1. 国家自然科学基金面上项目（82371565）：骨髓脂肪细胞棕色化通过诱导NK细胞代谢重编程抑制其衰老的机制研究，2024/01-2027/12，49万，在研，主持

2. 北京市自然科学基金项目面上专项（M21007）：调节型NK细胞在新型冠状病毒肺炎进展中的作用及机制研究，2021/01-2023/12，30万，在研，主持

3. 国家自然科学基金青年项目（81902895）：Styk1激酶调节NK细胞迁移发挥抗肿瘤免疫作用的机制研究，2020/01-2022/12，21.5万，已结题，主持

4. 北京市自然科学基金青年项目（7184218）：PDK1激酶调节脓毒症中巨噬细胞极化平衡的分子机制研究，2018/01- 2019/12，10万，已结题，主持

(1) Lihua Yu#, Lei Sun#, Xiaoli Liu, Xinhui Wang, Huiwen Yan,Qing Pu, Yuqing Xie, Yuyong Jiang, Juan Du(杜娟)*, Zhiyun Yang*, The imbalance of NKG2A and NKG2D expressionis involved in NK cell immunosuppression and tumor progression of HBV‐HCC patients, Hepatology Research, 2023,2023(13877)：1-15.（Q2,IF：4.2）

(2) LihuaYu#, Xiaoli Liu#, Xinhui Wang, Huiwen Yan, Qing Pu, Yuqing Xie, Juan Du(杜娟)* andZhiyun Yang*, Glycometabolism-related gene signature of hepatocellularcarcinoma predicts prognosis and guides immunotherapy. Frontiers in Cell andDevelopmental Biology, 2022，10:940551. doi: 10.3389/fcell.2022.940551(Q1,IF：5.5)

（3）Qing Pu#, LihuaYu#, Xinhui Wang, Huiwen Yan, Yuqing Xie, Juan Du(杜娟)*, Zhiyun Yang*, Establishment ofNomogram Model for Minimally Invasive Treatment of Small HepatocellularCarcinoma Based on CD8+T Cell Counts. OncoTargetsand Therapy 2022:15 925–940 (Q2,IF：4.0)

（4）XinyueWang#, Di Wang#, Juan Du(杜娟)#,Yuqing Wei, Rui Song, Beibei Wang, Shuang Qiu, Bei Li, Leidan Zhang, YongqinZeng, Hongxin Zhao* and Yaxian Kong*, High Levels of CD244 Rather Than CD160Associate With CD8+ T-Cell Aging, Frontiers in Immunology, 2022, 13:853522 (Q1,IF:7.3)

（5）Xinyue Wang#,Leidan Zhang#, Juan Du(杜娟)#, Yuqing Wei, Di Wang, Chuan Song, Danying Chen, Bei Li, MeiqingJiang, Mengyuan Zhang, Hongxin Zhao* and Yaxian Kong*, Decreased CD73+Double-Negative T Cells and Elevated Level of Soluble CD73 Correlated With andPredicted Poor Immune Reconstitution in HIV Infected Patients AfterAntiretroviral Therapy, Frontiers in Immunology, 2022, 13:869286 (Q1,IF: 7.3，引用次数：3)

(6) Juan Du(杜娟)#,Lirong Wei#, Guoli Li#, Mingxi Hua#, Yao Sun, Di Wang, Kai Han,Yonghong Yan,Chuan Song, Rui Song, Henghui Zhang, Junyan Han*,Jingyuan Liu*, Yaxian Kong*, PersistentHigh Percentage of HLA-DR+CD38high CD8+ TCells Associated With Immune Disorder and Disease Severity of COVID-19., Frontiers in Immunology, 2021 Sep 9;12:735125.,doi:10.3389/fimmu.2021.735125 (Q1,IF: 7.3，引用次数：27)

(7)Lihua Yu#, Xiaoli Liu#, Xinhui Wang, Fengna Yan, PengWang, Yuyong Jiang, Juan Du(杜娟)*，ZhiyunYang*, TIGIT+ TIM-3+ NK cells are correlated with NK cellexhaustion and disease progression in patients with hepatitis B virus‑related hepatocellularcarcinoma., OncoImmunology，2021，10:1, 1942673（Q1,IF: 7.2，引用次数：32）

(8)Yongqin Zeng, Xiuzhi Lv, Juan Du(杜娟)*, Natural killer cell‑based immunotherapy forlung cancer: Challenges and perspectives (Review)., ONCOLOGY REPORTS 46: 232, 2021 (Q2,IF：4.2，引用次数：13)

(9)Yuexi He#，Juan Du(杜娟)#，Zhongjun Dong*. Myeloiddeletion of phosphoinositide-dependent kinase-1 enhances NK cell-mediatedantitumor immunity by mediating macrophage polarization.，OncoImmunology，2020，9:1, 1774281 （Q1,IF: 7.2，引用次数：10）

(10)Di Wang#, Juan Du(杜娟)#, Yangzi Song, Beibei Wang, Rui Song, Yu Hao, Yongqin Zeng,Jiang Xiao, Hong Zheng, Hui Zeng, Hongxin Zhao*, Yaxian Kong*. CD70 contributesto age-associated T cell defects and overwhelming inflammatory responses.，Aging，2020，19;12, 18632 (Q2,IF: 5.2，引用次数：4)

(11)Juan Du(杜娟)#, GuoliLi#, Mingxi Hua, Junyan Han, Yu Hao, Hui Zeng , AngLi, Yaxian Kong*. PDK1/mTOR Signaling in Myeloid Cells Differentially Regulatesthe Early and Late Stages of Sepsis., Mediators of Inflammation, 2020, 7:25, 9(Q2,IF:4.6，引用次数2)