围绕“神经介入器械及医学仪器”，累计授权专利16项，其中发明专利5项 。主持国家自然科学基金、北京自然科学基金、首都医学创新中心协调创新项目等省部级项目8项，累计科研经费近800万。

1 神经科学医工交叉平台建设项目 首都医学科学创新中心重点培育项目 2025-2027 600万 主持

2 基于靶向低温的缺血性脑卒中神经保护医学仪器研制 首都卫生发展脑重大疾病科研专项  2025-2027 40万 主持     

3 基于光学高分辨显微技术的神经介入内窥成像导管系统研制与应用研究 中国医学科学院 2025-2027 40万 主持      

4 生物传热数值仿真与多模态影像协同优化的脑温预测模型构建及其温度成像研究 国家自然科学基金（青年基金）2025-2027 30万 主持 

5 基于多物理场耦合的神经介入导管隔热设计及在血管内低温神经保护中的安全有效性研究 北京自然科学基金（青年基金）2024-2025 20万 主持      

6 基于智能传感与无创监测的新一代低温神经保护医学仪器的研制首都医科大学（重点项目）2025-2026 10万 主持      

7 基于多物理场耦合的神经介入导管隔热设计及在血管内低温神经保护中的安全有效性研究 首都医科大学（自然科学培育基金）2024 5万 主持     

8 基于IPv6云计算技术的超大型3D打印模型切片处理技术研究 教育部（下一代互联网技术创新项目）2017-2019 10万 主持       

9 多孔结构低温介入柔性导管研制及其应用研究 北京医管局扬帆（3.0医工结合培育项目） 2025-2027 25万 子课题负责人 

代表性论著与知识产权 (其中论著均为第一/通讯，含共同)

(1)  神经介入器械：仪器科学（低温神经保护医学仪器）

1.       Zhang Y#, Jiang M#,Wei M#, Wu C#, Huang Y, Song B, et al. MgSO4 as a novel hypothermia infusionsolution promotes ischemic stroke recovery through Ca2+ regulation ofneurovascular units. Theranostics. 25,15(5): 1896.

2.       Li M#, Gao Y#, Jiang M#, Zhang H, Zhang Y, Wu Y, et al.Dual-sized hollow particle incorporated fibroin thermal insulating coatings oncatheter for cerebral therapeutic hypothermia. Bioactive Materials. 2023, 26: 116-127.

3.       Jiang M#, Zhang Y#, Gao Y#, Xu S, Qi Z, Wu C,et al. A computationally guided study of a blood heat exchanger and theconstruction of an extracorporeal circulation system for selective braincooling. CellReports Physical Science. 2024. 5(6)

4.       Jiang M#, Cao F#, Zhang Q#, Qi Z, Gao Y, ZhangY, et al. Model-predicted brain temperature computational imaging by multimodalnoninvasive functional neuromonitoring of cerebral oxygen metabolism andhemodynamics: MRI-derived and clinical validation. Journal of Cerebral Blood Flow & Metabolism. 2025, 45(2): 275-291.

5.       Zhang Y#, Jiang M*,Baoying S, Gao Y, Xu Y, Qi Z, et al. Trends and hotspots of the neuroprotectionof hypothermia treatment: A bibliometric and visualized analysis of researchfrom 1992 to 2023. CNS Neuroscience & Therapeutics. 2024, 30(6): e14795.

6.       Fang J, Song B, Li L, Tong L, Jiang M*, Yan J*. RGX Ensemble Model forAdvanced Prediction of Mortality Outcomes in Stroke Patients. BME frontiers. 2024, 5: 0077.

7.       Jiang M, Li M, Gao Y, Yin Z, Ding Y, Zheng Y,et al. Design and evaluation of an air-insulated catheter for intra-arterialselective cooling infusion from numerical simulation and in vitro experiment. Medical Engineering &Physics. 2022, 99: 103736.

8.       Jiang M#, Li M#, Gao Y, Wu L, Zhao W, Li C, etal. The intra‐arterial selective cooling infusion system: A mathematicaltemperature analysis and in vitro experiments for acute ischemic stroketherapy. CNSNeuroscience & Therapeutics.2022, 28(9): 1303-1314.

9.       Jiang M, Gao Y, Wu C, Wu L, Tang S, Yin Z, etal. The blood heat exchanger in intra-arterial selective cooling infusion foracute ischemic stroke: A computational fluid-thermodynamics performance,experimental assessment and evaluation on the brain temperature. Computers in Biology andMedicine. 2022,145: 105497.

10.   吉训明; 姜缪文; 李明; 郑玉峰; 陈冬冬; 尹志臣. 成像导管及血管内成像系统. 2023-09-12，中国发明，CN116138716B

11.   吉训明; 李明; 尹志臣; 高原; 姜缪文; 鲍路姿; 丁玉川; 吴川杰; 吴隆飞. 低温治疗导管和低温治疗系统. 2024-08-16, 中国发明，CN111419528B

(2)  神经介入器械：生物材料（可降解颅内动脉脑血管支架）

1.       Zhang Y#, Zhang H#, Jiang M#, Cao X, Ge X, Song B, et al.Neuroprotection on ischemic brain injury by Mg2+/H2released from endovascular Mg implant. Bioactive Materials. 2024, 42: 124-139.

2.       Wang L#, Hu Y#, Zhang H#, Jiang M#, Zhang Y, Luo Y, et al.Neuroprotective effects of intraperitoneally injected Mg alloy extracts onmiddle cerebral artery occluded mouse with reperfusion injury. Journal of Magnesium andAlloys. 2024. Online

3.       Song B#, Jiang M#,Zhang Y#, Xu Y, Wu C, Wu D, et al. Research hotpots and frontier trends ofneuroprotective effects of magnesium from 1999 to 2023: A bibliometricanalysis. CNSNeuroscience & Therapeutics.2024, 30(2): e14597.

4.       Zhang Y#, Shen Y#, Jiang M#, Liu G, Zhang H, Song B, et al.Gene-based safety evaluation of molybdenum-containing biomaterials forcardiovascular and cerebrovascular diseases. Genes & Diseases. 2025: 101516. (Accept)

5.       吉训明; 李明; 高原; 尹志臣; 丁玉川; 鲍路姿; 姜缪文; 李思颉; 吴隆飞; 吴川杰. 一种丝素蛋白涂层的制备方法. 2021-09-03, 中国发明，CN110982429B

6.       吉训明; 高原; 李明; 尹志臣; 丁玉川; 鲍路姿; 姜缪文; 李思颉; 吴隆飞; 吴川杰. 蛋白质类水溶液喷涂设备. 2021-07-20, 中国发明，CN111054567B

(3)  神经介入器械：生物力学（新型脑静脉取栓系统）

1.       Li M, Song B, Wu Y, Zhang Y, Cao X,Zhang H, et al, JiangM*, Ji X*. Dumbbell-shaped thrombectomydevice for cerebral venous sinus thrombus removal with controllable axial andlongitudinal maneuverability. National Science Review. 2025, 12(3): nwaf015.

2.       Li M#, Jiang M#,Gao Y, Zheng Y, Liu Z, Zhou C, et al. Current status and outlook ofbiodegradable metals in neuroscience and their potential applications ascerebral vascular stent materials. Bioactive Materials. 2022,11: 140-153.

3.       Xu Y#, Wu Y#, Jiang M#, Song B, Li C, Wu C, et al. Efficacyand Safety of a Dedicated Device for Cerebral Venous Thrombectomy: A PilotRandomized Clinical Trial. Stroke. 2025,56(1): 5-13.

4.       Kan Y, Song B, Jiang M#, Zhang Y, Li C, Wu C, et al. Evolutionand advances in endovascular mechanical thrombectomy of cerebral venous sinusthrombosis. InternationalJournal of Medical Sciences. 2024,21(13): 2450.

5.       He J, Zhang Y, Guo Y, Guo J, Chen X, XuS, et al, JiangM*, Ji X*. Blood-derived factors tobrain communication in brain diseases. Science Bulletin. 2024,69 (22): 3618-3632.

6.       吉训明; 姜缪文; 李明; 尹志臣; 鲍路姿; 高原; 吴隆飞; 李旻. 取栓支架及其制备方法、取栓装置. 2022-04-19, 中国发明，CN111437006B