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(1)国家自然科学基金委员会, 面上项目, 82472275, 2',3'-环核苷酸 3'-磷酸二酯酶通过调节线粒体稳态减轻 ZIKV感染所致神经髓鞘损伤, 2025-01-01 至 2028-12-31
发表论文:
[1] Yang W, Liu L B, Liu F L, Wu Y H, Zhen Z D, Fan D Y, Sheng Z Y, Song Z R, Chang J T, Zheng Y T, An J, Wang P G. Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation. Nat Commun, 2023, 14(1): 2476.
[2] Wu YH, Cui X, Yang W, Fan D, Liu D, Wang P, An J. Zika Virus Infection in Hypothalamus Causes Hormone Deficiencies and Leads to Irreversible Growth Delay and Memory Impairment in Mice. Cell Reports, 2018, 25(6): 1537-1547.
[3] Zhen Z D, Wu N, Fan D Y, Ai J H, Song Z R, Chang J T, Wang P G, Wu YH, An J. Growth hormone attenuates the brain damage caused by ZIKV infection in mice. Virol Sin, 2022, 37(4): 601-609.
[4] Wu YH, Cui X, Wu N, Song R, Yang W, Zhang W, Fan D, Chen Z, An J. A unique case of human Zika virus infection in association with severe liver injury and coagulation disorders. Sci Rep, 2017, 7(1): 11393.
[5] Yang W, Wu Y H, Liu S Q, Sheng Z Y, Zhen Z D, Gao R Q, Cui X Y, Fan D Y, Qin Z H, Zheng A H, Wang P G, An J. S100A4+ macrophages facilitate zika virus invasion and persistence in the seminiferous tubules via interferon-gamma mediation. PLoS Pathog, 2020, 16(12): e1009019.
[6] Cui X, Wu YH, Fan D, Gao N, Ming Y, Wang P, An J. Peptides P4 and P7 derived from E protein inhibit entry of dengue virus serotype 2 via interacting with β3 integrin. Antiviral Research, 2018, 155: 20-27.
专利:
(1) 安静; 吴艳花; 崔小云; 范东瀛; 杨威 ; 登革病毒E蛋白阻断肽P4及其应用, 2019-3-12, 中国, ZL 2016 1 0206242.5 (专利)
(2) 安静; 吴艳花; 崔晓云; 范东瀛; 杨威 ; 登革病毒E蛋白阻断肽P7及其应用, 2019-3-12, 中国, ZL 2016 1 0206710.9 (专利)
(3) 安静; 王培刚; 杨威; 吴艳花; 刘利波; 范东瀛 ; 氯硝柳胺在制备预防和/或治疗缓解寨卡病毒感染 所致睾丸损伤的药物中的应用, 2022-04-22, 中国, ZL 2021 1 0882893.7 (专利)
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