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研究员，副教授，硕士生导师，入选北京市优秀人才（骨干）计划。
常年从事铁代谢相关疾病的机制研究，在国内外发表论文50余篇，作为第一作者或通讯作者被SCI收录论文17篇。
先后主持国家自然科学基金面上项目，北京市自然科学基金面上项目，中国肝炎防治基金会科研基金，首都医学发展科研基金等基金项目。
国家自然科学基金面上项目，项目批准号： 82370898，项目名称： TNFR2/Hippo/YAP轴介导TNFα上调肝窦内皮细胞BMP6表达在铁过载相关疾病中的作用及机制研究。
1. LiY, Xu A, Liu S, Zhang W, ZhouD, OuYang Q, Zi H, Zhang B, Zhang N, Geng W, Zhou Y, Duan W, Wang X, Zhao X, OuX, Fan C, Jia J, Huang J. SUGP2 p.(Arg639Gln) variant is involved in thepathogenesis of hemochromatosis via the CIRBP/BMPER signaling pathway. Am JHematol. 2024 Sep;99(9):1691-1703.
2. ZhangN, Yang P, Li Y, Ouyang Q, Hou F, Zhu G, Zhang B, Huang J, Jia J*, Xu A*. Serum Iron Overload Activates the SMAD Pathway and HepcidinExpression of Hepatocytes via SMURF1. J Clin Transl Hepatol. 2024 Mar28;12(3):227-235.
3. LiuK, Liu J, Xu A*, Ding J*. The role of polydatin in inhibitingoxidative stress through SIRT1 activation: A comprehensive review of moleculartargets. J Ethnopharmacol. 2024 Sep 15;331:118322.
4. YanmengLi, Anjian Xu, Qin Ouyang, Wei Zhang, Chunpan Zhang, Zhibin Chen, DonghuZhou, Bei Zhang, Weijia Duan, Xinyan Zhao, Xiaoming Wang, Hong You, Xiaojuan Ou*, Jidong Jia*, Jian Huang*. DENND3p.L708V activating variant is involved in the pathogenesis of hereditaryhemochromatosis via the RAB12/TFR2 signaling pathway. HepatologyInternational. 2023 Jun;17(3):648-661.
5. Yanmeng Li, QinOuyang, Wei Chen, Ke Liu, Bei Zhang, Jingyi Yao, Song Zhang, Junying Ding*, MinCong*, AnjianXu*. An iron-dependent form ofnon-canonical ferroptosis induced by labile iron. SCIENCE CHINA Life Sciences, 2023Mar;66(3):516-527.
6. Yanmeng Li, Qin Ouyang, Caicai Jin,Zhibin Chen, Wei Chen, Bei Zhang, Song Zhang, Min Cong* and Anjian Xu*. Intracellular Labile Iron is a Key Regulator of HepcidinExpression and Iron Metabolism. Hepatology International. 2023Jun;17(3):636-647.
7. AnjianXu*,Jichao Zhou, Yanmeng Li, Luyao Qiao, Caicai Jin, Wei Chen, Lan. Sun, Shanna Wu,Xiaojin Li, Donghu Zhou, Siyu Jia, Bei Zhang, Jingyi Yao, Xiaowei Zhang*, Hong You*, Jian Huang*.14-kDa phosphohistidine phosphatase is apotential therapeutic target for liver fibrosis. Am J Physiol GastrointestLiver Physiol. 2021 Mar 1;320(3):G351-G365.
8. Yanmeng Li, Teng Li, Donghu Zhou, Jia Wei, ZhenkunLi, Xiaojin Li, Siyu Jia, Qin Ouyang, Saiping Qi, Zhibin Chen, Bei Zhang, JingYu, Jidong Jia*, Anjian Xu*, Jian Huang*. CellAdhesion & Migration. 2021Dec;15(1):249-260.
9. Lan Sun, Xiaona Zhou,Yanmeng Li, Wei Chen, Shanna Wu, Bei Zhang, Jingyi Yao, Anjian Xu*.KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in thecontext of p53 loss through miR-192 targeting of ZEB2. Cell Adhesion & Migration. 2020Dec;14(1):182-194.
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