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陆慧，女，博士，副主任医师/副教授，现任职于首都医科大学宣武医院神经内科。2004—2012年就读于北京协和医学院八年制临床医学专业并获博士学位，2018—2019年赴美国哈佛大学医学院贝斯以色列女执事医院从事博士后研究。长期从事神经内科学临床与科研工作，研究方向聚焦于神经免疫疾病（如多发性硬化）、脑血管病免疫机制、朊蛋白病及疑难脊髓病的诊治，具有扎实的临床基础和持续稳定的科研产出。
在科研项目方面，近年来主持及参与多项国家级和省部级科研课题，包括国家自然科学基金青年项目、北京市属医院科研培育计划、北京市优秀人才培养资助青年骨干个人项目、北京市医院管理局“青苗”计划及首都医科大学校级和院级科研课题等，研究内容围绕神经免疫及神经退行性疾病的发病机制与早期诊断标志物，具有明确的临床转化价值。
在论文发表方面，以第一作者或通讯作者在Neurology、Molecular Neurobiology、Frontiers in Immunology、Journal of Alzheimer’s Disease等国际高水平期刊发表SCI论文10余篇，在国内核心期刊发表论文10余篇，部分研究成果被广泛引用，对多发性硬化、卒中后血脑屏障损伤及朊蛋白病早期诊断等领域具有重要学术影响。
在获奖方面，曾获北京市优秀住院医师、李绩住院医师奖，并获得中华医学会全国神经病学学术会议大会优秀壁报奖及Elsevier China TOP OA Author Award等奖项，体现了其在临床与科研领域的综合实力与学术影响力。
在论文发表方面，以第一作者或通讯作者在Neurology、Molecular Neurobiology、Frontiers in Immunology、Journal of Alzheimer’s Disease等国际高水平期刊发表SCI论文10余篇，在国内核心期刊发表论文10余篇，部分研究成果被广泛引用，对多发性硬化、卒中后血脑屏障损伤及朊蛋白病早期诊断等领域具有重要学术影响。
在获奖方面，曾获北京市优秀住院医师、李绩住院医师奖，并获得中华医学会全国神经病学学术会议大会优秀壁报奖及Elsevier China TOP OA Author Award等奖项，体现了其在临床与科研领域的综合实力与学术影响力。
科研项目方面，近年来主持及参与多项国家级和省部级科研课题，包括国家自然科学基金青年项目、北京市属医院科研培育计划、北京市优秀人才培养资助青年骨干个人项目、北京市医院管理局“青苗”计划及首都医科大学校级和院级科研课题等，研究内容围绕神经免疫及神经退行性疾病的发病机制与早期诊断标志物，具有明确的临床转化价值。
National Natural Science Foundation of China (2023-now), Mechanistic study of soluble interleukin-2 receptor α subunit in the genesis and development of multiple sclerosis through the activation of microglia, No. 82201489
Beijing Municipal Administration of Hospitals’ Cultivation Program (2020-2022), Early diagnosis and target study of alpha-synuclein in Creutzfeldt-Jakob disease, No. PX2021036
Beijing outstanding talents training and support for young backbone individual projects (2018-2020), No. 2017000020124G210
Natural Science Foundation of Capital Medical University (2018-2019), Early diagnosis of prion disease, No. PYZ2018060
Beijing Municipal Administration of Hospitals’ Youth Program (2016-2018), Study on diagnostic markers of preclinical and early clinical prion disease, No. QML20160802
1. Lu H, Ma YJ, Liu H, Li HF. Clinical Reasoning: A 49-Year-Old Woman With Isolated Sinus Intracranial Dural Arteriovenous Fistula With Perimedullary Drainage. Neurology. 2023. 100(19): 921-926.
2. Lu H, Ashiqueali R, Lin CI, et al. Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood-Brain Barrier After Stroke. Mol Neurobiol. 2023. 60(1): 235-246.
3. Zhang W, Wu P, Yin R, et al. Mendelian Randomization Analysis Suggests No Associations of Herpes Simplex Virus Infections With Multiple Sclerosis. Front Neurosci. 2022. 16: 817067.
4. Lu H, Wu PF, Zhang W, et al. Growth Factors and Their Roles in Multiple Sclerosis Risk. Front Immunol. 2021.12:768682.
5. Lu H, Wu PF, Ma DL, et al. Circulating Interleukins and Risk of Multiple Sclerosis: A Mendelian Randomization Study. Front Immunol. 2021. 15(12):647588.
6. Wu PF, Lu H*, Zhou X, et al. Assessment of causal effects of physical activity on neurodegenerative diseases: A Mendelian randomization study. J Sport Health Sci. 2021. 10(4): 454-461.
7. Lu H, Wu PF, Li RZ, et al. Relationships between accelerometer-measured and multiple sclerosis: a 2-sample Mendelian randomization study. Neurol Sci. 2021. 42(8): 3337-3341.
8. Jing DL, Chen YJ, Lu H, et al. White Matter Integrity Involvement in the Preclinical Stage of Familial Creutzfeldt-Jakob Disease: A Diffusion Tensor Imaging Study. Front Aging Neurosci. 2021; 13:655667.
9. Wu P, Li R, Zhang W, Lu H*. Mendelian randomization analysis does not support a role for leptin in multiple sclerosis. Mult Scler. 2021. 27(1): 160-161.
10. Lu H, Jing DL, Chen YJ, et al. Metabolic Changes Detected by 18F-FDG PET in the Preclinical Stage of Familial Creutzfeldt-Jakob Disease. J Alzheimers Dis. 2020. 77(4):1513-1521.
11. Lu H, Wu PF, Li R, et al. Sleep Duration and Stroke: a Mendelian Randomization Study. Front Neurol. 2020. 11: 976.
12. Lu H, Wu PF, Zhang W, et al. Coffee consumption is not associated with risk of multiple sclerosis: A Mendelian randomization study. Mult Scler Relat Disord 2020. 44:102300
13. Matheson R, Chida K, Lu H, et al. Neuroprotective Effects of Selective Inhibition of Histone Deacetylase 3 in Experimental Stroke. Transl Stroke Res. 2020. 11(5): 1052-1063.
14. Huang GX, Lu H, Yong Z, et al. Association between Cystatin C and SVD in Chinese population. Neurol Sci, 2018. 39(12):2197-2202.
15. Wu LY, Zhan SQ, Huang ZY, Zhang B, Wang T, Liu CF, Lu H et al. Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia. Chin Med J (Engl), 2018. 131(13):1613-1617.
16. Wu L1, Lu H1, Wang X, et al. Clinical Features and Sleep Analysis of Chinese Patients with Fatal Familial Insomnia. Sci Rep. 2017. 7(1):3625.
17. Lu H, Li Y, Sadowsky M, et al. Clinical characteristics of 37 Chinese patients with myotonic dystrophy Type 1. Brain Circulation. 2016. 2:95-8.
18. Lu H, Wang XB, Tang Y. Subdural Hematoma Associated with High Altitude. Chinese Medical Journal. 2015. 128(3): 4016007-408.
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