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毕业于首都医科大学，就职于北京友谊医院泌尿外科，擅长肾癌、前列腺癌、膀胱癌、肾盂输尿管癌的微创治疗及围手术期的辅助治疗、精准治疗等，开展前列腺激光、等离子剜除术，对于前列腺PSA增高患者给予无痛经会阴饱和前列腺穿刺术（开展日间手术），开展泌尿系结石开展各种微创治疗。2016年在美国耶鲁大学医学院作为访问学者学习一年。已经获得首都医科大学博士学位。近年来发表SCI及核心期刊文章20余篇。
主持北京市自然科学基金面上项目（ARDAP@SPION-MNPs复合纳米颗粒触发人肾癌干细胞铁死亡的机制研究，2022-1至2024-12）
主持内蒙古自治区首府地区公立医院高水平临床专科建设科技项目（AbB7-H3-800CW探针NIR-II荧光成像技术实时评估前列腺癌根治术标本切缘状态的临床研究，2024-09至2027-08）
1.Tian Y, Shen H, Li L, Jia X, Liu J, Hu Z, Wang L, Tian J. Enhancing surgical outcomes: accurate identification and removal of prostate cancer with B7-H3-targeted NIR-II molecular imaging.EUR J NUCL MED MOL I. Eur J Nucl Med Mol Imaging. 2024;51(9):2569-2582.
2.Hongliang Shen, Zixiang Geng, Xiaoli Nie, Te Liu. Erianin Induces Ferroptosis of Renal Cancer Stem Cells via Promoting ALOX12/ P53 mRNA N6-methyladenosine Modification.J Cancer. 2023;14(3):367-378.
3.Michela Puxeddu, Hongliang Shen, Ruoli Bai, Antonio Coluccia, Marianna Bufano, Marianna Nalli, Jessica Sebastiani, Diego Brancaccio, Eleonora Da Pozzo, Chiara Tremolanti, Claudia Martini, Viviana Orlando, Stefano Biagioni, Maria Stefania Sinicropi, Jessica Ceramella, Domenico Iacopetta , Addolorata Maria Luce Coluccia, Ernest Hamel, Te Liu, Romano Silvestri, Giuseppe La Regina. Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia. Eur J Med Chem. 2021;221:113532. （共一）
4.Michela Puxeddu, Hongliang Shen, Ruoli Bai, Antonio Coluccia, Marianna Nalli, Carmela Mazzoccoli, Eleonora Da Pozzo, Chiara Cavallini, Claudia Martini, Viviana Orlando, Stefano Biagioni, Cristina Mazzoni, Addolorata Maria Luce Coluccia, Ernest Hamel, Te Liu, Romano Silvestri, Giuseppe La Regina. Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies. Eur J Med Chem. 2020;185:111828. （共一）
5.Qiang Liu, Hongliang Shen #, Andrew Naguib, Robert M Weiss, Darryl T Martin.Knocking down claudin receptors leads to a decrease in prostate cancer cell migration, cell growth, cell viability and clonogenic cell survival. Mol Biomed.2021;2(1):31.（共一）
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