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专注于儿童脑功能及相关疾病的临床及基础研究。2019年加入重症医学科团队,从事儿童危重症临床科研工作,研究领域涉及严重脓毒症/脓毒性休克、脓毒性相关脏器损伤、儿童危重症营养支持等。以课题负责人身份先后承担着国家自然科学基金、北京市自然基金、荷兰NutriciaResearch Foundation“国际青年学者交流项目”等项目,同时参与国家自然科学基金、北京市自然科学基金等10余项课题研究,并于2012年入选北京市科技新星。共发表论文40余篇,其中16篇被SCI收录。
1.2024-2026:补体抑制剂在脓毒症相关性脑病中的潜在治疗价值探索 -- 50万元,北京市科技新星交叉项目(负责人:樊超男)
2.2022-2024:氨基酸型肠内营养制剂在中国PICU喂养不耐受危重症婴儿中临床应用的真实世界研究--40万元,白求恩公益基金会项目(负责人:樊超男)
3.2018-2021:生命早期不同含量的n-3多不饱和脂肪酸对骨髓间充质干细胞向脑迁徙及分化的影响-- 20万元,北京市自然科学基金面上项目(7182052)(负责人:樊超男)
4.2013-2015:孕期及哺乳期n-6/n-3脂肪酸对小鼠脑源性神经营养因子基因甲基化影响的研究 – 北京市科委新星计划项目 (xx2012047)(负责人:樊超男)
5.2012-2014:孕期及哺乳期n-6/n-3脂肪酸变化对小鼠脑神经细胞发生及凋亡影响研究 -- 国家自然科学基金(青年)项目(81100630)(负责人 -- 樊超男)
6.International Training Fellewship -- Nutricia Research Foundation(2011-T2)(被培养人:樊超男)
1.Fan C, Hao C, Li K, Chen L, Wang Y, Gao H,Li W, Qian S. Clinical and genetic characteristics of RANBP2 mutations inchildren with acute necrotizing encephalopathy. Neurol Sci. 2024 Dec 23.
2. Li F, LiK, Wang Q, Qian S, Fan C (通讯作者). Predictive value of ANE-SS combined with ferritin andDIC scores for mortality Risk in children with acute necrotizingencephalopathy. Transl Pediatr. 2025 Jan 24;14(1):42-51.
3. Fan C,Li R, Wang L, Li K, Jia X, Gao H, Zhang B, Xu X, Qian S. Fecal MicrobiotaTransplantation for Severe Infant Botulism, China. Emerg Infect Dis. 2024Aug;30(8):1732-1734.
4.Li R, Liu G, Liu J, Qian S, Fan C(通讯作者). Three pediatric cases ofStaphylococcus aureus-associated hemophagocytic lymphohistiocytosis. PediatrNeonatol. 2024 Mar;65(2):207-208.
5. Fan C,Yang M, Mao Y, Fang B, He Y, Li R, Qian S. Effect of Antimicrobial Stewardship2018 on severe pneumonia with bacterial infection in paediatric intensive careunits. J Glob Antimicrob Resist. 2024 Mar;36:444-452.
6. Fan C,Mao Y, Liu J, Gao H, Fang B, Li R, Liu G, He Y, Qian S. Dynamics of plateletparameters in children with severe community-acquired pneumonia between viraland bacterial infections. Transl Pediatr. 2024 Jan 29;13(1):52-62.
7. Shi Y#, FanC#, Li K, Yuan M, Shi T, Qian S, Wu H. Fish oil fat emulsion alleviatestraumatic brain injury in mice by regulation of microglia polarization.Neurosci Lett. 2023; 804:137217.
8. FanCN, Fang BL, Gao HM, Li RB, Su GY, Mao YY, He YS, Wang Y, Zhou XH, Cai LM,Wang YQ, Blumenthal JA, Qian SY. Applications of mPCR testing reduced initialantibiotic use and duration of mechanical ventilation in virus-infectedchildren with severe community-acquired pneumonia admitted to the PICU. World JPediatr. 2022 Mar 29:1-4.
9. Lu Y#, FanC#, Liang A, et al. Effects of SCFA on the DNA methylation pattern ofadiponectin and resistin in high-fat-diet-induced obese male mice. Br J Nutr.2018; 120(4):385-392.
10. Fan C#, Fu H#, Dong H,Lu Y, Lu Y, Qi K*. Maternal n-3 polyunsaturated fatty aciddeprivation during pregnancy and lactation affects neurogenesis and apoptosisin adult offspring: associated with DNA methylation of brain-derivedneurotrophic factor transcripts. Nutr Res. 2016; 3 6: 1013-1021.
11. FanC, Sun W, Dong H, Fu H, Xia L, Lu Y, Deckelbaum RJ and Qi K*. Dietaryratios of n-6/n-3 polyunsaturated fatty acids during maternal pregnancy andlactation affect hippocampal neurogenesis and apoptosis in mouse offspring.Nutr. Hosp. 2015; 32(3): 1170-1179.
12. FanC#, Dong H#, Shen W, Xia L, Qi K*. Genome-widescreen of promoter methylation identifies novel markers in diet induced obesemice. Nutr. Hosp.2014; 30(1): 42-52.
13. FanC, Zirpoli H, Qi K. n-3 fatty acids modulate adipose tissue inflammationand oxidative stress. Curr. Opin. Clin. Nutr. Metab. Care. 2013;16(2):124-132.(
14. Fan C#, Liu X#, Shen W, Tian C, Deckelbaum RJ, Qi K*. The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortinExpression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to theMethylation of Their Promoters. Nutri Metab(Lond). 2011; 8:31.
15. Tian C#, Fan C#, Liu X, Xu F, Qi K*. Brain Histological Changes in Young Mice Submitted to Diets withDifferent Ratios of n-6/n-3 Polyunsaturated Fatty Acids during MaternalPregnancy and Lactation. Clin Nutr.2011;30(5): 659-667.
16. Zhu H#,Fan C#, Xu F, Jiang J, Tian C, Zhang F, Qi K*. Dietary fish oiln-3 PUFAs and alpha-linolenic acid differently affect brain accretion of DHAand expression of desaturases and SREBP-1 in mice. J Nutri Biochem. 2010;21(10):954-960.
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