.Zhang Q, Deng Z, Yang Y. Metastasis-Related Signature for Clinically Predicting Prognosis and Tumor Immune Microenvironment of Osteosarcoma Patients. Mol Biotechnol. 2023 Nov;65(11):1836-1845.
文件上传中...
