• （1）国家自然科学基金委员会，面上项目，82572469，ATF6介导树突状细胞泛凋亡在脓毒症免疫应答紊乱中作用及机制研究，2026-01-01至2029-12-31，49万元，在研，主持
• （2）国家自然科学基金委员会，面上项目，82272187，CD80+CD274+mregDC功能及分化在脓毒症免疫应答紊乱中作用与调控机制，2023-01-01至2026-12-31，52万元，在研，主持
• （3）国家自然科学基金委员会，面上项目，82172124，中枢冷诱导RNA结合蛋白在调节脓毒症外周细胞免疫中的作用及机理，2022-01-01至2025-12-31，54万元，在研，参与
• （4）国家自然科学基金委员会，重点项目，82130062，Sestrin2通过调节内质网/线粒体选择性自噬介导脓毒症中树突状细胞免疫效应及其信号机制，2022-01-01至2026-12-31，290万元，在研，参与
• （5）北京市临床医师科学家培训项目北京市卫健委BJPSTP-2024-22024-0550万元。

1.  Clinical features and development of sepsis in patientsinfected with 2019 novel coronavirus: a retrospective analysis of 150 casesoutside Wuhan, China. Intensive Care Med, 2020,DOI: 10.1007/s00134-020-06084-5. 

2.  Organelle-specific autophagy in inflammatory diseases: a potential therapeutic targetunderlying the quality control of multiple organelles. Autophagy, 2020, DOI:10.1080/15548627.2020.1725377.

3.Sepsis associated encephalopathy: a vicious cycle for immuno-suppression. JNeuroinflamm, 2020, 17(1):14. 

4.Publication trends of research on sepsis and hostimmune response during 1999-2019: a 20-year bibliometric analysis. Int J BiolSci, 2020, 16(1): 27-37. 

5. Inhibition of cerebral high-mobilitygroup box 1 protein attenuates multiple organ damage and improves Tcell-mediated immunity in septic rats. Mediat Inflamm, 2019, 2019: 6197084.

6. Autophagy: a potential therapeutic target for reversingsepsis-induced immunosuppression. Front Immunol, 2017, 8: 1832. 

7. Activation of central alpha 7 nicotinic acetylcholinereceptor reverses suppressed immune function of T lymphocytes and protectsagainst sepsis lethality. Int J Biol Sci, 2018, 14(7): 758-759.

8. The protective effect of alpha 7 nicotinic acetylcholine receptor activation oncritical illness and its mechanism. Int J Biol Sci, 2017, 13(1): 46-56. 

9. Is hemoglobin below 7.0 g/dl an optimal trigger forallogenic red blood cell transfusion in patients admitted to intensive careunits? a meta-analysis and systematic review. BMJ open, 2020, 10(2): e030854.

10. Is intensive glucose control really bad for criticallyill patients? a systematic review and meta-analysis. Int J Biol Sci, 2020,16(9): 1658-1675.

11. Clinicalefficiency of vasopressin or its analogues in comparison with catecholaminesalone on patients with septic shock: a systematic review and meta-analysis.Front Pharmacol. 2020, 11: 563. 

12.A machinelearning-based prediction of hospital mortality in patients with postoperativesepsis. Frontiers in Medicine. 2020;7:445. doi: 10.3389/fmed.2020.00445.

13.  Lysosomal quality control of cell fate:a novel therapeutic target for human diseases. Cell Death Dis. 2020;11(9):817.doi: 10.1038/s41419-020-03032-5.

14. Comparison of clinical laboratory tests between bacterial sepsisand SARS-CoV-2-associated viral sepsis. Mil Med Res. 2020; 7(1):36. doi:10.1186/s40779-020-00267-3.

15.The Clinical Features and Prognostic Assessmentof SARS-CoV-2 Infection-Induced Sepsis Among COVID-19 Patients in Shenzhen, China.Frontiers in Medicine. 2020; 7: 570853.

16.  Sestrin2 protects against lethal sepsis by suppressing thepyroptosis of dendritic cells.Cell Mol Life Sci.. 2021,78(24):8209-8227. 

17.The Role and Regulatory Mechanism of TranscriptionFactor EB in Health and Diseases. Front Cell Dev Biol. 2021, 9:667750.

18. Antagonism ofCerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction inSepsis. Front Pharmacol.2021,12:665579. 

19. De Ritis Ratio as a Significant Prognostic Factor in Patientswith Sepsis: A Retrospective Analysis. J Surg Res. 2021,264:375-385. 

20. Development of septic shockand prognostic assessment in critically ill patients with coronavirus diseaseoutside Wuhan, China. World J Emerg Med. 2021,12(4):293-298.

21.  Artificial intelligence insmall intestinal diseases: Application and prospects. World J Gastroenterol. 2021,27(25):3734-3747. 

22.  The microbiologicaldiagnostic performance of metagenomic next-generation sequencing in patientswith sepsis. BMC Infect Dis. 2021,21(1):1257. 

23.  Sepsis-Associated Coagulopathy Predicts Hospital Mortality inCritically Ill Patients With Postoperative Sepsis. Frontiers in Medicine.2022,9.0.3389/fmed.2022.783234.

24. Advances in Immune Monitoring Approaches for Sepsis-Induced Immunosuppression.Front Immunol. 2022,13:891024. doi: 10.3389/fimmu.2022.891024.

25.  Eukaryotic ribosome qualitycontrol system: a potential therapeutic target for human diseases. Int J BiolSci 2022; 18(6):2497-2514.

26. Application Status andProspects of Artificial Intelligence in Peptic Ulcers. Front Surg. 2022,9:894775. doi: 10.3389/fsurg.2022.894775.

27. Single-celltranscriptome profiling of the immune space-time landscape reveals dendriticcell regulatory program in polymicrobial sepsis. Theranostics. 2022,12(10):4606-4628.doi: 10.7150/thno.72760.

28. Expert consensus on the monitoring and treatment of sepsis-inducedimmunosuppression. Mil Med Res, 2022, 9(1):74. doi: 10.1186/s40779-022-00430-y.

29. The crosstalk betweenmitochondrial quality control and metal-dependent cell death. Cell Death Dis.2024;15(4):299. doi: 10.1038/s41419-024-06691-w. IF 6.8

30.Advances in Immune Monitoring Approaches for Sepsis-InducedImmunosuppression. Front Immunol, 2022, 13:891024. doi:10.3389/fimmu.2022.891024. eCollection 2022.

31.  Neutrophilmembrane-mimicking nanodecoys with intrinsic anti-inflammatory propertiesalleviate sepsis-induced acute liver injury and lethality in a mouse endotoxemiamodel. Mater Today Bio. 2022,14:100244. doi: 10.1016/j.mtbio.2022.100244. 

32. Time-resolvedsingle-cell transcriptomics reveals the landscape and dynamics of hepatic cellsin sepsis-induced acute liver dysfunction. JHEP Rep. 2023 Mar 1;5(6):100718.doi: 10.1016/j.jhepr.2023.100718. 

33.  Pharmacologicallysignificant constituents collectively responsible for anti-sepsis action ofXueBiJing, a Chinese herb-based intravenous formulation. Acta Pharmacol Sin,2024 May;45(5):1077-1092. doi: 10.1038/s41401-023-01224-1.

34 . EXPLORING THE POTENTIAL OF BEND7 AS AN IMMUNOMODULATORY BIOMARKER INSEPSIS THROUGH INTEGRATIVE GENOMIC AND TRANSCRIPTOMIC ANALYSIS. Shock. 2025 Jun1;63(6):826-835.