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1. 国家自然科学基金面上项目,急性闭角型青光眼晶状体悬韧带异常的机制研究,项目批准号:82371052,项目起止年月:2024年1月-2027年12月,46万,在研,主持。
2. 高层次公共卫生技术人才建设项目,原发性急性闭角型青光眼防盲新模式的评价研究,项目起止年月:2022年1月-2024年1月,90万元,结题,主持。
3. 国家自然科学基金面上项目,适合原发性急性闭角型青光眼中国患者特点的治疗模式筛选和临床评价,项目批准号:82171049,项目起止年月:2022年1月-2025年12月,75万,在研,主持。
4. 北京市卫生健康委员会首都卫生发展科研专项项目重点攻关,原发性可疑房角关闭患者队列房角关闭的危险因素及预测模型的临床研究,项目批准号:首发 2022-1-2052,项目起止年月:2022年1月-2024年12月,90万元,结题,主持。
5. 国家自然科学基金面上项目,原发性闭角型青光眼慢性房角关闭的粘连机制研究,项目批准号:81970797,项目起止年月:2020年1月-2023年12月,55万,完成,主持。
6. 首都卫生发展科研专项,急性闭角型青光眼单次发作后对视网膜和视神经影响的观察性研究,项目编号:首发2016-2-1081,项目起止年月:2016年1月-2018年12月,40万,完成,主持。
7. 北京市自然科学基金,病理状态下大鼠Muller 细胞表达肿瘤坏死因子α的机制研究,项目批准号:7152038,项目起止年月:2015年1月-2017年12月,15万,完成,主持。
8. 国家自然科学基金青年项目,Muller细胞在视网膜神经节细胞继发性损伤中作用的实验性研究,项目批准号:30700921,项目起止年月:2008年1月-2011年12月
SCI发表:(近5年,一作/通讯作者)
1.Feng H, Han D, Lu W, Tang G, Zhang H, Fan S, Lv A, Jiang J, Zhang Q, Zhang Y, Cao K, Li Z, Li S. Efficacy of Morning Versus Evening Latanoprost/Timolol Fixed Combination for Open-Angle Glaucoma and Ocular Hypertension: A Randomized Clinical Trial. Transl Vis Sci Technol. 2024 Jan 2;13(1):21. doi: 10.1167/tvst.13.1.21. PMID: 38285464; PMCID: PMC10829799.
2.Li C, Cheng Y, Zhang Y, Pan X, Feng H, Xiang F, Zhang M, Ji Q, Li Z, Jiang N, Zhang Q, Li S. Variation in Retinal Nerve Fiber Layer and Ganglion Cell Complex Associated With Optic Nerve Head Size in Healthy Eyes. Transl Vis Sci Technol. 2023 Mar 1;12(3):26. doi: 10.1167/tvst.12.3.26. PMID: 36971677; PMCID: PMC10064928.
3.Shan J, Li Z, Ma P, Tun TA, Yonamine S, Wu Y, Baskaran M, Nongpiur ME, Chen D, Aung T, Li S, He M, Yang Y, Han Y. Deep Learning Classification of Angle Closure based on Anterior Segment OCT. Ophthalmol Glaucoma. 2024 Jan-Feb;7(1):8-15. doi: 10.1016/j.ogla.2023.06.011. Epub 2023 Jul 16. PMID: 37437884.
4.Xiang F, Zhang Y, Zhang Q, Pan X, Feng H, Zhang M, Li C, Ji Q, Li Z, Li S. Characteristics of beta parapapillary atrophy in primary angle-closure suspect. BMJ Open Ophthalmol. 2024 Apr 15;9(1):e001529. doi: 10.1136/bmjophth-2023-001529. PMID: 38626931; PMCID: PMC11029359.
5.Li M, Li Z, Xiang F, Li C, Zhang Y, Li S. Correlation between choroidal parameters and primary angle-closure suspect in different age groups. BMJ Open Ophthalmol. 2024 Aug 22;9(1):e001772. doi: 10.1136/bmjophth-2024-001772. PMID: 39179254; PMCID: PMC11344506.
6.Zhang Y, Zhang X, Zhang Q, Lv B, Hu M, Lv C, Ni Y, Xie G, Li S, Zebardast N, Shweikh Y, Wang N. Automated classification of angle-closure mechanisms based on anterior segment optical coherence tomography images via deep learning. Heliyon. 2024 Jul 26;10(15):e35236. doi: 10.1016/j.heliyon.2024.e35236. PMID: 39166052; PMCID: PMC11334645.
7.Zhang Q, Feng H, Zhang Y, Han D, Tang G, Fan SJ, Zhang H, Jiang J, Lv A, Li S. Comparing 24-hour IOP fluctuation slope curve between newly diagnosed ocular hypertension and primary open-angle glaucoma. BMJ Open Ophthalmol. 2024 Sep 23;9(1):e001821. doi: 10.1136/bmjophth-2024-001821. PMID: 39313295; PMCID: PMC11418482.
8.Li M, Zhang Q, Zhang Y, Cao K, Pan X, Feng H, Xiang F, Li Z, Li S. Retinal ganglion cell complex thickness in subjects with diabetes mellitus and uncontrolled hypertension in China. BMC Ophthalmol. 2024 Aug 27;24(1):379. doi: 10.1186/s12886-024-03644-x. PMID: 39192272; PMCID: PMC11351316.
9.Li Z, Fan N, Cheng Y, Xiang F, Pan X, Cao K, Zhang Y, Zhang Q, Li S. Factors associated with severe corneal endothelial damage following acute primary angle closure in Chinese subjects. Graefes Arch Clin Exp Ophthalmol. 2023 May 25. doi: 10.1007/s00417-023-06109-x. Epub ahead of print. PMID: 37231278.
10.Zhang Y, Zhang Q, Li SZ, He MG, Li SN, Wang NL. Anterior Segment Characteristics and Risk Factors for Primary Angle Closure Disease With Long Axial Lengths: The Handan Eye Study. Invest Ophthalmol Vis Sci. 2023 Jan 3;64(1):8. doi: 10.1167/iovs.64.1.8. PMID: 36633876; PMCID: PMC9840442.
11.Yan F, Wang X, Jiang X, Chai Y, Zhang J, Liu Q, Wu S, Wang Y, Wang N, Li S. Proteomic profiles of the retina in an experimental unilateral optic nerve transection: Roles of Müller cell activation. Clin Transl Med. 2022 Apr;12(4):e631. doi: 10.1002/ctm2.631. PMID: 35474440; PMCID: PMC9043120.
12.Xie Q, Ma P, Patlidanon J, Saifee M, Yonamine S, Yu Y, Ying GS, Yang Y, Li S, Han Y. Anterior Segment OCT in Primary Angle Closure Disease Compared With Normal Subjects With Similar Shallow Anterior Chamber. J Glaucoma. 2022 Feb 1;31(2):84-90. doi: 10.1097/IJG.0000000000001915. PMID: 34366393; PMCID: PMC8795465.
13.Pan X, Ruan MZC, Fan W, Cao K, Feng H, Hu Z, Yang Y, Yan F, Zhao M, Liu Q, Fu M, Xiang F, Lee R, Li S, Han Y. Retina Vascular Structures near the Optic Disc and in the Macula in Primary Angle-Closure Suspects. Ophthalmic Res. 2022;65(5):575-583. doi: 10.1159/000520030. Epub 2021 Oct 14. PMID: 34649251.
14.Tang Y, Pan X, Cao K, Feng H, Yang Y, Hu Z, Yan F, Han Y, Li S. Ganglion Cell Complex Parameters in Primary Angle Closure Suspects. Ophthalmic Res. 2021;64(5):844-850. doi: 10.1159/000516538. Epub 2021 Jun 17. PMID: 34139705.
15.Li S, Tang G, Fan SJ, Zhai G, Lv J, Zhang H, Lu W, Jiang J, Lv A, Wang N, Cao K, Zhao J, Vu V, Mu D, Pan X, Feng H, Hsia YC, Han Y. Factors associated with blindness three months following treatment for acute primary angle glaucoma. Br J Ophthalmol. 2021 Apr;105(4):502-506. doi: 10.1136/bjophthalmol-2020-316259. Epub 2020 Aug 7. PMID: 32769077.
专利:
1.一种便携式可视化前房角分离器,实用新型专利,专利号ZL2021 2 1444955.8
2.一种原发性闭角型青光眼的房角关闭机制分型方法,发明专利,专利号ZL2021 1 1364339.6
3.Tenon囊下注药装置,发明专利,专利号ZL2016 1 0519622.4

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