主持：

国家自然基金青年项目1项《基于Sirt1/FoxO1通路促进血管新生探讨柴胡疏肝散“行气解郁”的神经再生机制》

北京市自然基金青年项目1项《基于SKA2调节内源性神经干细胞增殖的理论探讨柴胡疏肝散行气解郁的作用机制》

首都卫生发展基金自主创新项目1项《电针干预“代谢相关脂肪性肝病”的多中心随机对照临床研究》

参与：

“四大慢病”国家重大研发项目《基于代谢相关脂肪性肝病临床分型和结局的精准干预研究》

北京市中医药管理局《2023年北京市中西医协同重大疑难疾病攻关项目-脂肪肝》

以第一/通讯作者发表文章40篇，被引280次。

1.  Hu Y#, Zhao J#, Jin Y, Du Y, Zhao Q, Xu S, Li L*, Zhou Y*. The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus. Brain Imaging Behav. 2025,19(1): 23-31.

2. Shi W, Zhang S, Yao K, Meng Q, Lu Y, Ren Y, Li L*, Zhao J*. Breakdown of the blood-brain barrier in depressed mice induced by chronic unpredictable mild stress. J Psychiatr Res. 2024,180:138-146.

3. Zhao J, Zhao X,Wang Q, Ren H, Cao DI, Hu X, Yang L, Chen W, Yang JW, You H. Efficacy andsafety of electroacupuncture for metabolic dysfunction-associated fatty liverdisease: a study protocol for a multicentre, randomised, sham acupuncture-controlled,patient-blinded clinical trial. BMJ Open. 2024,14(11):e084768.

4. Ren Y, Xiao K, Lu Y, Chen W, Li L*, Zhao J*. Deciphering the mechanism of Chaihu Shugan San in the treatment of nonalcoholic steatohepatitis using network pharmacology and molecular docking. J Pharm Pharmacol. 2024,76(11):1521-1533.

5. Zhao J, Wang Q, Zhao X,Wu L, Li J, Zhang W, Xu S, Han C, Du Y, Tong X, Duan W, Cao D, Ren H, Zhao X,Ou X, Jia J, You H*. Electro-acupuncture reduced steatosis on MRI-PDFF inpatients with non-alcoholic steatohepatitis: a randomized controlled pilotclinical trial. Chin Med. 2023,18(1):19.

6. Zhang S, Lu Y, Shi W, Ren Y, Xiao K, Chen W, Li L, ZhaoJ*. SIRT1/FOXO1 Axis-Mediated Hippocampal Angiogenesis is Involved in theAntidepressant Effect of Chaihu Shugan San. Drug Des Devel Ther. 2022,16:2783-2801.

7. Zhao J#, Shi W#, Lu Y, Gao X, Wang A, Zhang S, DuY, Wang Y, Li L*. Alterations of monoamine neurotransmitters, HPA-axis hormones,and inflammation cytokines in reserpine-induced hyperalgesia and depressioncomorbidity rat model. BMC Psychiatry. 2022, 22(1):419.

8. Zhang S, Lu Y, Chen W, Shi W, Zhao Q, Zhao J*,Li L*. Network Pharmacology and Experimental Evidence: PI3K/AKT SignalingPathway is Involved in the Antidepressive Roles of Chaihu Shugan San. Drug DesDevel Ther. 2021,15:3425-3441.

9. Shi W, Zhang S, Lu Y, Wang Y, Zhao J*, Li L*. Tcell responses in depressed mice induced by chronic unpredictable mild stress.J Affect Disord. 2022, 296:150-156.

10. Zhao J, Gao X, Wang A, Wang Y, Du Y, Li L, LiM, Li C, Jin X, Zhao M*. Depression comorbid with hyperalgesia: Different rolesof neuroinflammation induced by chronic stress and hypercortisolism. J AffectDisord. 2019,256:117-124.