1: 国家自然科学基金, 重大研究计划培育项目, MLK3在维持血管平滑肌细胞稳态及主动脉瘤/夹层发生发展中的保护作用, 2020-01-01 至 2021-12-31, 结题, 主持

2: 国家自然科学基金, 面上项目, 转录因子KLF15调节经典与非经典TGF-β通路抑制主动脉瘤发生, 2018-01-01 至 2021-12-31, 结题, 主持

3: 北京市自然科学基金,面上项目, 新易感基因DUSP22在高血压诱导胸主动脉夹层发病中的作用及机制, 2024-01 至 2026-12, 在研, 主持

4：北京市自然基金，面上项目, KLF15 在调控血管平滑肌细胞分化及腹主动脉瘤发生中的作用, 2019-01 至 2021-12, 结题, 主持

1: Li Y#, Gao S#, HanY#, Song L, Kong Y, Jiao Y, Huang S, Du J*, Li Y*. Variants of FocalAdhesion Scaffold Genes Cause Thoracic Aortic Aneurysm. Circulation Research.2021 Jan 8;128(1):8-23.

2: Fang G, Tian Y, Huang S, Zhang X, Liu Y, Li Y, Du J*,Gao S*. KLF15 maintains contractile phenotype of vascular smooth musclecells and prevents thoracic aortic dissection by interacting with MRTFB. J BiolChem. 2024 May;300(5):107260.

3: Gao S, Huang S, Zhang Y, Fang G, Liu Y,Zhang C*, Li Y*, Du J*. The transcriptional regulator KLF15 is necessary formyoblast differentiation and muscle regeneration by activating FKBP5. J BiolChem. 2023;299(10):105226.

4: Zhou Z#, Liu Y#, Gao S#,Zhou M, Qi F, Ding N, Zhang J, Li R, Wang J, Shi J, Yu R, Wang Y, Li Y, Pan J*,Du J*, Wang D*. Excessive DNA damage mediates ECM degradation via theRBBP8/NOTCH1 pathway in sporadic aortic dissection. Biochim Biophys Acta MolBasis Dis. 2022 Feb 1;1868(2):166303.

5: Huang S, Gao S, Shao Y, Li P, Lu J, Xu K, Zhou Z, Li Y*, Du J*.Gut microbial metabolite trimethylamine N-oxide induces aortic dissection. JMol Cell Cardiol. 2024 Apr;189:25-37.

6: Li Y#,Ma K#, Dong Z, Gao S, Zhang J, Huang S, Yang J, Fang G, Li Y,Li X, Welch C, Griffin EL, Ramaswamy P, Valivullah Z, Liu X, Dong J, Wang DW,Du J, Chung WK, Li Y. Frameshift variants in C10orf71 cause dilatedcardiomyopathy in human, mouse, and organoid models. J Clin Invest. 2024 Jun17;134(12):e177172.

7. Liu Y#, Shao Y#, Zhang J, Wang Y, Zhou M, Li H,Zhang C, Yu P, Gao S, Wang X, Jia L, Piao C, Du J, Li Y*. MacrophageCARD9 mediates cardiac injury following myocardial infarction throughregulation of lipocalin 2 expression. Signal Transduct Target Ther.2023;8(1):394.