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兰晶，首都医科大学脑重大疾病研究中心（北京脑重大疾病研究院），临床医学研究中心，临床科研复合岗，副研究员/主治医师。首都医科大学宣武医院神经病学博士，美国哈佛大学麻省总医院访问学者，北京市科技新星。主要从事脑卒中神经保护的基础临床转化研究，主持国家自然基金委和省部级课题共2项，作为课题骨干参与国家重点研发计划1项，以第一或通讯作者（含共同）在Lancet、The Lancet Neurology、Stroke等杂志发表高水平SCI论文多篇，获得北京医学科技奖二等奖1项。
1. 远隔缺血适应对脑卒中缺血半暗带的作用和机制，北京市科技新星计划，20230484286，主持，2023-11至2026-10，40万，在研
2. 侧枝循环内皮细胞RABEP2对缺血性卒中缺血半暗带的作用及机制研究，国自然青年项目，主持，82101389，2022-01至2024-12，30万，资助期满
3. 脑血管病及危险因素监测技术应用模式探索，国家重点研发计划，2023YFC2506602，课题骨干，2023-11至2026-10，在研
1. Li W#, Lan J#, Wei M#, Liu L, Hou C, Qi Z, Li C, Jiao L, Yang Q, Chen W, Liu S, Yue X, Dong Q, Yuan H, Gao Z, Wu X, Wen C, Li T, Jiang C, Li D, Chen Z, Shi J, Shi W, Yuan J, Qin Y, Li B, Fisher M, Feng W, Liu KJ, Ji X; OPENS-2 Investigators. Normobaric hyperoxia combined with endovascular treatment for acute ischaemic stroke in China (OPENS-2 trial): a multicentre, randomised, single-blind, sham-controlled trial. Lancet. 2025;405(10477):486-497.
2. Hou C#, Lan J#, Lin Y, Song H, Wang Y, Zhao W, Li S, Meng R, Hao J, Ding Y, Chimowitz MI, Fisher M, Hess DC, Liebeskind DS, Hausenloy DJ, Huang J, Li Z, Han X, Yang J, Zhou J, Chen P, Zhu X, Hu P, Pang H, Chen W, Chen H, Li G, Tao D, Yue W, Gao Z, Ji X; RICA investigators. Chronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham-controlled trial in China. Lancet Neurol. 2022;21(12):1089-1098.
3. Lan J, Esposito E, Ayata C, Singhal AB, Lo EH, Ji X. Different Effects of Normobaric Oxygen in Normotensive Versus Hypertensive Rats After Focal Cerebral Ischemia. Stroke. 2018;49(6):1534-1537.
4. Jia M, Yu W, Jin F, Xu J, Guo W, Zhang M, Li S, Ren C, Ding Y, Zhao W, Lan J*, Ji X*. Association of Alkaline Phosphatase Level with Futile Recanalization in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy. Curr Neurovasc Res. 2025;21(4):418-426.
5. Jia M, Xu S, Li D, Li S, Ren C, Zhao W, Lan J*,Ji X*. A prediction modelfor large vessel occlusion in suspected stroke patients based on availableprehospital information. Journal ofTranslational Neuroscience. Journal of Translational Neuroscience, 2024, 9(3): 26-35.
6. Esposito E, Li W, T Mandeville E, Park JH, Şencan I, Guo S, Shi J, Lan J, Lee J, Hayakawa K, Sakadžić S, Ji X, Lo EH. Potential circadian effects on translational failure for neuroprotection. Nature. 2020;582(7812):395-398.
7. Zhang Y, Zhang H, Jiang M, Cao X, Ge X, Song B, Lan J, Zhou W, Qi Z, Gu X, Liu J, Zheng Y, Li M, Ji X. Neuroprotection on ischemic brain injury by Mg2+/H2 released from endovascular Mg implant. Bioact Mater. 2024;42:124-139.
8. Li W, Wang S, Liu L, Chen J, Lan J, Ding J, Chen Z, Yuan S, Qi Z, Wei M, Ji X. Normobaric Hyperoxia Combined With Endovascular Treatment Based on Temporal Gradient: A Dose-Escalation Study. Stroke. 2024;55(6):1468-1476.
9. Wang X, Sun H, Wang X, Lan J, Guo Y, Liu W, Cui L, Ji X. More severe initial manifestations and worse short-term functional outcome of intracerebral hemorrhage in the plateau than in the plain. J Cereb Blood Flow Metab. 2024;44(1):94-104.
10. Yu Z, Li W, Lan J, Hayakawa K, Ji X, Lo EH, Wang X. EphrinB2-EphB2 signaling for dendrite protection after neuronal ischemia in vivo and oxygen-glucose deprivation in vitro. J Cereb Blood Flow Metab. 2021;41(7):1744-1755.
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