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王国鹏,男,首都医科大学附属北京友谊医院耳鼻咽喉头颈外科中心副主任。医学博士,美国Michigan大学博士后,主任医师,副教授,硕士研究生导师。中华医学会耳鼻咽喉-头颈外科分会青年委员、 中国中西医结合耳鼻咽喉科专业委员会耳聋防治专家委员会副主任委员、中国医师协会耳鼻咽喉头颈外科分会听力学组委员、中国生物物理学会听觉言语和交流分会委员、《中华耳科学》杂志和《听力学与言语疾病杂志》编委、《中华耳鼻咽喉头颈外科杂志》通讯编委。主要从事耳鼻咽喉头颈外科临床和研究工作,擅长耳显微手术、耳内镜手术、人工耳蜗植入、眩晕和面瘫的外科治疗等。主持国家自然科学基金3项,省部级课题2项,入选北京市医管中心“青苗人才”计划;发表SCI收录论文20余篇,4篇被选为杂志封面;参与编写《耳鼻咽喉头颈外科学》教材2部,获批专利2项。曾获“北京优秀医师”,首都医科大学教育教学一等奖。

1. 国家自然科学基金面上项目,82371139,双AAV载体介导APG和Espin1共同过表达促进成年小鼠前庭毛细胞功能性再生及机制研究,2024.01-2027.12,49万元,负责人
2. 北京市通州区科技计划项目,KJ2024CX057,基于四维血流磁共振成像和CT血管造影的搏动性耳鸣血流动力学评估和乙状窦骨壁重建术的优化,2024.01-2025.12,10万元,负责人
3. 西藏自治区自然科学基金组团式医学援藏项目,XZ2024ZR-ZY035(Z),基于宏基因组捕获法的西藏地区慢性化脓性中耳炎病原谱与耐药性分析,2024.06-2026.06,14.85万元,负责人
4. 北京市自然科学基金面上项目,7212022,SAHA对前庭感觉上皮扁平化的阻逆作用及机制研究,2021.01-2023.12,20万元,负责人,已结题
5. 国家自然科学基金面上项目,81570912,Notch信号抑制剂与Atoh1可控性过表达共同诱导前庭毛细胞再生及机制研究,2016.01-2019.12,57万元,负责人,已结题
6. 国家自然科学基金青年基金,81100717,病毒载体介导BDNF过表达对前庭毛细胞和神经支配的保护作用,2012.01-2014.12,22万元,负责人,已结题
7. 北京市医院管理中心“青苗”人才培养计划,QML20180101,2019.01-2020.12,12万元,负责人,已结题
1. Hao MY#, Su W, Xu JY, Chen ZR,He L, Guo JY, Liu K, Gong SS*, Wang GP*. Co-overexpression of Atoh1, Pou4f3, and Gfi1 enhances thetransdifferentiation of supporting cells into hair cells in the neonatal mouseutricle. Neuroscience Letters. 2025 Feb 16;849:138136.
2. Guo JY#, Xu JY#, Gong SS*, Wang GP*. Roles of supporting cells in the maintenance andregeneration of the damaged inner ear: A literature review. Journal of Otology,2024. 19: 234-240.
3. Dai C#, Zhao P*., Wang G*, Ding H, Lv H, Qiu X, Tang R, Xu Ning, Huang Y,He K, Yang Z, Gong S, Wang Z*. Hemodynamic assessments of unilateral pulsatiletinnitus with jugular bulb wall dehiscence using 4D flow magnetic resonanceimaging. Quantitative Imaging in Medicine and Surgery 2024; 14(1): 684-697.
4. Chen ZR#, Guo JY#, He L, Liu S, Xu JY, Yang ZJ, Su W, Liu K, Gong SS*, WangGP*. Co-transduction ofdual-adeno-associated virus vectors in the neonatal and adult mouse utricles.Frontiers in Molecular Neuroscience 2022;15:1020803.
5. Li D#, Wang G#, Zeng R, Li W, Chen N, Zhao P, Wang Z*, Gong S*. Analysis of RevisionSurgery Following Surgical Reconstruction of the Sigmoid Sinus Wall in Patientswith Pulsatile Tinnitus. The Journal of International Advanced Otology 2022;18(4): 358-364.
6. He L#, Wang GP#, Guo JY, Chen ZR, Liu K, Gong SS*. Epithelial-MesenchymalTransition Participates in the Formation of Vestibular Flat Epithelium.Frontiers in Molecular Neuroscience 2021; 14:809878.
7. Guo JY#, He L, Chen ZR, Liu K,Gong SS, Wang GP*. AAV8-mediatedAtoh1 overexpression induces dose-dependent regeneration of vestibular haircells in adult mice. Neuroscience Letters 2021; 747:135679.
8. He L#, Guo JY, Qu TF, Wei W, Liu K, Peng Z, Wang GP*,Gong SS*. Cellular origin and response of flat epithelium in thevestibular end organs of mice to Atoh1 overexpression. Hearing Research 2020; 391:107953. (被选为杂志封面)
9. He L#, Guo JY, Liu K, Wang GP*, Gong SS*. Research progress on flat epithelium of the inner ear. Physiological Research 2020; 69:775-785.
10. Guo JY#, He L, QuTF, Liu YY, Liu K, Wang GP*, GongSS*. Canalostomy As a Surgical Approach to Local Drug Delivery intothe Inner Ears of Adult and Neonatal Mice. Jove-Journal of Visualized Experiments. 2018 May 25;(135): 57351.
11. Yang DH#, Xie J#,Liu K, Peng Z, Guo JY, Yu SK, Wang GP*,Gong SS*. The histone deacetylase inhibitor sodium butyrate protects against noise-inducedhearing loss in Guinea pigs. Neuroscience Letters 2017;660:140-146.
12. Guo JY#, Liu YY,Qu TF, Peng Z, Xie J, Wang GP*, GongSS*. Cochleovestibular gene transfer inneonatal mice by canalostomy. Neuroreport 2017; 28:682-688.(被选为杂志封面)
13. Wang GP#, Basu I, Beyer LA, Wong HT, Swiderski DL, GongSS, Raphael Y*. Severe streptomycin ototoxicity in the mouse utricle leadsto a flat epithelium but the peripheral neural degeneration is delayed. Hearing Research 2017; 355:33-41.

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