个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
致力于神经免疫疾病的诊治，入选首届国家优秀青年医师。作为主要执行者建设神经免疫研究型病房，践行将科研植入临床的理念，打造神经免疫专病全流程管理。围绕神经炎症，从“人群-队列-干预”三个维度进行探索。通过大数据和时空分析，首次全面描述中国31省直辖市神经免疫疾病的发病率，丰富了该类疾病的全球流行病学版图；合作建立中国神经炎性疾病登记队列（CNRID），国内首次系统的将超高场强磁共振7T MRI应用于神经炎性疾病，阐述神经炎症驱动神经免疫疾病的特征。基于对经典神经免疫理论的理解，创新脑损伤后靶向干预神经炎症临床实践。在Lancet Regional Health，Annals of Neurology，Brain，JACC. Cardiovasc Imaging, J Neurol Neurosurg Psychiatry等杂志发表论文。发明专利3项。主持北京市自然杰出青年基金及国家自然科学基金2项。作为主要参与者，获得北京市科技进步一等奖和天津市自然科学奖一等奖。
1、北京市自然科学基金杰出青年科学基金，《通过神经影像结合神经病理的宏观--微观跨尺度探索神经炎症的全脑扩散机制》，在研；
2、国家自然科学基金面上项目，《B淋巴细胞介导的免疫反应在原发性中枢神经系统血管炎发病机制中的作用及临床意义》，在研；
3、首医优秀青年人才项目A类，《神经炎症与脑疾病》，在研；
4、天坛医院临床研究重点攻关项目B类，《进展性多发性硬化的机制研究和精准诊疗》，在研；
5、国家自然科学基金青年科学基金项目，《小胶质细胞来源的IL-6和C1q在视神经脊髓炎谱系疾病的作用及机制研究》，结题。
2020-10 - ：首都医科大学附属北京天坛医院
2018-05 - 2020-08：首都医科大学附属北京天坛医院 (博士后)
2011-07 - 2018-03：天津医科大学总医院
2008-09 - 2011-07：首都医科大学
2003-09 - 2008-07：青岛大学医学院
1. Guo A#, Zhang Z#, Dong GH, Su L, Gao C, Zhang M, Shi X, Wang H, Zhang X, Lu DH, Fu Y, Jing J*, Shi FD*,Tian DC*.Cortical Microhemorrhage Presentation of Small Vessel Primary Angiitis of the Central Nervous System. Annals of Neurology. 2024.96(1):194-203.
2. Xu Y#, Meng H#, Fan M, Yin L, Sun J, Yao Y, Wei Y, Cong H, Wang H, Song T, Yang CS, Feng J, Shi FD,Zhang X*, Tian DC*. A Simple Score (MOG-AR) to Identify Individuals at High Risk of Relapse After MOGAD Attack. Neurol Neuroimmunol Neuroinflamm.2024 Nov;11(6):e200309.
3. Jing J#, Zhang Z#, Su L#, Gao C, Guo A, Liu X, Wang H, Zhang X, Liu Y, Comi G, Waubant E, Shi FD, Tian DC*. Central vein sign and trigeminal lesions of multiple sclerosis visualised by 7T MRI. J Neurol Neurosurg Psychiatry. 2024.95(8):761-766.
4. Sun J#, Guo M#, Chai L#, Xu S#, Lizhu Y, Li Y, Duan Y, Xu X, Lv S, Weng J, Li K, Zhou F, Li H, Li Y, Han X, Shi FD, Zhang X, Tian DC*, Zhuo Z*, Liu Y*. Distinct virtual histology of grey matter atrophy in four neuroinflammatory diseases. Brain. 2024.147(11):3906-3917.
5. Tian DC, Li ZX, Yuan M, Zhang CY, Gu HG, Wang YJ, Shi, FD*. Incidence of neuromyelitis optica spectrum disoder(NMOSD) in China: A national population-based study. Lancet regional health-Western Pacific. 2020; 2: 100021.
6. Tian DC, Zhang CY, Yuan M, Yang X, Gu HQ, Li ZX, Wang YJ, Shi FD*. Incidence of multiple sclerosis inChina: A nationwide hospital-based study. Lancet regional health-Western Pacific. 2020; 1: 100010.
7. Zheng P#, Tian DC#, Xiu YW, Wang YJ, Shi FD*. Incidence of Guillain-Barré syndrome (GBS) in China: A national population-based study. Lancet regional health-Western Pacific. 2021 Nov 2;18:100302.
8. Chen JS, Tian DC, Zhang C, Li ZX, Zhai Y, Xiu YW, Gu HG, Li H*, Wang YJ*, Shi, FD*. Incidence,mortality, and economic burden of myasthenia gravis in China: A nationwide population-based study. Lancet regional health-Western Pacific. 2020; 4: 100063.
9. Shi KB, Tian DC, Li ZG, Ducruet AF, Lawton MT and Shi FD*. Global brain inflammation in stroke. LancetNeurology. 2019 Nov;18(11): 1058-1066.
10. Tian DC, Shi KB, Zhu ZL, Yao J, Yang X, Su L, Zhang S, Zhang M, Gonzales R, Liu Q, Ducruet AF, Waters MF, Huang DR, Sheth KN, Fu Y, Lou M, Shi FD*. Fingolimod enhances alteplase efficacy in acute ischemic stroke within 4.5-6 hours via promoting anterograde reperfusion and retrograde collateral flow. Annals of Neurology. 2018 Nov;84(5):717-728.
11. Tian DC, Zhu XD, Xue R, Zhao P, Yao YR*. Case 259: Primary Central Nervous System Lymphomatoid Granulomatosis Mimicking Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS). Radiology. 2018 Nov;289(2):572-577.
12. Kang HB#, Tian DC#, Yang XJ, Zhang YS, Li WQ, Sui B, Duan Y, Zhang Y, Liu J, Wang K, Wang AX, Mirzat Turhon, Mossa-Basha Mahmud, Michael R. Levitt, David Hasan, Zhu CC. A randomized controlled trial of statins to reduce inflammation in unruptured cerebral aneurysms. JACC. Cardiovascular imaging. JACC. Cardiovascular imaging. 2022 Sep;15(9):1668-1670.
13. Xu Y#, Ren Y#, Li XD, Xu WS, Wang XL, Duan YY, Liu YO, Zhang XH*, Tian DC*. Persistently gadolinium enhancing lesion is predictor of poor prognosis in NMOSD attack: a Clinical Trial. Neurotherapeutics. 2021 Apr;18(2):868-877.
14. Tian DC, Su L, Fan ML, Yang J, Zhang R, Han YJ, Zhang C, Ren HL, Shi KB, Zhu ZL, Dong YH, Fan H, Liu Y, Shi FD*. Bidirectional degeneration in the visual pathway in neuromyelitis optica spectrum disorder(NMOSD). Multiple Sclerosis Journal, 2018 Oct;24(12):1585-1593.
15. Zhu ZL#, Fu Y#, Tian DC, Sun N, Han W, Chang GQ, Dong YH, Xu X, Liu Q, Huang DR，Shi FD*.Combination of the Immune Modulator Fingolimod With Alteplase in Acute Ischemic Stroke: A Pilot Trial. Circulation. 2015; 132(12): 1104-1112.
1. 脑卒中的免疫学研究，天津市自然科学一等奖，
2. 脑和脊髓影像学标志物体系构建及在神经免疫疾病的应用推广，北京市科技进步一等奖，
1. 专利名称：用于 NMOSD 预测或复发监测的生物标志物及其应用（ZL 202110911380.4）
2. 专利名称：一种延长脑梗死溶栓时间窗的的药物和方法（ZL 201711336661.1）
3. 专利名称：一种抑郁情绪电话自动语音识别筛查系统（ZL201110127517.3）
文件上传中...
