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刘圣智，博士，副教授。2018年于哈尔滨医科大学药学院获得博士学位，2015年至2018年于美国普渡大学进行博士联合培养，2018年至2020年于普渡大学从事博士后研究工作。2021年起任首都医科大学药学院药理系副教授，开展教学和研究工作。
主要从事抗肿瘤的机制研究，包括多潜能干细胞治疗肿瘤的机制及其转化研究、合成药物对肿瘤微环境影响的机制研究和抗癌药物研发。作为项目负责人主持国家自然科学基金委 青年基金项目。目前以第一作者或共同通讯作者身份，在包括Bone Research，Cancer Research等杂志上共发表SCI文章7篇，累计影响因子60分，署名发表SCI文章20余篇。
1. Shengzhi Liu*, Xun Sun, Kexin Li, Rongrong Zha, Yan Feng, Tomohiko Sano, Chuanpeng Dong, Yunlong Liu, Uma K Aryal, Akihiro Sudo, Bai-Yan Li, Hiroki Yokota*, Generation of the tumor-suppressive secretome from tumor cells. Theranostics, 2021, 11:8517-8534. IF = 11.6
2. Shengzhi Liu*, Di Wu, Xun Sun, Yao Fan, Rongrong Zha, Aydin Jalali, Yan Feng, Kexin Li, Tomohiko Sano, Nicole Vike, Fangjia Li, Joseph Rispoli, Akihiro Sudo, Jing Liu, Alexander Robling, Harikrishna Nakshatri, Bai-Yan Li, Hiroki Yokota*, Overexpression of Lrp5 enhanced anti-breast cancer effects of osteocytes in the bone. Bone Research, 2021, 9(1):32. IF = 13.362
3. Shengzhi Liu, Di Wu, Xun Sun, Yao Fan, Rongrong Zha, Aydin Jalali, Meghana Teli, Tomohiko Sano, Amanda Siegel, Akihiro Sudo, Mangilal Agarwal, Alexander Robling, Bai-Yan Li, Hiroki Yokota*. Mechanical stimulations can inhibit local and remote tumor progression by downregulating WISP1. FASEB J, 2020, 34(9):12847-12859. IF = 5.834
4. Shengzhi Liu, Yao Fan, Andy Chen, Aydin Jalali, Kazumasa Minami, Kazuhiko Ogawa, Harikrishna Nakshatri, Bai-Yan Li*, Hiroki Yokota*. Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells. Cancer Research, 2018, 78(14):3865-3876. IF = 13.312
5. Shengzhi Liu, Yang Liu, Kazumasa Minami, Andy Chen, Qiaoqiao Wan, Yukun Yin, Liangying Gan, Aihua Xu, Nariaki Matsuura, Masahiko Koizumi, Yunlong Liu, Sungsoo Na, Jiliang Li, Harikrishna Nakshatri, Bai-Yan Li*, Hiroki Yokota*. Inhibiting checkpoint kinase 1 protects bone from bone resorption by mammary tumor in a mouse model. Oncotarget, 2018, 9(10):9364-9378.
6. Yan Feng, Shengzhi Liu, Rongrong Zha, Xun Sun, Kexin Li, Alexander Robling, Baiyan Li, Hiroki Yokota. Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms, Cancers, 2021, 13(2): 267. IF = 6.575
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