1. 血小板来源的LOXL1通过介导血小板-LSEC粘附促进NASH纤维化及机制研究，北京市自然科学基金面上项目。

2. ECM1高表达的肝星状细胞亚群对NASH纤维化逆转的作用及机制研究，国家自然科学基金面上项目。

1.Yang AT, Kim YO, Yan XZ, Abe H, Aslam M, Park KS, Zhao XY, Jia JD, Klein T, You H, Schuppan D. Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis. Cell Mol Gastroenterol Hepatol. 2023;15(4):841-867. doi: 10.1016/j.jcmgh.2022.12.005.

2. Zhang N, Yang A, Zhang W, Li H, Xu A, Yan X, Han Q, Wang B, You H, Chen W. Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal. Hepatol Commun. 2024 Mar 11;8(4):e0391. doi: 10.1097/HC9.0000000000000391. 

3. Han Q, Yan X, Wang L, Zhang N, Zhang W, Li H, Chen W, You H, Yang A. Aryl hydrocarbon receptor attenuates cholestatic liver injury by regulating bile acid metabolism. Biochem Biophys Res Commun. 2023 Nov 19;682:259-265. doi: 10.1016/j.bbrc.2023.10.030.

4. Yan X, Zhang N, Wei L, Zhang W, Huang T, Li W, Chen W, Yang A, You H. Selective inhibition of hepatic stellate cell and fibroblast-derived LOXL1 attenuates BDL- and Mdr2-/--induced cholestatic liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 2023 Dec 1;325(6):G608-G621. doi: 10.1152/ajpgi.00004.2023.

5. Chen H, Zhao W, Yan X, Huang T, Yang A. Overexpression of Hepcidin Alleviates Steatohepatitis and Fibrosis in a Diet-induced Nonalcoholic Steatohepatitis. J Clin Transl Hepatol. 2022 Aug 28;10(4):577-588. doi: 10.14218/JCTH.2021.00289.

6. Yang A, Yan X, Xu H, Fan X, Zhang M, Huang T, Li W, Chen W, Jia J, You H. Selective depletion of hepatic stellate cells-specific LOXL1 alleviates liver fibrosis. FASEB J. 2021 Oct;35(10):e21918. doi: 10.1096/fj.202100374R.

7. Yang A, Yan X, Fan X, Shi Y, Huang T, Li W, Chen W, Jia J, You H. Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice. Hepatol Int. 2021 Oct;15(5):1122-1135. doi: 10.1007/s12072-021-10210-w.