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世纪坛医院胃肠外科副主任、主任医师、教授、博导,国家市场监管总局肿瘤特医食品重点实验室副主任。曾先后于三军大、福州总医院、联合国利比里亚维和部队、中山大学和耶鲁大学学习和工作。擅长肿瘤营养代谢治疗和癌性肠梗阻综合治疗,任国家自然科学基金委评审专家、中国抗癌协会中西医整合控瘤新药专委会副主委、中国抗癌协会中西医整合治疗专委会常委、中国抗癌协会营养专委会委员兼微生态学组组长等学术职务。主持国家和省级课题16项,发表论文115篇,获国家专利7项、省部级科技奖10项、联合国勋章2枚、三等功1次,省级“百千万”人才和敬业奉献道德模范。
饶本强教授领军人才团队包括正高级职称2位、副高级职称2位、中级职称3位、初级职称3位。此外,饶教授有在读博士3位、在读硕士4位以及联合培养研究生2位。
(1) 国家自然科学基金委员会, 面上项目, 82474333, 基于肿瘤病机代谢重编程理论探究“大剂量维生素C-加味大黄厚朴甘草汤”中西结合代谢配伍治疗肠癌科学内涵, 202501 至 202812, 48万元, 在研, 主持
(2) 中华人民共和国科学技术部, 科技部重大专项研究, 2022YFC2009601, 临床实验室检验新技术与参考系统建立研究, 202207 至 202506, 1982.36万元, 在研,参与
(3) 首都医科大学附属北京世纪坛医院,院基金,2024LJRCRBQ,首都医科大学附属北京世纪坛医院“十四五”期间人才培养项目,202401至202612,240万元,在研,主持
重要学术论文:
[1] Lu S, Sun X, Zhou Z, Tang H, XiaoR, Lv Q, et al. Mechanism of Bazhen decoction in the treatment of colorectalcancer based on network pharmacology, molecular docking, and experimentalvalidation. Front Immunol. 2023; 14: 1235575. https://doi.org/10.3389/fimmu.2023.1235575
[2] Lu S, Sun X, Tang H, Yu J, Wang B,Xiao R, et al. Colorectal cancer with low SLC35A3 is associated with immuneinfiltrates and poor prognosis. Sci Rep. 2024; 14: 329.https://doi.org/10.1038/s41598-023-51028-w
[3] Wang X, Liu MA, He J, Zhao WZ, WangYX, Yang LQ, et al. Dietary therapy of the herbal porridge improves thesymptoms of functional dyspepsia: A randomized, double-blind,placebo-controlled, clinical trial. Food Sci Nutr. 2024; 12: 2104-2114.https://doi.org/10.1002/fsn3.3911
[4] Lu S, Sun X, Zhang W, Li X, Zhou Z,Xiao R, et al. Effects of the Mediterranean Diet on metabolic indices andquality of life in cancer patients: A systematic review and meta-analysis ofrandomized controlled trials. Journal of Functional Foods. 2024; 114: 106074.
[5] Wang X, He J, Sun M, Wang S, Qu J,Shi H, et al. High-dose vitamin C as a metabolic treatment of cancer: a newdimension in the era of adjuvant and intensive therapy. Clin Transl Oncol.2024. https://doi.org/10.1007/s12094-024-03553-x
[6] Qu J, Lu S, Wang B, Wang S, Yang Z,Tang H, et al. Network pharmacology and molecular docking technology forexploring the effect and mechanism of high-dose vitamin c on ferroptosis oftumor cells: A review. Medicine (Baltimore). 2024; 103: e38189. https://doi.org/10.1097/md.0000000000038189
[7] Wang B, Ma R, Shi G, Fan X, Rao B,Xu H. Hyperthermic intraperitoneal chemotherapy in patients with incompletecytoreduction for appendiceal pseudomyxoma peritonei: a 10-year treatmentexperience in China. Orphanet J Rare Dis. 2024; 19: 8. https://doi.org/10.1186/s13023-023-02995-w
[8] Sun XB, Su HP, Jiang H, Wang B, LuS, Qu JX, et al. A systematic review of qualitative research on theself-management experience of breast cancer patients. Int J Health PlannManage. 2024; 39: 1131-1145. https://doi.org/10.1002/hpm.3765
[9] Xiong Q, Wang W, Wang Y, Zhang M,Rao B, Ji X, et al. Long-term exposures to ambient particulate matter and ozonepollution with lower extremity deep vein thrombosis after surgical operations:a retrospective case-control study in Beijing, China. BMC Public Health. 2023;23: 1956. https://doi.org/10.1186/s12889-023-16882-3
[10] Wang Y, Wen L, Tang H, Qu J, RaoB. Probiotics and Prebiotics as Dietary Supplements for the AdjunctiveTreatment of Type 2 Diabetes. Pol J Microbiol. 2023; 72: 3-9.https://doi.org/10.33073/pjm-2023-013
[11] Wang Y, Wang X, Xiao X, Yu S,Huang W, Rao B, et al. A Single Strain of Lactobacillus (CGMCC 21661) ExhibitsStable Glucose- and Lipid-Lowering Effects by Regulating Gut Microbiota.Nutrients. 2023; 15. https://doi.org/10.3390/nu15030670
[12] Wang B, Ma R, Rao B, Xu H. Serumand ascites tumor markers in the diagnostic and prognostic prediction forappendiceal pseudomyxoma peritonei. BMC Cancer. 2023; 23: 90.https://doi.org/10.1186/s12885-023-10545-7
[13] Zhang Z, Zhang Y, Tao X, Wang Y,Rao B, Shi H. Effects of Glucomannan Supplementation on Type II DiabetesMellitus in Humans: A Meta-Analysis. Nutrients. 2023; 15.https://doi.org/10.3390/nu15030601
[14] Wang B, Sun X, Ma R, Yang Z, TangH, Lu S, et al. Prognostic value of the ascites characteristics in pseudomyxomaperitonei originating from the appendix. Front Surg. 2022; 9: 967296.https://doi.org/10.3389/fsurg.2022.967296
[15] Tang HZ, Yang ZP, Lu S, Wang B,Wang YY, Sun XB, et al. Network pharmacology-based analysis of heat clearingand detoxifying drug JC724 on the treatment of colorectal cancer. World JGastrointest Oncol. 2023; 15: 90-101. https://doi.org/10.4251/wjgo.v15.i1.90
[16] Zhu Q, Rao B, Chen Y, Jia P, WangX, Zhang B, et al. In silico development and in vitro validation of a novelfive-gene signature for prognostic prediction in colon cancer. Am J Cancer Res.2023; 13: 45-65.
[17] Sun XB, Liu WW, Wang B, Yang ZP,Tang HZ, Lu S, et al. Correlations between serum lipid and Ki-67 levels indifferent breast cancer molecular subcategories. Oncol Lett. 2023; 25: 53.https://doi.org/10.3892/ol.2022.13639
[18] Zhao W, Zhang Q, Yang Z, Rao B,Chen Y, Yu K, et al. Association of differential body water composition by sex,measured using BIA, with survival in a real‑world lung cancer cohort. Nutrition.2022; 103-104: 111804. https://doi.org/10.1016/j.nut.2022.111804
[19] Wang B, Ma R, Shi G, Yang Z, TangH, Lu S, et al. Prognostic prediction of preoperative nutritional status inlow-grade appendiceal mucinous neoplasms. Sci Rep. 2022; 12: 10678.https://doi.org/10.1038/s41598-022-14765-y
[20] Yang Z, Tang H, Lu S, Sun X, RaoB. Relationship between serum lipid level and colorectal cancer: a systemicreview and meta-analysis. BMJ Open. 2022; 12: e052373.https://doi.org/10.1136/bmjopen-2021-052373
[21] Wang Y, Yang Z, Tang H, Sun X, QuJ, Lu S, et al. Faecal microbiota transplantation is better than probiotics fortissue regeneration of type 2 diabetes mellitus injuries in mice. Arch PhysiolBiochem. 2024; 130: 333-341. https://doi.org/10.1080/13813455.2022.2080229
[22] Yang Z, Lu S, Tang H, Qu J, WangB, Wang Y, et al. Molecular Targets and Mechanisms of Hedyotisdiffusa-Scutellaria barbata Herb Pair for the Treatment of Colorectal CancerBased on Network Pharmacology and Molecular Docking. Evid Based Complement AlternatMed. 2022; 2022: 6186662. https://doi.org/10.1155/2022/6186662
[23] Jin S, Qin D, Liang BS, Zhang LC,Wei XX, Wang YJ, et al. Machine learning predicts cancer-associated deep veinthrombosis using clinically available variables. Int J Med Inform. 2022; 161:104733. https://doi.org/10.1016/j.ijmedinf.2022.104733
[24] Tao X, Zhang Z, Yang Z, Rao B. Theeffects of taurine supplementation on diabetes mellitus in humans: A systematicreview and meta-analysis. Food Chem (Oxf). 2022; 4: 100106.https://doi.org/10.1016/j.fochms.2022.100106
[25] Lu S, Yang Z, Tang H, Sun X, WangB, Qu J, et al. Associations between omega-3 polyunsaturated fatty acidssupplementation and surgical prognosis in patients with gastrointestinalcancer: A systematic review and meta-analysis. Food Chem (Oxf). 2022; 4:100099. https://doi.org/10.1016/j.fochms.2022.100099
[26] Yang Z, Lu S, Wang Y, Tang H, WangB, Sun X, et al. A Novel Defined Necroptosis-Related miRNAs Signature forPredicting the Prognosis of Colon Cancer. Int J Gen Med. 2022; 15: 555-565.https://doi.org/10.2147/ijgm.S349624
[27] Wang X, Yang M, Ge Y, Tang M, RaoB, Chen Y, et al. Association of Systemic Inflammation and Malnutrition WithSurvival in Nasopharyngeal Carcinoma Undergoing Chemoradiotherapy: Results Froma Multicenter Cohort Study. Front Oncol. 2021; 11: 766398.https://doi.org/10.3389/fonc.2021.766398
[28] 赵婉妮, 杨振鹏, 饶本强, 石汉平. 糖尿病足与糖尿病患者血浆中差异表达的环状RNA和信使RNA的筛选及其作用分析. 中国医学前沿杂志(电子版). 2021; 13: 67-73.
[29] 孙龙凤, 王志超, 戴猛, 樊跃平, 饶本强. 大剂量维生素C联合FOLFOX6治疗结直肠癌的临床疗效. 肿瘤代谢与营养电子杂志. 2024; 11: 499-504.https://doi.org/10.16689/j.cnki.cn11-9349/r.2024.04.009
[30] 饶本强, 王诗婉, 石汉平, 曲晋秀, 路帅, 王冰, et al. 肿瘤大剂量维生素C治疗专家共识(2024年). 肿瘤代谢与营养电子杂志.2024; 11: 181-186. https://doi.org/10.16689/j.cnki.cn11-9349/r.2024.02.006
[31] 王诗婉, 王欣, 曲晋秀, 何嘉, 赵媛, 饶本强. 基于药代动力学特点的肿瘤大剂量维生素C临床增效策略. 肿瘤代谢与营养电子杂志. 2024; 11: 270-275.https://doi.org/10.16689/j.cnki.cn11-9349/r.2024.02.019
[32] 中国抗癌协会. 恶性肠梗阻治疗中国专家共识(2023年). 肿瘤代谢与营养电子杂志.2023; 10: 730-737. https://doi.org/10.16689/j.cnki.cn11-9349/r.2023.06.006
[33] 熊秦, 王万州, 罗小云, 饶本强. 手术患者合并静脉血栓栓塞症的危险因素分析. 医学研究杂志. 2023; 52: 79-83.
[34] 曲晋秀, 王欣, 饶本强. 中医药强化大剂量维生素C治疗肿瘤作用.肿瘤代谢与营养电子杂志. 2023; 10: 319-324.https://doi.org/10.16689/j.cnki.cn11-9349/r.2023.03.003
[35] 张展志, 刘星凯, 闫凤彩, 饶本强, 汪福意, 石汉平. 18例孤立性纤维瘤的临床病理特点分析及蛋白质组学探索. 现代肿瘤医学. 2023; 31: 2086-2094.
[36] 王欣, 饶本强. 肿瘤大剂量维生素C精准强化治疗. 肿瘤代谢与营养电子杂志.2023; 10: 307-312+302. https://doi.org/10.16689/j.cnki.cn11-9349/r.2023.03.001
[37] 熊秦, 王万州, 饶本强, 罗小云. 不同科室新发静脉血栓栓塞症患者防治现状与对策分析. 中国临床研究. 2022; 35: 1424-1429.https://doi.org/10.13429/j.cnki.cjcr.2022.10.019
[38] 王玉莹, 石汉平, 饶本强. 粪菌移植的临床操作与应用. 肿瘤代谢与营养电子杂志. 2022; 9: 390-395.https://doi.org/10.16689/j.cnki.cn11-9349/r.2022.03.019
主编或者副主编的著作/译著:
《肿瘤微生态学》主编 科学出版社 202106
《肿瘤大剂量维生素C精准强化治疗》 主编 科学出版社 202403
重要奖项:
以TF为靶点的抗肿瘤血管治疗 科技进步 2016
几种消化系统恶性肿瘤分子标记物的研究 科技进步 2003
针灸治疗肿瘤的系列研究 科技进步 2001
维和二级医院护理工作的组织与实施 科技进步 2007
重组人肿瘤坏死因子抗大肠癌的作用及其机理研究 科技进步 2001
肿瘤营养诊疗关键技术研究与推广 科技进步 省部一等奖 2021
血清免疫抑制酸性蛋白与恶性肿瘤辅助诊断 科技进步 2000
HSV-TK和B7联合基因治疗乳腺癌的实验研究 科技进步 2003
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