1、北京市自然科学基金-海淀原始创新联合基金，Cir_AFF4通过靶向miR-935/STAT1通路对骨质疏松影响的研究，2023/01-2026/12，主持

2、国家自然科学基金委员会，面上项目，81472139、骨性关节炎中C/EBPB调控机理的研究，2015/01-2018/12，已结题，主持。

3、国家自然科学基金委员会，重点项目，81330043、HIF-2A在骨关节退行性病变中的调控作用机制及其应用基础研究，2014/01-2018/12，已结题，参加。

4、国家科技部，十二五科技支撑计划课题, 2012BAI10B02，骨科退行性疾病防控研究，2012.01-2015.12，已结题，参加。

5、北京市科学技术委员会，科技计划课题，D131100005313013，北京骨科疾病临床数据与样本资源库发展与应用研究，2014.01-2015.12，已结题，参加。

6、国家自然科学基金委员会，面上项目，81071499，骨性关节炎中WISP-1调控机理的研究，2011/01-2013/12，已结题，主持。

7、北京自然基金委员会，面上项目，7102081，骨性关节炎中asporin调控机理及临床应用的研究，2011/01-2013/12，已结题，主持。

1: LiB, Shen E, Wu Z, Qi H, Wu C, Liu D, Jiang X. BMSC-Derived Exosomes AttenuateRat Osteoarthritis by Regulating Macrophage Polarization through PINK1/ParkinSignaling Pathway. Cartilage. 2024 Apr 20:19476035241245805. doi: 10.1177/19476035241245805.

 2:Jiang X, Wang Q, Wang C, Zhang Y, Wei Z, Wu Z, Yu S, Wu C. The association betweengenetic polymorphisms of matrix metalloproteinases and knee osteoarthritis:A systematic review and meta-analysis. Int J Rheum Dis. 2024 Mar;27(3):e15123.doi: 10.1111/1756-185X.15123. PMID: 38514927.

3: LiS, Sheng Y, Wang X, Wang Q, Wang Y, Zhang Y, Wu C, Jiang X. Biallelic variantsin SLC26A2 cause multiple epiphyseal dysplasia-4 by disturbing chondrocytehomeostasis. Orphanet J Rare Dis. 2024 Jul 2;19(1):245. doi: 10.1186/s13023-024-03228-4.PMID: 38956600; PMCID: PMC11220988.

 4: YuS, Shu X, Wang X, Sheng Y, Li S, Wang Y, Zhang Y, Tao J, Jiang X, Wu C. Thenovel HSP90 monoclonal antibody 9B8 ameliorates articular cartilage degenerationby inhibiting glycolysis via the HIF-1 signaling pathway. Heliyon. 2024Aug 8;10(16):e35603. doi: 10.1016/j.heliyon.2024.e35603. PMID: 39229534; PMCID:PMC11369415.

 5: WuC, Wang C, Xiao B, Li S, Sheng Y, Wang Q, Tao J, Zhang Y, Jiang X. Integrationanalysis of lncRNA and mRNA expression data identifies DOCK4 as a potentialbiomarker for elderly osteoporosis. BMC Med Genomics. 2024 Mar 5;17(1):70.doi: 10.1186/s12920-024-01837-3. PMID: 38443923; PMCID: PMC10916189.

 6: LiS, Sheng Y, Wang X, Wang Y, Zhang Y, Wu C, Jiang X. Analysis of genetic variantsand molecular pathogenesis in a Chinese pedigree affected with Multiple epiphysealdysplasia. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2024 Jul 10;41(7):807-811.Chinese. doi: 10.3760/cma.j.cn511374-20230515-00286. PMID: 38946362.

7:WangC, Yang X, Zhang H, Zhang Y, Tao J, Jiang X, Wu C. Temporal trends in mortalityof tuberculosis attributable to high fasting plasma glucose in China from1990 to 2019: a joinpoint regression and age-period-cohort analysis. Front PublicHealth. 2023 Jul 27;11:1225931. doi: 10.3389/fpubh.2023.1225931. PMID: 37575123;PMCID: PMC10413982.

 8:Zhang YZ, Wei ZJ, Yu SN, Wang XY, Wang Y, Wu CA, Jiang X. Dihydrotanshinone I protectshuman chondrocytes and alleviates damage from spontaneous osteoarthritisin a guinea pig model. Sci Rep. 2023 Dec 4;13(1):21355. doi: 10.1038/s41598-023-48902-y.PMID: 38049518; PMCID: PMC10696037.

9: LiS, Yu S, Zhang Y, Wang Y, Jiang X, Wu C. Compound heterozygous loss-of-functionvariants in BRAT1 cause lethal neonatal rigidity and multifocal seizure syndrome.Mol Genet Genomic Med. 2023 Jan;11(1):e2092. doi: 10.1002/mgg3.2092. Epub2022 Nov 11. PMID: 36367347; PMCID: PMC9834191.