个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
教育背景与工作经历：
1999.08 ~ 2003.07：北京师范大学 数学系 数学与应用数学专业，2003年获理学学士学位
2003.08 ~ 2008.07：中国协和医科大学 基础医学研究所 生物化学与分子生物学系，2008年获理学博士学位
2008.07 ~ 2011.11：上海交通大学医学院附属瑞金医院 医学基因组学国家重点实验室，助理研究员
2011.11 ~ 2017.06：上海交通大学医学院附属瑞金医院 医学基因组学国家重点实验室，副研究员
2014.06 ~ 2015.06：美国德克萨斯大学 MD安德森癌症中心 流行病学系，访问学者
2017.06 ~ 2023.04：中日友好医院 临床医学研究所 生物样本平台，主任，副研究员
2023.05 ~ 至今：首都儿科研究所 循证医学中心，研究员
论文发表：
自2007年，以第一作者和通讯作者在SCI收录杂志发表论著、综述、评论和通信类型论文逾230篇
社会兼职和经历：
Frontiers in Public Health和Frontiers in Pediatrics杂志副主编（2021年7月至今）
iLiver杂志青年编委（2022年7月至今）
2021年12月担任北京市朝阳区九三学社医药卫生委员会副主任，任期五年
本科生和研究生课程：
2022-2025，独立承担北京协和医学院研究生课程《临床大数据与人工智能》。
2019-2025，参与承担北京中医药大学2019级卓越班《临床科研思路与方法》课程“循证医学与系统综述概述”与“临床研究证据的严格评价及报告标准”内容
获奖：
2023年9月，妇幼健康科学技术奖-科技成果奖, 省部二等奖；儿童生长发育偏离早期筛查评估和精准诊断体系的建立；中国妇幼健康研究会；牛文全 (排名6/14)
学术影响：
2020和2025年成为中国儿科最近1年发表的论文中最有影响力的学者（Hanson临床科研 公众号：哪个医院儿科发SCI论文最多？大数据分析揭开谜底）
自2009年，相继主持国家自然科学基金面上项目、国家自然科学基金青年项目、首都卫生发展科研专项-自主创新项目、北京协和医学院“中央高校基本科研业务费”项目、上海市青年科技启明星A类计划、上海市自然科学基金、上海市晨光计划等15项课题。
2021
1. Mengyang He, Xiangling Deng, WenquanNiu (Corresponding author). Concerns over Physicians’Electrocardiogram Interpretations. JAMA Internal Medicine. 2021; 181(5):721-722.doi: 10.1001/jamainternmed.2020.8605
2. Yehong Tian, Xiaowei Qiu,Chengxiang Wang, Jianxin Zhao, Xin Jiang, Wenquan Niu (Corresponding author),Jinchang Huang, Fengyu Zhang. Cancer associates with risk and severe events ofCOVID-19: A systematic review and meta-analysis. International Journal of Cancer.2021; 148(2):363-374.
3. Liang Ma, Shaoting Wang, HailingZhao, Meijie Yu, Xiangling Deng, Yongwei Jiang, Yongtong Cao, Ping Li, WenquanNiu (Corresponding author). Susceptibility of ApoB and PCSK9genetic polymorphisms to diabetic kidney disease among Chinese diabeticpatients. Frontiers in Medicine. 2021; 8:659188. doi:10.3389/fmed.2021.659188.
4. XianglingDeng, Min Yang, Shunan Wang, Qiong Wang, Bo Pang, Kundi Wang, Zhixin Zhang, WenquanNiu (Corresponding author). Factors Associated withChildhood Asthma and Wheeze in Chinese Preschool-Aged Children. Frontiersin Medicine. 2021; 8:742581. doi: 10.3389/fmed.2021.742581.
5. Xiangling Deng, Mengyang He,Danni He, Yuqing Zhu, Zhixin Zhang, Wenquan Niu (Corresponding author).Sleep Duration and Obesity in Children and Adolescents: Evidence from anUpdated and Dose-Response Meta-Analysis. Sleep Medicine. 2021; 78:169-181.doi: 10.1016/j.sleep.2020.12.027.
6. Min Yang,Xiangling Deng, Shunan Wang, Kundi Wang, Wenquan Niu (Corresponding author),Zhixin Zhang. Risk factors for allergic diseases: a cross-sectional survey of 9,501Chinese preschool-aged children. Translational Pediatrics. 2021;10(8):1989-2005.
7. Bo Zhou, Yuan Yuan, Shunan Wang,Zhixin Zhang, Min Yang, Xiangling Deng, Wenquan Niu (Corresponding author).Risk profiles of severe illness in children with COVID-19: a meta-analysis ofindividual patients. Pediatric Research. 2021;90(2):347-352.
8. Yuan Yuan, Bo Zhou, Shufang Liu,Yunfeng Wang, Kundi Wang, Zhixin Zhang, Wenquan Niu (Corresponding author).Meta-analysis of Metabolic Changes in Children with Idiopathic Growth HormoneDeficiency after Recombinant Human Growth Hormone Replacement Therapy. Endocrine.2021; 71(1):35-46.
9. Yuan Yuan, Bo Zhou, Kundi Wang,Yunfeng Wang, Zhixin Zhang, Wenquan Niu (Corresponding author).Identification of Contributing Predictors for Short Stature and Pre-shortnessamong 7310 Chinese Preschool-Aged Children. Endocrine. 2021;71(2):443-452.
10. Luyao Huan, Xiangling Deng,Mengyang He, Shunhong Chen, Wenquan Niu (Corresponding author).Meta-Analysis: Early Age at Natural Menopause and Risk for All-Cause andCardiovascular Mortality. BioMed Research International. 2021;2021:6636856. doi: 10.1155/2021/6636856.
11. Min Yang, Xiangling Deng, ShunanWang, Bo Zhou, Wenquan Niu (Corresponding author), Zhixin Zhang.Identification and Characterization of Factors Associated with Short Statureand Pre-Shortness in Chinese Preschool-Aged Children. Endocrine Connections.2021; 10(6):607-619.
12. Jialin Li, Danni He, WenjingZhao, Xi’ai Wu, Minjing Luo, Ying Wang, Meihua Yan, Wenquan Niu (Correspondingauthor), Ping Li. Association of Mineral Metabolism Biomarkers withChronic Kidney Disease in Chinese Adults. Clinical and Experimental Nephrology.2021; 25(7):760-770.
2022
1. Zhang J, Liang C, Niu W(Correspondingauthor). Survivorship after neoadjuvant chemotherapy. The Lancet Oncology. 2022; 23(3):e95. doi: 10.1016/S1470-2045(22)00011-0.
2. Zhang J, Liang C, Niu W(Correspondingauthor). The evidence gap between alcohol consumption andoesophageal squamous cell carcinoma in east Africa. The Lancet Global Health.2022; 10(5):e622. doi: 10.1016/S2214-109X(22)00090-0.
3. Li C, Niu W (Correspondingauthor). NT-proBNP in Early Pregnancy and Future Hypertension—MoreExplorations Needed. JAMA Cardiology. 2022; 7(9):989. doi: 10.1001/jamacardio.2022.2000.
4. Sun P, Yang H, Niu W(Correspondingauthor). Concerns over Thyroid Cancer Surgeries and Quality ofLife. JAMA Surgery. 2022; 157(8):739-740. doi:10.1001/jamasurg.2022.0813.
5. Wang L, Niu W (Correspondingauthor). More Explorations Needed to Assess Matrix Metalloproteinase7 Expression When Predicting the Pathologic Response to Neoadjuvant Therapy forPancreatic Ductal Adenocarcinoma. JAMA Surgery. 2022; 158(1):102-103. doi:10.1001/jamasurg.2022.4975.
6. Sun Y, Niu W (Correspondingauthor), Yang Z. Hidden-mortality risk among patients deemed “low-risk”following high-risk operations. Hepatobiliary Surgery and Nutrition.2022; 11(2):311-313.
7. Pang B, Wang Q, Yang M, Xue M,Zhang Y, Deng X, Zhang Z, Niu W (Corresponding author). Identification andoptimization of contributing factors for precocious puberty by machine/deeplearning methods in Chinese girls aged 6-16 years. Frontiers in Endocrinology.2022; 13:892005. doi: 10.3389/fendo.2022.892005.
8. Wang Q, Yang M, Deng X, Wang S,Zhou B, Li X, Shi J, Zhang Z, Niu W (Corresponding author).Explorations on risk profiles for overweight and obesity in 9501 preschool-agedchildren. Obesity Research & Clinical Practice. 2022; 16(2):106-114.
9. Deng X, Yang M, Wang S, Zhou B,Wang K, Zhang Z, Niu W (Corresponding author).Identification and Characterization of Influential Factors in Susceptibility toAttention Deficit Hyperactivity Disorder among Preschool-Aged Children. Frontiersin Neuroscience. 2022; 15:709374. doi: 10.3389/fnins.2021.709374.
10. Hui Q, Hao Y, Ye F, Pang B, Niu W(Correspondingauthor), Zhang Q. Genetically highangiotensin-converting enzyme concentrations causally increase asthma risk: Ameta-analysis using Mendelian randomization. Frontiers in Medicine.2022; 9:941944. doi: 10.3389/fmed.2022.941944.
11. Yang M, Pang B, Wang Q, Zhang Z,NiuW(Corresponding author). The causal association between geneticallyregulated 25OHD and chronic obstructive pulmonary disease: A meta-analysisusing Mendelian randomization. Frontiers in Genetics. 2022; 13:932764. doi: 10.3389/fgene.2022.932764.
12. Zhang X, Hu D, Deng X, Lin J,Zheng X, Peng F, Meng F, Niu W (Corresponding author). Prediction of presurgicalmetabolic syndrome for gastric cancer-specific mortality is more evident insmokers: the FIESTA study. CancerMedicine. 2022; doi: 10.1002/cam4.5116.
13. Zhou B, Liu S, Wang J, Zhang T,Yuan Y, Niu W (Corresponding author), ZhangZ, Wang L. A meta-analysis of combination therapy with gonadotrophin-releasinghormone agonist and growth hormone for children with idiopathic short statureand normal timed puberty. Endocrine. 2022; 75(3):698-708.
14. Wang Q, Yang M, Pang B, Xue M,Zhang Y, Zhang Z, Niu W (Corresponding author). Predicting risk ofoverweight or obesity in Chinese preschool-aged children using artificialintelligence techniques. Endocrine. 2022; doi:10.1007/s12020-022-03072-1.
15. Zhang Z, Zhang X, Niu W(Corresponding author), Yuan Y. Association between pituitaryheight and growth response to recombinant human growth hormone in prepubertalchildren with growth hormone deficiency. Endocrine. 2022; doi:10.1007/s12020-022-03217-2.
16. Hao Y, Zhou Q, Sun Y, Niu W(Correspondingauthor), Du J. Association of three single nucleotide polymorphismsin interleukin 6 gene with risk of chronic obstructive pulmonary disease. GENE.2022; 828:146467. doi: 10.1016/j.gene.2022.146467.
17. He D, Li N, Lu X, Li W, Chen Y,Sun Z, Zhang L, Guo L, Cui X, Song G, Niu W (Corresponding author),Zhang Q. Association of mitochondrial respiratory chain enzymes with the riskand mortality of sepsis among Chinese children. BMC Infectious Diseases.2022; 22(1):34. doi: 10.1186/s12879-021-07014-6.
18. He M, Deng X, Wang X, Wan Y, HuangJ, Zhang Z, Niu W (Corresponding author). Association betweenRecombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk inChildhood: Systematic Review and Meta-Analysis. Frontiers in Pediatrics. 2022; 10:866295. doi:10.3389/fped.2022.866295.
19. Xue M, Wang Q, Zhang Y, Pang B,Yang M, Deng X, Zhang Z, Niu W (Corresponding author).Factors Associated with Lower Respiratory Tract Infection among ChineseStudents Aged 6-14 Years. Frontiers in Pediatrics. 2022;10:911591. doi: 10.3389/fped.2022.911591.
20. Zhang Y, Wang Q, Xue M, Pang B,Yang M, Deng X, Zhang Z, Niu W (Corresponding author).Identifying factors associated with central obesity in school students usingartificial intelligence techniques. Frontiers in Pediatrics.2022; 10:1060270. doi: 10.3389/fped.2022.1060270.
21. Deng X, He M, Zhang J, Huang J,Luo M, Zhang Z, Niu W (Corresponding author).SARS-CoV-Related Pandemic Outbreaks and Mental Disorder Risk. Journalof Nervous and Mental Disease. 2022; 210(12):900-911. doi:10.1097/NMD.0000000000001543.
2023
1. Xiaoqian Zhang, Zhixin Zhang, Wenquan Niu (Corresponding author).Lower respiratory tract infections in early childhood. Lancet.2023; 402(10418):2193-2194. doi: 10.1016/S0140-6736(23)01621-5.
2. Xiaoqian Zhang, Zhixin Zhang, Wenquan Niu (Corresponding author).Concerns About a Frailty Screening Initiative and Postoperative Mortality. JAMASurgery. 2023; doi: 10.1001/jamasurg.2023.2857.
3. Xiaoqian Zhang, Qiong Wang, ZiyuGao, Zifeng Zhang, Jing Wu, Zhixin Zhang, Wenquan Niu (Corresponding author).Prevalence of malnutrition and its associated factors among 18,503 Chinesechildren aged 3-14 years. Frontiers in Nutrition. 2023;10:1228799. doi: 10.3389/fnut.2023.1228799.
4. Zihuan Zhang, Duo Li, TianxiaoWang, Heyuan Niu, Wenquan Niu (Corresponding author), Zhiying Yang. Pancreaticadenocarcinoma at stage II after endovascular repair for abdominal aorticaneurysm: a case report and literature review. Journal of Clinical Medicine.2023; 12(2):443.
5. Jia-Lin Li, Zhen Cai, Jing Zhao,Xiang-Gang Zhu, Qian Li, Yan-Shuang Li, Meng-Chao Liu, Fang-Qiang Cui, Wen-JingZhao, Wen-Quan Niu (Corresponding author).Association between anemia-related biomarkers and the adequacy of peritonealdialysis in Chinese patients with chronic kidney disease. Frontiers inPhysiology. 2023; 14:1170537.
6. Hao Y, Dong M, Sun Y, Duan X,Niu W. Effectiveness and safety of monoclonal antibodies against amyloid-betavis-à-vis placebo in mild or moderate Alzheimer’s disease. Frontiers inNeurology. 2023; 14:1147757.
7. Liu MC, Li JL, Wang YF, Meng Y,Cai Z, Shen C, Wang MD, Zhao WJ, Niu WQ (Corresponding author). Association between thyroidhormones and diabetic kidney disease in Chinese adults. BMC EndocrineDisorders. 2023; 23(1):56.
2024
1. Zheng F, Chen K, Niu W (Corresponding author). Primary ovarian insufficiency prediction in adultsurvivors of childhood cancer: model concerns. Lancet Oncol. 2024; 25(2):e58. doi:10.1016/s1470-2045(23)00650-2.
2. Ma N, Cui X, Niu W (Corresponding author). Vitamin D supplements and future fracture riskamong Mongolian schoolchildren. Lancet Diabetes Endocrinol. 2024; 12(5):300.doi:10.1016/s2213-8587(24)00061-5.
3. Bai X, Cui X, Niu W (Corresponding author). Unplanned Hospitalization Prediction DuringChemoradiotherapy Via Machine Learning Classifiers. JAMA Oncol. 2024; 10(10):1442. doi:10.1001/jamaoncol.2024.3620.
4. Chen K, Zheng F, Niu W (Corresponding author). Robotic Technology in Emergency General Surgery. JAMA Surg. 2024; 159(9):1091-1092. doi:10.1001/jamasurg.2024.2115.
5. Zheng F, Chen K, Niu W (Corresponding author). Concerns Over Prediction of Kidney Discard andNonrecovery. JAMA Surg. 2024; 159(6):720. doi:10.1001/jamasurg.2024.0207.
6. Zhang X, Ma N, Lin Q, Chen K, Zheng F, Wu J, DongX, Niu W (Corresponding author). Body Roundness Index and All-Cause Mortality AmongUS Adults. JAMA Netw Open. 2024; 7(6):e2415051.doi:10.1001/jamanetworkopen.2024.15051.
7. Li D, Xu L, Deng X, Sun Y, Zhang Z, Wang T, Wei R,Luo Y, Niu W (Corresponding author), Yang Z. Laparoscopic versus open surgery intreating patients with gallbladder cancer: a systematic review andmeta-analysis. Hepatobiliary Surg Nutr. 2024; 13(3):444-459. doi:10.21037/hbsn-22-597.
8. Bai X, Zhang L, Ji X, Chen K, Di X, Zheng F, Bai P,Niu W (Corresponding author). Long-term weight change, incident cardiovasculardisease and all-cause mortality among diabetic adults. Diabetes Res Clin Pract.2024; 219:111946. doi: 10.1016/j.diabres.2024.111946.
9. Ma N, Ji X, Shi Y, Wang Q, Wu J, Cui X, Niu W (Corresponding author). Adverse childhood experiences and mental healthdisorder in China: A nationwide study from CHARLS. J Affect Disord. 2024; 355:22-30. doi:10.1016/j.jad.2024.03.110.
10. Meng Y, Ma N, Shi Y, Zhang N, Wu J, Cui X, Niu W (Corresponding author). The association of physical activity andsedentary behavior with depression in US adults: NHANES 2007-2018. Front Public Health. 2024; 12:1404407. doi:10.3389/fpubh.2024.1404407.
11. Wang Q, Wu J, Dong X, Niu W (Corresponding author). Trends in urine lead and associated mortality inUS adults: NHANES 1999-2018. Front Nutr. 2024; 11:1411206. doi:10.3389/fnut.2024.1411206.
12. Zhang X, Xue M, Zhang Z, Gao Z, Li C, Wu J, Niu W (Corresponding author). Impact of social, familial and personal factorson depressive symptoms in middle-aged and older adults from the national CHARLScohort. BMC Public Health. 2024; 24(1):2669. doi:10.1186/s12889-024-20159-8.
13. Li C, Zhou F, Wu J, Fu D, Li X, Niu W (Corresponding author). Iron metabolism biomarkers and mortality risk inU.S. patients with congestive heart failure: NHANES 1999-2018 analysis. Nutr Metab Cardiovasc Dis. 2024; 34(10):2325-2333.doi:10.1016/j.numecd.2024.05.027.
14. Wu J, Zhang X, Wang Q, Ma N, Zheng F, Chen K, Niu W(Corresponding author). Perfluoroalkyl substances and metabolic syndrome:A cross-sectional study using data from the US national health and nutritionexamination survey. Heliyon. 2024; 10(17):e36894.doi:10.1016/j.heliyon.2024.e36894.
15. Wu J, Zheng F, Chen K, Dong X, Niu W (Corresponding author). Composite dietary antioxidant index, chronicrespiratory disease, and all-cause mortality: National Health and NutritionExamination Survey, 2003-2018. Eur J Nutr. 2024; 64(1):19. doi: 10.1007/s00394-024-03508-6.
16. Xue M, Wang Q, Pang B, Zhang X, Zhang Y, Deng X,Zhang Z, Niu W (Corresponding author). Association Between Circulating Zinc and Risk forChildhood Asthma and Wheezing: A Meta-analysis on 21 Articles and 2205Children. Biol Trace Elem Res. 2024; 202(2):442-453. doi:10.1007/s12011-023-03690-4.
17. Wang Q, Pang B, Wu J, Li C, Niu W (Corresponding author). Reproductive factors and cardiometabolic diseaseamong middle-aged and older women: a nationwide study from CHARLS. Front Cardiovasc Med. 2024; 11:1345186. doi:10.3389/fcvm.2024.1345186.
18. Chen Z, Qiu X, Wang Q, Wu J, Li M, Niu W (Corresponding author). Serum vitamin D and obesity among US adolescents,NHANES 2011-2018. Front Pediatr. 2024; 12:1334139. doi:10.3389/fped.2024.1334139.
19. Feng Z, Wei Y, Wang Y, Liu C, Qu D, Li J, Ma L, NiuW (Corresponding author). Development of a prediction nomogram for 1-monthmortality in neonates with congenital diaphragmatic hernia. BMC Surg. 2024; 24(1):198. doi:10.1186/s12893-024-02479-z.
20. Zhou B, Qu X, Li M, Wang X, Xu Q, Wang J, Liu X,Zhang L, Zhang T, Gu J, Zhou L, Peng N, Niu W (Corresponding author), Wang L. Correlation of bone age development with overweight and obesityin 23,305 children from Beijing. Endocrine. 2024; doi:10.1007/s12020-024-03988-w.
2025
1. Wu J, Dong WH, Zheng F, Chen K, Ke Y, Niu W (Corresponding author). Dietary carotenoids and acute respiratory infection in the general USpopulation: NHANES 2003 - 2018. BMC Pediatr. 2025 Oct 20;25(1):823.
2. Xue M, Zhang Z, Niu W (Corresponding author). Assessing the impact of radiofrequency ablation on hilarcholangiocarcinoma: a systematic review and meta-analysis. Int J Surg. 2025 Oct14. doi: 10.1097/JS9.0000000000003649.
3. Zhou B, Qu X, Wang J, Xu Q, Zhang L, Wang X, PengN, Gu J, Zhang X, Wang Q, Niu W (Corresponding author), Wang L. Metabolic changes in children withidiopathic central precocious puberty after gonadotrophin-releasing hormoneagonist therapy: a meta-analysis. Front Pediatr. 2025 Aug 29;13:1519746. doi:10.3389/fped.2025.1519746.
4. Zheng F, Chen K, Zhang X, Wang Q, Zhang Z, Niu W (Corresponding author). Prevalence of malnutrition and associated factorsin Chinese children and adolescents aged 3-14 years using machine learningalgorithms. J Glob Health. 2025 Jul 21;15:04204. doi: 10.7189/jogh.15.04204.
5. Xue M, Shen M, Wang S, Pang B, Zhang X, Chen K,Zhang Z, Niu W (Corresponding author). Factors associated with psycho-behavioralproblems among 100 children with phenylketonuria aged 6-18 years. Orphanet JRare Dis. 2025 Jun 11;20(1):297. doi: 10.1186/s13023-025-03824-y.
6. Zhu J, Kang M, Xu Y, Zhang D, Yue T, Li M, Wen M,Wu F, Su G, Yang Y, Niu W (Corresponding author), Lai J. Clinical characteristics and treatment ofinfantile Takayasu arteritis in the Chinese Han population: a single-centerstudy. Pediatr Rheumatol Online J. 2025 Jun 10;23(1):64. doi:10.1186/s12969-025-01111-5.
7. Wang Q, Zhang Z, Niu W (Corresponding author). Age and Sex Differences in Treatment Efficacy forType 2 Diabetes. JAMA. 2025 Jul 8;334(2):178-179. doi: 10.1001/jama.2025.4413.
8. Xue M, Zhang X, Chen K, Zheng F, Wang B, Lin Q,Zhang Z, Dong X, Niu W (Corresponding author). Visceral adiposity index, premature mortality,and life expectancy in US adults. Lipids Health Dis. 2025 Apr 15;24(1):139.doi: 10.1186/s12944-025-02560-3.
9. Wang Q, Yang M, Chen K, Zheng F, Zhang Z, Niu W (Corresponding author). Clustering unhealthy lifestyle factors in Chinesechildren and adolescents with overweight or obesity. BMC Pediatr. 2025 Mar24;25(1):226.
10. Zhou B, Xu Q, Li S, Wang J, Liu J, Zhang T, Qu X,Wang X, Zhang L, Liu X, Gu J, Zhou L, Chen F, Zong X, Niu W (Corresponding author), Wang L. Impact of Omicron infection on childhoodhealth: the Beijing long-COVID study. Front Public Health. 2025 Feb 19;13:1377745.
11. Chen K, Zheng F, Zhang X, Wang Q, Zhang Z, Niu W (Corresponding author). Factors associated with underweight, overweight,and obesity in Chinese children aged 3-14 years using ensemble learningalgorithms. J Glob Health. 2025 Feb 7;15:04013.
12. Bai X, Zhang L, Ji X, Chen K, Di X, Zheng F, Bai P,Niu W (Correspondingauthor). Long-term weight change, incident cardiovascular disease and all-causemortality among diabetic adults. Diabetes Res Clin Pract. 2025 Jan;219:111946.
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