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冯瑾，首都医科大学基础医学院免疫学系副教授。2010 -2016年任职中国科学院生物物理所感染免疫国家重点实验室助理研究员，2017-2021年就读清华大学基础医学院免疫所，获博士学位，2022年任职首都医科大学基础医学院免疫系副教授、硕士研究生导师，从事神经免疫学领域的研究工作，主要研究方向为神经退行性疾病的免疫调节机制及干预策略。多年来主持和参与国家自然科学基金委面上项目、应急管理项目、重点项目和国家重点研发（973）等多个国家级项目，迄今已在Cell Research、Nature Communication、 Science Immunology、The Journal of Immunology、Cellular & MolecularImmunology等知名期刊发表多篇高水平论文。担任Signal Transduction andTargeted Therapy、MedComm、Advanced Science等多个SCI杂志审稿人。
1. 国家自然科学基金应急管理项目, 31540014, 肝内淋巴滤泡在丙型肝炎病毒慢性感染过程中发挥的作用及调控机制的研究, 2016/01-2016/12, 已结题, 主持
2. 国家自然基金面上项目，免疫抑制性Ly49+CD8+T细胞在阿尔兹海默症中的作用及其作用机制的研究, 2024/01-2027/12, 主持
1. 国家自然科学基金应急管理项目, 31540014, 肝内淋巴滤泡在丙型肝炎病毒慢性感染过程中发挥的作用及调控机制的研究, 2016/01-2016/12, 已结题, 主持
2. 国家自然基金面上项目，免疫抑制性Ly49+CD8+T细胞在阿尔兹海默症中的作用及其作用机制的研究, 2024/01-2027/12, 主持
1. Yeyu Huang, Guoxin Zhang, Sheng Li, Jin Feng, Zhentao Zhang. Innate and adaptive immunity in neurodegenerative disease. Cellular and Molecular Life Sciences, 2025 82 (1), 68
2. Ziqi Liang, Zhimin Li, Dan Zhang, Xing Luo, Qiang Liu, Dezhe Qin, Min Wang, Zhiheng Xu, Jin Feng, Jinting He, Weixiang Guo.Dual recombinase-mediated intersectional genetics defines the functional heterogeneity of neural stem cells in adult hippocampus. Molecular Psychiatry, 2025 1-17
3. S Chen, Z Li, J Feng, Y Quan, J He, J Hao, Z Dong. Dual Activity of Type III PI3K Kinase Vps34 is Critical for NK Cell Development and Senescence. Advanced Science, 2024 2309315
4. DanLi, Wei Xiong, Yuande Wang, Jin Feng, Yuexi He, Juan Du , Jing Wang, MeixiangYang, Hui Zeng, Yong-Guang Yang, Ning Wu, Shasha Chen, Zhongjun Dong. SLAMF3and SLAMF4 are immune checkpoints that constrain macrophage phagocytosis ofhematopoietic tumors. Science Immunology. 2022 Jan 21;7(67).
5. XiaoqianZhang*, Jin Feng*, Shasha Chen, Haoyan Yang, Zhongjun Dong. Synergizedregulation of NK cell education by NKG2A and specific Ly49 family members.Nature Communication, 2019 10:5010
6. Junming He, Yuande Wang, Tian Liu, Guangao Liu, Shasha Chen, Qiaozhen Li, Yuhe Quan, Haoyan Yang, Jin Feng, Song Wang, Meixiang Yang, Zhongjun Dong.Stage-specific requirement of kinase PDK1 for NK cells development and activation. Cell Death & Differentiation, 2019 26 (10), 1918-1928
7. ChaoZhang*, Jin Feng*, Jun Du, Zhiyong Zhuo, Shuo Yang, Weihong Zhang, WeihongWang, Guangxun Meng, Yangxin Fu, Baidong Hou, Hong Tang. Macrophage-derivedIL-1promotes sterile inflammation in mouse model of acetaminophenhepatotoxicity. Cellular& Molecular Immunology，2018;15(11):973-982.
8. FeifeiMa*, Jin Feng*, Chao Zhang*, Yulin Li, Guanming Qi, Huihua Li, Yuzhang Wu,Yangxin Fu, Yang Zhao, Hairong Chen, Jie Du, and Hong Tang. The Requirement ofCD8+ T Cells To Initiate and Augment Acute Cardiac Inflammatory Response toHigh Blood Pressure. The Journal of Immunology, 2014, 192: 3365–3373
9. JizhengChen*, Yang Zhao*, Chao Zhang*, Hairong Chen*, Jin Feng, Xiumei Chi, Yu Pan,Jun Du, Min Guo, Huang Cao, Honghe Chen, Zilong Wang, Rongjuan Pei, Qian Wang,Lei Pan, Junqi Niu, Xinwen Chen, Hong Tang. Persistent hepatitis C virusinfections and hepatopathological manifestations in immune-competent humanizedmice. Cell Research, 2014 24:1050-1066.
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