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丁楠，首都医科大学附属北京世纪坛医院，生物医学创新中心。毕业于中国科学院北京基因组研究所，专注于感染免疫领域的生物信息学研究，从一维基因组（SNP/SNV变异）、二维基因组（表观遗传修饰、RNA可变剪切、非编码RNA）、三维基因组（3D基因组结构重塑），建立多组学数据整合联动分析的研究方法，系统阐述基因的程序性转录调控机制，挖掘感染性疾病、肿瘤、衰老、自免病等的致病机制。以第一作者（含共同）在National Science Review，Nature Communications, The Innovation，Clinical Infectious Diseases等杂志发表12篇文章，总影响因子132，最高影响因子32。主持国家自然科学基金2项。发明专利1项，软件著作权1项。
国家自然科学基金面上项目，脓毒症中Hp1相关异染色质重组介导的粒细胞免疫记忆研究，在研。
国家自然科学基金青年项目，不同毒力MTB菌株与宿主巨噬细胞互作过程中的非编码RNA免疫调节机制网络研究，结题。
国家自然科学基金面上项目，脓毒症中Hp1相关异染色质重组介导的粒细胞免疫记忆研究，在研。
国家自然科学基金青年项目，不同毒力MTB菌株与宿主巨噬细胞互作过程中的非编码RNA免疫调节机制网络研究，结题。
1. Fu J#, Zhang J#, Yang L#, Ding N#, Yue L#, Zhang X, Lu D, Jia X, Li C, Guo C, Yin Z, Jiang X, Zhao Y, Chen F*, Zhou D*. Precision Methylome and in vivo Methylation Kinetics Characterization of Klebsiella Pneumoniae. Genomics, Proteomics & Bioinformatics, 2022, 20(2):418-434.
2. Zhang J#, Ding N#, Ren L#, Song R#, Chen D#, Zhao X, Chen B, Han J, Li J, Song Y, Di L, Han K, Yu F, Xie R, Chen Z, Xie W, Liu J, Cen S, Bi Y, Wu AR*, Zhang F*, Chen C*, Zeng H*. COVID-19 reinfection in the presence of neutralizing antibodies. National Science Review, 2021, 8(4):nwab006.
3. Zhang J#, Ding N#, Song Y#, Song R#, Pan Y#, Wang L, Yan S, Wang Q, Ma S, Wei L, Yu F, Lu L*, Zhang F*, Chen C*, Zeng H*. Phylogenomic tracing of asymptomatic transmission in a COVID-19 outbreak. The Innovation. 2021. 2(2):100099.
4. Du P#, Ding N#, Li J#, Zhang F#, Wang Q#, Chen Z#, Song C, Han K, Xie W, Liu J, Wang L, Wei L, Ma S, Hua M, Yu F, Wang L, Wang W, An K, Chen J, Liu H, Gao G, Wang S, Huang Y, Wu AR, Wang J*, Liu D*, Hui Zeng H* & Chen C*. Genomic surveillance of COVID-19 cases in Beijing. Nature Communications, 2020, 11(1):5503.
5. Huang H#, Ding N#, Yang T#, Li C#, Jia X#, Wang G#, Zhong J, Zhang J, Jiang G, Wang S, Zong Z, Jing W, Zhao Y, Xu S, Chen F*. Cross-sectional whole-genome sequencing and epidemiological study of multidrug-resistant Mycobacterium tuberculosis in China. Clinical Infectious Disease, 2019, 69(3):405-413.
6. Lv L#, Li C#, Zhang X#, Ding N#, Cao T#, Jia X, Wang J, Pan L, Jia H, Li Z, Zhang J,Chen F*, and Zhang Z*. RNA Profiling Analysis of the Serum Exosomes Derived from Patients with Active and Latent Mycobacterium tuberculosis Infection. Frontiers in Microbiology, 2017, 8:1051.
7. Ding N#, Zhang Z#, Yang W, Ren L, Zhang Y, Zhang J, Li Z, Zhang P, Zhu X, Chen X*, Fang X*.Transcriptome analysis of monozygotic twin brothers with childhood primary myelofibrosis. Genomics Proteomics & Bioinformatics, 2017, 15(1):37-48.
8. Ding N#, Xi J#, Li Y#, Xie X, Shi J, Zhang Z, Li Y, Fang F, Wang S, Yue W, Pei X*, Fang X*. Global transcriptome analysis to identify interactions between coding and noncoding RNAs in human erythroid differentiation. Frontiers of Medicine, 2016,10(3):297-310.
9. Wang D#, Wang J#, Ding N#, Li Y, Yang Y, Fang X*, Zhao H*. MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation. Biochemical and Biophysical Research Communications, 2016, 473(4):959-965.
10. Wang J#, Ding N#, Li Y#, Cheng H#, Wang D, Yang Q, Deng Y, Yang Y, Li Y, Ruan X, Xie F, Zhao H*, Fang X*. Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells. Oncotarget, 2015, 6(24):20636-20649.
11. Zhang Q#, Ding N#, Xiong Q, Zheng J, Li Z, Li Y, Li Q, Fang X, Zhang Z*. Regulatory Roles of KLF3 in Hematopoiesis of K562 Leukemia Cells. Journal of Stem Cell Research & Therapy, 2015, 5(10):e1-e9.
12. Ding N#, Wang S#, Yang Q#, Li Y, Cheng H, Wang J, Wang D, Deng Y, Yang Y, Hu S, Zhao H*, Fang X*. Deep sequencing analysis of microRNA expression in human melanocyte and melanoma cell lines. Gene, 2015, 572(1):135-145.
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