个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
主持多项国家级和省部级科研课题。国自然面上项目（82471498）网络控制理论指导下皮层－海马多靶点电磁调控改善AD患者认知功能的机制研究。国家重点研发计划（2022YFC2402205）无创多模电磁精准调控技术治疗老年痴呆和抑郁症的临床研究。国家自然科学基金委员会与芬兰科学院合作交流项目（82211530041）阿尔茨海默病临床前期患者β淀粉样蛋白PET定量分析和MRI影像组学特征的合作研究。北京市首都卫生发展科研专项自主创新项目（首发2022－2－2014）基于个体化fMRI定位新技术精准引导的rTMS治疗轻度认知障碍的研究。拓展新技术的临床应用，增加经颅电刺激和磁刺激、经颅磁刺激联合脑电图等特色诊断治疗新技术。多项研究结果发表在了EuropeanJ of Neurology（IF:6.089）、Brain Stimulation（IF:8.955）、NPJ parkinson disease（IF:9.304）等国外著名SCI杂志。学术成果积极投稿国外和国内学术组织的交流大会。
| 排序 | 起始时间 | 终止时间 | 项目名称 | 项目来源 | 项目类别 | 项目级别 | 立项总经费（万元） | 本人可支配经费（万元） | 本人排名 | 完成情况 |
| | 2025.01 | 2028.12 | 网络控制理论指导下皮层－海马多靶点电磁调控改善AD患者认知功能的机制研究 | 国家自然科学基金面上项目 | 自然类 | 国家级 | 49.00 | 49.00 | 1 | 在研 |
| | 2022.11 | 2026.10 | 无创多模电磁精准调控技术治疗老年痴呆和抑郁症的 临床研究 | 国家重点研发计划 | 自然类 | 国家级 | 180.00 | 124.00 | 1 | 在研 |
| | 2022.03 | 2024.12 | 阿尔茨海默病临床前期患者β淀粉样蛋白PET定量分析和MRI影像组学特征的合作研究 | 国家自然科学基金委员会与芬兰科学院合作交流项目 | 自然类 | 国家级 | 10.00 | 10.00 | 1 | 结题 |
| | 2022.01 | 2024.12 | 基于个体化fMRI定位新技术精准引导的rTMS治疗轻度认知障碍的研究 | 北京市首都卫生发展科研专项自主创新项目 | 自然类 | 省部级 | 41.60 | 41.60 | 1 | 结题 |
1. Yuxuan Shao,Lin Liu, Shuxiang Zhu, Ziyan Zhu, Pan Wang*, Bharat B. Biswal*, Hua Lin*(共同通讯）. Fornix MediatesInformation Propagation in Brain Networks Following DLPFC- Targeted rTMS inAlzheimer's Disease: A Randomized Controlled Trial. CNS Neuroscience &Therapeutics, 2025, 31: e70630. IF: 5.0
2. Hua Zhu,Shuxiang Zhu, Meixin Zhao, Ziyan Zhu, Yuxuan Shao, Xinxi Lu, Tao Liu, Haogang Zhu,Ni Shu, Hua Lin* (共同通讯）, Jian Cheng*. Cerebellar and BrainstemWhite Matter Geometric Alterations in Multiple System Atrophy: A DFA- BasedBiomarker for Disease Staging. CNS Neuroscience & Therapeutics, 2025, 31: e70623.IF: 5.0
3. ChengxiaoYang, Pan Wang*, Ziyan Zhu, Hao Wu, Qin Su, Shuxiang Zhu, Yuxuan Shao, Hua Lin*(共同通讯） and Bharat B. Biswal*. Individualizedfunctional connectome biomarkers predict clinical symptoms after rTMS treatmentin Alzheimer's disease. Translational Psychiatry, 2025, 15: 511. IF:6.2
4. WeiyuMeng , Ziyan Zhu , Zhen Wu, Shuxiang Zhu, Cheng Zhang , Changzhe Wu , XiaolinHuo,* , Hua Lin,* (共同通讯）, Guanghao Zhang * , forthe Alzheimer’s Disease Neuroimaging Initiative. Anatomically mediatedvariability of hippocampal electric ffelds in temporal interferencestimulation: A predictive modeling approach. NeuroImage ,2026, 325: 121641. IF:7.4
5. NianshuangWu, Yuxuan Shao, Zhen Wu, Shuxiang Zhu, Penghao Wang, Ziyan Zhu, Cheng Zhang,Changzhe Wu, Xiaolin Huo, Hua Lin *(共同通讯）, Guanghao Zhang*. Electric ffeld variations acrossDLPFC targeting methods in TMS therapy for Alzheimer’s disease.NeuroImage:Clinical, 2025,48:103847. IF:4.891
6. PenghuiSon, Siran Li, Yuxuan Shao, Shuxiang Zhu, Yuping Wang, Peng X *, Hua Lin*(共同通讯）. HF-rTMS of the left DLPFC relieve headaches andenhance frontal-temporal connectivity in migraine. Clinical Neurophysiology, 2025,173:166–172. IF:4.867
7. JunhuaLian, Qianqian Wang, Jiahao Wang, Yuxuan Shao, Shuxiang Zhu, Nianshuang Wu,Xiaolin Huo, Guanghao Zhang* and Hua Lin*(共同通讯）. Individual electricfield in cortical white matter is correlated with cognitive improvement inpatients with mild cognitive impairment due to Alzheimer’s disease afterrepetitive transcranial magnetic stimulation treatment.Journal of AlzheimersDisease, 2025,1-13. IF:3.800
8. YingxueYang#, Ziyan Zhu#, Yajie Wang, Yueshan Piao, Hua Lin*（通讯作者）. Systemic anaplasticlymphoma kinase-negative anaplastic large cell lymphoma with prominentmeningeal involvement: A case report. Journal of Neuropathology &Experimental Neurology, 2025, 1–5. IF:3.0
9. LuyaoWang, Wenjing Hu, Huanxin Wang, Ziyan Song, Hua Lin*(共同通讯）, Jiehui Jiang*. Differentstimulation targets of rTMS modulate specific triple- network andhippocampal-cortex functional connectivity. Brain Stimul. 2024, 17:1256–1264. IF:8.955
10. Hua Lin#,Junhua Liang#, Qianqian Wang, Yuxuan Shao, Penghui Song, Siran Li,Yang Bai. Effects of accelerated intermittent theta-burst stimulation inmodulating brain of Alzheimer’s disease. Cerebral Cortex, 2024 Mar 1;34(3): bhae106.IF:4.6
11. Tong Qin#,Luyao Wang#, Huanyu Xu#,Chunyan Liu, Yuxuan Shao, Fangjie Li, YupingWang,Jiehui Jiang, Hua Lin*（通讯作者）. TMSconcurrent with cognitive training rewires AD brain by enhancing GM-WM functionalconnectivity: a preliminary study. CerebralCortex, 2024 Jan 14;34(1):bhad460. IF:4.6
12. Zhuoyuan Li#, HuaLin #(共同第一), Qi Zhang, Rong Shi,Huanyu Xu, Fan Yang , Xueyan Jiang, Luyao Wang,Ying Han* and Jiehui Jiang. IndividualProportion Loss of Functional Connectivity Strength: A Novel IndividualFunctional Connectivity Biomarker for Subjective Cognitive Decline Populations.Biology 2023, 12, 564. IF:5.168
13. Hua Lin#*（通讯作者）, Li Lin#, Lyuan Xu, Siran Li, Penghui Song, Muwei Li. Combinedfunctional and structural imaging of brain white matter reveals stage-dependentimpairment in multiple system atrophy of cerebellar type. npj ParkinsonsDisease. 2022,8:105. IF:9.304 Q1区
14. Jin G, Chen J, Du J, He L, Qi L, Wu D, Wang Y, Lin H*(共同通讯）, Ren L*. Repetitive transcranial magneticstimulation to treat benign epilepsy with centrotemporal spikes. Brain Stimul.2022,15: 601-604. IF:8.955 Q1区
15. Hua Lin#, Jiehui Jiang#, Zhuoyuan Li,Can Sheng, Wenying Du, Xiayu Li, Ying Han*. Identification of SubjectiveCognitive Decline due to Alzheimer’s disease Using Multimodal MRI combiningwith machine learning. Cerebral Cortex, 2023 Jan 5;33(3):557-566. doi:10.1093/cercor/bhac084.. IF:5.357 Q1区
16. Gong M, Wang S, Lin H∗. Postural instability andbackward leaning in a patient of familial fatal insomnia with positive SOX1antibodies. Sleep Med. 2022 Feb 18;91:59-61. IF: 4.609 Q2区
17. Lianghui Ni, MingyanZhao, Zhishan Hu, Kun Yang, Xing Zhao, HaijingNiu∗ and Hua Lin∗. Neural Mechanism of Shentai Tea Polyphenols onCognitive Improvements for Individuals with Subjective Cognitive Decline: AFunctional Near-Infrared Spectroscopy Study. Journal of Alzheimers Disease,2021,82: 1137–1145. IF:4.472 Q2区
18. Hua Lin,Muwei Li, Yang Zhan, Li Lin, Kun Yang, Shimin Hu,Ying Han. Disrupted whitematter functional connectivity in aMCI APOEε4 carriers: a resting-state study.Brain Imaging and Behavior, 2021 Aug;15(4): 1739-1747. IF:3.978 Q3区
文件上传中...
