个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
研究员 教授 博士生导师
主要从事微生物检测技术、微生物-宿主相互作用等方面的研究。
担任国家动物布鲁氏菌病参考实验室学术委员会委员、中国微生物学会微生物生物安全专业委员会青年委员、中国微生物学会感染与免疫专业委员会细菌学组青年委员、中国医疗保健国际交流促进会分子诊断学分会委员。荣获省部级科技进步奖2项,多次获得国家自然科学基金、国家重点压研发计划、国家重大传染病专项、军委科技委基础加强计划等课题资助,发表SCI文章60余篇。
(1) 北京市自然科学基金重点项目“呼吸道合胞病毒疫苗有效成分检测及关键质量评价体系研究”,2024-2026,100万,负责人;
(2) 首都卫生发展科研专项项目“儿童下呼吸道病原靶向测序检测的临床应用研究”,2024-2026,100万,负责人;
(3) 国家自然科学基金青年面上项目“布鲁氏菌毒力蛋白Btp1/TcpB抑制宿主天然免疫信号通路机制研究”,2014-2016,23万,负责人;
(4) 国家自然科学基金面上项目““效应蛋白BPE005促进布鲁氏菌胞内生存的功能和作用机制研究”,2016-2019,50万,负责人;
(5) 全军医学科技青年拔尖项目“基于CPA-微流控芯片的病原体POCT系统研究”,2013-2017,25万,负责人。
1: Min Z, Xie J, Xiao M, Li J, Peng X, Liu S, He J, Lin W, Li X, Ke Y, Chen Q. A DNA Triangular Prism-Based Multitargeting Transistor for Ultrasensitive Detection of Respiratory Virus. Anal Chem. 2025 Sep 30;97(38):20850-20858. doi:10.1021/acs.analchem.5c02952IF: 6.7 Q1
2: Jiang B, Wang Z, Wang M, Wang S, Li M, Meng Z, Yuan J, Ke Y. Safety Assessment of Two Human Fecal Bacteroides Strain Isolates in Immunodeficient Mice. Probiotics Antimicrob Proteins. 2025 Apr 1.doi:10.1007/s12602-025-10529-yIF: 4.4 Q1
3: Yuan L, Lin W, Cao Y, Lv J, Chao S, Liu Y, Ma J, Guo J, Ke Y, Wang L, Tie J. Disinfection efficacy of peroxyacetic acid against bacterial spores. J Hazard Mater. 2025 Apr 5;487:137128.doi:10.1016/j.jhazmat.2025.137128IF: 11.3 Q1
4: Cui J, Xu Z, Yu Z, Zhang Q, Liu S, Du B, Gan L, Yan C, Xue G, Feng J, Fan Z, Fu T, Feng Y, Zhao H, Ding Z, Li X, Zhang R, Cui X, Tian Z,Huang K, Wang W, Bai Y, Zhou H, Sun Y, Yang X, Wan M, Ke Y, Yuan J. High-alcohol-producing Klebsiella pneumoniae aggravates lung injury by affecting neutrophils and theairway epithelium. Cell Rep Med. 2025 Jan 21;6(1):101886.doi:10.1016/j.xcrm.2024.101886IF: 10.6 Q1
5: Liang Y, Xiao M, Xie J, Li J, Zhang Y, Liu H, Zhang Y, He J,Zhang G, Wei N, Peng LM, Ke Y, Zhang ZY. Amplification-Free Detection of SARS-CoV-2 Down to Single Virus Level by Portable Carbon Nanotube Biosensors. Small. 2023 Aug;19(34):e2208198. doi:10.1002/smll.202208198IF: 12.1 Q1
6: Zhao Y, Wang T, Liu Z, Ke Y, Li R, Chen H, You Y, Wu G, Cao S,Du Z, Bai F, Yang R. Single-cell transcriptomics of immune cells in lymph nodes reveals their composition and alterations in functional dynamics during theearly stages of bubonic plague. Sci China Life Sci. 2023 Jan;66(1):110-126.doi:10.1007/s11427-021-2119-5IF: 9.5 Q1
7: Wan L, Gao Q, Deng Y, Ke Y, Ma E, Yang H, Lin H, Li H, Yang Y,Gong J, Li J, Xu Y, Liu J, Li J, Liu J, Zhang X, Huang L, Feng J, Zhang Y, Huang H, Wang H, Wang C, Chen Q, Huang X, Ye Q, Li D, Yan Q, Liu M, Wei M, MoY, Li D, Tang K, Lin C, Zheng F, Xu L, Cheng G, Wang P, Yang X, Wu F, Sun Z,Qin C, Wei C, Zhong H. GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia. Nat Metab. 2022 Jan;4(1):29-43.doi:10.1038/s42255-021-00508-2IF: 20.8 Q1
8: Li Y, Ke Y, Xia X, Wang Y, Cheng F, Liu X, Jin X, Li B, XieC, Liu S, Chen W, Yang C, Niu Y, Jia R, Chen Y, Liu X, Wang Z, Zheng F, Jin Y,Li Z, Yang N, Cao P, Chen H, Ping J, He F, Wang C, Zhou G. Genome-wide association study of COVID-19 severity among the Chinese population. Cell Discov. 2021 Aug 31;7(1):76. doi:10.1038/s41421-021-00318-6IF: 12.5 Q1
9: Pu Y, Ke Y, Bai F. Active efflux in dormant bacterial cells -New insights into antibiotic persistence. Drug Resist Updat. 2017 Jan;30:7-14. doi:10.1016/j.drup.2016.11.002IF: 21.7 Q1
10: Chen Z, Liang H, Chen X, Ke Y, Zhou Z, Yang M, Zen K, YangR, Liu C, Zhang CY. An Ebola virus-encoded microRNA-like fragment serves as a biomarker for early diagnosis of Ebola virus disease. Cell Res. 2016 Mar;26(3):380-3. doi:10.1038/cr.2016.21IF: 25.9 Q1
11: Ke Y, Wang Y, Liu S, Guo J, Zhang W, Yuan X, Zhang N, WangZ, Song H, Huang L, Chen Z. High severity and fatality of human infections withavian influenza A(H7N9) infection in China. Clin Infect Dis. 2013 Nov;57(10):1506-7. doi:10.1093/cid/cit371IF: 7.3 Q1
12: Ke Y, Wang Y, Zhang W, Huang L, Chen Z. Deaths associated with avian influenza A(H7N9) virus in China. Ann Intern Med. 2013 Jul 16;159(2):159-60. doi:10.7326/0003-4819-159-2-201307160-00669IF: 15.2 Q1
13: Ke Y, Chen Z, Yang R. Yersinia pestis: mechanisms of entry into and resistance to the host cell. Front Cell Infect Microbiol. 2013 Dec 24;3:106. doi:10.3389/fcimb.2013.00106IF: 4.8 Q1
14: Ke Y, Wang Y, Li W, Chen Z. Type IV secretion system of Brucella spp. and its effectors. Front Cell Infect Microbiol. 2015 Oct 13;5:72.doi:10.3389/fcimb.2015.00072IF: 4.8 Q1

文件上传中...