1.     国家自然科学基金委员会，面上项目，6257070948，缺血性心脏病“微生物—代谢物”关联机制与机器学习研究，2026-01至2029-12，50万，在研，主持

2.     科技部，国家重点研发计划，2021YFF0501403，心肌纤维化演变与无创精准影像体系构建，2021.12–2026.11，74.4万，在研，课题骨干

3.     北京市科学技术委员会、中关村科技园区管理委员会，Z221100007422038， 99mTc-FAPI显像用于高血压心肌纤维化的临床应用研究，2022-11至2025-11，35万，在研，主持

4.     国家自然科学基金委员会，青年科学基金，81400268，二氯乙酸通过抑制自噬减轻心肌缺血/再灌注损伤的机制研究，2015-01至2017-12，23万，结题，主持

第一作者/通讯作者SCI论文

1.    Wang S, Fu X, Du Z, Liu X, Mai Q, Zhuo L, Xie B,Zou Q. ViruSeg: Harnessing the Power of Large Language-Image Model for EnhancedVirus Image Segmentation. Interdiscip Sci. 2025 Jun 27. doi:10.1007/s12539-025-00711-9. Epub ahead of print.

2.    Liu W, Su Q, Nanna M, Guan X, Ma N, Liu X, Su P, Xie B.Metabolomic Profiling of Coronary and Radial Artery Samples to IdentifyBiomarkers for Coronary Microvascular Dysfunction. FASEB J. 2025;39:e70637.

3.    Su Q, Liu W, Liu X, Su P, Xie B.Bioinformatics-focused identification of metabolomic Markers in coronarymicrovascular disease. Comput Biol Med. 2025;189:109992.

4.    Zhang X, Wang H, Du Z, Zhuo L, Fu X, Cao D, Xie B,Li K. CardiOT: Towards Interpretable Drug Cardiotoxicity Prediction UsingOptimal Transport and Kolmogorov--Arnold Networks. IEEE J Biomed Health Inform.2025;29(3):1759-1770.

5.    He J, Zhang Y, Liu Y, Zhou Z, Li T, Zhang Y, Xie B.BCDB: A dual-branch network based on transformer for predicting transcriptionfactor binding sites. Methods. 2025;234:141-151.

6.    Leng C, Hua C, Lin M, Ding X, Qin Y, Zhang M, Jin S, LiL, Yao S, Xie B, Lu X, Cai Q. Myocardial work by pressure-strain loop isassociated with molecular imaging of fibroblast activation in hypertensivehearts using 99mTc-HFAPI SPECT. Int J Cardiovasc Imaging.2024;40(9):1931-1939.

7.    Li L, Gao J, Liu X, Chen BX, Su P, Xie B.Tissue-level evidence of fibroblast activation protein inhibitor imaging inhypertrophic obstructive cardiomyopathy: a case series. Eur Heart J Case Rep.2024;8(5):ytae189.

8.    Li L, Gao J, Chen BX, Liu X, Shi L, Wang Y, Wang L, WangY, Su P, Yang MF, Xie B. Fibroblast activation protein imaging in atrialfibrillation: a proof-of-concept study. J Nucl Cardiol. 2023;30(6):2712-2720.

9.    Xie B, Li L, Lin M, Nanna M, Su Y, Hua C, Leng C, GanQ, Xi XY, Wang Y, Yao D, Wang L, Yu L, Zhao L, Zhang YP, Dou K, Su P, Lv X, JiaB, Yang MF. 99mTc-HFAPi imaging identifies early myocardial fibrosisin the hypertensive heart. J Hypertens. 2023;41(10):1645-1652.

10.  Xie B, Wang J, Xi XY, Guo X, Chen BX, Li L, Hua C, Zhao S, Su P, Chen M, YangMF. Fibroblast activation protein imaging in reperfused ST-elevation myocardialinfarction: comparison with cardiac magnetic resonance imaging. EuropeanJournal of Nuclear Medicine and Molecular Imaging. 2022;49(8):2786-2797.

11.  An K, Jia Y, Xie B, Gao J, Chen Y, Yuan W, ZhongJ, Su P, Liu X. Alterations in the gut mycobiome with coronary artery diseaseseverity. EBioMedicine. 2024;103:105137.

12.  HuaC, Cai Q, Xi XY, Lin M, Wang L, Li L, Yao D, Liu X, Zhao L, Wang L, Su P, XieB. 99mTc-sestamibi and 18F-fluorodeoxyglucose imagingin patients with cardiogenic shock: A pilot study. Frontiers in CardiovascularMedicine. 2022;9:1047577.

13.  LLi, C Hua, X Liu, Y Wang, L Zhao, Y Zhang, L Wang, P Su, MF Yang, B Xie.SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketonebody—GAPDH malonylation pathway. Journal of Cardiovascular Medicine. 2023;24(4):232-243.

14.  SuY, Chen BX, Wang Y, Li S, Xie B, Yang MF. Association of atrial 18F-fluorodeoxyglucoseuptake and prior ischemic stroke in non-atrial fibrillation patients. Journalof Nuclear Cardiology. 2022;29(6):3194-3203.

15.  Xie B,Chen BX, Nanna M, Wu JY, Zhou Y, Shi L, Wang Y, Zeng L, Wang Y, Yang X, Liu X,Yang MF. 18F-fluorodeoxyglucose positron emissiontomography/computed tomography imaging in atrial fibrillation: a pilotprospective study. European Heart Journal-Cardiovascular Imaging.2021;23(1):102-112.

16.  BXChen, B Xie, Y Zhou, L Shi, Y Wang,L Zeng, X Liu, MF Yang. Association of Serum Biomarkers and CardiacInflammation in Patients With Atrial Fibrillation: Identification by PositronEmission Tomography. Frontiers in Cardiovascular Medicine. 2021;8:735082.

17.  B Xie, BX Chen, JY Wu, X Liu, MF Yang. Factorsrelevant to atrial 18F-fluorodeoxyglucose uptake in atrial fibrillation.Journal of Nuclear Cardiology. 2020;27(5):1501-1512.

18.  SLi, B Xie, W Zhang, T Li.Dichloroacetate ameliorates myocardial ischemia-reperfusion injury viaregulating autophagy and glucose homeostasis. Archives of Medical Science.2019; 15 (1). doi.org/10.5114/aoms.2019.87503.

19.  WQZhang, BQ Xie. A meta-analysis ofthe relations between blood microRNA-208b detection and acute myocardialinfarction. European Review for Medical and Pharmacological Sciences. 2017; 21(4): 848-854.

20.  HSun, Y Tian, L Zheng, Q Pan, B Xie.Electrocardiographic profile of adenosine pharmacological stress testing.Experimental and therapeutic medicine. 2015; 9 (4): 1178-1184.

21.  KFDou, BQ Xie, XJ Gao, Y Li, YJ Yang,ZX He, MF Yang. Use of resting myocardial 18F-FDG imaging in thedetection of unstable angina. Nuclear medicine communications. 2015; 36 (10):999-1006.

22.  BQ Xie, W Wang, WQ Zhang, XH Guo, MF Yang, L Wang,ZX He, YQ Tian. Ventilation/perfusion scintigraphy in children withpost-infectious bronchiolitis obliterans: a pilot study. PloS one. 2014; 9(5):e98381.

23.  Xie BQ, Tian YQ, Zhang J,Zhao SH, Yang MF, Guo F, Wang DY, Wei HX, Chu KW, He ZX. Evaluation of left andright ventricular ejection fraction and volumes from gated blood-pool SPECT inpatients with dilated cardiomyopathy: comparison with cardiac MRI. Journal ofNuclear Medicine. 2012; 53(4):584-591.

24.  MFYang, BQ Xie, XD Lv, ZD Hua, FJDuan, CW Yan, G Xu, LP Song. The role of myocardial viability assessed byperfusion/F-18 FDG imaging in children with anomalous origin of the leftcoronary artery from the pulmonary artery. Clinical Nuclear Medicine. 2012; 37(1), 44-48.

已授权的发明专利

1.     谢博洽;刘文婷;苏丕雄;张文谦;苏晴；冠状动脉微血管疾病相关的生物标志物及其应用，2024-11-15，中国，ZL202411635449.5

2.     谢博洽;刘文婷;苏丕雄;张文谦;苏晴；冠状动脉微血管疾病相关的生物标志物及其应用，2024-11-15，中国，ZL202411635454.6

3.     谢博洽;李丽娜;苏丕雄;杨敏福;刘兴鹏;高杰;郭玉林;张文谦;刘晓艳;赵蕾;张叶萍;王怡丹;华存存;房颤相关的生物标志物及其应用,2023-07-21,中国,ZL202310904029.1

4.     谢博洽;刘晓艳;苏丕雄;袁雯;高杰;张文谦;张叶萍;贾彦雄;杨敏福;王丽;一种血浆外泌体circRNA标志物及其应用,2022-06-07,中国,ZL202210028321.7

5.     刘晓艳;刘昕明;王乐丰;陈牧雷;袁雯;谢博洽;钟久昌;陈艺航;安坤;张叶萍;心绞痛相关的标志物及其应用,2022-08-02,中国,ZL202210027558.3

获奖

2022年度 美国核心脏协会年度最佳临床研究奖

2024年度 美国核心脏协会AmiIskandrian奖

国际会议受邀发言

2022年第 62 届日本核医学会年会特邀报告：FDGimaging in non-ischemic heart disease

2024 年美国心脏病学会年会（ACC）口头发言：Investigatingepicardial adipose tissue proteins aspotential biomarkers in atrialfibrillation

2025年欧洲心脏病学会年会（ESC）口头发言：Metabolomicprofiling of coronary and radial artery samples to identify biomarkers forcoronary microvascular dysfunction

2025年欧洲心脏病学会年会（ESC）口头发言：Gutviral dysbiosis as a contributor to acute myocardial infarction: insights intovirome-bacteria-metabolite interactions

2025年美国核心脏病学年会（ASCN）年度最佳临床研究特邀报告：99mTc-HFAPiSPECT imaging predicts left ventricular remodeling after acute myocardialinfarction