团队成员享受每天撸狗的福利。

国家自然科学基金委员会, 青年科学基金项目, 32100783, 自闭症相关基因CHD8在非人灵长类大脑发育中的作用, 2022-01-01 至 2024-12-31, 30万元, 在研, 主持 

中国博士后科学基金会, 面上资助, 2019M653106, Shank3突变自闭症家犬模型的创建, 2019-05 至 2020-11, 8万元, 结题, 主持

国家自然科学基金委员会, 青年科学基金项目, 32100783, 自闭症相关基因CHD8在非人灵长类大脑发育中的作用, 2022-01-01 至 2024-12-31, 30万元, 在研, 主持 

中国博士后科学基金会, 面上资助, 2019M653106, Shank3突变自闭症家犬模型的创建, 2019-05 至2020-11, 8万元, 结题, 主持

(1)Feipeng Zhu#; Qi Shi#; Yong-Hui Jiang; Yong Q Zhang*; Hui Zhao*;Impaired synaptic function and hyperexcitability of the pyramidal neurons in the prefrontal cortex of autism-associated Shank3 mutant dogs, Molecular Autism, 2024, 15(1): 9 (共同通讯作者)

(2) Rui Tian#; YuanLi#; Hui Zhao#; Wen Lyu; Jianping Zhao; Xiaomin Wang; Heng Lu; HuijuanXu; Wei Ren; Qing-quan Tan; Qi Shi; Guo-dong Wang; Ya-ping Zhang; Liangxue Lai; Jidong Mi*; Yong-hui Jiang*; Yong Q. Zhang*; Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing, Molecular Psychiatry, 2023, 28(9): 3739-3750 (共同第一作者)

(3) Bang Li#; Hui Zhao#; Zhuchi Tu#; Weili Yang#; Rui Han; Lu Wang; Xiaopeng Luo; Mingtian Pan; Xiusheng Chen; Jiawei Zhang; Huijuan Xu; Xiangyu Guo; Sen Yan; Peng Yin;Zhiguang Zhao; Jianrong Liu; Yafeng Luo; Yuefeng Li; Zhengyi Yang; Baogui Zhang; Zhiqiang Tan; Hao Xu; Tianzi Jiang; Yong-hui Jiang; Shihua Li; Yong Q. Zhang*; Xiao-Jiang Li*; CHD8 mutations increase gliogenesis to enlarge brain size in the non-human primate, Cell Discovery, 2023, 9(1): 27. DOI:10.1038/s41421-023-00525-3 (共同第一作者)

(4)Huilin Hong, Chao Guo, Xueru Liu, Liguang Yang, Wei Ren, Hui Zhao, Yuan Li, Zhongyin Zhou, Sin Man Lam, Jidong Mi, Zhentao Zuo, Cirong Liu, Guo-Dong Wang, Yan Zhuo, Ya-ping Zhang, Yixue Li, Guanghou Shui, Yong Q. Zhang*, Ying Xiong*. Differential effects of social isolation on oligodendrocyte development in different brain regions: insights from a canine model. Front Cell Neurosci,2023, 17:1201295. DOI: 10.3389/fncel.2023.1201295

(5) Hui Zhao, Enqi Liu, Yong Q. Zhang, Dog models of human atherosclerotic vascular diseases. Mammalian Genome, 2022, 34(2):262-269. DOI: 10.1007/s00335-022-09965-w (invited review)

(6) Hui Zhao#, Jianping Zhao#, Di Wu#, Zhaolin Sun#, Yang Hua, Min Zheng, Yumei Liu, Qi Yang, Xiahe Huang, Yuan Li, Yueshan Piao, Yingchun Wang, Sin Man Lam, Huijuan Xu, Guanghou Shui, Yongjun Wang, Haifeng Yao, Liangxue Lai, Zhuo Du, Jidong Mi*,Enqi Liu*, Xunming Ji*; Yong Q. Zhang*. Dogs lacking Apolipoprotein E show advanced atherosclerosis leading to apparent clinical complications. Sci China Life Sci. 2022, 65(7):1342-1356. DOI: 10.1007/s11427-021-2006-y. (共同第一作者)

(7)Huilin Hong, Zhiguang Zhao, Xiahe Huang, Chao Guo, Hui Zhao, Guo-Dong Wang, Ya-Ping Zhang, Jian-ping Zhao, Jianhui Shi, Qing-Feng Wu, Yong-hui Jiang,Yingchun Wang, Lei M. Li, Zhuo Du, Yong Q. Zhang* and Ying Xiong*, Brain proteome comparison reveals specific molecular pathways conserved in dog and human. Mol Cell Proteomics, 2022, DOI: 10.1016/j.mcpro.2022.100261

(8) Hui Zhao#; Qiqi Wang#; Ting Yan; Yu Zhang; Hui-juan Xu; Hao-peng Yu; Zhuchi Tu;Xiangyu Guo; Yong-hui Jiang*; Xiao-jiang Li; Huihui Zhou*; Yong Q. Zhang*; Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates, Translational Psychiatry, 2019, 9(1): 0-267. (共同第一作者)

(9)Zhuchi Tu#, Hui Zhao#, Bang Li#, Sen Yan, Lu Wang, Yongjin Tang, ZhujunLi, Dazhang Bai, Caijuan Li, Yingqi Lin, Yuefeng Li, Jianrong Liu, Hao Xu, Xiangyu Guo, Yong-hui Jiang*, Yong Q. Zhang* and Xiao-Jiang Li*,CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms, Human Molecular Genetics, 2019, 28(4),561–571. (共同第一作者)

(10) Hui Zhao, Yong-hui Jiang, and Yong Q. Zhang. Modeling Autism in Non-human Primates: Opportunities and Challenges. Autism Research, 2018, 11, 686-694. (invited review)

(11) Hui Zhao#; Zhuchi Tu#; Huijuan Xu; Sen Yan; Huanhuan Yan; Yinghui Zheng; Weili Yang; Jiezhao Zheng; Zhujun Li; Rui Tian; Youming Lu; Xiangyu Guo; Yong-hui Jiang*; Xiao-Jiang Li*; Yong Q. Zhang*; Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate, Cell Research, 2017, 27(10): 1293-1297 (共同第一作者)

(12) Wenhua Li, Aiyu Yao, Hui Zhi, Kuldeep Kaur, Yong-chuan Zhu, Mingyue Jia, Hui Zhao, Qifu Wang, Shan Jin, Guoli Zhao, Zhi-Qi Xiong, and Yong Q. Zhang. Angelman syndrome protein Ube3a regulates synaptic growth and endocytosis by inhibiting bone morphogenetic protein signaling in Drosophila. PLoS Genetics, 2016, 12(5):e1006062, DOI:10.1371/journal.pgen.1006062

(13) Hui Zhao, Yongchao Zhang, and Yong Q. Zhang. Recent progresses in molecular genetics of autism spectrum disorders. Hereditas (beijing), 2015, 37, 845-854.