首都医科大学附属北京地坛医院拥有国家传染病医学中心（北京），国家级重点专科 5 个，建有北京市新发突发传染病临床样本与数据资源库。收治涵盖所有法定 40 种传染病。牵头成立感染性疾病专科联盟覆盖全国 90 余家医疗机构。主持5项国家级重大专项，形成突发急性传染病中医药防治方案等项目成果，为在重大传染病临床防治提供支撑。拥有国家感染病临床重点专科、国家中医药管理局中医传染病及中西医结合传染病重点学科。医院先后承担了非典、甲型H1N1 流感、新冠肺炎疫情等诊疗救治任务。

[1] *Yunlong Cao, Xiaohua Hao, Xi Wang, Qianhui Wu, Rui Song, Dong Zhao, Weiliang Song, Yao Wang, Ayijiang Yisimayi, Wei Wang, Wen Zhang, Juan Du, Hongjie Yu, *Xiaoliang Sunney Xie, *Ronghua Jin. Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine. Cell Res 2022;32(1):107-09. doi: 10.1038/s41422-021-00596-5 [published Online First: 2021/12/05]

[2] Rongjia Zhu, Tingdong Yan, Yingmei Feng, Yan Liu, Hongcui Cao, Gongxin Peng, Yanlei Yang, Zhen Xu, Jingqi Liu, Wei Hou, Xiaoyue Wang, Zhe Li, Luchan Deng, Shihua Wang, Jing Li, Qin Han, Hongling Li, Guangliang Shan, Yinghao Cao, Xingyan An, Jianshe Yan, Zhonghui Zhang, Huafei Li, Xuebin Qu, Jiaqi Zhu, Shumin Zhou, Jiao Wang, Fengchun Zhang, Jinming Gao, *Ronghua Jin, Dayong Xu, *Yan-Qing Ma, Tao Huang, Shuang Peng, Zhi Zheng, Ilia Stambler, Eric Gilson, Lee Wei Lim, Alexey Moskalev, Antonio Cano, Sasanka Chakrabarti, Brun Ulfhake, Huanxing Su, Haoying Xu, Sihuan Xu, Feng Wei, Holly M Brown-Borg, Kyung-Jin Min, Georgina Ellison-Hughes, Calogero Caruso, Kunlin Jin, *Robert Chunhua Zhao. Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms. Cell Res 2021;31(12):1244-62. doi: 10.1038/s41422-021-00573-y [published Online First: 2021/10/28]

[3] Xianwen Ren, Wen Wen, Xiaoying Fan, Wenhong Hou, Bin Su, *Kun Qu, *Xiaoqun Wang, *Jiekai Chen, *Ronghua Jin, *Zemin Zhang. COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas. Cell 2021;184(7):1895-913.e19. doi: 10.1016/j.cell.2021.01.053 [published Online First: 2021/03/04]

[4] Danlei Mou, Huahua Feng, Ruiyuan Cao, Xing Weng, Lizhe Zhao, Lingling Yang, *Ronghua Jin, *Weijun Chen. Profile of specific antibodies to the SARS-CoV-2. J Med Microbiol 2021;70(3) doi: 10.1099/jmm.0.001335 [published Online First: 2021/03/19]

[5] Jun Wu, Zhongjie Hu, Liu Wang, Yuanqing Tan, Wei Hou, Zhongwen Li, Tingting Gao, Jiaqi Fan, Baojie Guo, Huaping Dai, Wei Li, *Jie Hao, *Ronghua Jin, *Baoyang Hu. First case of COVID-19 infused with hESC derived immunity- and matrix-regulatory cells. Cell Prolif 2020;53(12):e12943. doi: 10.1111/cpr.12943 [published Online First: 2020/10/28]

[6] Bin Su , Jiming Yin, Xingguang Lin, Tiantian Zhang, Xiao Yao, Ying Xu, Yao Lu, Wenzhi Wang, Kun Liu, Jie Zhang, *Liangzhi Xie, *Ronghua Jin, *Yingmei Feng. Quantification of SARS-CoV-2 antigen levels in the blood of patients with COVID-19. Sci China Life Sci 2021;64(7):1193-96. doi: 10.1007/s11427-020-1830-8 [published Online First: 2020/12/02]

[7] Zhao Rongqing, Maohua Li, Hao Song, Jianxin Chen, Wenlin Ren, Yingmei Feng, George F Gao, Jinwen Song, Ya Peng, Bin Su, Xianghua Guo, Yanjun Wang, Jingong Chen, Jianli Li, Hunter Sun, Zhonghu Bai, Wenjing Cao, Jin Zhu, Qinlu Zhang, Yufei Sun, Sean Sun, Xinkun Mao, Junchi Su,Xiang Chen, Ailiang He, Wen Gao, *Ronghua Jin, *Yongzhong Jiang, *Le Sun. Early Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies as a Serologic Marker of Infection in Patients With Coronavirus Disease 2019. Clin Infect Dis 2020;71(16):2066-72. doi: 10.1093/cid/ciaa523 [published Online First: 2020/05/02]

[8] Yabo Ouyang, Jiming Yin, Wenjing Wang, Hongbo Shi, Ying Shi, Bin Xu, Luxin Qiao, Yingmei Feng, Lijun Pang, Feili Wei, Xianghua Guo, *Ronghua Jin, and *Dexi Chen. Downregulated Gene Expression Spectrum and Immune Responses Changed During the Disease Progression in Patients With COVID-19. Clin Infect Dis 2020;71(16):2052-60. doi: 10.1093/cid/ciaa462 [published Online First: 2020/04/21]

[9] Wenmin Tian, Nan Zhang, Ronghua Jin, Yingmei Feng, Siyuan Wang, Shuaixin Gao, Ruqin Gao, Guizhen Wu, Di Tian, *Wenjie Tan, *Yang Chen, *George Fu Gao, *Catherine C L Wong. Immune suppression in the early stage of COVID-19 disease. Nat Commun 2020;11(1):5859. doi: 10.1038/s41467-020-19706-9 [published Online First: 2020/11/19]

[10] Zhong-Jie Hu, Jia Xu, Ji-Ming Yin, Li Li, Wei Hou, Li-Li Zhang, Zhen Zhou, Yi-Zhou Yu, Hong-Jun Li, *Ying-Mei Feng, *Rong-Hua Jin. Lower Circulating Interferon-Gamma Is a Risk Factor for Lung Fibrosis in COVID-19 Patients. Front Immunol 2020;11:585647. doi: 10.3389/fimmu.2020.585647 [published Online First: 2020/11/03]

[11] Yunlong Cao, Bin Su, Xianghua Guo, Wenjie Sun, Yongqiang Deng, Linlin Bao, Qinyu Zhu, Xu Zhang, Yinghui Zheng, Chenyang Geng, Xiaoran Chai, Runsheng He, Xiaofeng Li, Qi Lv, Hua Zhu, Wei Deng, Yanfeng Xu, Yanjun Wang, Luxin Qiao, Yafang Tan, Liyang Song, Guopeng Wang, Xiaoxia Du, Ning Gao, Jiangning Liu, Junyu Xiao, Xiao-Dong Su, Zongmin Du, Yingmei Feng, *Chuan Qin, *Chengfeng Qin, *Ronghua Jin, *X Sunney Xie. Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells. Cell 2020;182(1):73-84.e16. doi:10.1016/j.cell.2020.05.025 [published Online First:2020/05/20]

[12] Chen Shao, Hui Liu, Lingjia Meng, Lin Sun, Yankun Wang, Zhujun Yue, Heli Kong, Hongjun Li, Honglei Weng, Fudong Lv, *Ronghua Jin. Evolution of severe acute respiratory syndrome coronavirus 2 RNA test results in a patient with fatal coronavirus disease 2019: a case report. Hum Pathol 2020;101:82-88. doi: 10.1016/j.humpath.2020.04.015 [published Online First: 2020/05/22]

[13] Zhenhuan Cao, Tongzeng Li, Lianchun Liang, Haibo Wang, Feili Wei, Sha Meng, Miaotian Cai, Yulong Zhang, Hui Xu, Jiaying Zhang, *Ronghua Jin. Clinical characteristics of Coronavirus Disease 2019 patients in Beijing, China. PLoS One 2020;15(6):e0234764. doi: 10.1371/journal.pone.0234764 [published Online First: 2020/06/20]

[14] Zhang Y , Qin L, Zhao Y , Zhang P , Xu B, Li K, Liang L, Zhang C, Dai Y , Feng Y , Sun J, Hu Z, Xiang H, Knight JC, * Dong T, *Jin R. Interferon-Induced Transmembrane Protein 3 Genetic Variant rs12252-C Associated With Disease Severity in Coronavirus Disease 2019. J Infect Dis 2020;222(1):34-37. doi: 10.1093/infdis/jiaa224 [published Online First: 2020/04/30]

[15] Hongbo Shi, Wenjing Wang, Jiming Yin, Yabo Ouyang, Lijun Pang, Yingmei Feng, Luxin Qiao, Xianghua Guo, Honglin Shi, *Ronghua Jin and *Dexi Chen. The inhibition of IL-2/IL-2R gives rise to CD8(+) T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia. Cell Death Dis 2020;11(6):429. doi: 10.1038/s41419-020-2636-4 [published Online First: 2020/06/10]

[16] Wenjing Wang, Bin Su, Lijun Pang, Luxin Qiao, Yingmei Feng, Yabo Ouyang, Xianghua Guo, Hongbo Shi, Feili Wei, Xiaogang Su, Jiming Yin, *Ronghua Jin, *Dexi Chen. High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients. Cell Mol Immunol 2020;17(6):650-52. doi: 10.1038/s41423-020-0447-2 [published Online First: 2020/04/30]

[17] Chi Zhang, Ling Qin, Kang Li, Qi Wang, Yan Zhao, Bin Xu, Lianchun Liang, Yanchao Dai, Yingmei Feng, Jianping Sun, Xuemei Li, Zhongjie Hu, Haiping Xiang, Tao Dong, *Ronghua Jin, *Yonghong Zhang. A Novel Scoring System for Prediction of Disease Severity in COVID-19. Front Cell Infect Microbiol 2020;10:318. doi: 10.3389/fcimb.2020.00318 [published Online First: 2020/06/26]

[18] Leng Z, Zhu R, Hou W, Feng Y , Yang Y , Han Q, Shan G, Meng F, Du D, Wang S, Fan J, Wang W, Deng L, Shi H, Li H, Hu Z, Zhang F, Gao J, *Liu H, Li X, Zhao Y , Yin K, He X, Gao Z, Wang Y , Yang B, *Jin R, Stambler I, Lim LW , Su H, Moskalev A, Cano A, Chakrabarti S, Min KJ, Ellison-Hughes G, Caruso C, *Jin K, *Zhao RC. Transplantation of ACE2(-) Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia. Aging Dis 2020;11(2):216-28. doi: 10.14336/ad.2020.0228 [published Online First: 2020/04/08]

[19] Ling Xu, Xiangying Zhang, Yuan Tian, Zihao Fan, Weihua Li, Mei Liu, Jianhua Hu, Zhongping Duan, *Ronghua Jin, Feng Ren. The critical role of PPARα in the binary switch between life and death induced by endoplasmic reticulum stress. Cell Death Dis 2020;11(8):691. doi: 10.1038/s41419-020-02811-4 [published Online First: 2020/08/23]

[20] Jing Huang, Can Cui, Shuli Zhou,Ming Chen, Hao Wu, *Ronghua Jin, and *Xinyue Chen. Impact of multicenter unified enhanced environmental cleaning and disinfection measures on nosocomial infections among patients in intensive care units. J Int Med Res 2020;48(8):300060520949766. doi: 10.1177/0300060520949766 [published Online First: 2020/08/22]